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  • Abstract Number: 248 • 2014 ACR/ARHP Annual Meeting

    Is the Basdai Score Driven By Pain in Ankylosing Spondylitis Patients Treated with Anti-TNF?

    Proton Rahman1, Algis Jovaisas2, William Bensen3, Wojciech Olszynski4, Anna Jaroszynska5, Philip Baer6, Maqbool Sheriff7, Dalton Sholter8, Eliofotisti Psaradellis9, John S. Sampalis9, Francois Nantel10, Allen J Lehman11, Susan Otawa11 and May Shawi10, 1Faculty of Medicine, Memorial University of Newfoundland, St. John's, NF, Canada, 2194 Main Street, University of Ottawa, Ottawa, ON, Canada, 3Division of Rheumatology, McMaster University, Hamilton, ON, Canada, 4University of Saskatchewan, Saskatoon, SK, Canada, 5Private Practice, Burlington, ON, Canada, 6Private Practice, Scarborough, ON, Canada, 7Nanaimo Regional General Hospital, Nanaimo, BC, Canada, 8University of Alberta, Edmonton, AB, Canada, 9JSS Medical Research, Montreal, QC, Canada, 10Janssen Inc., Toronto, ON, Canada, 11Medical Affairs, Janssen Inc., Toronto, ON, Canada

    Background/Purpose The present standard for measuring disease activity in AS is the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) which focuses on five major symptoms…
  • Abstract Number: 247 • 2014 ACR/ARHP Annual Meeting

    Cognitive Task Related Hypoperfusion of Frontal Gyrus in Patients with Chronic Fatigue

    Jason Craggs1, Song Lai2, Ricky Madhavan3, Donald Price4, Michael Robinson1 and Roland Staud5, 1Clinical & Health Psychology, University of Florida, Gainesville, FL, 2Radiation Oncology, University of Florida, Gainesville, FL, 3Medicine/Rheumatology, University of Florida, Gainesville, FL, 4Maxillo-Facial Surgery, University of Florida, Gainesville, FL, 5Dept Med/Rheum/Clin Immun Div, Univ of Florida Med Ctr/JHMHC, Gainesville, FL

    Background/Purpose: Patient with Chronic Fatigue Syndrome (CFS) frequently report cognitive complaints, including lack of concentration and forgetfulness. Previous neuropsychological studies reported attentional and memory dysfunction…
  • Abstract Number: 246 • 2014 ACR/ARHP Annual Meeting

    Neuropathic PAIN in Patients with Ankylosing Spondylitis

    Pinar Borman1, Ferda Kaygisiz2, Aysegul Yaman1 and Aynur Karagoz2, 1Department of Physical Medicine and Rehabilitation, University of Hacettepe Faculty of Medicine, Ankara, Turkey, 2Clinic of Physical Medicine and Rehabilitation, Ankara Training and Research Hospital, Ankara, Turkey

    Background/Purpose: There is only one study in the literature indicating that neuropathic pain occurs in ankylosing spondylitis (AS) (1). Methods: The aim of this cross…
  • Abstract Number: 244 • 2014 ACR/ARHP Annual Meeting

    Onset, Magnitude, and Durability of Pain Relief in Patients with Knee OA Receiving a Fixed-Dose Combination Tablet of Enteric-Coated (EC) Naproxen Plus Immediate-Release (IR) Esomeprazole Magnesium Versus Celecoxib and Placebo: Pooled Results from Two Randomized Controlled Trials

    John Fort1, Robert Holt2, Amy Y. Grahn3, Jana Steinmetz4, Ying Zhang5 and Jeffery Kent6, 1Pozen, Inc, Chapel Hill, NC, 2College of Pharmacy, University of Illinois-Chicago, Vernon Hill, IL, 3Horizon Pharma, Inc., Deerfield, IL, 4Statistics, Premier Research, Naperville, IL, 5Biostatistics, Pozen, Inc, Chapel Hill, NC, 6Medical Affairs, Horizon Pharma, Inc, Deerfield, IL

    Background/Purpose: Over 40% of patients with OA report having significant knee pain every day. (1) Previously published data have demonstrated the overall comparable efficacy of…
  • Abstract Number: 243 • 2014 ACR/ARHP Annual Meeting

    Safety of Solumatrix Diclofenac in Adults with Osteoarthritis: Results of a 12-Month, Phase 3 Study

