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  • Abstract Number: 689 • 2013 ACR/ARHP Annual Meeting

    Subclinical Biventricular Systolic Function Is Impaired In Patients With Systemic Sclerosis: A Speckle Tracking-Based Echocardiographic Study

    Sukru Taylan Sahin1, Selen Yurdakul2, Neslihan Yilmaz3, Yonca Cagatay3, Saide Aytekin1 and Sule Yavuz4, 1Cardiology, Istanbul Florence Nightingale Hospital, Cardiology, Istanbul, Turkey, 2Cardiology, Bilim University, Faculty of Medicine, Cardiology Department, Istanbul, Turkey, 3Department of Rheumatology, Bilim University Faculty of Medicine, Istanbul, Turkey, 4Rheumatology, Bilim University, Faculty of Medicine, Rheumatology Department, Istanbul, Turkey

    Subclinical biventricular systolic function is impaired in patients with systemic sclerosis: A speckle tracking-based echocardiographic studyBackground/Purpose : Myocardial involvement is associated with poor prognosis in…
  • Abstract Number: 690 • 2013 ACR/ARHP Annual Meeting

    Assessment Of The New American and European Classification Criteria For Systemic Sclerosis In The Norwegian Systemic Connective Tissue Disease and Vasculitis Registry

    Anna-Maria Hoffmann-Vold1, Torhild Garen2, Oyvind Midtvedt1 and Øyvind Molberg3, 1Rheumatology, Oslo University Hospital, Oslo, Norway, 2Department of Rheumatology, Oslo University Hospital Rikshospitalet, Oslo, Norway, 3Oslo University Hospital, Oslo, Norway

    Background/Purpose: To assess the newly established ACR/EULAR classification criteria for systemic sclerosis 1 (SSc) in a large Norwegian SSc registry cohort. Methods: The Norwegian systemic…
  • Abstract Number: 691 • 2013 ACR/ARHP Annual Meeting

    Descriptive Review Of Morphea Subjects From a Single Cohort Center

    Lesley Portugal1, Muneera Naeem2, Lakshmi N. Moorthy3 and Vivien M. Hsu4, 1Medicine, Robert Wood Johnson Medical School, New Brunswick, NJ, 2Medicine, Mountainside Hospital, Montclair, NJ, 3Pediatric Rheumatology, Robert Wood Johnson Medical School-Rutgers University, New Brunswick, NJ, 4Rheumatology, RWJ Med Schl Scleroderma Prog, New Brunswick, NJ

    Descriptive review of Morphea subjects from a single cohort center Background/Purpose: Morphea, or localized scleroderma, is an idiopathic, rare fibrotic skin disorder that may result…
  • Abstract Number: 692 • 2013 ACR/ARHP Annual Meeting

    Characterization Of Lower Limb Cutaneous Ulcers In Systemic Sclerosis: The Analysis of  424 Lesions

    Jelena Blagojevic1,2, Guya Piemonte1, Laura Benelli1, Francesca Braschi1, Ginevra Fiori1, Felice Galluccio1, Francesca Bartoli1, Lorenza Busco3, Alberto Pignone3, Giulia Carnesecchi1, Gemma Lepri4, Serena Guiducci1 and Marco Matucci Cerinic1, 1Department of Biomedicine, Division of Rheumatology, University of Florence, Florence, Italy, 2Doctorate in Genetics, Oncology and Clinical Medicine, University of Siena, Siena, Italy, 3Department of Internal Medicine, University of Florence, Florence, Italy, 4Department of Internal Medicine, Section of Rheumatology, Transition Clinic, University of Florence, Florence, Italy

    Background/Purpose: Cutaneous ulcers reppresent one of the most frequent complications in course of systemic sclerosis (SSc). They are often disabling and difficult to treat. The…
  • Abstract Number: 693 • 2013 ACR/ARHP Annual Meeting

    Pulmonary Involvement In Mixed Connective Tissue Disease: Slow Progression After 10 Years Of Follow-Up

