Abstracts Archive - Page 2295 of 2425 - ACR Meeting Abstracts

Abstract Number: 1908 • 2012 ACR/ARHP Annual Meeting
Multinational Evidence-Based Recommendations for Diagnosis and Management of Gout: Integrating Systematic Literature Research and Expert Opinion of a Broad Panel of Rheumatologists in the 3E Initiative
Mariano Andres¹, Francisca Sivera², Alison Kydd³, John Moi⁴, Rakhi Seth⁵, Melonie K. Sriranganathan⁶, Caroline van Durme⁷, Irene AAM van Echteld⁸, Ophir Vinik⁹, Mihir D. Wechalekar¹⁰, Daniel Aletaha¹¹, Claire Bombardier⁹, Rachelle Buchbinder¹², Loreto Carmona¹³, Christopher J. Edwards¹⁴, R. Landewe¹⁵ and Désirée van der Heijde¹⁶, ¹Seccion Reumatologia, Hospital General Universitario de Alicante, Alicante, Spain, ²Sección de Reumatología, Hospital General Universitario de Elda, Alicante, Spain, ³Division of Rheumatology, University of British Columbia, Vancouver, BC, Canada, ⁴Royal Melbourne Hospital, Melbourne, Australia, ⁵Rheumatology, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom, ⁶Rheumatology, St. Mary's Hospital, Isle of Wight, United Kingdom, ⁷Maastricht University Medical Centre, Maastricht, Netherlands, ⁸Atrium Medical Center, Heerlen, Netherlands, ⁹Rheumatology, University of Toronto, Toronto, ON, Canada, ¹⁰Flinders University School of Medicine, Adelaide, Australia, ¹¹Department of Internal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, ¹²Monash Department of Clinical Epidemiology at Cabrini Hospital, Department of Epidemiology and Preventive Medicine, Monash University, Malvern, Victoria, Australia, ¹³Health Sciences School, Universidad Camilo José Cela, Villanueva de la Cañada, Spain, ¹⁴NIHR Wellcome Trust Clinical Research Facility, University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom, ¹⁵Division of Clinical Immunology and Rheumatology, Academic Medical Center / University of Amsterdam, Amsterdam, Netherlands, ¹⁶Rheumatology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: The 3e (Evidence, Expertise, Exchange) Initiative is a multinational collaboration that aims to promote evidence-based medicine in rheumatology. The 2011-12 3e Initiative aimed to…
Abstract Number: 1909 • 2012 ACR/ARHP Annual Meeting
Use of Uric Lowering Therapies within a Large Health Care System
Robert A. Overman¹, Brian F. Mandell² and Chad L. Deal³, ¹Rheumatology, Cleveland Clinic Foundation, Cleveland, OH, ²Dept of Rheum/Immun NA10, The Cleveland Clinic, Cleveland, OH, ³Dept of Rheum & Imm Dis /A 50, Cleveland Clinic, Cleveland, OH
Background/Purpose: Guidelines for initiating urate lowering therapy (ULT) in the treatment of gout recommend treatment to a target serum urate (SUA) level of ≤6mg/dl with…
Abstract Number: 1910 • 2012 ACR/ARHP Annual Meeting
Regulation of Microrna 223 Expression in a Gouty Arthritis
Gianina Statache¹, Ashleigh-Ann Rainey¹, Seth Masters², Andra Balanescu³, Iain B. McInnes⁴ and Mariola Kurowska-Stolarska⁵, ¹Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom, ²Immunology Research Centre, Trinity College Dublin, Dublin, United Kingdom, ³Internal Medicine and Rheumatology, University of Medicine and Pharmacy, Bucharest, Romania, ⁴University of Glasgow, Glasgow, United Kingdom, ⁵Institute of Infection,Immunity and Inflammation, University of Glasgow, Glasgow, United Kingdom
