Abstracts Archive - Page 2093 of 2607 - ACR Meeting Abstracts

Abstract Number: 2121 • 2014 ACR/ARHP Annual Meeting
Real-World Cost Comparison of Urate Lowering Therapies in Patients with Gout and Moderate to Severe Chronic Kidney Disease
Ghaith Mitri¹, Eric Wittbrodt¹, Robin Turpin¹, Beni Tidwell² and Kathy Schulman², ¹Medical Affairs, Takeda Pharmaceuticals International, Deerfield, IL, ²Outcomes Research Solutions, Inc., Waltham, MA
Background/Purpose Gout flare prevention relies heavily on urate-lowering therapies (ULT) such as allopurinol (ALP) and febuxostat (FBX) but clinical decision-making in patients with moderate to…
Abstract Number: 2122 • 2014 ACR/ARHP Annual Meeting
Variation in the Prescribing Practices of Biologic Dmards
Heather O. Tory¹, Josephine A. Awosogba², Amish J. Dave², Jonathan S. Coblyn², Daniel H. Solomon² and Sonali P. Desai², ¹Rheumatology Program, Division of Immunology, Boston Children's Hospital, Boston, MA, ²Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA
Background/Purpose: Biologic DMARDs (bDMARDs) are effective yet expensive treatments for RA. Variability in the prescribing practices of rheumatologists using these agents may be attributable to…
Abstract Number: 2123 • 2014 ACR/ARHP Annual Meeting
Significant State-Level Variation in Source of Biologic Drug Coverage Among Beneficiaries with Rheumatoid Arthritis
Chris Tonner¹, Gabriela Schmajuk² and Jinoos Yazdany², ¹3333 California Street, Box 09, University of California, San Francisco, San Francisco, CA, ²Medicine, University of California, San Francisco, San Francisco, CA
Background/Purpose: Biologic drugs can be obtained both through Medicare's Part B medical benefit (physician administered drugs) or Part D pharmacy benefit (self-administered drugs). Coverage for…
Abstract Number: 2124 • 2014 ACR/ARHP Annual Meeting
Characteristics of Medicare Beneficiaries Travelling Long Distances to Visit a Rheumatologist
Gabriela Schmajuk¹, Chris Tonner² and Jinoos Yazdany³, ¹Medicine / Rheumatology, UCSF / San Francisco VA, San Francisco, CA, ²3333 California Street, Box 09, University of California, San Francisco, San Francisco, CA, ³Medicine, University of California, San Francisco, San Francisco, CA
Background/Purpose: Studies of the distribution of rheumatologists across the United States suggest that a significant number of patients travel long distances to visit a rheumatologist. …
Abstract Number: 2125 • 2014 ACR/ARHP Annual Meeting
Burden of Illness in Refractory Gouty Arthritis: A One-Year Prospective Multinational, Observational Study
Louis Bessette¹, Frédéric Lioté², Carmen Moragues³, Rüdiger Moericke⁴, Zhang Zhiyi⁵, Alberto Ferreira⁶, Pascal Lecomte⁶, Sophia Kessabi⁶, Haijun Tian⁷ and Jasvinder A. Singh^8,9, ¹CHUL, Quebec, QC, Canada, ²Hôpital Lariboisière & University Paris Diderot, Paris, France, ³Hospital Platón, Barcelona, Italy, ⁴Institut für Präventive Medizin & Klinische Forschung GbR, Magdeburg, Germany, ⁵The First Affiliated Hospital of Haerbin Medical University, Haerbin, China, ⁶Novartis Pharma AG, Basel, Switzerland, ⁷Novartis Pharmaceuticals Corporation, East Hanover, NJ, ⁸Mayo Clinic, Rochester, MN, ⁹University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Refractory gouty arthritis (RGA) is a condition characterized by appearance of recurrent flares and contraindication, intolerance, or lack of efficacy to first-line anti-inflammatory therapy…
Abstract Number: 2126 • 2014 ACR/ARHP Annual Meeting
The Utility of Digital Activity Fluorescence Optical Imaging in Quantifying Hand and Wrist Inflammation in Rheumatic Diseases
