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  • Abstract Number: 1265 • 2013 ACR/ARHP Annual Meeting

    Initial Benchmarking Of The Quality Of Medical Care Of Children and Adolescents With Lupus

    Ahmad I. Zaal1, Julia G. Harris2, Clovis A. Silva3, Marco F. Sliva4, Jiha Lee5, Alexandria J. Greenler6, Simone Appenzeller7, Maraisa Centeville7, HaiMei Liu8, Joshua D. Pendl5, Jennifer L. Huggins1, Jessica M. Sage6 and Hermine Brunner9, 1Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2Children's Hospital of Wisconsin, Milwaukee, WI, 3Children's Institute, Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, Brazil, 4Pediatric Rheumatology Unit-Children’s Institute,, Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, Brazil, 5Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 6Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 7Medicine, Faculty of Medical Science, State University of Campinas Unicamp, São Paulo, Brazil, 8Children's Hospital of Fundan University, Shanghai, China, 9Cincinnati Children's Hospital Medical Center, Cincinnati, OH

    Background/Purpose: Recently, 26 quality indicators (QI) for childhood-onset systemic lupus erythematous (cSLE) have been developed based on international consensus and scientific evidence. QI are defined…
  • Abstract Number: 1267 • 2013 ACR/ARHP Annual Meeting

    Impact Of Disease Duration On Vascular Surrogates Of Early Atherosclerosis In Childhood-Onset Systemic Lupus Erythematosus

    Julie Barsalou1, Timothy J. Bradley2, Cameron Slorach2, Lawrence W.K. Ng3, Deborah M. Levy4 and Earl D. Silverman1, 1Rheumatology, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada, 2Cardiology, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada, 3Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, 4Rheumatology, The Hospital for Sick Children and University of Toronto, Toronto, ON, Canada

    Background/Purpose: Cardiovascular disease is a leading cause of morbidity and mortality in adults with systemic lupus erythematosus. Exposure to atherogenic risk factors in childhood-onset SLE…
  • Abstract Number: 1268 • 2013 ACR/ARHP Annual Meeting

    Long-Term Follow-Up Of a Pediatric Lupus Cohort: Transition Of Care and Health Related Outcomes

    Susanna Felsenstein1, Anusha Ramanathan2, Beatriz Gonzalez3 and Andreas Reiff4, 1Pediatric Infectious Diseases, Children's Hospital Los Angeles, Los Angeles, CA, 2Rheumatology, Children's Hospital Los Angeles, Los Angeles, CA, 3Pediatric Rheumatology, Children's Hospital Los Angeles, Los Angeles, CA, 4Division of Rheumatology, Children's Hospital Los Angeles, Los Angeles, CA

    Background/Purpose: Transition from pediatric to adult care is a difficult process with the potential for negative impact on medical, psychological and social outcomes.  In this…
  • Abstract Number: 1269 • 2013 ACR/ARHP Annual Meeting

    The Development Of a Mobile Application For Adolescents and Young Adults With Lupus

    Natasha M. Ruth1, Deborah M. Levy2, Andrea Regina3, Christy Taberner4, Edith M. Williams5 and Miriam Kaufman6, 1Pediatric Rheumatology, Medical University of South Carolina, Charleston, SC, 2Rheumatology, The Hospital for Sick Children and University of Toronto, Toronto, ON, Canada, 3Department of Psychology, The Hospital for Sick Children, Toronto, ON, Canada, 4Mohawk College, Toronto, ON, Canada, 5Institute for Partnerships to Eliminate Health Disparities, University of South Carolina, Columbia, SC, 6Adolescent Medicine, The Hospital for Sick Children, Toronto, ON, Canada

    Background/Purpose: Young adults with lupus need reliable disease-specific knowledge that includes information about lupus, the effect of lupus and lupus medication on their lives, and…
  • Abstract Number: 1270 • 2013 ACR/ARHP Annual Meeting

    Risk Factors For The Development Of Avascular Necrosis In Pediatric Systemic Lupus Erythematosus Patients

    Reut Gurion1, Howard Yang2, Hong Li3, Stephanie Frenkian2, Kathleen A. Haines4, Jennifer E. Weiss5, Yukiko Kimura5, Andrew S. Zeft6, Angela B. Robinson7, Suzanne C. Li8 and for The CARRA Registry Investigators9, 1Pediatric Infectious Diseases, Rheumatology, and Geographic Medicine, Rainbow Babies and Children's Hospital / Case Medical Center, Cleveland, OH, 2Joseph M Sanzari Children’s Hospital, Hackensack University Medical Center, Hackensack, NJ, 3Case Western Reserve University, Cleveland, OH, 4Department of Pediatrics, Joseph M Sanzari Children’s Hospital, Hackensack University Medical Center, Hackensack, NJ, 5Pediatric Rheumatology, Joseph M Sanzari Children’s Hospital, Hackensack University Medical Center, Hackensack, NJ, 6Pediatric Institute, Department of Pediatric Rheumatology, Cleveland Clinic Foundation, Cleveland, OH, 7Pediatric Infectious Disease, Rheumatology and Geographic Medicine, Rainbow Babies and Children's Hospital / Case Medical Center, Cleveland, OH, 8Pediatrics, Joseph M Sanzari Children’s Hospital, Hackensack University Medical Center, Hackensack, NJ, 9Duke Clinical Research Institute, Durham, NC

