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  • Abstract Number: 2082 • 2013 ACR/ARHP Annual Meeting

    Interferon-Regulated Chemokine and Innate Cytokine Scores Identify Refractory Myositis Patients That Respond Better To Rtuximab Therapy

    Consuelo Lopez de Padilla1, Cynthia S. Crowson2, Molly S. Hein3, Helen Khun2, Rohit Aggarwal4, Marc C. Levesque5, Dana P. Ascherman6, Chester V. Oddis7 and Ann M. Reed3, 1Rheumatology/Immunology Research, Mayo Clinic, Rochester, MN, 2Department of Health Sciences Research, Mayo Clinic, Rochester, MN, 3Rheumatology, Mayo Clinic, Rochester, MN, 4Medicine / Rheumatology, University of Pittsburgh, Pittsburgh, PA, 5Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 6Medicine/Rheumatology, University of Miami, Miami, FL, 7Rheum/Clinical Immunology, University of Pittsburgh, Pittsburgh, PA

    Background/Purpose: Serum cytokines play an important role in the pathogenesis of myositis by initiating and perpetuating various cellular and humoral autoimmune processes. The aim of…
  • Abstract Number: 2083 • 2013 ACR/ARHP Annual Meeting

    Environmental Factors Associated With Disease Flare In Juvenile and Adult Dermatomyositis

    Gulnara Mamyrova1, Lisa G. Rider2, Olcay Jones3, Alison Ehrlich4, Lauren M. Pachman5, Robert Nickeson6, Lisa G. Criscione-Schreiber7, Frederick W. Miller2, Lawrence K. Jung8 and James D. Katz1, 1Rheumatology, George Washington University, Washington, DC, 2Environmental Autoimmunity Group, NIEHS, NIH, Bethesda, MD, 3Pediatrics, Walter Reed National Military Medical Center, Bethesda, MD, 4Dermatology, The George Washington University, Washington, DC, 5Division of Pediatric Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, 6Pediatrics, All Children's Hospital, St Petersburg, FL, 7Dept of Med/Rheum Div, Duke University School of Medicine, Durham, NC, 8Pediatric Rheumatology, Children's National Medical Center, Washington, DC

    Background/Purpose: To assess environmental factors in relationship to increased disease activity (flare) in juvenile and adult dermatomyositis (DM). Methods: An online survey was conducted for…
  • Abstract Number: 2084 • 2013 ACR/ARHP Annual Meeting

    Increasing Incidence Of Immune Mediated Necrotizing Myopathy In A Single Center

    Martin Klein1, Herman F. Mann2, Josef Zámecník3 and Jiri Vencovsky4, 1Institute of Rheumatology, Prague, Prague, Czech Republic, 2Institute of Rheumatology and Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Prague, Czech Republic, 3Department of Pathology and Molecular Medicine, 2nd Medical School and University Hospital Motol, Charles University, Prague, Czech Republic, Prague, Czech Republic, 4Department of Clinical and Experimental Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Institute of Rheumatology, Prague, Czech Republic

    Background/Purpose: Immune mediated necrotizing myopathy (IMNM), characterized histologically by predominant myofiber necrosis with minimal or no inflammatory infiltrate and clinically by response to immunosuppressive therapy,…
  • Abstract Number: 2085 • 2013 ACR/ARHP Annual Meeting

    Identification Of Clinical Features and Risk Factors Associated With Calcinosis In Adult Patients With Dermatomyositis

    Antonia Valenzuela1, Lorinda Chung2, Livia Casciola-Rosen3, Antony Rosen3 and David Fiorentino4, 1Division of Immunology and Rheumatology, Stanford University School of Medicine, Palo Alto, CA, 2Immunology and Rheumatology, Stanford University School of Medicine, Palo Alto, CA, 3Division of Rheumatology, Johns Hopkins University, Baltimore, MD, 4Dermatology, Stanford University School of Medicine, Redwood City, CA

    Background/Purpose: Prior studies have estimated that 20% of adult dermatomyositis (DM) patients suffer from calcinosis.  Although calcinosis is related to persistent disease activity, poor treatment…
  • Abstract Number: 2086 • 2013 ACR/ARHP Annual Meeting

    Defining The Prevalence and Associated Risk Factors For Calcinosis In Adult Dermatomyositis Patients

    Jessie Werner1, Jason Liebowitz2, Andrew L. Mammen3 and Lisa Christopher-Stine4, 1Medicine, University of Maryland School of Medicine, Baltimore, MD, 2Johns Hopkins University School of Medicine, Baltimore, MD, 3NIAMS, NIH, Bethesda, MD, 4Medicine and Neurology, Johns Hopkins University, Baltimore, MD