    Leticia Kawano-Dourado1, Olivia M Dias1, Fernando U Kay2, Thais E H Gripp2, Paula S Gomes3, Ricardo Fuller4, Bruno G Baldi1, Ronaldo A Kairalla1, Carlos R R Carvalho1 and M.Teresa C. Caleiro5, 1Division of Pulmonology - Heart Institute (InCor) - Medical School, University of Sao Paulo, Sao Paulo, Brazil, 2Division of Radiology - Hospital da Clinicas - Medical School, University of Sao Paulo, Sao Paulo, Brazil, 3Division of Pulmonology, Hospital do Servidor do Estado de Sao Paulo, São Paulo, Brazil, 4Division of Rheumatology - Hospital das Clinicas - Medical School, University of Sao Paulo, São Paulo, Brazil, 5Division of Rheumatology - Hospital da Clinicas - Medical School, University of Sao Paulo, Sao Paulo, Brazil

    Background/Purpose: Evaluate the progression of interstitial lung disease (ILD) in a 10-year period of a group of 53 MCTD patients previously evaluated 10 years ago.Methods:…
  • Abstract Number: 694 • 2013 ACR/ARHP Annual Meeting

    Peripheral Bone Marrow-Derived Endothelial Progenitor Cells  and N-Terminal Probrain Natriuretic Peptide  in Scleroderma Mexican Patients With and Without Diastolic Dysfunction: A Preliminary Report

    Jesús Sepúlveda1,2, Olga Vera-Lastra3, Maria Pilar Cruz-Dominguez4, Laura Montiel-Cervantes5, Joaquín Gómez-León6, Luis Robles-Espinoza7, Ramón Lozano-Morales7, Sergio Mendoza-Alvarez1, Rubiraida Molina-Aguilar5, Gabriela Medina8, Jorge Vela-Ojeda9 and Luis J. Jara10, 1Internal Medicine, Instituto Mexicano del Seguro Social, Mexico City, Mexico, 2Unidad de Estudios de Posgrado, Universidad Nacional Autónoma de México, Mexico City, Mexico, 3Internal Medicine, MD, Mexico City, Mexico, 4Division of Research, Hospital de Especialidades Centro Medico Nacional La Raza., Mexico, DF, Mexico, 5Hematology Laboratory, Instituto Mexicano del Seguro Social, Mexico City, Mexico, 6Cardiology Department, Instituto Mexicano del Seguro Social, Mexico City, Mexico, 7Central Laboratory, Instituto Mexicano del Seguro Social, Mexico City, Mexico, 8CMN La Raza IMSS, Seris/Zachila s/n La Raza, Mexico City, Mexico, 9Instituto Mexicano del Seguro Social, Mexico City, Mexico, 10Research and Education, Hospital de Especialidades Centro Medico La Raza, México City, Mexico

    Background/Purpose: Diastolic dysfunction (DD) in systemic sclerosis (SSc) is a marker of increased risk of death. The N-terminal pro-brain natriuretic peptide (NT-proBNP) is a neurohormone…
  • Abstract Number: 695 • 2013 ACR/ARHP Annual Meeting

    Combined Pulmonary Fibrosis and Emphysema (CPFE) In Systemic Sclerosis

    Nicolas Champtiaux1, Vincent Cottin2, Eric Hachulla3, Dominique Valeyre4, Hilario Nunes5, David Launay6, Alice Berezne7, Bruno Crestani8, Loic Guillevin9, Jean-Francois Cordier2 and Luc Mouthon10, 1Service de Médecine Interne, hôpital Cochin, Assistance Publique-Hôpitaux de Paris (AP-HP), Paris, France, 2Division of Pneumology, Hôpital Louis-Pradel, Hospices Civils de Lyon, Lyon 1, Lyon, France, 3Internal Medicine, Lille CEDEX, France, 4Department of Pneumology, Avicenne hospital (APHP), Bobigny, France, 5Department of Pneumology, Avicenne Hospital (AP-HP), Bobigny, France, 6Internal Medicine, Claude Huriez University Hospital, Lille, France, 7Paris Descartes University, Internal Medicine department, Cochin Hospital, Paris, France, 8Pneumology A, Hôpital Bichat, Paris, France, 9Internal Medicine, Cochin University Hospital, Paris, France, 10Department of Internal Medicine, Referral Center for Rare Autoimmune and Systemic Diseases, Hôpital Cochin, AP–HP, Université Paris Descartes, Paris, France, Paris, France

