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  • Abstract Number: 2469 • 2013 ACR/ARHP Annual Meeting

    Radiographic Sacroiliitis Progression In An Early Spondyloarthritis Cohort

    Concepcion Castillo-Gallego1, Eugenio de Miguel2, Carmen Martin-Hervas3, Diana Peiteado1, Leticia Lojo4 and Emilio Martin-Mola5, 1Rheumatology, Hospital La Paz - IdiPaz, Madrid, Spain, 2Rheumatology, University Hospital La Paz - IdiPaz, Madrid, Spain, 3Radiology, Hospital Universitario La Paz, Madrid, Spain, 4Rheumatology, Hospital Universitario La Paz, Spain, Spain, 5Rheumatology, Hospital Universitario La Paz, Madrid, Spain

    Background/Purpose:  The improvement of treatment in axial Spondyloarthritis (axSpA) and the development of the ASAS classification criteria have facilitated the early diagnosis and management of…
  • Abstract Number: 2470 • 2013 ACR/ARHP Annual Meeting

    Combined Axial and Peripheral Involvement Is Associated With Miscegenation In A Large and Heterogeneous Brazilian Cohort Of 1505 Patients With Spondyloarthritis

    Percival D Sampaio-Barros1, Mittermayer Santiago2, Adriana B. Bortoluzzo2, Antonio Carlos Ximenes2, José Antonio Braga da Silva2, Manoel B Bértolo2, Sandra Lúcia Ribeiro2, Mauro Keisermann2, Rita Menin2, Thelma L. Skare2, Sueli Carneiro2, Valderilio F. Azevedo2, Walber P. Vieira2, Elisa Albuquerque2, Washington A. Bianchi2, Rubens Bonfiglioli2, Cristiano Campanholo2, Hellen M Carvalho2, Izaias P. Costa2, Angela Luzia B. P. Duarte2, Charles Kohem2, Nocy Leite2, Sonia Lima2, Eduardo S. Meirelles2, Ivânio A. Pereira2, Marcelo M. Pinheiro2, Elizandra Polito2, Gustavo G. Resende2, Francisco AC Rocha3, Maria de Fátima L. C. Sauma2, Valéria Valim2 and Celio R. Gonçalves2, 1Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 2Brazilian Registry of Spondyloarthritis, São Paulo, Brazil, 3Rheumatology, Brazilian Registry of Spondyloarthritis, São Paulo, Brazil

    Background/Purpose: Spondyloarthritides (SpA) constitute a group of diseases that can present different patterns according to the genetic background. Brazilis a large country with a heterogeneous…
  • Abstract Number: 2443 • 2013 ACR/ARHP Annual Meeting

    Prevalence Of Coronary Heart Disease In Spondyloarthopathies  may Be Increased Due To Higher Prevalence Of Risk Factors As Well As The Disease Itself- A Retrospective Analysis At Single VA Medical Center

    Trayton Mains1 and Vikas Majithia2, 1University of Mississippi Medical Center, Jackson, MS, 2G.V. "Sonny" Montogomery VA Medical Center, Jackson, MS

    Background/Purpose: An increased prevalence of cardiovascular disease (CVD) and coronary heart disease (CHD) has been reported in patients with spondyloarthritides (SpA). This study investigated the…
  • Abstract Number: 2431 • 2013 ACR/ARHP Annual Meeting

    Association Of T Follicular Helper / Th17 T Cell and Memory B Cell Populations In Rheumatoid Arthritis With Disease Activity and Therapy With TNF Antagonists

    Marc C. Levesque1, Camilla Macedo2, Lisa Boyette2, Kevin Hadi3, Erich R Wilkerson4, Diana Metes2, Larry W. Moreland5 and Mandy J. McGeachy6, 1Division of Rheumatology and Clinical Immunology, University of Pittsburgh Department of Medicine, Pittsburgh, PA, 2University of Pittsburgh, Pittsburgh, PA, 3Univeristy of Pittsburgh, Pittsburgh, PA, 4Medicine, University of Pittsburgh, Pittsburgh, PA, 5Medicine, Division of Rheumatology and Clinical Immunology, University of Pittsburgh, Pittsburgh, PA, 6Medicine, Division of Rheumatology and Clinical Immunology, Univeristy of Pittsburgh, Pittsburgh, PA