    Roy Altman1, Allan Gibofsky2, Marc C. Hochberg3, Byron Cryer4, Alan J. Kivitz5, Vibeke Strand6, Olaolu Imasogie7 and Clarence Young8, 1University of California–Los Angeles, David Geffen School of Medicine, Los Angeles, CA, 2Medicine and Public Health, Hospital for Special Surgery, New York, NY, 3Division of Rheumatology & Clinical Immunology, University of Maryland School of Medicine, Baltimore, MD, 4University of Texas Southwestern Medical Center, Dallas, TX, 5Altoona Center for Clinical Research, Duncansville, PA, 6Stanford University, Palo Alto, CA, 7Iroko Pharmaceuticals LLC, Philadelphia, PA, 8150 Rouse Boulevard, Iroko Pharmaceuticals, LLC, Phila, PA

    Background/Purpose:   Osteoarthritis (OA) is a frequent cause of disability in adults. NSAIDs such as diclofenac are often prescribed to treat OA pain. However, NSAIDs…
  • Abstract Number: 242 • 2014 ACR/ARHP Annual Meeting

    WOMAC Pain Score Reflects Preceding Daily Pain Ratings in Knee Osteoarthritis Interventional Randomized Clinical Trials

    Michael H. V. Nguyen1, Renita Evonne Yeasted2 and Thomas J. Schnitzer3, 1University of Washington School of Medicine, Seattle, WA, 2PM&R, Northwestern University, Chicago, IL, 3PM&R and Int Med, Northwestern University, Chicago, IL

    Background/Purpose The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) is a validated and widely used instrument for assessing osteoarthritis (OA) knee and hip pain,…
  • Abstract Number: 241 • 2014 ACR/ARHP Annual Meeting

    Reduced Estimated Glomerular Filtration Rate Was Improved after Cessation of NSAID and Switching to Tramadol Hydrochloride/Acetaminophen Tablets (UltracetTM) in Patients with Chronic Musculoskeletal Pain

    Kenji Miki1,2,3,4, Hiroshi Kajiyama5, Kenrin Shi2,6,7, Shigeshi Mori1, Masao Yukioka8 and Masao Akagi1, 1Department of Orthopaedic Surgery, Faculty of Medicine, Kindai University, Osaka-Sayama, Japan, 2Center for Pain Management, Osaka University Hospital, Suita, Japan, 3Dept. of Rheumatology, Yukioka Hospital, Osaka, Japan, 4Department of Orthopaedic Surgery, Amagasaki Central Hospital, Amagasaki, Japan, 5Department of Rheumatology and Applied Immunology, Saitama Medical University, Saitama, Japan, 6Department of Orthopaedic Surgery, Yukioka Hospital, Osaka, Japan, 7Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, Suita, Japan, 8Department of Rheumatology, Yukioka Hospital, Osaka, Japan

    Background/Purpose: NSAID is widely used in patients with chronic musculoskeletal pain, but often deteriorates renal function with acute decline of estimated glomerular filtration rate (eGFR).…
  • Abstract Number: 240 • 2014 ACR/ARHP Annual Meeting

    An Observational Study on the Influence of Glucocorticoid Exposure on Bone

    Joseph Heath1, Alexander Oldroyd2, Maarten Boers3 and Marwan Bukhari2, 1Faculty of health and medicine, Lancaster University, Lancaster, United Kingdom, 2Lancaster Medical School, Lancaster University, Lancaster, United Kingdom, 3Dep of Epidemiology and Biostatistics, EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, Netherlands

    Background/Purpose It is well known that glucocorticoids are detrimental to bone health and has been postulated that their influence is more than their effect on…
  • Abstract Number: 239 • 2014 ACR/ARHP Annual Meeting

    Does Adjusting BMI for Lean Mass Deficits Affect Calculated Fracture Risk Using FRAX in Rheumatoid Arthritis?

    Brittany Adler1 and Joshua F. Baker2, 1Internal Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, 2Medicine/Rheumatology, University of Pennsylvania and Philadelphia VAMC, Philadelphia, PA

    Background/Purpose Osteoporotic fractures are a cause of morbidity in rheumatoid arthritis (RA) and low body mass index (BMI) is a risk factor for osteoporotic fractures…
  • Abstract Number: 236 • 2014 ACR/ARHP Annual Meeting

    Risk Factors for Prevalent and Progressive Bone Deficits Among Adult Men and Women with Cystic Fibrosis