    Background/Purpose: Calcinosis is known to be associated with junvenile dermatomyositis, but the prevalence and risk factors associated with the development of calcinosis in adult dermatomyositis…
  • Abstract Number: 2087 • 2013 ACR/ARHP Annual Meeting

    Utility and Reliability Of Digital Nailfold Capillaroscopy In Children With Juvenile Dermatomyositis:  Three Methods

    Gabrielle A. Morgan1, Adam Ostrower1, Chiang-Ching Huang2 and Lauren M. Pachman1,3, 1Cure JM Myositis Center, Ann & Robert H. Lurie Children's Hospital of Chicago Research Center, Chicago, IL, 2Zilber School of Public Health, University of Wisconsin at Milwaukee, Milwaukee, WI, 3Division of Pediatric Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL

    Background/Purpose: Nailfold Capillaroscopy (NFC) is a non-invasive assessment of the nailfold area of the fingers which aids in the diagnosis of Juvenile Dermatomyositis (JDM) by…
  • Abstract Number: 2088 • 2013 ACR/ARHP Annual Meeting

    The Percentage Of Th17 Cells Correlates with the Expression Of Microrna-206 In Patients With Dermatomyositis

    Xinyi Tang1 and Shengjun Wang2, 1Department of Laboratory Medicine, Jiangsu University Affi�liated People’s Hospital, Zhenjiang, China, 2Department of Immunology, Department of Immunology, Jiangsu University, Zhenjiang, China

    Background/Purpose: DM (dermatomyositis) is a subtype of inflammatory myopathies,which is a rare autoimmune disease of skeletal muscle.  Although the pathogenic mechanism of DM is still…
  • Abstract Number: 2049 • 2013 ACR/ARHP Annual Meeting

    Comparison Of Corticosteroid Plus Lidocaine Or Lidocaine Alone In Patients Receiving Celecoxib For The Treatment Of Acute Shoulder Or Trochanteric Bursitis: A Randomized, Double-Blind, Placebo Controlled Trial

    Muhammad Imran1, Haritha Narla2, Jo A. Wick3 and Herbert B. Lindsley4, 1Rheumatology, Kansas University Medical center, Kansas city, MO, 2Rheumatology, Kansas university Medical Center, kansas city, MO, 3Biostatistics, Kansas University Med Ctr, Kansas City, KS, 4Medicine, Kansas University Med Ctr, Kansas City, KS

    Background/Purpose: Bursitis is a self-limiting disorder in the majority of patients and typically responds to conservative measures. However, corticosteroid injections may be necessary in recurrent…
  • Abstract Number: 2050 • 2013 ACR/ARHP Annual Meeting

    Arthralgia Occurring Under Aromatase Inhibitor Treatment For Breast Cancer.  A Prospective Study

    Daniel Wendling1, Helene Letho-Gyselinck1, Xavier Guillot2, Clément Prati3 and Xavier Pivot4, 1Service de Rhumatologie, Minjoz University Hospital, Besancon, France, 2Department of Rheumatology, CHRU Besançon, Besançon, France, 3Service de Rhumatologie, CHU J Minjoz, Besancon, France, 4Oncology, CHRU Besançon, Besançon, France

    Background/Purpose: Treatment with third generation aromatase inhibitors (AI) is associated with occurrence of arthralgia, with an incidence ranging from 25 to 45 %. In these…
  • Abstract Number: 2051 • 2013 ACR/ARHP Annual Meeting

    Characteristics and Comparison Of Patients With Cystic Fibrosis With and Without Arthritis

    Heather O. Tory1, Karen Herlyn2, David Zurakowski3, Angela S. Pizzo4, Robert P. Sundel5 and Peter A. Merkel6, 1Rheumatology Program, Division of Immunology, Boston Children's Hospital, Boston, MA, 2Department of Rheumatology, University Hospital Schleswig-Holstein, Lübeck, Germany, 3Departments of Anesthesia and Surgery, Boston Children’s Hospital, Boston, MA, 4Mercy Hospital, Portland, ME, 5Division of Immunology, Boston Children's Hospital, Boston, MA, 6Division of Rheumatology, Vasculitis Center, University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Cystic Fibrosis (CF) is a common genetic mutation in Caucasian populations. Many patients have musculoskeletal complaints and 12% develop arthritis, including CF arthropathy (CFA),…
  • Abstract Number: 2052 • 2013 ACR/ARHP Annual Meeting