    Background/Purpose: Autoreactive memory B cells and T cells contribute to the pathogenesis of rheumatoid arthritis (RA) through production of antibodies and cytokines that activate monocytes…
  • Abstract Number: 2432 • 2013 ACR/ARHP Annual Meeting

    Characterization Of Lung Inflammation and Identification Of Shared Citrullinated Targets In The Lungs and Joints Of Early RA

    Vijay Joshua1, Gudrun Reynisdottir2, Jimmy Ytterberg1, Marianne Engström2, Anders Eklund3, Magnus Skold3, Per-Johan Jakobsson4, Johan Rönnelid5, Vivianne Malmström6, Lars Klareskog4, Johan Grunewald3 and Anca I Catrina4, 1Medicine, Rheumatology Unit, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden, 2Department of Medicine, Rheumatology unit, Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden, 3Department of Medicine, Division of Respiratory Medicine, Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden, 4Medicine, Rheumatology unit, Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden, 5Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden, 6Rheumatology Unit, Department of Medicine, Karolinska University Hospital, Solna, Karolinska Institutet, Stockholm, Sweden

    Background/Purpose: To investigate if lung changes are present in rheumatoid arthritis (RA) patients early in the disease process and to address the contribution of these…
  • Abstract Number: 2433 • 2013 ACR/ARHP Annual Meeting

    Evaluation Of The Two-Step Referral Strategy For Axial Spondyloarthritis In The Spondyloarthritis Caught Early Cohort

    Ozair Abawi1, Rosaline van den Berg1, Désirée van der Heijde2, Manouk de Hooge1, Pauline Bakker1, Monique Reijnierse3, Tom Huizinga1, Jürgen Braun4 and Floris van Gaalen1, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 3Radiology, Leiden University Medical Center, Leiden, Netherlands, 4Rheumazentrum Ruhrgebiet, Herne, Germany

    Background/Purpose: Currently, in primary care no satisfactory referral model exists for referral to the rheumatologist of patients with chronic back pain (CBP) with possible axial…
  • Abstract Number: 2434 • 2013 ACR/ARHP Annual Meeting

    Syndesmophyte Distribution Along The Vertebral Rim In Ankylosing Spondylitis Is Non-Random

    Sovira Tan1, Abhijit Dasgupta1, Jianhua Yao2, John A. Flynn3, Lawrence Yao2 and Michael M. Ward4, 1NIAMS/NIH, Bethesda, MD, 2Diagnostic Radiology, NIH Clinical Center, Bethesda, MD, 3Dept of Medicine, Johns Hopkins University, Baltimore, MD, 4Bldg 10 CRC Rm 4-1339, NIAMS/NIH, Bethesda, MD

    Background/Purpose: Syndesmophytes, the hallmark of structural damage in ankylosing spondylitis (AS), are typically visualized 2-dimensionally by radiographs. However, these projections only allow a limited view…
  • Abstract Number: 2435 • 2013 ACR/ARHP Annual Meeting

    Prevalence Of Inflammatory Lesions MRI-Spine In Patients With Chronic Back Pain Of ≤2 Years Duration Included In The SPACE-Cohort