    Joshua Baker1, Putman Melissa2, Karen Herlyn3, Angela S. Pizzo4, Allen Lapey5, Joel Finklestein2 and Peter A. Merkel6, 1Medicine/Rheumatology, Philadelphia VA Medical Center, Philadelphia, PA, 2Harvard University, Boston, MA, 3Department of Rheumatology, University Hospital Schleswig-Holstein, Lübeck, Germany, 4Mercy Hospital, Portland, ME, 5Cystic Fibrosis Center and Division of Pediatric Pulmonology, Massachusetts General Hospital, Boston, MA, 6University of Pennsylvania, Philadelphia, PA

     Risk Factors for Prevalent and Progressive Bone Deficits Among Adult Men and Women with Cystic FibrosisBackground/Purpose Cystic Fibrosis (CF) is associated with an increased risk…
  • Abstract Number: 235 • 2014 ACR/ARHP Annual Meeting

    Lower P1NP Serum Levels:  a Predictive Marker of Bone Loss after One-Year Follow-up in premenopausal SLE Patients

    Luciana Seguro1, Caio B. Casella1, Valéria Caparbo1, Ricardo M. Oliveira2, Alessandra C Bonfa1, Eloisa Bonfa1 and Rosa M R Pereira1, 1Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 2RDO Diagnosticos Medicos, São Paulo, Brazil

    Background/Purpose: Systemic Lupus Erythematosus (SLE) is associated with high risk of low bone mass/fractures but this risk is still controversial in premenopausal women. Our aim…
  • Abstract Number: 234 • 2014 ACR/ARHP Annual Meeting

    The Decrease in Prescription of Anti-Osteoporotic Drugs Has No Impact on Hip Fracture Incidence

    Karine Briot1, Milka Maravic2 and Christian Roux3, 1Cochin Hospital, Paris Descartes University, Paris, France, 2Hopital Leopold Bellan, Paris, France, 3Paris Descartes University, Cochin Hospital, Paris, France

    Background/Purpose Controversies exist about the change in hip fracture incidence among countries. In France, we previously showed that the incidence of hip fractures decreased in…
  • Abstract Number: 233 • 2014 ACR/ARHP Annual Meeting

    Significance of Serum Marker Levels of Wnt/ß-Catenin Signaling Pathway in Patients with Systemic Autoimmune Diseases Under Glucocorticoid Therapy; A Prospective Study

    Mai Kawazoe, Kotaro Shikano, Kaichi Kaneko, Shotaro Masuoka, Hiroshi Sato, Emiko Shindo, Natsuki Fujio, Sei Muraoka, Makoto Kaburaki, Nahoko Tanaka, Tatsuhiro Yamamoto, Kenji Takagi, Natsuko Kusunoki, Tomoko Hasunuma and Shinichi Kawai, Division of Rheumatology, Department of Internal Medicine, School of Medicine, Faculty of Medicine, Toho University, Tokyo, Japan

    Background/Purpose:  Glucocorticoids are widely used to treat a variety of diseases, including systemic autoimmune diseases. Although glucocorticoids improve the outcome for patients with these diseases,…
  • Abstract Number: 232 • 2014 ACR/ARHP Annual Meeting

    Significance of Serum Srankl and Osteoprotegerin Concentration in Patients with Rheumatoid Arthritis

    Kotaro Shikano, Kaichi Kaneko, Mai Kawazoe, Shotaro Masuoka, Hiroshi Sato, Emiko Shindo, Natsuki Fujio, Makoto Kaburaki, Sei Muraoka, Nahoko Tanaka, Tatsuhiro Yamamoto, Kenji Takagi, Natsuko Kusunoki, Tomoko Hasunuma and Shinichi Kawai, Division of Rheumatology, Department of Internal Medicine, School of Medicine, Faculty of Medicine, Toho University, Tokyo, Japan

    Background/Purpose Rheumatoid arthritis (RA) is known as a cause of secondary osteoporosis. The previous studies reported that receptor activator for nuclear factor κB ligand (RANKL)…
  • Abstract Number: 231 • 2014 ACR/ARHP Annual Meeting

    Factors Predicting Fracture in the over-75s: An Observational Case-Control Study

    Christopher Varley1, James Fowler2, Alexander Oldroyd1 and Marwan Bukhari3, 1Lancaster Medical School, Lancaster University, Lancaster, United Kingdom, 2Faculty of Health and Medicine, Lancaster Univeristy, Lancaster, United Kingdom, 3Rheumatology, Royal Lancaster Infirmary, Lancaster, United Kingdom

    Background/Purpose In the over 75s the diagnosis of osteoporosis may be assumed following a fracture, making the need for a dual energy absorptiometry scan (DEXA)…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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