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  • Abstract Number: 901 • 2014 ACR/ARHP Annual Meeting

    Rate of Serum Uric Acid (SUA) Assessment in Gout Patients Treated with Urate-Lowering Therapy: Treating to Target?

    Robert Morlock1, David M. Kern2, Ozgur Tunceli2, Siting Zhou2, Laura Horne3, Sulabha Ramachandran3 and Hyon K. Choi4, 14939 Directors Place, Ardea Biosciences, San Diego, CA, 2HealthCore, Inc., Wilmington, DE, 3AstraZeneca, Wilmington, DE, 4Division of Rheumatology, Allergy, and Immunology Massachusetts General Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: Gout is the most common form of inflammatory arthritis and is caused by chronic hyperuricemia, leading to urate crystal deposition disease and subsequent intermittent…
  • Abstract Number: 900 • 2014 ACR/ARHP Annual Meeting

    Race and Sex Specific Incidence Rates and Predictors of Total Knee Arthroplasty: Data from the Osteoarthritis Initiative, 7 Years Follow up

    Jamie E. Collins1, Bhushan Deshpande1, Jeffrey N. Katz2 and Elena Losina1, 1Orthopaedic and Arthritis Center for Outcomes Research, Brigham and Women's Hospital, Boston, MA, 2Rheumatology and Orthopedics, Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Total knee arthroplasty (TKA) is used to reduce pain and improve functional status in persons with symptomatic knee osteoarthritis (OA). Several studies point to…
  • Abstract Number: 919 • 2014 ACR/ARHP Annual Meeting

    Glucocorticoid Exposure and Fracture Risk in a Large Cohort of Commercially-Insured Rheumatoid Arthritis Patients Under Age 65

    Akhila Balasubramanian1, Sally Wade2, Robert A Adler3, Celia Fang (Lin)4, Michael Maricic5, Cynthia O'Malley1, Kenneth G. Saag6 and Jeffrey R. Curtis7, 1Center for Observational Research, Amgen, Inc., Thousand Oaks, CA, 2Wade Outcomes Research and Consulting, Salt Lake City, UT, 3Internal Medicine, Hunter Holmes McGuire VA Medical Center, Richmond, VA, 4Amgen, Thousand Oaks, CA, 5Catalina Pointe Rheumatology, Tucson, AZ, 6Immunology & Rheumatology, The University of Alabama at Birmingham, Birmingham, AL, 7The University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose Systemic glucocorticoid use can increase fracture risk, although dose-specific effects are not well understood, especially in younger adults.  Underlying diseases (e.g., rheumatoid arthritis [RA])…
  • Abstract Number: 918 • 2014 ACR/ARHP Annual Meeting

    Findings from Denosumab (Prolia®) Postmarketing Safety Surveillance for Serious Infections

    W Golden1, DB Crittenden1, M Uhart1, RB Wagman1, C Stehman-Breen1, S Papapoulos2 and NB Watts3, 1Amgen Inc., Thousand Oaks, CA, 2Leiden University Medical Center, Leiden, Netherlands, 3Mercy Health Osteoporosis and Bone Health Services, Cincinnati, OH

    Background/Purpose: Prolia has marketing authorization in the EU, US, Canada, Japan, and over 40 countries or administrative districts worldwide for the treatment of postmenopausal women…
  • Abstract Number: 917 • 2014 ACR/ARHP Annual Meeting

    Evaluation of Invasive Oral Procedures and Events in Women with Postmenopausal Osteoporosis Treated with Denosumab: Results from the Pivotal Phase 3 Fracture Study Extension

    Nelson B. Watts1, John T. Grbic2, Michael McClung3, Socrates Papapoulos4, David Kendler5, Christence S. Teglbjaerg6, Lawrence O'Connor7, Rachel B. Wagman7, Eric Ng7, Nadia S. Daizadeh7 and Pei-Ran Ho7, 1Mercy Health Osteoporosis and Bone Health Services, Cincinnati, OH, 2Columbia University, New York, NY, 3Oregon Osteoporosis Center, Portland, OR, 4Leiden University Medical Center, Leiden, Netherlands, 5University of British Columbia, Vancouver, BC, Canada, 6Center for Clinical and Basic Research, Ballerup, Denmark, 7Amgen Inc., Thousand Oaks, CA

    Background/Purpose: Osteonecrosis of the jaw (ONJ) is a rare but serious adverse event of some antiresorptive therapies, including denosumab (DMAb), and invasive oral procedures and…
  • Abstract Number: 916 • 2014 ACR/ARHP Annual Meeting