    The Prevalence and Pattern Of Self Reported Joint Symptoms In Cystic Fibrosis

    Carl Orr1, Cormac McCarthy1, Johan Meurling1, Paul G. O'Connell2, Cedric Gunaratnam1,3 and Noel G McElvaney1, 1Department of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland, 2Rheumatology, Beaumont Hospital, Dublin, Ireland, 3Department of Respiratory Medicine, Beaumont Hospital, Dublin, Ireland

    Background/Purpose: Arthritis in cystic fibrosis (CF) can be very incapacitating, and it is mainly of three types: CF arthritis, hypertrophic osteoarthropathy, and arthritis due to…
  • Abstract Number: 2053 • 2013 ACR/ARHP Annual Meeting

    Efficacy Of Intermittent Intra-Venous Cyclophosphamide and Cyclosporin A Combination Therapy For Rapidly Progressive Interstitial Lung Disease With Dermatomyositis Associated With Anti-Melanoma Differentiation-Associated Gene 5 Autoantibody Titer

    Noriko Sasaki1, Shinji Sato1, Shinichi Nogi1, Naofumi Chinen2, Kiri Honda1, Eiko Saito1, Chiho Yamada2 and Yasuo Suzuki2, 1Rheumatology, Tokai University School of Medicine, Isehara, Japan, 2Division of Rheumatology, Department of Internal Medicine, Tokai University School of Medicine, Isehara, Japan

    Background/Purpose: Anti-Melanoma Differentiation-Associated Gene 5 (MDA5) autoantibody is present specifically in patients with dermatomyositis (DM), especially those with few or no muscle manifestations (clinically amyopathic…
  • Abstract Number: 2054 • 2013 ACR/ARHP Annual Meeting

    Efficacy and Safety Of Low-Intensity Resistance Training Combined With Vascular Occlusion In Polymyositis and Dermatomyositis

    Melina Mattar1, Luiz A. Perandini1, Thalita Dassouki2, Samuel K. Shinjo1, Bruno Gualano3, Hamilton Roschel3, Fernanda R. Lima4 and Ana Lucia S. Pinto1, 1University of Sao Paulo, Rheumatology Division, LACRE, Sao Paulo, Brazil, 2Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil, 3University of Sao Paulo, School of Physical Education and Sport, Sao Paulo, Brazil, 4University of Sao Paulo, Rheumatology Division, Sao Paulo, Brazil

    Background/Purpose: Previous studies have demonstrated that low-intensity resistance training combined with vascular occlusion (VO) improves muscle strength to the magnitude of traditional high-intensity resistance training…
  • Abstract Number: 2055 • 2013 ACR/ARHP Annual Meeting

    Killer T Cell Inhibition By CD226 Blockade For Treatment Of Inflammatory Myopathy

    Hitoshi Kohsaka1, Nao Tateishi1, Shinya Hirata2, Kazuko Shibuya3, Akira Shibuya3 and Nobuyuki Miyasaka4, 1Department of Medicine and Rheumatology, Tokyo Medical and Dental University, Tokyo, Japan, 2Department of Rheumatology and Clinical Immunology, Kumamoto University School of Medicine, Kumamoto, Japan, 3Department of Immunology, University of Tsukuba, Ibaraki, Japan, 4Tokyo Medical and Dental University, Tokyo, Japan

    Background/Purpose: Current treatment strategy of polymyositis/dermatomyositis calls for administration of high dose glucocorticoids and additional immunosupressants when necessary. These options are based largely on successful…
  • Abstract Number: 2056 • 2013 ACR/ARHP Annual Meeting

    Use Of Biologics In Polymyositis and Dermatomyositis – A National Register Study

    John Svensson1, Anna Tjärnlund2, Balsam Hanna3, Sara Magnusson Bucher4, Johan Askling5, Ingrid E. Lundberg6 and Maryam Dastmalchi7, 1Department of Medicine, Rheumatology Unit, Karolinska Institutet, Stockholm, Sweden, 2Rheumatology Unit, Department of Medicine, Karolinska University Hospital, Solna, Karolinska Institutet, Stockholm, Stockholm, Sweden, 3Rheumatology Unit, Sahlgrenska University Hospital, Gothenburg, Sweden, 4Rheumatology unit, Örebro University Hospital, Örebro, Sweden, 5Karolinska Institutet, Stockholm, Sweden, 6Rheumatology Unit, Karolinska University Hospital, Solna, Karolinska Institutet, Stockholm, Sweden, 7Rheumatology Unit, Department of Medicine, Karolinska University Hospital in Solna, Karolinska Institutet, Stockholm, Sweden

    Background/Purpose: Biologics have been used off-label in treatment of refractory polymyositis (PM) and dermatomyositis (DM). In this study we aimed to describe the use of…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

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