    Combined pulmonary fibrosis and emphysema (CPFE) in systemic sclerosis Background/Purpose: Combined pulmonary fibrosis and emphysema (CPFE) is a recently defined syndrome, in which centrilobular and/or…
  • Abstract Number: 696 • 2013 ACR/ARHP Annual Meeting

    Chronic Periaortitis With Thoracic Aorta Involvement: A New Subtype Of Large Vessel Vasculitis

    Alessandra Palmisano1, Maria Letizia Urban2, Domenico Corradi3, Federico Alberici4, Carlo Salvarani5, Carlo Buzio1 and Augusto Vaglio6, 1Clinical Medicine, Nephrology and Health Sciences, University of Parma, Parma, Italy, 2Nephrology University of Parma, Parma, Italy, 3Pathology University of Parma, Parma, Italy, 4Department of Clinical Medicine, Nephrology and Health Sciences, University of Parma, Parma, Italy, 5Rheumatology, Arcispedale S Maria Nuova-IRCCS, Reggio Emilia, Italy, 6Unit of Nephrology, University Hospital of Parma, Parma, Italy

    Background/Purpose: Chronic periaortitis (CP) is characterised by a fibroinflammatory tissue arising from the adventitia of the abdominal aorta and the iliac arteries and spreading into…
  • Abstract Number: 697 • 2013 ACR/ARHP Annual Meeting

    Longitudinal Assessment Of Pulmonary Function In 304 Norwegian Patients With Systemic Sclerosis

    Anna-Maria Hoffmann-Vold1, Torhild Garen2, Oyvind Midtvedt1, May-Brit Lund3, Jan Tore Gran1 and Øyvind Molberg4, 1Rheumatology, Oslo University Hospital, Oslo, Norway, 2Department of Rheumatology, Oslo University Hospital Rikshospitalet, Oslo, Norway, 3Pulmonary Unit, Oslo University Hospital, Rikshopitalet, Oslo, Norway, 4Oslo University Hospital, Oslo, Norway

    Background/Purpose: The purpose of this study was to asses sequential pulmonary function measurements (forced vital capacity [FVC] % predicted) in a large systemic sclerosis (SSc)…
  • Abstract Number: 698 • 2013 ACR/ARHP Annual Meeting

    Adverse Events With The Use Of Radiotherapy In Patients With Connective Tissue Diseases and Cancer: A Systematic Review and Meta-Analysis

    Maria A. Lopez-Olivo1, Juan A Martínez-López2, Jean H. Tayar3, Mahesh Bavineni4 and Maria E. Suarez-Almazor5, 1General Internal Medicine, University of Texas. M.D Anderson Cancer Center, Houston, TX, 2Rheumatology, Section for Autoimmune Diseases, Jiménez Díaz Foundation University Hospital, Madrid, Spain, 3General Internal Medicine, University of Texs, MD Anderson Cancer Center, Houston, TX, 4Internal Medicine, Louisiana State University Lafayette, Lafayette, LA, 5The Department of General Internal Medicine, The University of Texas, MD Anderson Cancer Center, Houston, TX

    Background/Purpose: In the era of modern medicine, radiotherapy remains a cornerstone for the multi-modality cancer treatment. Methods: We conducted a comprehensive search for any study…
  • Abstract Number: 699 • 2013 ACR/ARHP Annual Meeting

    Severity Of Muscle Weakness Predicts Disability In Scleroderma

    Julie J. Paik1, Fredrick M. Wigley1, Amanda Mejia2 and Laura K. Hummers1, 1Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 2Biostatistics, Johns Hopkins Bloomberg School of Publich Health, Baltimore, MD

    Title: Severity of muscle weakness predicts disability in scleroderma Background/Purpose: The Health assessment questionnaire disability index (HAQ-DI) is a self-administered questionnaire that is a patient…
  • Abstract Number: 700 • 2013 ACR/ARHP Annual Meeting