    Effects of 2 Years of Treatment with Romosozumab Followed By 1 Year of Denosumab or Placebo in Postmenopausal Women with Low Bone Mineral Density

    MR McClung1, A Chines2, JP Brown3, A Diez-Perez4, H Resch5, J Caminis6, MA Bolognese7, S Goemaere8, HG Bone9, JR Zanchetta10, J Maddox2, O Rosen2, S Bray11 and A Grauer2, 1Oregon Osteoporosis Center, Portland, OR, 2Amgen Inc., Thousand Oaks, CA, 3Laval University and CHU de Québec Research Centre, Quebec City, QC, Canada, 4Autonomous University of Spain, Barcelona, Spain, 5St. Vincent Hospital, Vienna, Austria, 6UCB, Raleigh, NC, 7Bethesda Health Research Center, Bethesda, MD, 8Ghent University Hospital, Ghent, Belgium, 9Michigan Bone and Mineral Clinic, Detroit, MI, 10Instituto de Investigaciones Metabólicas, Buenos Aires, Argentina, 11Amgen Ltd., Cambridge, United Kingdom

    Background/Purpose: We previously reported that 1 year of treatment with the sclerostin antibody romosozumab (Romo) was associated with increased bone mineral density (BMD) and bone…
  • Abstract Number: 914 • 2014 ACR/ARHP Annual Meeting

    A Predictive Model of Disease Outcome in Rituximab-Treated Myositis Patients Using Clinical Features, Autoantibodies, and Serum Biomarkers

    Jeannette Olazagasti1, Cynthia S. Crowson2, Molly S. Hein1, Consuelo Lopez de Padilla1, Rohit Aggarwal3, Chester V. Oddis4 and Ann M. Reed1, 1Rheumatology, Mayo Clinic, Rochester, MN, 2Health Sciences Research, Mayo Clinic, Rochester, MN, 3Medicine, University of Pittsburgh, Pittsburgh, PA, 4Rheum/Clinical Immunology, University of Pittsburgh, Pittsburgh, PA

    Background/Purpose: Develop predictive models of early (8 week) and late (24 week) disease outcomes using clinical features, autoantibodies, and serum biomarkers in patients with refractory…
  • Abstract Number: 913 • 2014 ACR/ARHP Annual Meeting

    Long Term Outcomes of Patients with Moderate Creatine Kinase (CK) Elevation Seen in a Rheumatology Clinic

    Lyudmila Kirillova1, Abraham Tacang2, Andrea Berger3, Thomas M. Harrington4 and Androniki Bili1, 1Rheumatology, Geisinger Health System, Danville, PA, 2Internal medicine - Pediatric, Geisinger Health System, Danville, PA, 3Center for Health Research, Geisinger Health System, Danville, PA, 4Dept of Rheumatology, Geisinger Health System, Danville, PA

    Background/Purpose: Asymptomatic or mildly symptomatic patients with moderate creatine kinase (CK) elevation are commonly referred to rheumatologists. In patients without a clearly established diagnosis, the…
  • Abstract Number: 915 • 2014 ACR/ARHP Annual Meeting

    Increased Risk of Myocardial Infarction in Dermatomyositis and Polymyositis: A General Population-Based Cohort Study

    Kateryna Vostretsova1, Erin Carruthers2, Eric C. Sayre2, John Esdaile2 and J Antonio Avina-Zubieta3, 1University of British Columbia, Vancouver, BC, Canada, 2Arthritis Research Centre of Canada, Richmond, BC, Canada, 3Experimental Medicine, University of British Columbia, Department of Experimental Medicine, Vancouver, BC, Canada

    Background/Purpose Patients with polymyositis (PM) and dermatomyositis (DM) may have an increased risk of myocardial infarction (MI), similar to other connective tissue diseases. However, no…
  • Abstract Number: 897 • 2014 ACR/ARHP Annual Meeting

    Resting State Functional Connectivity Differs Between Chronic Fatigue Syndrome Patients and Healthy Controls

    Jason Craggs1, Charles Gay1, Andrew O'Shea1, Ricky Madhavan2, Donald Price3, Michael Robinson1 and Roland Staud4, 1Clinical & Health Psychology, University of Florida, Gainesville, FL, 2Medicine/Rheumatology, University of Florida, Gainesville, FL, 3Maxillo-Facial Surgery, University of Florida, Gainesville, FL, 4Dept Med/Rheum/Clin Immun Div, Univ of Florida Med Ctr/JHMHC, Gainesville, FL

    Background/Purpose: Examining neural activity in the absence of task (i.e. resting state) is an active area of research. Functional connectivity, defined as correlations in BOLD…
  • Abstract Number: 893 • 2014 ACR/ARHP Annual Meeting

