Abstracts Archive - Page 2248 of 2607 - ACR Meeting Abstracts

Abstract Number: 2784 • 2013 ACR/ARHP Annual Meeting
Mononeuritis Multiplex Predicts The Need For Immunosuppressive Or Immunomodulatory Drugs For Eosinophilic Granulomatosis With Polyangiitis, Polyarteritis Nodosa and Microscopic Polyangiitis Patients Without Poor-Prognosis Factors
Maxime Samson¹, Xavier Puéchal², Hervé Devilliers³, Camillo Ribi⁴, Pascal Cohen⁵, Boris Bienvenu⁶, Christian Pagnoux⁷, Luc Mouthon², Loic Guillevin⁸ and French Vasculitis Study Group (FVSG)², ¹Department of Internal Medicine, Referral Center for Rare Autoimmune and Systemic Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France; Internal Medicine and Clinical Immunology, Dijon University Hospital, Dijon, France, ²Department of Internal Medicine, Referral Center for Rare Autoimmune and Systemic Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France, Paris, France, ³Dijon University Hospital, Department of internal medicine and systemic diseases, Dijon, France, ⁴Immunology and Allergology, Internal Medicine, University Hospitals of Geneva, Geneva, Switzerland, Geneva, Switzerland, ⁵National Referral Center for Rare Systemic Autoimmune Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, Paris, France, ⁶Division of Internal Medicine, Centre Hospitalier Régional Universitaire de Caen, Côte de Nacre, Caen, France, Caen, France, ⁷Rheumatology, Mount Sinai Hospital, Toronto, Canada, Toronto, ON, Canada, ⁸Department of Internal Medicine,, Referral Center for Rare Autoimmune and Systemic Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France
Background/Purpose: Patients with eosinophilic granulomatosis with polyangiitis (EGPA), polyarteritis nodosa (PAN) or microscopic polyangiitis (MPA) without poor-prognosis factors, as defined by their 1996 Five-Factor Scores…
Abstract Number: 2785 • 2013 ACR/ARHP Annual Meeting
Urinary Inflammatory Cells Strongly Reflect the Disease Activity and Renal Function in Antineutrophil Cytoplasmic Autoantibody-Associated Vasculitis
Yoko Wada¹, Minoru Sakatsume², Masaaki Nakano³ and Ichiei Narita¹, ¹Division of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan, ²Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan, ³School of Health Sciences, Faculty of Medicine, Niigata University, Niigata, Japan
Background/Purpose: The antineutrophil cytoplasmic autoantibody (ANCA)- associated vasculitides (AAVs) include microscopic polyangiitis (MPA), granulomatosis with polyangitis (GPA; formerly Wegener’s), and eosinophilic granulomatosis with polyangitis (EGPA).…
Abstract Number: 2786 • 2013 ACR/ARHP Annual Meeting
Review Of The Expert Panel Methodology In The Diagnostic and Classification Criteria For Vasculitis Study: A Pilot Study
Cristina Ponte¹, Anthea Craven², Joanna Robson², Peter C. Grayson³, Ravi Suppiah⁴, Richard A. Watts⁵, Peter A. Merkel⁶ and Raashid A. Luqmani², ¹Rheumatology and Metabolic Bone Diseases Department, Hospital de Santa Maria, CHLN and Rheumatology Research Unit, Instituto de Medicina Molecular, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal, ²Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences, Botnar Research Centre, University of Oxford, Oxford, United Kingdom, ³Section of Rheumatology & the Clinical Epidemiology Unit, Boston University School of Medicine, Vasculitis Center, Boston, MA, ⁴Department of Rheumatology, Auckland District Health Board, Auckland, New Zealand, ⁵Rheumatology Department Ipswich Hospital and University of East Anglia, Ipswich, United Kingdom, ⁶Division of Rheumatology, Vasculitis Center, University of Pennsylvania, Philadelphia, PA