    Manouk de Hooge1, Rosaline van den Berg2, Monique Reijnierse3, Victoria Navarro-Compán2, Floris van Gaalen2, Karen Fagerli4, Maureen C. Turina5, Maikel van Oosterhout6, Roberta Ramonda7, Tom Huizinga2 and Désirée van der Heijde8, 1Leiden University Medical Center, Leiden, Netherlands, 2Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 3Radiology, Leiden University Medical Center, Leiden, Netherlands, 4Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 5Department of Clinical Immunology and Rheumatology, Academic Medical Center/University of Amsterdam, Amsterdam, Netherlands, 6Rheumatology, GHZ Hospital, Gouda, Netherlands, 7Rheumatology Unit, University of Padova, Padova, Italy, 8Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: Inflammatory lesions of the spine are not included in the ASAS definition of a positive MRI for fulfilment of the ASAS axial spondyloarthritis (axSpA)…
  • Abstract Number: 2436 • 2013 ACR/ARHP Annual Meeting

    Classification Of Axspa Based On Positive Imaging (Radiographs and/or MRI of the Sacroiliac Joints) By Local Rheumatologists Or Radiologists Versus Central Trained Readers In The DESIR-Cohort

    Rosaline van den Berg1, Grégory Lenczner2, Fabrice Thévenin3, Pascal Claudepierre4, Antoine Feydy3, Monique Reijnierse5, Alain Saraux6 and Désirée van der Heijde1, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Radiology, Henri Mondor Teaching Hospital, AP-HP, Créteil, France, 3Radiology B, Paris Descartes University, Côchin Hospital, APHP, Paris, France, 4Rheumatology, Henri Mondor Teaching Hospital, AP-HP, Créteil, France, 5Radiology, Leiden University Medical Center, Leiden, Netherlands, 6Department of rheumatology and unit of immunology (EA 2216), Université Brest Occidentale, Brest, France

    Background/Purpose: Sacroiliitis on MRI and X-rays play an important role in the ASAS axial spondyloarthritis (axSpA) criteria1. Though, recognition of sacroiliitis on X-rays (X-SI) and…
  • Abstract Number: 2437 • 2013 ACR/ARHP Annual Meeting

    Prevalence Of Axial Spondyloarthritis In The United States Among Patients With Chronic Back Pain and Other Spondyloarthritis-Related Features

    Atul A. Deodhar1, Philip J. Mease2, Jeffrey R. Curtis3, Piyalal M. Karunaratne4, Kailash Malhotra4 and Aileen L. Pangan4, 1Oregon Health & Science University, Portland, OR, 2University of Washington and Swedish Medical Center, Seattle, WA, 3University of Alabama at Birmingham, Birmingham, AL, 4AbbVie Inc., North Chicago, IL

    Background/Purpose: The age-adjusted prevalence of spondyloarthritis (SpA) has been estimated to be 0.9-1.4% of the US population using the Amor and ESSG criteria. The objective…
  • Abstract Number: 2438 • 2013 ACR/ARHP Annual Meeting

    Effectiveness Of Exercise Program  in Ankylosing Spondylitis: Meta-Analysis Of Randomized Controlled Trials

    Virginie Pécourneau1, Arnaud L. Constantin2 and Alain G. Cantagrel3, 1CHU Toulouse, Toulouse, France, 2Rheumatology, Purpan University Hospital, Toulouse Cedex 9, France, 3Dept of Rheumatology, Hopital Purpan, Toulouse CEDEX 9, France

    Effectiveness of exercise programs in ankylosing spondylitis: meta-analysis of randomized controlled trialsVirginie Pécourneau1, Adeline Ruyssen-Witrand1, Thomas Barnetche2, Alain Cantagrel1, Arnaud Constantin1.1 Centre de Rhumatologie, HÃxpital…
  • Abstract Number: 2439 • 2013 ACR/ARHP Annual Meeting

    Smoking Was Not Associated With Response To Adalimumab Therapy In Patients With Non-Radiographic Axial Spondyloarthritis

    Joachim Sieper1, Denis Poddubnyy2, Aileen L. Pangan3, Suchitrita S. Rathmann3 and Jaclyn K. Anderson3, 1Charité University Medicine Berlin, Berlin, Germany, 2Charité Universitätsmedizin Berlin, Berlin, Germany, 3AbbVie Inc., North Chicago, IL

    Background/Purpose: Cigarette smoking has been reported as a risk factor for early disease onset, higher disease activity, and poor function in patients (pts) with axial…
  • Abstract Number: 2440 • 2013 ACR/ARHP Annual Meeting

    Is There a Role For Etoricoxib In Patients With Axial Ankylosing spondylitis  Refractory To Traditional NSAID?