    Polysymptomatic Distress Categories for Clinical and Research Use

    Frederick Wolfe1, Brian T. Walitt2, Johannes Rasker3, Robert S. Katz4 and Winfried Häuser5, 1National Data Bank for Rheumatic Diseases, Wichita, KS, 2Rheumatology, Washington Hospital Center, Washington, DC, 3Dpt. Psychology, Health and Technology, University Twente, Enschede, Netherlands, 4Rush Medical College, Chicago, IL, 5Klinikum Saarbrücken, Saarbrücken, Germany

    Background/Purpose: The polysymptomatic distress (PSD) scale is derived from variables used in the 2010 American College of Rheumatology (ACR) fibromyalgia (FM) criteria as modified for…
  • Abstract Number: 894 • 2014 ACR/ARHP Annual Meeting

    Small Fiber Neuropathy in Women with Fibromyalgia. a Clinical-Pathological Correlation Using Confocal Corneal Biomicroscopy

    Manuel Ramírez-Fernández1, Laura-Aline Martinez-Martinez2, Angelica Vargas-Guerrero3, Manuel Martínez-Lavín4, Everardo Hernandez Quintela1 and Jorge Velazco-Caspia1, 1Asociación para Evitar la Ceguera en México, Mexico City, Mexico, 2Instituto Nacional de Cardiologia, Mexico City, Mexico, 3Rheumatology, Instituto Nacional de Cardiologia, Mexico City, Mexico, 4Chief Rheumatology, Instituto Nacional de Cardiologia, Mexico City, Mexico

    Background/Purpose: A consistent line of investigation proposes that fibromyalgia is a sympathetically maintained neuropathic pain syndrome (Semin Arthritis Rheum 2000;29:197). This view has been recently reinforced…
  • Abstract Number: 895 • 2014 ACR/ARHP Annual Meeting

    The Fibromyalgia Syndrome and Widespread Pain Frequency in Active Duty U.S. Service Members with Posttraumatic Stress Disorder

    Bernard Hildebrand1, Jay B. Higgs1, Douglas Williamson2, Edna Foa3, Patricia Resick4, Jim Mintz2, Antoinette Brundige2, Kevin Kelly5, Adam Borah5, Stacey Young-McCaughan2, Brett Litz6, Elizabeth Hembree3 and Alan Peterson2, 1Rheumatology, San Antonio Military Medical Center, JBSA - Fort Sam Houston, TX, 2The University of Texas Health Science Center at San Antonio, San Antonio, TX, 3University of Pennsylvania, Philadelphia, PA, 4Duke University, Durham, NC, 5Carl R. Darnall Army Medical Center, Fort Hood, TX, 6VA Boston Healthcare System, Boston, MA

    Background/Purpose:  Posttraumatic stress disorder (PTSD) and pain are common amongst US military service members who have deployed to Iraq and Afghanistan.  Studies suggest the co-morbidity…
  • Abstract Number: 896 • 2014 ACR/ARHP Annual Meeting

    Development of Fibromyalgia and Polysymptomatic Distress Definitions in the National Health Interview Survey

    Brian Walitt1, Richard Nahin2, Robert S. Katz3, Martin J. Bergman4 and Frederick Wolfe5, 1MedStar Health, Washington, DC, 2National Center for Complementary and Alternative Medicine, National Institutes of Health, Bethedsa, MD, 3Rush Medical College, Chicago, IL, 4Taylor Hospital, Ridley Park, PA, 5National Data Bank for Rheumatic Diseases, Wichita, KS

    Background/Purpose: A detailed understanding of fibromyalgia and its symptoms in the US population would be valuable. The National Health Interview Survey (NHIS) is the principal…
  • Abstract Number: 892 • 2014 ACR/ARHP Annual Meeting

    Symptom Increase in Fibromyalgia Is Not Consistent with the Central Sensitization or Central Hyperresponsiveness Hypothesis

    Frederick Wolfe1, Brian T. Walitt2, Johannes Rasker3, Robert S. Katz4 and Winfried Häuser5, 1National Data Bank for Rheumatic Diseases, Wichita, KS, 2Rheumatology, Washington Hospital Center, Washington, DC, 3Dpt. Psychology, Health and Technology, University Twente, Enschede, Netherlands, 4Rush Medical College, Chicago, IL, 5Klinikum Saarbrücken, Saarbrücken, Germany

    Background/Purpose: The current dominant hypothesis explains fibromyalgia (FM) as a centralized pain state in which the CNS originates or amplifies pain, which is then accompanied…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

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