Abstract Number: 2857 • 2013 ACR/ARHP Annual Meeting
The Role Of FAM173b As a Newly Identified Regulator Of Chronic Pain
Background/Purpose: Chronic pain is a major debilitating problem in many inflammatory diseases including rheumatoid arthritis and osteoarthritis. Pain is an important problem during active disease…Abstract Number: 2816 • 2013 ACR/ARHP Annual Meeting
Pilot Phase Outcomes From The ACR/Carra Inter-Institutional Mentoring Program In Pediatric Rheumatology
Background/Purpose: In pediatric rheumatology, the small size of many academic programs translates into limited mentoring options for early career physicians. To address this “mentorship gap,”…Abstract Number: 2817 • 2013 ACR/ARHP Annual Meeting
Objective Assessment Of Musculoskeletal Physical Examination Skills During Continuing Education Programs For Primary Care Providers Adds Significant Information Not Obtained Through Self-Assessment
Background/Purpose: Self-assessment is the most frequently used method in the evaluation of continuing medical education (CME) programs. This multi-institutional project was designed to examine convergent validity…Abstract Number: 2819 • 2013 ACR/ARHP Annual Meeting
Administration Of a Multi-Epitope Citrullinated Peptide Attuneuates adjuvant Induced Arthritis In Rats Via Induction Of Immune Tolerance
Background/Purpose: Antigen-induced peripheral tolerance is a potentially efficient and specific therapeutic approach to attenuate autoimmunity. Citrullinated peptides are major targets of disease-specific autoantibodies in Rheumatoid…Abstract Number: 2820 • 2013 ACR/ARHP Annual Meeting
Disease-Regulated Local Interleukin-10 Gene Therapy Diminishes Synovitis and Articular Cartilage Damage In Experimental Arthritis
Background/Purpose: Rheumatoid arthritis (RA) is a chronic destructive autoimmune disease and in most patients the disease follows an intermittent course with periods of exacerbation and…Abstract Number: 2821 • 2013 ACR/ARHP Annual Meeting
Evaluation Of Selective Manipulation Of The CD28 Co-Stimulation Pathway In The Rhesus Monkey Model Of Collagen-Induced Arthritis
Background/Purpose: T-cells are important in the pathogenesis of rheumatoid arthritis (RA). T-cell activation depends on at least two signals. Next to the first signal that…Abstract Number: 2822 • 2013 ACR/ARHP Annual Meeting
IKKε Deficiency Prolongs Neutrophil Survival Paradoxically Prolonging Inflammation In The Absence Of a Type I Interferon Response
Background/Purpose: Deficiency of the IKK-related kinases IKKε synergizes with the anti-inflammatory effects of IFNß in a murine model of arthritis., and this effect is mediated…Abstract Number: 2823 • 2013 ACR/ARHP Annual Meeting
FLIP Deficiency In Dendritic Cells Promotes Spontaneous Inflammatory and Erosive Arthritis
Background/Purpose: FLIP is an anti-apoptotic protein induced by chronic inflammation. In this study a mouse line with FLIP deleted in CD11c+ dendritic cells (DCs), that…Abstract Number: 2824 • 2013 ACR/ARHP Annual Meeting
Urinary Microalbumin Is Associated With Arterial Stiffness In Patients With Rheumatoid Arthritis
Background/Purpose: Rheumatoid arthritis (RA) is associated with an increased risk for cardiovascular disease (CVD). Urinary microalbumin is a risk factor for CVD in the general…Abstract Number: 2825 • 2013 ACR/ARHP Annual Meeting
The Influence Of Early Menopause On Cardiovascular Risk In Women With Rheumatoid Arthritis
Background/Purpose: Lifetime exposure to female sex hormones may play a role in the development and severity of rheumatoid arthritis (RA). These same hormones have also…Abstract Number: 2826 • 2013 ACR/ARHP Annual Meeting
Performance Of Five Current Risk Algorithms In Predicting Cardiovascular Events In Rheumatoid Arthritis Patients
Background/Purpose: Cardiovascular risk in rheumatoid arthritis (RA) is increased. The cardiovascular (CV) risk algorithms used in the general population may underestimate the risk of cardiovascular…Abstract Number: 2827 • 2013 ACR/ARHP Annual Meeting
Effect Of Biologic Agents On Lipids and Cardiovascular Risk In Rheumatoid Arthritis Patients
Background/Purpose: The risk for cardiovascular disease (CVD) is increased in patients (pts) with RA. The interplay between traditional CV risk factors and inflammatory burden may…Abstract Number: 2828 • 2013 ACR/ARHP Annual Meeting
The Performance Of The Original and An Updated Cardiovascular Risk Algorithm (SCORE) In Patients With Rheumatoid Arthritis
Background/Purpose: Cardiovascular (CV) risk in rheumatoid arthritis (RA) is increased. The CV risk algorithms for the general population may underestimate the risk of cardiovascular disease…Abstract Number: 2829 • 2013 ACR/ARHP Annual Meeting
Statin Adherence and Risk Of Mortality In Patients With Rheumatoid Arthritis: A Population-Based Study
Background/Purpose: Poor adherence with statin therapy is associated with increased mortality in the general population, but no corresponding data are available among patients with rheumatoid…Abstract Number: 2830 • 2013 ACR/ARHP Annual Meeting
First Stage Of a Simon’s Two-Stage Optimal Approach Supports Placental Transfer Of Hydroxychloroquine and a Reduced Recurrence Rate Of The Cardiac Manifestations Of Neonatal Lupus
Background/Purpose: A previous case control study suggested that hydroxychloroquine (HCQ) might prevent the development of cardiac Neonatal Lupus (cardiac NL) in anti-SSA/Ro antibody (ab) exposed…