    Background/Purpose: Avascular necrosis (AVN) is a serious morbidity of pediatric systemic lupus erythematosus (pSLE) associated with disability, impaired quality of life, and increased cost of…
  • Abstract Number: 1271 • 2013 ACR/ARHP Annual Meeting

    Longitudinal Disease Trajectory Of Juvenile Dermatomyositis

    Lily Siok Hoon Lim1,2, Eleanor Pullenayegum3, Dafna D. Gladman4, Earl D. Silverman5 and Brian M. Feldman6, 1Pediatric Rheumatology, Hospital for Sick Children, Toronto, ON, Canada, 2Institute of Health Policy Management and Evaluation, University of Toronto, Toronto, ON, Canada, 3Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada, 4Division of Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 5Rheumatology, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada, 6Rheumatology, Hospital for Sick Children, Toronto, ON, Canada

    Background/Purpose: 1) To determine the longitudinal disease activity trajectory of an inception cohort of Juvenile Dermatomyositis (JDM) patients, 2) To identify predictor(s) for longitudinal disease…
  • Abstract Number: 1272 • 2013 ACR/ARHP Annual Meeting

    Whole-Body Versus Thigh Magnetic Resonance Imaging In The Assessment Of Juvenile Dermatomyositis

    Clara Malattia1, Annalisa Madeo2, Marta Dellepiane3, Diliana Beleva3, Stefania Viola4, Alessandro Consolaro5, Nicolino Ruperto1 and Alberto Martini6, 1PRINTO, Genoa, Italy, 2Istituto G Gaslini, Pediatria II, Reumatologia, Genova, Italy, 3Istituto G. Gaslini, Pediatria 2, Genoa, Italy, 4Istituto G. Gaslini, Istituto Giannina Gaslini, Genova, Italy, 5Pediatria II, Istituto Giannina Gaslini, Genova, Italy, 6Istituto Giannina Gaslini, Pediatria II, Reumatologia, Paediatric Rheumatology International Trials Organisation (PRINTO) Coordinating Center, Genoa, Italy, Genoa, Italy

    Background/Purpose: MRI is a promising tool to assess disease activity in juvenile dermatomyositis (JDM). So far all MRI JDM studies focused on the thigh musculature.…
  • Abstract Number: 1273 • 2013 ACR/ARHP Annual Meeting

    Granulomatosis With Polyangiitis In Children Is More Severe Than In Adults. A Long-Term, Single Center, Follow Up Study

    Francesco Zulian1, Grazia Minardo2, Valeria Carraro3, Franco Schiavon3 and Giorgia Martini4, 1PRINTO, Genoa, Italy, 2Department of Pediatrics, University of Padua, Padua, Italy, 3Rheumatology Clinic, University of Padova, Padova, Italy, 4Department of Pediatrics,, University of Padua, Padua, Italy

    Background/Purpose: Granulomatosis with polyangiitis (GPA) is a rare disease in childhood. Treatment strategies and clinical approach are still mostly derived from adult GPA studies. The…
  • Abstract Number: 1274 • 2013 ACR/ARHP Annual Meeting

    Maternal Vitamin D, Fetal C-Reactive Protein and Brain Natriuretic Peptide Associate With The Development and Morbidity Of Cardiac Neonatal Lupus

    Amit Saxena1, Peter M. Izmirly2, Joanne H. Reed3, Sara Sahl2, Deborah Friedman4, Robert M. Clancy3 and Jill P. Buyon2, 1Rheumatology, New York University School of Medicine, New York, NY, 2Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, 3Medicine, New York University School of Medicine, New York, NY, 4Division of Pediatric Cardiology, New York Medical College, Valhalla, NY

    Background/Purpose: Women with anti-Ro antibodies face the risk of having a child with cardiac Neonatal Lupus (NL), characterized by congenital heart block and/or cardiomyopathy.  Biomarkers…
  • Abstract Number: 1275 • 2013 ACR/ARHP Annual Meeting

    Prenatal Exposure To Fluorinated Steroids Does Not Affect Long Term Morbidity In Cardiac Neonatal Lupus

    Amit Saxena1, Peter M. Izmirly2, Sara Sahl2, Deborah Friedman3 and Jill P. Buyon2, 1Rheumatology, New York University School of Medicine, New York, NY, 2Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, 3Division of Pediatric Cardiology, New York Medical College, Valhalla, NY

    Background/Purpose: Cardiac Neonatal Lupus (NL), characterized by inflammation and fibrosis of the conduction system, endocardium, and myocardium in anti-Ro exposed fetuses, results in significant morbidity…
  • Abstract Number: 1244 • 2013 ACR/ARHP Annual Meeting

