Abstract Number: 1928 • 2013 ACR/ARHP Annual Meeting
Outcomes Of The Fast-Track Pathway In Giant Cell Arteritis: A Sight Saver
Outcomes of the fast-track pathway in Giant cell arteritis: A sight saverBackground/Purpose: Giant cell arteritis (GCA) is a medical emergency, with permanent visual loss…Abstract Number: 1888 • 2013 ACR/ARHP Annual Meeting
Transcriptional Regulation Of Peptidylarginine Deiminase Type IV: Implications For Rheumatoid Arthritis
Background/Purpose: High titers of anti-citrullinated protein/peptide antibodies (ACPA) have been detected in sera of rheumatoid arthritis (RA) patients, implicating citrullinating enzymes in the pathogenesis of…Abstract Number: 1889 • 2013 ACR/ARHP Annual Meeting
Genome-Wide Association Study Of Knee Radiographic Osteoarthritis In African-American Populations
Background/Purpose: Few SNPs and susceptibility genes have been identified in previous genome-wide and candidate gene association studies for knee radiographic osteoarthritis (OA). Nearly all studies…Abstract Number: 1890 • 2013 ACR/ARHP Annual Meeting
Chemokine Receptor Polymorphisms On Chromosome 3 Are Associated With Anticitrullinated Protein Antibody Specificities In African Americans With Rheumatoid Arthritis
Background/Purpose: ACPA antibody specificities to citrullinated autoantigens (e.g., histones, vimentin, fibrinogen) are associated with the preclinical phase of RA and may predict the onset of…Abstract Number: 1891 • 2013 ACR/ARHP Annual Meeting
Proteomic Profile Of Tears: Can It Help To Diagnose Juvenile Arthritis – Associated Uveitis Prior To The Clinical Signs Of Joints Inflammation
Background/Purpose: Approximately 6% of all cases of uveitis arise in children (Nguyen, Foster, 1998). One of the common causes of uveitis is Juvenile Idiopathic Arthritis…Abstract Number: 1892 • 2013 ACR/ARHP Annual Meeting
High-Throughput Immunoglobulin G Fab Glycosylation Profiling Reveals Differential Glycosylation On Fab and Fc
Background/Purpose: Rheumatoid arthritis is known to improve during pregnancy, and a flare of disease activity is observed after delivery (1). N-glycosylation of the constant region…Abstract Number: 1893 • 2013 ACR/ARHP Annual Meeting
Altered DNA Methylation Profiles In Individuals With Osteoarthritis
Background/Purpose: Major risk factors associated with osteoarthritis (OA) development include age, joint stress/injury, obesity, and genetic predisposition. In recent years, the role epigenetic processes that…Abstract Number: 1894 • 2013 ACR/ARHP Annual Meeting
Association Of Alleles and Amino Acids Of The Major Histocompatibility Complex Class I Chain-Related Gene A With Psoriatic Disease
Background/Purpose: We previously reported associations between alleles of the major histocompatibility complex class I chain-related gene A (MICA) and psoriatic disease that were independent of…Abstract Number: 1895 • 2013 ACR/ARHP Annual Meeting
Identification Of Aberrant Pathways In Osteoarthritis Using RNA-Seq
Background/Purpose: Osteoarthritis (OA) is a prevalent joint disease that is characterized by the destruction of articular cartilage, although the disease process affects all joint tissues. …Abstract Number: 1896 • 2013 ACR/ARHP Annual Meeting
Arthritis Associated Sequence Alterations Within a Genetic Susceptibility Region Of Mouse Chromosome 3; A Genomic Region Which Is Syntenic With a Prominent Non-MHC Locus In Rheumatoid Arthritis
Background/Purpose: Rheumatoid arthritis (RA) is an autoimmune disease that results in inflammatory destruction of synovial joints in affected patients. The involvement of genetic and epigenetic…Abstract Number: 1897 • 2013 ACR/ARHP Annual Meeting
Algorithms Using Genome-Wide SNP Analysis For Prediction Of Progression Of Joint Space Narrowing Or Erosion In Rheumatoid Arthritis Patients Using Data From Multiple Medical Cohorts
Background/Purpose: Although not yet fully possible, ideally, since patients with rapidly progressing joint space narrowing/erosion exist, predicting progression of joint space narrowing/erosion would be pivotal…Abstract Number: 1898 • 2013 ACR/ARHP Annual Meeting
Repression Of Wolf-Hischhorn Syndrome Candidate-1 (WHSC1) Contributes To The Osteoarthritis-Inducing Cartilage Loss Of Functions
Background/Purpose: Accumulation of senescent p16INK4A-positive cells within numerous tissues through out life span contributes to the onset of several age-related disease such as intervertebral disc…Abstract Number: 1899 • 2013 ACR/ARHP Annual Meeting
Interferon Regulatory Factor 5 Gene Variant rs2004640 Is Associated With Carotid Intimal Medial Thickness In Rheumatoid Arthritis Patients
Background/Purpose : Rheumatoid arthritis (RA) is a chronic inflammatory joint disease which is associated with an increased cardiovascular (CV) risk.. An important process in atherogenesis…Abstract Number: 1900 • 2013 ACR/ARHP Annual Meeting
Mass Spectrometry-Based Salivary Proteomics For The Discovery Of Novel Diagnostic Biomarkers For Primary Sjögren’s Syndrome and Its Clinical Subsets
Background/Purpose: Nowadays, the advances of novel proteomic technologies are encouraging research projects for generating reliable diagnostic biomarkers for primary Sjögren’s syndrome (pSS) to be used…Abstract Number: 1901 • 2013 ACR/ARHP Annual Meeting
Genetic Variants In OPG and ANKH Are Associated With Severity Ofankylosis In Ankylosing Spondylitis In a Korean Cohort
Background/Purpose: Spinal ankylosis,which represents the most severe radiologic change in ankylosing spondylitis (AS),is associated with permanent work disability as well as decreased quality of life.…