Background/Purpose: The Diagnostic and Classification Criteria for Vasculitis (DCVAS) Study is a multinational observational study to develop diagnostic criteria and to update classification criteria for…
Abstract Number: 2787 • 2013 ACR/ARHP Annual Meeting
The Effect Of Smoking On The Clinical Expression Of ANCA-Associated Vasculitis
Neil Basu¹, Aladdin Mohammad², Richard A. Watts³, Paul Gatenby⁴, Luis F. Flores-Suarez⁵ and Alfred Mahr⁶, ¹Musculoskeletal Research Collaboration (Epidemiology Group), University of Aberdeen, Aberdeen, United Kingdom, ²Department of Rheumatology, Skåne University Hospital, Lund, Sweden, ³Rheumatology Department Ipswich Hospital and University of East Anglia, Ipswich, United Kingdom, ⁴ANU Medical School, The Canberra Hospital, Canberra, Australia, ⁵Primary Systemic Vasculitides Clinic, Instituto Nacional de Enfermedades Respiratorias, Mexico City, Mexico, ⁶Department of Internal Medicine, Hospital Saint-Louis, Paris, France
Background/Purpose: It is well recognized that smoking has immuno-modulatory effects in several chronic inflammatory disorders. For ANCA-associated vasculitis (AAV), which includes granulomatosis with polyangiitis (GPA)…
Abstract Number: 2788 • 2013 ACR/ARHP Annual Meeting
Reliability and Responsivenss Of The Standardized Universal Pain Evaluations For Rheumatology Providers For Children and Youth (SUPER-KIDZ)
Nadia Luca¹, Jennifer N. Stinson², Susanne M. Benseler³, Brian M. Feldman⁴, Dorcas Beaton^5,6 and Ahmed Bayoumi⁷, ¹Pediatric Rheumatology, Hospital for Sick Children, Toronto, ON, Canada, ²Anesthesia and Pain Medicine, Hospital for Sick Children, Toronto, ON, Canada, ³Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ⁴Rheumatology, Hospital for Sick Children, Toronto, ON, Canada, ⁵Research, Mobility Program Clinical Research Unit, Li Ka Shing Knowledge Institute, St. Michaels Hospital, Toronto, ON, Canada, ⁶Scientist, Institute for Work & Health, Toronto, ON, Canada, ⁷General Internal Medicine, Keenan Research Centre of the Li Ka Shing Knowledge Institute of St. Michael's Hospital, Toronto, ON, Canada
Background/Purpose: Pain is the most common symptom in children and youth with juvenile idiopathic arthritis (JIA), however, currently there is no comprehensive validated pain measure…
Abstract Number: 2789 • 2013 ACR/ARHP Annual Meeting
Enhancing Uveitis Screening Compliance In Juvenile Idiopathic Arthritis Patients
Melissa S Oliver¹, Jennifer E. Weiss², Suzanne C. Li³, Kathleen A. Haines², Ginger L. Janow², Esi Morgan DeWitt⁴ and Yukiko Kimura², ¹Pediatrics, UMDNJ New Jersey Medical School, Newark, NJ, ²Pediatric Rheumatology, Joseph M Sanzari Children’s Hospital, Hackensack University Medical Center, Hackensack, NJ, ³Pediatrics, Joseph M Sanzari Children’s Hospital, Hackensack University Medical Center, Hackensack, NJ, ⁴Department of Pediatrics, Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
Background/Purpose: Chronic uveitis is one of the more severe morbidities associated with juvenile idiopathic arthritis (JIA). Risk of developing uveitis, and the frequency of uveitis…
Abstract Number: 2790 • 2013 ACR/ARHP Annual Meeting
The Research In Arthritis In Canadian Children Emphasizing Outcomes (ReACCh Out) Cohort: Are We Achieving Clinically Important Outcomes?
