ACR Meeting Abstracts

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  • Abstract Number: 0354 • ACR Convergence 2023

    Open-label Phase 3 Study of Intravenous Golimumab in Patients with Polyarticular Juvenile Idiopathic Arthritis: Pharmacokinetics, Effectiveness, Safety, and Immunogenicity over 252 Weeks

    Nicolino Ruperto1, Daniel J Lovell2, Sarah Ringold3, Xie L. Xu4, Jocelyn H. Leu3, Edwin Lam3, Yuhua Wang3, Alberto Martini5 and Hermine Brunner6, 1IRCCS Istituto Giannina Gaslini, UOSID Centro Trial, Genova, Italy, 2UC Department of Pediatrics, Cincinnati Children's Hospital, University of Cincinnati, Cincinnati, OH, 3Janssen Research & Development, LLC, Spring House, PA, 4Janssen Research & Development, LLC, San Diego, CA, 5Universita degli Studi di Genova, Dipartimento di Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno-Infantili (DiNOGMI), Genova, Italy, 6Cincinnati Children's Hospital Medical Center, Division of Rheumatology, Cincinnati, OH

    Background/Purpose: The phase 3, Intravenous Golimumab in Pediatric Participants with Active Polyarticular-Course JIA Despite MTX (GO-VIVA) study demonstrated that golimumab (GLM) 80 mg/m2 at Week…
  • Abstract Number: 0395 • ACR Convergence 2023

    Prevalence of Objectively Measured Sleep Disturbance in Rheumatoid Arthritis (RA)

    Patti Katz1, Mary Nakamura2, Sarah Patterson3 and Katie Stone4, 1University of California San Francisco, San Rafael, CA, 2UCSF/SFVAHCS, San Francisco, CA, 3University of California San Francisco, Pacifica, CA, 4University of California San Francisco, San Francisco, CA

    Background/Purpose: Self-reported poor sleep is common in RA, but only a few small studies objectively measuring sleep have been conducted in RA. In general population…
  • Abstract Number: 0379 • ACR Convergence 2023

    Clinical Evolution of Patients Diagnosed of Juvenile Idiopathic Arthritis After the Transitional Care Consultation

    Alba Maria Torrat Noves1, Rebeca Perpiñan Perez2, Jose Ivorra Cortes1, Elena Grau Garcia1, Daniel Ramos Castro1, Pablo Francisco Muñoz Martínez3, Laura Mas Sanchez4, Carmen Riesco Barcena1, Anderson Victor Huaylla Quispe1, Samuel Leal Rodriguez1, Belen Villanueva Mañez1, Iago Alcantara Alvarez1, Isabel Martinez Cordellat1, Luis Gonzalez Puig1, Rosa Negueroles Albuixech1, Jose Eloy Oller Rodriguez1, Elvira Vicens Bernabeu1, Ernesto Tovar Sugrañes1, Marta De la Rubia Navarro4, Hikmat Charia1, Ines Canovas Olmos1, Carmen Najera Herranz1 and Jose Andres Roman Ivorra5, 1Rheumatology Department. HUP La Fe, Valencia, Spain, 2Universidad Catolica de Valencia San Vicente Martir, Valencia, Spain, 3Rheumatology Department. HUP La Fe, Sagunto, Spain, 4Rheumatology Department. HUP La Fe, Valéncia, Spain, 5Hospital Universitari i Politècnic la Fe, Valencia, Spain

    Background/Purpose: Juvenile idiopathic arthritis (JIA) encompasses a group of chronic arthritis that begin in childhood. According to the International League of Associations for Rheumatology (ILAR)…
  • Abstract Number: 0333 • ACR Convergence 2023

    Ankylosing Spondylitis Patient Perspective on Living with Flares and Impact on Quality of Life

    Heather Lapidus Glassner and Elizabeth Luce, MyHealthTeam, San Francisco, CA

    Background/Purpose: Ankylosing spondylitis (AS) leads to symptoms of pain, stiffness, swelling, and fatigue. Patients often report periods of increased symptoms (flares) followed by remission.The purpose…
  • Abstract Number: 0396 • ACR Convergence 2023

    Hydroxychloroquine Is Associated with a Decreased Risk of Non-alcoholic Fatty Liver Disease in Patients with Rheumatoid Arthritis: A Population-based, Cohort Study

    Hsin-Hua Chen1 and DER-YUAN CHEN2, 1Taichung Veterans General Hospital, Taichung, Taiwan, 2Center of Rheumatology, China Medical University Hospital, Taichung, Taiwan

    Background/Purpose: Rheumatoid arthritis (RA) is a systemic autoimmune inflammatory disease characterized by chronic destructive arthritis and extra-articular involvement. Prior studies showed patients with RA had…
  • Abstract Number: 0401 • ACR Convergence 2023

    Resolution of Swollen Joint Count Is an Important Clinical Objective in Early Rheumatoid Arthritis : Analysis of the UCLouvain Brussels ERA Cohort and Comparison with the Remission Composite Index