    Maria García Manrique1, Pilar Font2, Joan Calvet3, María Cruz Fernandez4, Carlos Montilla5, Luis Linares6, Elia Brito7, Xavier Juanola8, Juan Mulero9, Rubén Queiro10, Rosa M. Morla11, Rosario Garcia-Vicuña12, Alba Erra13, Mireia Moreno14, Marta Larrosa15, Eduardo Collantes16 and Jordi Gratacos17, 1Rheumatology, Hospital Parc Taulí, Sabadell, Spain, 2Rheumatology Unit, IMIBIC-Reina Sofia University Hospital, Cordoba, Spain, 3Rheumatology, Corporació Sanitària Parc Taulí, Sabadell, Spain, 4Rheumatology, Hospital General de Móstoles, Mostoles, Spain, 5Rheumatology Service, Hospital Universitario de Salamanca, Salamanca, Spain, 6Rheumatology, Hospital Universitario Virgen de la Arrixaca, Murcia, Spain, 7Rheumatology, Hospital Ramón y Cajal, Madrid, Spain, 8Rheumatology, University Hospital Bellvitge, Barcelona, Spain, 9Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda (Madrid), Spain, 10Rheumatology Department. Hospital Universitario Central de Asturias, Oviedo, Spain, 11Rheumatology, Hospital Sta Tecla, Tarragona, Spain, 12Rheumatology, Hospital Universitario de La Princesa. IIS La Princesa, Madrid, Spain, 13Hospital de Sant Rafael, Barcelona, Spain, 14Rheumatology, Hospital Universitari Parc Taulí, Sabadell, Spain, 15Rheumatology, Hospital Universitari Parc Tauli, Sabadell, Spain, 16Rheumatology, Hospital Reina Sofia, Cordoba, Spain, 17Rheumatology Service, Hospital Universitari Parc Taulí, Sabadell (Barcelona), Spain

    Background/Purpose: Anti-TNF treatment has demonstrated its effectiveness in axial ankylosing spondylitis (AS) patients with inadecuate response to traditional NSAIDs (tNSAIDs) therapy (>=2 tNSAIDs), but also aspects…
  • Abstract Number: 2441 • 2013 ACR/ARHP Annual Meeting

    Do Postural Deformities In Patients With Ankylosing Spondylitis Cause Balance Problems?

    M. Ece Cinar1, Yesim Akkoc1, Hale Karapolat1 and Gokhan Keser2, 1Department of Physical Medicine and Rehabilitation, Ege University School of Medicine, Izmir, Turkey, 2Dept. of Internal Medicine, Division of Rheumatology, Ege University School of Medicine, Izmir, Turkey

    Background/Purpose: In this study, we assessed the impact of postural deformities caused by ankylosing spondylitis (AS) on balance. Methods: 29 AS patients and 21 healthy…
  • Abstract Number: 2442 • 2013 ACR/ARHP Annual Meeting

    [18F]-Fluoride PET/CT Assessment In Patients Responding To The ASAS Criteria For Spondyloarthritis Despite Negative Sacroiliac Joint MRI

    Cecile Caoduro1, Orland Angoue2, Hatem Boulahdour2 and Eric Toussirot3, 1Nuclear Medicine, University Hospital, Besançon, France, 2Nuclear medicine, University Hospital, Besançon, France, 3Université de Franche Comté , CHRU, CIC Biotherapy 506 and Rheumatology and EA 4266 Pathogens and Inflammation, Besançon, France

    Background/Purpose: The ASAS group has defined criteria for the diagnosis of axial or peripheral spondyloarthritis (SpA). Sacroiliac joint MRI is included in these criteria and…
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