Background/Purpose: Gout is an inflammatory chronic disease caused by deposition of uric acid crystals in the joint and connective tissues causing pain and disability. Current…
Abstract Number: 1911 • 2012 ACR/ARHP Annual Meeting
Efficacy and Safety of Canakinumab Vs Triamcinolone Acetonide in Patients with Gouty Arthritis Unable to Use Nonsteroidal Anti-Inflammatory Drugs and Colchicine, and On Stable Urate Lowering Therapy (ULT) or Unable to Use ULT
T. Bardin¹, A. So², R. Alten³, M. Bloch⁴, M. R. John⁵, G. Krammer⁵, J. M. Nebesky⁵, A. Tao⁶ and N. Schlesinger⁷, ¹Service de Rhumatologie, Hôpital Lariboisière, Paris, France, ²Centre Hospitalier Universitaire Vaudois, University of Lausanne, Lausanne, Switzerland, ³Charité Univ Medicine, Berlin, Germany, ⁴Holdsworth House Medical Practice, Sydney, Australia, ⁵Novartis Pharma AG, Basel, Switzerland, ⁶Novartis Pharmaceuticals Corporation, East Hanover, NJ, ⁷UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ
Background/Purpose: The primary treatment goals for gouty arthritis (GA) are rapid relief of pain and inflammation during acute attacks, and long-term hyperuricemia management. A post-hoc…
Abstract Number: 1912 • 2012 ACR/ARHP Annual Meeting
Colchicine, As Assessed by Target Joint Pain Scores, Is Effective At 16 Hours in Patients with Acute Gout Flares
Suman Wason¹, Thomas Lauterio¹, Steve Crockett¹ and Matthew W. Davis², ¹Clinical Development, URL Pharma, Philadelphia, PA, ²Clinical Pharmacology, URL Pharma, Philadelphia, PA
Background/Purpose: The management of patients with gout remains suboptimal, leading to increasing frequency and severity of recurrent flares that eventually lead to joint destruction and…
Abstract Number: 1913 • 2012 ACR/ARHP Annual Meeting
Complete Tophus Response in Patients with Chronic Gout Initiating Pegloticase Treatment
Michael A. Becker¹, Neil J. Gonter², Janet E. Pope³, Raymond L. Malamet⁴ and Herbert S. B. Baraf⁵, ¹Medicine, University of Chicago, Chicago, IL, ²Rheumatology Associates of North Jersey, Teaneck, NJ, ³Medicine/Rheumatology, St. Joseph Health Care London, University of Western Ontario, London, ON, Canada, ⁴Global Medical Affairs, Savient Pharmaceuticals, Inc., Bridgewater, NJ, ⁵Arthritis & Rheumatism Associates, Wheaton, MD
Background/Purpose: Pegloticase, a recombinant modified mammalian uricase that acts via enzymatic degradation of uric acid to allantoin, is approved in the US for the treatment…
Abstract Number: 1914 • 2012 ACR/ARHP Annual Meeting
The Diagnosis and Management of Gout in 2012: Survey of US and Canadian Rheumatologists
John J. Cush¹ and Robert T. Keenan², ¹Baylor Research Institute, Dallas, TX, ²Rheumatology, Duke University, Durham, NC
Background/Purpose: The introduction of novel treatment modalities for gout has escalated interest and education on this topic. Although gout is the most common inflammatory arthropathy…
Abstract Number: 1915 • 2012 ACR/ARHP Annual Meeting
Elevated Serum Homocysteine Levels Were Related Not with Serum Uric Acid Levels but with Decreased Renal Function in Chronic Gouty Patients