Deborah M. Levy¹, Shirley ML Tse¹, Elizabeth Stringer², Jaime Guzman³, Roberta A. Berard⁴, Karen Watanabe Duffy⁵, Dax Rumsey¹, Mercedes O. Chan³, Rosie Scuccimarri⁶, Adam M. Huber⁷, Lori B. Tucker³, Rae SM Yeung¹, Ciaran M. Duffy⁵, Kiem Oen⁸ and The ReACCh Out Investigators⁹, ¹Rheumatology, The Hospital for Sick Children and University of Toronto, Toronto, ON, Canada, ²Department of Rheumatology, IWK Health Centre, Halifax, NS, Canada, ³Rheumatology, BC Children's Hospital and University of British Columbia, Vancouver, BC, Canada, ⁴Children's Hospital of Western Ontario, London, ON, Canada, ⁵Rheumatology, Children's Hospital of Eastern Ontario and University of Ottawa, Ottawa, ON, Canada, ⁶McGill University, Montreal, QC, Canada, ⁷Dalhousie University, Halifax, NS, Canada, ⁸Pediatrics, Children's Hospital of Winnipeg and University of Manitoba, Winnipeg, MB, Canada, ⁹The Hospital for Sick Children and University of Toronto, Toronto, ON, Canada
Background/Purpose: Recent data suggests that achievement of inactive disease and early disease remission may result in improved outcomes for patients with juvenile idiopathic arthritis (JIA). …
Abstract Number: 2791 • 2013 ACR/ARHP Annual Meeting
Telephone Consultation Usage In a Pediatric Rheumatology Clinic: Considerations In Optimizing Nursing Resources
Julie Lemieux¹, Audrey Tran², Vincent Brienza³ and Roman Jurencak³, ¹Pediatrics, Children's Hospital of Eastern Ontario, Ottawa, ON, Canada, ²University of Western Ontario, London, ON, Canada, ³University of Ottawa, Ottawa, ON, Canada
Background/Purpose: Telephone consultation is essential to the delivery of patient care in the ambulatory care clinics at the Children’s Hospital of Eastern Ontario (CHEO). Our…
Abstract Number: 2792 • 2013 ACR/ARHP Annual Meeting
Pediatric Rheumatology Care and Outcomes Improvement Network Demonstrates Performance Improvement On Juvenile Idiopathic Arthritis Quality Measures
Julia G. Harris^1,2, Esi Morgan DeWitt³, Ronald M. Laxer^4,5, Stacy P. Ardoin⁶, Beth S. Gottlieb⁷, Judyann C. Olson^1,2, Murray H. Passo⁸, Jennifer E. Weiss⁹, Daniel J. Lovell¹⁰, Tzielan C. Lee¹¹, Sheetal S. Vora^12,13, Nancy Griffin¹⁴, Jason A. Stock¹⁵, Lynn M. Darbie¹⁴ and Catherine A. Bingham¹⁶, ¹Medical College of Wisconsin, Milwaukee, WI, ²Children's Hospital of Wisconsin, Milwaukee, WI, ³Department of Pediatrics, Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁴Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ⁵Rheumatology, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada, ⁶Pediatric & Adult Rheumatology, Ohio State University College of Medicine, Columbus, OH, ⁷Pediatric Rheumatology, Cohen Children's Medical Center of New York, New Hyde Park, NY, ⁸Pediatrics, Medical University of South Carolina, Charleston, SC, ⁹Pediatric Rheumatology, Hackensack University Medical Center, Hackensack, NJ, ¹⁰Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ¹¹Pediatric Rheumatology, Stanford University School of Medicine, Stanford, CA, ¹²University of North Carolina Chapel Hill, Chapel Hill, NC, ¹³Levine Children's Hospital and Carolinas Medical Center, Charlotte, NC, ¹⁴James M. Anderson Center for Health Systems Excellence, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ¹⁵Biostatistics & Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ¹⁶Pediatric Rheumatology, Penn State Hershey Children's Hospital, Hershey, PA
Background/Purpose: Pediatric Rheumatology Care and Outcomes Improvement Network (PR-COIN) is a multi-site learning network designed to improve outcomes of juvenile idiopathic arthritis (JIA) care. Teams…
Abstract Number: 2793 • 2013 ACR/ARHP Annual Meeting
Towards Developing a Rheumatology-Specific Transition Of Care Program
Rina Mina¹, Janalee Taylor², Pamela A. Heydt³, Terry M. Moore⁴, Julie V. Ranz⁵, Mary Beth Burns⁶, Paula G. Melson⁷, Abigail Nye⁶, Jill Segerman⁵, Yolanda Farhey⁸, John Houk⁹, Avis Ware⁹, Jennifer L. Huggins⁵ and Lisa Vaughn⁶, ¹Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²William S. Rowe Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³Rheumatology, Childrens Hospital Medical Center, Cincinnati, OH, ⁴Pediatric Rheumatology, Cincinnati Chiildren's Hospital Medical Center, Cincinnati, OH, ⁵Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁶Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁷Rheumatology, Children's Hosp Medical Center, Cincinnati, OH, ⁸University of Cincinnati, Cincinnati, OH, ⁹Immunology, Allergy and Rheumatology, University of Cincinnati, Cincinnati, OH