    Osteoporosis and Fracture Risk In Outpatients With Systemic Sclerosis

    Veronica Codullo1, Flora Inverardi2, Silvia Breda3, Laura Bogliolo4, Francesca De Nard5, Giovanni Cagnotto6, Roberto Caporali7 and Carlomaurizio Montecucco8, 1Rheumatology, IRCCS Policlinico San Matteo Foundation, Pavia, Italy, 2Rheumatology, Division of Rheumatology, IRCCS Policlinico San Matteo Foundation and University of Pavia, Pavia, Italy, 3Division of Rheumatology, University of Pavia, IRCCS Foundation Policlinico S. Matteo, Pavia, Italy, 4IRCCS Foundation Policlinico San Matteo, Pavia, Italy, 5University of Pavia, IRCCS Policlinico San Matteo Foundation, Pavia, Italy, 6IRCCS Policlinico San Matteo, Pavia, Italy, 7Rheumatology, Rheumatology, IRCCS Policlinico San Matteo Foundation and University of Pavia, Pavia, Italy, 8Rheumatology, University and IRCCS Policlinico S. Matteo Foundation, Pavia, Italy

    Background/Purpose: Osteoporosis (OP) is a frequent complication of a number of chronic inflammatory diseases. Only Rheumatoid Arthritis (RA) is included in the FRAX algorythm to…
  • Abstract Number: 701 • 2013 ACR/ARHP Annual Meeting

    Extension Of Cardiac Damage Through The Delayed Enhancement Of Cardiac Magnetic Resonance: Predictive Value Of a Combined Approach Based On Clinical and Laboratory Findings, EKG-Holter and Cardiac Magnetic Resonance

    Silvia Laura Bosello1, Giacomo De Luca1, Agostino Meduri2, Giorgia Berardi1, Manuela Rucco1, Giovanni Canestrari1, Federico Parisi1 and Gianfranco Ferraccioli1, 1Division of Rheumatology, Institute of Rheumatology and Affine Sciences, Catholic University of the Sacred Heart, Rome, Italy, 2INSTITUTE OF RADIOLOGY - Catholic University of the Sacred Heart, ROME, Italy

    Background/Purpose: Cardiac involvement is a relevant prognostic determinant in Systemic Sclerosis (SSc), but the diagnosis is often delayed due to the lack of a specific…
  • Abstract Number: 702 • 2013 ACR/ARHP Annual Meeting

    Prediction Of Worsening Of Skin Fibrosis In Patients With Diffuse Systemic Sclerosis Using The EULAR Scleroderma Trials and Research (EUSTAR) Registry

    Britta Maurer1, Nicole Graf2, Beat A. Michel3, Carola Metzig4, Vivian Lanius4, Dinesh Khanna5 and Oliver Distler1, 1Division of Rheumatology, University Hospital Zurich, Zurich, Switzerland, 2graf biostatistics, Winterthur, Switzerland, 3Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland, 4Bayer Pharma AG, Berlin, Germany, 5University of Michigan Health System, Ann Arbor, MI

    Background/Purpose: To identify predictive parameters for the progression of skin fibrosis in patients with diffuse cutaneous SSc (dcSSc) to enable 1) risk-stratification in clinical practice…
  • Abstract Number: 703 • 2013 ACR/ARHP Annual Meeting

    Correlation Between Patient Self-Report Of Symptoms Of Raynaud’s Phenomenon and Objective Assessment Of Digital Microvascular Perfusion Using Infrared Thermography

    Marina Scolnik1,2, Bhavisha Vasta2, Darren Hart2, Jacqueline A. Shipley2, Sue Brown2, Eleanor Korendowych2, Neil J McHugh2,3 and John D. Pauling2,3, 1Rheumatology Section, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina, 2Rheumatology, Royal National Hospital for Rheumatic Diseases, Bath, United Kingdom, 3Department of Pharmacy and Pharmacology, University of Bath, Bath, United Kingdom

    Background/Purpose: Patient self-report of digital colour changes form the basis of a clinical diagnosis of Raynaud's phenomenon (RP) and help classify patients with early systemic…
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