    Francesco Natalucci1, clement triaille2, Emilie Sapart2, Laura BRICMAN3, Cécile VAN MULLEM2, Charlotte Desmet2, Stéphanie DIERCKX4, Marie DOYEN2, Tatiana Sokolova5, Aleksandra AVRAMOVSKA3 and Patrick Durez2, 1UCLouvain University, Sermoneta, Italy, 2Cliniques Universitaires Saint-Luc – Université catholique de Louvain (UCLouvain) – Institut de Recherche Expérimentale et Clinique (IREC), Rheumatology, Brussels, Belgium, 3Rheumatology, Cliniques Universitaires Saint-Luc – Université catholique de Louvain (UCLouvain) – Institut de Recherche Expérimentale et Clinique (IREC), Brussels, Belgium, 4CHU UCL Namur, Rheumatology, Mont-Godinne, Belgium, Mont Godinne, Belgium, 5Université Catholique de Louvain, Brussels, Belgium

    Background/Purpose: Rheumatoid Arthritis is a chronic autoimmune disease characterized by persistent joint inflammation. According to international guidelines, the treatment target should aim to reach the…
  • Abstract Number: 0405 • ACR Convergence 2023

    Clinical Features of Anti-Th/To Antibodies-positive Systemic Sclerosis Patients: A Single-center Retrospective Study

    Ko Fujii, Motoki Horii, Natsumi Fushida, Tomoyuki Ikeda, Yasuhito Hamaguchi and Takashi Matsushita, Department of Dermatology, Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa Ishikawa, Japan

    Background/Purpose: Anti-Th/To antibodies (Abs) have been reported in patients with systemic sclerosis (SSc). The presence of anti-Th/To Abs is detected in 2-5% of SSc cases…
  • Abstract Number: 0403 • ACR Convergence 2023

    Disease Activity Is Associated with Frailty in Veterans with Rheumatoid Arthritis

    Courtney Loecker1, Bryant England2, Punyasha Roul2, Namrata Singh3, Kaleb Michaud2, Lani Zimmerman4, Myra Schmaderer4, Grant Cannon5, Ted R Mikuls6, Gary Kunkel7, Ariela Orkaby8, Joshua Baker9 and K Wysham10, 1University of Nebraska Medical Center;VA Nebraska-Western Iowa Health Care System, Lincoln, NE, 2University of Nebraska Medical Center, Omaha, NE, 3University of Washington, Bellevue, WA, 4University of Nebraska Medical Center, Lincoln, NE, 5University of Utah and Salt Lake City VA, Salt Lake City, UT, 6Division of Rheumatology and Immunology, University of Nebraska Medical Center, Omaha, NE, 7VA Salt Lake City & University of Utah, Salt Lake City, UT, 8Veterans Affairs Boston Healthcare System & Brigham and Women’s Hospital, Harvard Medical School, Boston, MA; VA Geriatric Research Education and Clinical Center, Boston, MA, 9University of Pennsylvania, Philadelphia, PA, 10VA Puget Sound/University of Washington, Seattle, WA

    Background/Purpose: Frailty, defined as an increased vulnerability to stressors and adverse health outcomes, is an emerging concept in RA. Active RA disease gives rise to…
  • Abstract Number: 0390 • ACR Convergence 2023

    Statins Influence the Relationship Between ATP-binding Cassette Transporter A1 (ABCA1)-mediated Cholesterol Efflux and Coronary Atherosclerosis in Rheumatoid Arthritis

    George Karpouzas1, Bianca Papotti2, Sarah Ormseth3, Marcella Palumbo2, Elizabeth Hernandez3, Maria Pia Adorni4, Francesca Zimetti2, Matthew Budoff1 and Nicoletta Ronda2, 1Harbor-UCLA Medical Center, Torrance, CA, 2University of Parma, Department of Food and Drug, Parma, Italy, 3The Lundquist Institute, Torrance, CA, 4Department of Medicine and Surgery, Unit of Neuroscience, University of Parma, Parma, Italy

    Background/Purpose: Cholesterol efflux capacity (CEC) is the main antiatherogenic function of high-density lipoprotein (HDL). ATP-binding-cassette A1 (ABCA1) membrane transporter initiates cholesterol export from arterial macrophages…
  • Abstract Number: 0370 • ACR Convergence 2023

    Clinical Disease Manifestations Associated with TNF Inhibitor Non-Response in Juvenile Spondyloarthritis

    Melissa Oliver1, Kelly Mosesso2, Pamela F. Weiss3, Robert Colbert4, Matthew Stoll5 and Hemalatha Srinivasalu6, 1Indiana University, Indianapolis, IN, 2Indiana University School of Medicine, Indianapolis, IN, 3Children's Hospital of Philadelphia, Philadelphia, PA, 4NIH/NIAMS, Bethesda, MD, 5University of Alabama at Birmingham, Birmingham, AL, 6Children's National Hospital, Washington, DC

    Background/Purpose: Tumor necrosis factor inhibitors (TNFi) are effective in children with juvenile spondyloarthritis (JSpA) and generally represent the first-line choice for biologic therapy. However, not…
  • Abstract Number: 0408 • ACR Convergence 2023