Background/Purpose: Background: Because of their considerable medical challenges, adolescents and young adults with pediatric-onset rheumatic diseases are often reliant on the health care system, and…
Abstract Number: 2794 • 2013 ACR/ARHP Annual Meeting
Characterisation Of Antigens Driving In Situ Autoantibody Production In Human Lupus Tubulointerstitial Nephritis (TIN)
Andrew Kinloch¹, Scott Henderson¹, Natalya Kaverina², Anthony Chang³, D. James Haddon⁴, Justin Jarrel⁴, Carole Henry Dunand², Patrick C. Wilson⁵, Paul Utz⁴ and Marcus R. Clark⁶, ¹Rheumatology and Knapp Center of Lupus and Immunology Research, University of Chicago, Chicago, IL, ²Rheumatology and Knapp Center for Lupus and Immunology Research, University of Chicago, Chicago, IL, ³Pathology, University of Chicago, Chicago, IL, ⁴Medicine, Stanford University School of Medicine, Stanford, CA, ⁵Rheumatology and Knapp center for Lupus and Immunology Research, University of Chicago, Chicago, IL, ⁶Rheumatology and Knapp Center for Lupus Research, University of Chicago, Chicago, IL
Background/Purpose: We have demonstrated that the degree of tubulointerstitial nephritis (TIN) on diagnostic biopsy predicts progression to renal failure. TIN is associated with tertiary lymphoid…
Abstract Number: 2795 • 2013 ACR/ARHP Annual Meeting
B Cell Derived Cytokines Induce Glomerular Injury in Mice
Alfred Kim¹, Shreeram Akilesh², Jeffrey Miner³ and Andrey Shaw⁴, ¹IM/Div of Rheumatology, Washington Univ School of Med, St. Louis, MO, ²Pathology, University of Washington, Seattle, WA, ³Renal Division, Washington University School of Medicine, Saint Louis, MO, ⁴Pathology & Immunology/HHMI, Washington University School of Medicine, Saint Louis, MO
Background/Purpose: Renal involvment remains the leading cause of mortality for SLE patients, and is associated with proteinuria and foot process effacement. In subsets of LN…
Abstract Number: 2756 • 2013 ACR/ARHP Annual Meeting
Serum Periostin Is Associated With Prevalent Knee Osteoarthritis and Predicts Disease Progression In Women: The Ofely Study
Jean-Charles Rousseau¹, Elisabeth Sornay-Rendu¹, Cindy Bertholon¹, Patrick Garnero² and Roland Chapurlat³, ¹INSERM UMR 1033, Lyon, France, ²INSERM, UMR 1033, Lyon and Cisbio Bioassays, Bagnols/Cèze, France, ³Service de Rhumatologie et Pathologie Osseuse, INSERM UMR 1033 and Université de Lyon, Hôpital Edouard Herriot, Lyon, France
Background/Purpose: Periostin (POSTN) is a secreted vitamin K-dependent (Gla-containing) protein produced by osteoblasts and chondrocytes. The aim of this study was to investigate the relationships…
Abstract Number: 2757 • 2013 ACR/ARHP Annual Meeting
Metabolomics For The Identification Of Urinary Biomarkers In Knee Osteoarthritis Progression
Puja Saxena¹, Richard F. Loeser², Wimal Pathmasiri³, Susan Sumner³, Daniel Beavers⁴, David J. Hunter⁵ and Stephen P. Messier⁶, ¹Department of Internal Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, ²Section Of Molecular Medicine, Wake Forest School of Medicine, Winston-Salem, NC, ³Systems and Translational Sciences, NIH Eastern Regional Comprehensive Metabolomics Resource Core, Research Triangle Park, NC, ⁴Department of Public Health Sciences, Wake Forest University School of Medicine, Winston-Salem, NC, ⁵Rheumatology, Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia, ⁶Department of Health and Exercise Science, Wake Forest University, Winston-Salem, NC
Background/Purpose: Obesity is an important risk factor for knee OA, not only due to effects of excess adipose tissue on joint loading, but also due…
Abstract Number: 2758 • 2013 ACR/ARHP Annual Meeting
Quantifying The Risk Of Incident Type II Diabetes Following Oral Glucocorticoid Therapy In Patients With Rheumatoid Arthritis: Association With Dose and Duration Of Use
William G. Dixon¹, Mohammad Movahedi², Marie-Eve Beauchamp³, David W. Ray⁴ and Michal Abrahamowicz³, ¹The University of Manchester, Manchester, United Kingdom, ²Arthritis Research UK Centre for Epidemiology, The University of Manchester, Manchester, United Kingdom, ³Division of Clinical Epidemiology, McGill University, Montreal, QC, Canada, ⁴Institute of Human Development, Institute of Human Development, The University of Manchester, Manchester, United Kingdom
Background/Purpose: Glucocorticoid (GC) therapy is widely used in patients with rheumatoid arthritis (RA). Its association with incident type II diabetes mellitus (DM) is accepted, but…

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