Sang Tae Choi¹, Jung-Soo Song¹, Jin Su Kim², Eun-Jin Kang³, Kwang-Hoon Lee⁴ and You-Jung Ha⁵, ¹Rheumatology, Chung-Ang University College of Medicine, Seoul, South Korea, ²Chung-Ang University College of Medicine, Seoul, South Korea, ³Rheumatology, Busan Medical Center, Busan, South Korea, ⁴Dongguk University Ilsan Hospital, Goyang, South Korea, ⁵Kwandong University college of Medicine, Goyang, South Korea
Background/Purpose: Hyperhomocysteinemia, which is related with cardiovascular diseases and metabolic syndrome, is regarded as one of the important factors in endothelial cell damage processes. It…
Abstract Number: 1916 • 2012 ACR/ARHP Annual Meeting
Serum Uric Acid As a Biomarker for Mitigation of Infusion Reactions in Patients Treated with Pegloticase for Refractory Chronic Gout
Herbert S. B. Baraf¹, Robert A. Yood², John S. Sundy³, Faith D. Ottery⁴ and Michael A. Becker⁵, ¹Arthritis & Rheumatism Associates, Wheaton, MD, ²Reliant Medical Group, Worcester, MA, ³Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, ⁴Medical Affairs, Savient Pharmaceuticals, Inc., East Brunswick, NJ, ⁵Medicine, University of Chicago, Chicago, IL
Background/Purpose: Using data pooled from the randomized, placebo-controlled trials (RCTs) of pegloticase, post-hoc analyses of urate-lowering, antibody titers and the patterns of infusion-related reactions (IRs)…
Abstract Number: 1917 • 2012 ACR/ARHP Annual Meeting
Long-Term Follow-up of IgG4-Related Diseases Presenting with Lacrimal and Salivary Gland Involvement
Hiroki Takahashi¹, Motohisa Yamamoto¹, Tetsuya Tabeya¹, Chisako Suzuki¹, Yasuyoshi Naishiro¹, Yasuhisa Shinomura¹ and Kohzoh Imai², ¹First Department of Internal Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan, ²The Institute of Medical Science, The University of Tokyo, Tokyo, Japan
Background/Purpose: IgG4-related disease (IgG4-RD) is a recently recognized disease entity that is characterized by tumefactive and hyperplastic lesions in various organs including the lacrimal and…
Abstract Number: 1918 • 2012 ACR/ARHP Annual Meeting
Cluster Analysis of Organ Involvements Patients with Serum IgG4 Elevation; IgG4–related Disease Is a Distinct Subtype of Patients with Hyper-IgG4
Masamitsu Tatewaki, Kazuhiro Kurasawa, Ayae Tanaka, Junya Nagasawa, Satoko Arai, Reika Maezawa, Takayoshi Owada and Takeshi Fukuda, Clinical Immunology, Dokkyo Medical University, Mibu, Tochigi, Japan
Background/Purpose: IgG4-related disease (IgG4-RD) is a multi-organ affecting disease characterized by fibroinflammatory lesions with a abundant IgG4-positive plasma cells infiltration. This disorder includes many…
Abstract Number: 1879 • 2012 ACR/ARHP Annual Meeting
Work Related Injuries Causing or Aggravating Fibromyalgia in the Medicolegal Arena: A Jurisprudential Analysis
Mary-Ann Fitzcharles¹, Peter A. Ste-Marie² and Yoram Shir³, ¹Rheumatology and Pain Management Unit, McGill University Health Centre, Montreal, QC, Canada, ²University of Montreal, Montreal, QC, Canada, ³Alan Edwards Pain Management Unit, McGill University Health Centre, Montreal, QC, Canada
Background/Purpose: Up to 40% of persons report onset of fibromyalgia (FM) following a “triggering event”. Injuries, which may occur in the workplace, may be implicated…
Abstract Number: 1880 • 2012 ACR/ARHP Annual Meeting
A Brazilian Portuguese Validation of the Revised Fibromyalgia Impact Questionnaire (FIQR)