    Low Bone Mineral Density In African-American Males May Be More Prevalent Than Previously Reported and Exhibits Association With Low BMI But Not Older Age – Results Of a Retrospective Cohort Analysis

    Khush Aujla1 and Vikas Majithia2, 1Division of Rheumatology, University of Mississippi School of Medicine, Jackson, MS, 2Div of Rheumatology, University of Mississippi Medical Center, Jackson, MS

    Background/Purpose: Osteoporosis (OP) in Males is prevalent and frequently under-recognized. There are a number of known demographic factors such as age, race and BMI as…
  • Abstract Number: 1235 • 2013 ACR/ARHP Annual Meeting

    Predictors Of Fracture In Patients With Osteopenia: Data From An Observational Cohort

    Kathryn Mitchell1, Peter Diggle1 and Marwan Bukhari1,2, 1Faculty of Health and Medicine, Lancaster, United Kingdom, 2Department of Rheumatology, Royal Lancaster Infirmary, Lancaster, United Kingdom

    Background/Purpose: The risk factors for osteoporotic fragility fractures are well documented in the literature and although they are associated with a diagnosis of established osteoporosis…
  • Abstract Number: 1236 • 2013 ACR/ARHP Annual Meeting

    Outcomes and Costs Of Sacral Insufficiency Fractures

    Shahryar Hadavi1, Sanam Kia1, Christian Dejaco2, Bhaskar Dasgupta2 and Frances Borg3, 1Rheumatology Department, Southend University Hospital, Westcliff-on-Sea, United Kingdom, 2Rheumatology, Southend University Hospital, Westcliff-on-Sea, United Kingdom, 3Rheumatology, Southend University Hospital, Westcliff-on-sea, United Kingdom

    Background/Purpose: Sacral insufficiency fracture (SIF) is a poorly recognised cause of lower back pain in the elderly with significant potential morbidity. Diagnosis is often slow…
  • Abstract Number: 1237 • 2013 ACR/ARHP Annual Meeting

    Denosumab Leads To Significantly Greater Increases In Bone Mineral Density Than Ibandronate and Risedronate In Postmenopausal Women At High Risk For Fracture Who Were Previously Treated With An Oral Bisphosphonate

    Jacques P. Brown1, Michael A. Bolognese2, Pei-Ran Ho3, Jesse Hall3, Christian Roux4, Henry G. Bone5, Sydney Bonnick6, Joop van den Bergh7, Irene Ferreira8, Prayashi Ghelani9, Paula Dakin3, Rachel B. Wagman3 and Chris Recknor10, 1CHU de Québec Research Centre and Laval University, Quebec City, QC, Canada, 2Bethesda Health Research Center, Bethesda, MD, 3Amgen Inc., Thousand Oaks, CA, 4Paris Descartes University, Paris, France, 5Michigan Bone and Mineral Clinic, Detroit, MI, 6Clinical Research Center of North Texas, Denton, TX, 7VieCuri Medical Centre and Maastricht University, Venlo, Netherlands, 8Amgen Inc., Cambridge, United Kingdom, 9Ovatech Solutions, London, United Kingdom, 10United Osteoporosis Centers, Gainesville, GA

    Denosumab Leads to Significantly Greater Increases in Bone Mineral Density Than Ibandronate and Risedronate in Postmenopausal Women at High Risk for Fracture Who Were Previously…
  • Abstract Number: 1238 • 2013 ACR/ARHP Annual Meeting

    Persistence At 12 Months With Denosumab (Prolia®) In Postmenopausal Women With Osteoporosis: Interim Results From a Prospective Observational Study

    Stuart L. Silverman1, Ethel Siris2, David L. Kendler3, Dea Belazi4, Jacques P. Brown5, Deborah T. Gold6, E. Michael Lewiecki7,8, Alexandra Papaioannou9, Christine Simonelli10, Irene Ferreira11, Paula Dakin12, Suresh Siddhanti12, Bradley Stolshek12 and Christopher Recknor13, 1Cedars-Sinai Medical Center, UCLA Center of Excellence, Los Angeles, CA, 2Columbia University, New York, NY, 3University of British Columbia, Vancouver, BC, Canada, 4AlchemiPharma LLC, Wayne, PA, 5CHU de Québec Research Centre and Laval University, Quebec City, QC, Canada, 6Duke University Medical Center, Durham, NC, 7University of New Mexico School of Medicine, Albuquerque, NM, 8New Mexico Clinical Research & Osteoporosis Center, Albuquerque, NM, 9Geriatric Medicine, McMaster University, Hamilton, ON, Canada, 10Health East Osteoporosis Care, Woodbury, MN, 11Amgen Inc., Cambridge, United Kingdom, 12Amgen Inc., Thousand Oaks, CA, 13United Osteoporosis Centers, Gainesville, GA

    Background/Purpose: Persistence with osteoporosis therapy is important for optimal reduction of fracture risk. Persistence with denosumab was >90% in a randomized clinical trial in women…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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