    The Role of Synovial Biopsy in Evaluating Rheumatoid Arthritis Acitivity in Patients: Findings from a Study of 30 Patients Treated with Adalimumab

    Rui Wu and YIlin Peng, the first affilated hospital of Nanchang University, Nanchang, China

    Background/Purpose: Rheumatoid arthritis(RA)is a chronic autoimmune disease that is characterized by inflammation and destrction of synovial jionts  which result in high disabilty. Treat-to-Target is critical…
  • Abstract Number: 0386 • ACR Convergence 2023

    Functional Disability and Disease Activity Are Affected by Social Determinants of Health in Patients with Rheumatoid Arthritis

    Mohammad Movahedi1, Kangping Cui2, George Tomilnson3, Angela Cesta3, xiuying Li3 and Claire Bombardier4, 1Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada, 2Sunnybrook Hospital, Toronto, ON, Canada, 3University Health Network, Toronto, ON, Canada, 4University of Toronto, Toronto, ON, Canada

    Background/Purpose: The relationship between social determinants of health (SDH) (e.g. income, education, and employment status) and disease outcomes in the RA population is not well…
  • Abstract Number: 0365 • ACR Convergence 2023

    Establishing a Multidisciplinary Registry for Temporomandibular Joint Arthritis in Juvenile Idiopathic Arthritis: Insights into Patient Outcomes and Management Challenges

    Stacey Tarvin1, Amy Rakestraw2, Jessica Lee2, N. Shaun Matthews3, Susan H. Ballinger2 and Christina M. Sparks2, 1Riley Hospital for Children at Indiana University Health, Indianapolis, IN, 2Indiana University School of Medicine, Indianapolis, IN, 3Indiana University School of Dentistry, Indianapolis, IN

    Background/Purpose: Temporomandibular joint (TMJ) arthritis, a condition frequently overlooked in patients with JIA, can result in joint damage if not promptly treated. Such damage presents…
  • Abstract Number: 0407 • ACR Convergence 2023

    Meteorological Conditions Contribute to the Joint Ultrasound Findings in Patients with Rheumatoid Arthritis: Kyushu Multicenter Rheumatoid Arthritis Ultrasound Prospective Observational Cohort Study

    Masataka Umeda1, Yushiro Endo2, Tohru Michitsuji3, Ayako Nishino3, Shin-ya Kawashiri3, Shinpei Morimoto4, Masahiko Tuboi5, Naoki Matsuoka5, Keita Fujikawa6, Akinari Mizokami7, Yujiro Arinobu8, Tomomi Tsuru9, Hirokazu Takaoka10, Tamami Yoshitama11, Tomoyuki Asano12, Jun Ishizaki13 and Atsushi Kawakami14, 1Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, 2Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University, Nagasaki, Japan, 3Department of Immunology and Rheumatology, Division of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Medical Sciences, Nagasaki, Japan, 4Innovation Platform & Office for Precision Medicine, Graduate School of Biomedical Sciences, Nagasaki University, Nagasaki, Japan, 5Nagasaki Medical Hospital of Rheumatology, Nagasaki, Japan, 6Japan Community Healthcare Organization, Isahaya General Hospital, Isahaya, Japan, 7Isahaya General Hospital, Isahaya, Japan, 8Department of Clinical Immunology and Rheumatology, Kyushu University Hospital, Fukuoka, Japan, 9Department of Rheumatology, Med.Co. LTA PS Clinic, Fukuoka, Japan, 10Section of Internal Medicine and Rheumatology, Kumamoto Shinto General Hospital, Kumamoto, Japan, 11Yoshitama Clinic for Rheumatic Diseases, Kirishima, Japan, 12Fukushima Medical University, Fukushima, Japan, 13Department of Hematology, Clinical Immunology and Infectious Diseases Ehime University Graduate School of Medicine, Toon, Japan, 14Nagasaki University, Nagasaki, Japan

    Background/Purpose: Various environmental factors are involved in the pathogenesis of rheumatoid arthritis (RA), and meteorological conditions such as temperature and atmospheric pressure have also been…
  • Abstract Number: 0409 • ACR Convergence 2023

    Prevalence of Pulmonary Manifestations in Patients with Newly Diagnosed Rheumatoid Arthritis, Psoriatic Arthritis, and Peripheral Spondyloarthritis

    Lone Winter1, Dirk Skowasch1, Marcel Weber1, Daniel Kütting1, Charlotte Behning2, Peter Brossart3, Simon Petzinna4 and Valentin Sebastian Schäfer3, 1University Hospital Bonn, Bonn, Germany, 2Institute of Medical Biometry, Informatics and Epidemiology, University Hospital of Bonn, Bonn, Germany, 3Clinic of Internal Medicine III, Department of Oncology, Hematology, Rheumatology and Clinical Immunology, University Hospital of Bonn, Bonn, Germany, 4Clinic of Internal Medicine III, Oncology, Hematology, Rheumatology and Clinical Immunology, University Hospital Bonn, Bonn, Germany

    Background/Purpose: Pulmonary impairment is a common, yet poorly understood, extraarticular manifestation in rheumatic diseases, which is often inadequately screened and managed. This can result in…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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