Yogan Kisten¹, Noémi Györi¹, Hamed Rezaei^2,3, Adrian Levitsky⁴, Anna Karlsson¹, Erik af Klint³ and Ronald van Vollenhoven^3,5, ¹Department of Medicine, Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), The Karolinska Institute,Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), Stockholm, Sweden, ²Department of Medicine, Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), The Karolinska Institute, Stockholm, Sweden, ³Department of Medicine, Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), The rheumatology clinic of the Karolinska University Hospital, Stockholm, Sweden, ⁴The Karolinska Institute,Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), Stockholm, Sweden, ⁵Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), The Karolinska Institute, Stockholm, Sweden
Background/Purpose The objective detection and quantification of disease activity in its earliest pathophysiological stage is critical for achieving optimal therapy results. Fluorescence optical imaging (FOI)…
Abstract Number: 2127 • 2014 ACR/ARHP Annual Meeting
Subclinical Arthritis Is Detected By Macrophage Targeting and Positron Emission Tomography (PET) in Early RA Patients in Clinical Remission
Y.Y.J. Gent¹, M.M. ter Wee¹, D den Uyl¹, N. Ahmadi², W.F. Lems³, O.S. Hoekstra⁴, A.E. Voskuyl¹ and C.J. Van der Laken³, ¹Rheumatology, VU University Medical Center, Amsterdam, Netherlands, ²Radiology, VU University Medical Center, Amsterdam, Netherlands, ³Rheumatology, VU Medical Center, Amsterdam, Netherlands, ⁴Nuclear Medicine, VU Medical Center, Amsterdam, Netherlands
Background/Purpose: Recurrent flares in RA patients in complete remission (CR) are not an uncommon phenomenon. Studies with advanced imaging techniques have suggested that residual subclinical…
Abstract Number: 2128 • 2014 ACR/ARHP Annual Meeting
Effectiveness of ¹⁸f-Fluoro-Dexoxyglucose Positron Emission Tomography for the Diagnosis of Polymyalgia-like Illness
Hideyuki Horikoshi¹, Takashi Nakanishi¹, Reiko Takahashi¹, Fumihiko Kimura² and Kenji Itoh¹, ¹Division of Rheumatology, Department of Internal Medicine, National Defense Medical College, Tokorozawa, Japan, ²National Defense Medical College, Tokorozawa, Japan
Background/Purpose: Polymyalgia rheumatica (PMR) is an inflammatory condition that affects the elderly. It is characterized by pain and stiffness in the shoulder and pelvic girdles. …
Abstract Number: 2129 • 2014 ACR/ARHP Annual Meeting
Sensitivity and Specificity of the “Green Nail” Sign in Fluorescence Optical Imaging in Psoriatic Arthritis
Oliver Wiemann¹, Stephanie G. Werner¹, Hannah Röver¹, Gudrun Lind-Albrecht¹, Sabine Mettler¹, Marina Backhaus² and Hans-Eckhard Langer¹, ¹RHIO (Rheumatology, Immunology, Osteology), Duesseldorf, Germany, ²Rheumatology/Immunology, Charite University Hospital, Berlin, Germany
Background/Purpose ICG-enhanced fluorescence optical imaging (FOI) is a novel technology for the assessment of inflammation in arthritis [1,2]. Recent work suggested that a “green nail”…
Abstract Number: 2105 • 2014 ACR/ARHP Annual Meeting
Nonsurgical Treatment Patterns in Patients with Chronic Spinal Cord Injury
Brian Le¹, Monique Bethel², Lauren Bailey³, Frances Weaver³, Stephen Burns⁴, Jelena Svircev⁴, Michael Heggeness⁵ and Laura Carbone⁶, ¹Medicine, Georgia Regents University, Augusta, GA, ²Internal Medicine, Georgia Regents University, Augusta, GA, ³Edward Hines Jr. VA Hospital, Chicago, IL, ⁴VA Puget Sound Healthcare System, Seattle, WA, ⁵Orthopaedic Surgery, University of Kansas School of Medicine, Kansas City, KS, ⁶Medicine, Charlie Norwood VA Medical Center, Augusta, GA
Background/Purpose: Sublesional loss of bone mineral density is a common complication in patients with chronic spinal cord injury (SCI) putting them at high risk for…
Abstract Number: 2104 • 2014 ACR/ARHP Annual Meeting
Effectiveness of a Workplace Integrated Care Intervention on Work Productivity in Workers with Rheumatoid Arthritis