Eduardo S. Paiva¹, Roberto E. Heymann², Marcelo C. Rezende³, Milton Helfenstein Jr.⁴, José E. Martinez⁵, José R. Provenza⁶, Aline Ranzolin⁷, Marcos Renato Assis⁸, Vivian D. Pasqualin⁹ and Robert M. Bennett¹⁰, ¹Rheumatology, Universidade Federal do Paraná, Curitiba, Brazil, ²Rheumatology, Universidade Federal de São Paulo, São Paulo, Brazil, ³Rheumatology, Santa Casa de Campo Grande, Campo Grande, Brazil, ⁴Rheumatology, Universidade Federal de de São Paulo, São Paulo, Brazil, ⁵Rheumatology, Pontifícia Universidade Católica de São Paulo, Sorocaba, Brazil, ⁶Rheumatology, Pontifícia Universidade Católica de Campinas, Campinas, Brazil, ⁷Universidade Federal de Pernambuco, Recife PE, Brazil, ⁸Faculdade de Medicina de Marilia, Marilia, Brazil, ⁹Pontifícia Universidade Católica do Paraná, Curitiba, Brazil, ¹⁰Medicine & Nursing, Oregon Health & Science Univ, Portland, OR
Background/Purpose: General health evaluation questionnaires are important instruments in assessing the impact of disorders that affect multiple domains of a patient´s life. The Fibromyalgia Impact Questionnaire…
Abstract Number: 1881 • 2012 ACR/ARHP Annual Meeting
Increased Psychosocial Stress Is a Major Component of Fibromyalgia Triggers
Emma K. Guymer¹, Kathleen Elford² and Geoffrey O. Littlejohn³, ¹Rheumatology and Medicine, Monash Medical Centre and Monash University, Clayton, Victoria, Australia, ²Rheumatology, Monash Medical Centre, Clayton, Victoria, Australia, ³Rheumatology, Monash Medical Centre and Monash University, Clayton, VIC, Australia
Background/Purpose: Fibromyalgia is a common, chronic pain disorder. Initial development of symptoms occurs under conditions unique to each patient. Psychological and physical triggers are recognized,…
Abstract Number: 1882 • 2012 ACR/ARHP Annual Meeting
Predictors of a Favorable Outcome in Patients with Fibromyalgia: Results From the 1-Year Follow-up
Dong-Jin Park¹, Shin-Seok Lee², Seong-Ho Kim³, Seong-Su Nah⁴, Ji Hyun Lee⁵, Seong-Kyu Kim⁶, Yeon-Ah Lee⁷, Seung-Jae Hong⁷, Hyun-Sook Kim⁸, Hye-Soon Lee⁹, Hyoun Ah Kim¹⁰, Chung-Il Joung¹¹ and Sang-Hyon Kim¹², ¹Rheumatology, Chonnam National University Medical School, Gwangju, South Korea, ²Dept of Int Med/Rheumatology, Chonnam National University Medical School, Gwangju, South Korea, ³Department of Internal Medicine,, Inje University Haeundae Paik Hospital, Busan, South Korea, ⁴Rheumatology, Soonchunhyang University, South Korea, ⁵Division of Rheumatology, Department of Internal Medicine, Maryknoll Medical Center, Busan, South Korea, ⁶Catholic University of Daegu School of Medicine, Daegu, South Korea, ⁷Division of Rheumatology, Department of Internal Medicine, Kyung Hee University, Seoul, South Korea, ⁸Internal Medicine, Chosun University Hospital, Gwangju, South Korea, ⁹Department of Rheumatology, Hanyang University Guri Hospital, Guri, South Korea, ¹⁰Ajou University Hospital, Suwon, South Korea, ¹¹Department of Internal Medicine, Konyang university hospital, Daejeon, South Korea, ¹²Division of Rheumatology, Department of Internal Medicine, Keimyung University School of Medicine, Daegu, South Korea
Background/Purpose: To determine the outcomes in Korean patients with fibromyalgia (FM) and identify the prognostic factors associated with improvement at 1-year follow-up. Methods: Forty-eight patients…

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