Myrthe van Vilsteren^1,2, Cécile Boot^1,2, Dirkjan van Schaardenburg³, Romy Steenbeek^2,4, A.E. Voskuyl⁵ and Johannes Anema^1,2,6, ¹Department of Public and Occupational Health, EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, Netherlands, ²Body@Work, Research Center Physical Activity, Work and Health, TNO-VU University Medical Center, Amsterdam, Netherlands, ³Dr Jan van Breemenstraat 2, Reade, Amsterdam, Netherlands, ⁴TNO Work and Health, Hoofddorp, Netherlands, ⁵Rheumatology, VU University Medical Center, Amsterdam, Netherlands, ⁶Research Center for Insurance Medicine AMC-UMCG-UWV-VU University Medical Center, Amsterdam, Netherlands
Background/Purpose: Rheumatoid arthritis (RA) is a chronic inflammatory disease with a profound impact on a person’s working life. Besides permanent work disability and sick leave,…
Abstract Number: 2103 • 2014 ACR/ARHP Annual Meeting
Benefits of Early Onset of DAS28 (CRP) <2.6 on Physical Functioning, Quality of Life and Resource Use Among RA Patients in a Clinical Practice Setting
E Alemao¹, S Joo², H Kawabata¹, S Banerjee¹, M Frits³, C Iannaccone³, N Shadick³ and M Weinblatt³, ¹Bristol-Myers Squibb, Princeton, NJ, ²Bristol-Myers Squibb, Hopewell, NJ, ³Brigham and Women's Hospital, Boston, MA
Background/Purpose: Guidelines in RA recommend that treatment should be aimed at reaching a target of remission or low disease activity (LDA) as soon as possible,…
Abstract Number: 2102 • 2014 ACR/ARHP Annual Meeting
A Tissue-Specific Lincrna in the TRAF1-C5 Risk Locus As a Putative Cis-Regulator, Bridging Genetics and Disease
Tobias Messemaker¹, Rute Marques¹, Tom Huizinga¹, Alwin Adriaans¹, Aleida Bakker¹, Arend Berendsen¹, Nina Daha², R E M Toes¹, Harald Mikkers³ and Fina Kurreeman¹, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Leiden University Medical Center, Leiden, Netherlands, ³Molecular Cell Biology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose In the last decade genome wide association studies (GWAS) have identified genetic polymorphisms that associate with Rheumatoid arthritis (RA). However, the way these genetic…
Abstract Number: 2101 • 2014 ACR/ARHP Annual Meeting
Epigenetic Study of Advanced Ankylosis in Patients with Ankylosing Spondylitis
Darren O'Reilly¹, Yuhua Zhang², Nayef Al Ghanim³, Rose Ardern³, Alexandra Munn³, Sean Hamilton³, Guangju Zhai² and Proton Rahman³, ¹Memorial University of Newfoundland, St. John's, NF, Canada, ²Discipline of Genetics, Faculty of Medicine, Memorial University of Newfoundland, St. John's, NF, Canada, ³Faculty of Medicine, Memorial University of Newfoundland, St. John's, NF, Canada
Background/Purpose: Ankylosing spondylitis (AS) is an inflammatory spinal disease characterized by ankylosis of the spine. A subset of patients develops significant ankylosis resulting in mobility…
Abstract Number: 2100 • 2014 ACR/ARHP Annual Meeting
Activation of NFkβ Pathways in Sjögren’s Syndrome Related Lymphomagenesis-Role of the His159Tyr Mutation of the BAFF-R Receptor
Clio Mavragani¹, Adrianos Nezos², Aristea Papageorgiou³, Haralampos M. Moutsopoulos³, Athanasios G. Tzioufas⁴ and Michael Voulgarelis³, ¹Department of Physiology, School of Medicine, University of Athens, Athens, Greece, ²Department of Physiology, School of Medicine, University of Athens, Athens, Greece, ³Department of Pathophysiology, School of Medicine, University of Athens, Athens, Greece, ⁴Pathophysiology, School of Medicine, National University of Athens, Athens, Greece
Background/Purpose: Sjögren’s Syndrome (SS) bears the highest risk for lymphoma development among all autoimmune diseases. A growing body of evidence suggests activation of NFκB pathways…

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