Abstracts Archive - Page 2053 of 2607 - ACR Meeting Abstracts

Abstract Number: 2721 • 2014 ACR/ARHP Annual Meeting
Patients’ Perspective of Skin Involvement in Systemic Sclerosis
Ada Man¹, Amy Wu¹, Jessica Ziemek², Romy Christmann¹, Robert W. Simms¹, David T. Felson³ and Robert Lafyatis⁴, ¹Rheumatology, Boston University School of Medicine, Boston, MA, ²Rheumatology/Arthritis Center, Boston University School of Medicine, Boston, MA, ³Boston University School of Medicine, Boston, MA, ⁴Arthritis Center, Boston University, Boston, MA
Background/Purpose: Skin tightness and other abnormalities of the skin are the hallmark features of systemic sclerosis (SSc). While skin involvement may significantly impact a…
Abstract Number: 2720 • 2014 ACR/ARHP Annual Meeting
Prevalence and Features of Metabolic Syndrome in Systemic Sclerosis
Tiago N. Amaral¹, Karina Pereira², Nailu A. Sinicato³, Sandra Gasparini⁴, Fernando Augusto Peres³, Maria Carolina de Souza⁴, Ana Paula del Rio⁴, João Francisco Marques-Neto⁵ and Simone Appenzeller⁶, ¹Faculty of Medical Science, State University of Campinas, Campinas, Brazil, ²State University of Campinas, Limeira, Brazil, ³Medicine, State University of Campinas, Campinas, Brazil, ⁴State University of Campinas, Campinas, Brazil, ⁵University of Campinas, Campinas, Brazil, ⁶Medicine, Faculty of Medical Science, State University of Campinas Unicamp, São Paulo, Brazil
Background/Purpose: Systemic sclerosis (SSc) is a multisystem autoimmune disease characterized by initial vascular injuries and resulted fibrosis of skin and internal organs. Vascular impairment in…
Abstract Number: 2719 • 2014 ACR/ARHP Annual Meeting
Performance of the New ACR Criteria in Systemic Sclerosis: A Multicenter Study
Necati Cakir¹, Omer Nuri Pamuk² and Mehmet Ali Balci², ¹Fatih Sultan Mehmet State Hospital, Istanbul, Turkey, ²Rheumatology, Trakya University Medical Faculty, Edirne, Turkey
Background/Purpose Reliable and validated classification criteria are needed to conduct high quality clinical research in systemic sclerosis (SSc). The most widely used classification criteria for…
Abstract Number: 2718 • 2014 ACR/ARHP Annual Meeting
The UCLA Gastrointestinal Tract Questionnaire (GIT)2.0 and GI Visual Analogue Scale(GI-VAS) Reflect Different Aspects of GI Involvement in Systemic Sclerosis
Yossra Suliman^1,2, Yasser Shaweesh³, Suzanne Kafaja^4,5,6, Lewei Duan⁷ and Daniel E. Furst⁸, ¹Division of Rheumatology, Department of Medicine., David Geffen School of Medicine, University of California Los Angeles,, Los Angeles, CA, ²Rheumatology and Rehabilitation department, Faculty of Medicine, Assiut university, Assiut, Egypt, ³Division of Rheumatology, Department of Medicine., David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, ⁴Rheumatology, University of California Los Angeles, Los Angeles, CA, ⁵Medicine, University of California, Los Angeles, Department of Medicine, Los Angeles, CA, ⁶David Geffen School of Medicine, UCLA, Los Angeles, CA, ⁷David Geffen School of Medicine, University of California School of Medicine, Los Angeles, CA, ⁸University of California at Los Angeles, Los Angeles, CA
Background/Purpose UCLA GIT2.0 is a validated measure for assessing the severity of gastrointestinal involvement in systemic sclerosis patients (SSc) patients; GI VAS is also a…
Abstract Number: 2717 • 2014 ACR/ARHP Annual Meeting
Comparison of PROMIS^® survey Between Scleroderma Patients in an Academic Center and Patient-Based Scleroderma Foundations
Vivek Nagaraja¹, Veronica Berrocal², Kerri Connolly³, Ann Kennedy⁴, Daniela Seelmann⁵ and Dinesh Khanna¹, ¹Division of Rheumatology, University of Michigan, Ann Arbor, MI, ²Department of Biostatistics- School of Public Health, University of Michigan, Ann Arbor, MI, ³Scleroderma Foundation, Boston, MA, ⁴Federation of European Scleroderma Associations, Tournai, Belgium, ⁵Universidad de Los Andes, Santiago, Chile
Background/Purpose The National Institutes of Health Patient-Reported Outcomes Measurement Information System (PROMIS®) roadmap initiative is a cooperative research program designed to develop, evaluate, and standardize…
Abstract Number: 2716 • 2014 ACR/ARHP Annual Meeting
Development of a “Renal Crisis Prevention Card” As an Educational Tool Aimed at Improving Outcomes in High-Risk Patients with Systemic Sclerosis
Lee S. Shapiro^1,2,3, Lesley Ann Saketkoo⁴, Jessica F. Farrell^2,3,5 and Kim Fligelstone⁶, ¹Albany Medical College, Albany, NY, ²Steffens Scleroderma Center, Saratoga Springs, NY, ³The Center for Rheumatology, Albany, NY, ⁴Scleroderma and Sarcoidosis Patient Care and Research Center, Rheumatology and Pulmonary Medicine, Louisiana State University Health Sciences Center, New Orleans, LA, ⁵Pharmacy Practice, Albany College of Pharmacy & Health Sciences, Albany, NY, ⁶Royal Free Hospital, Scleroderma Unit and Scleroderma Society, London, United Kingdom
Background/Purpose: Scleroderma renal crisis (SRC) is a devastating complication of SSc. The introduction of effective treatment with ACE inhibition (ACE-I) in 1979 dramatically reduced…
Abstract Number: 2715 • 2014 ACR/ARHP Annual Meeting
Reliability and Validity of the Duruöz Hand Index in an Argentinian Population with Scleroderma
Vanesa Duarte¹, Gloria Crespo¹, Maritza Manzano¹, María Victoria Martire², Santiago Scarafia¹, Lucila Marino³, Felix Romanini¹, Marta Mamani¹ and Anastasia Secco¹, ¹Rheumatology, Hospital Bernardino Rivadavia, Buenos Aires, Argentina, ²Reumatología, Hospital Bernardino Rivadavia, Buenos Aires, Argentina, ³Rheumathology, Hospital Bernardino Rivadavia, Buenos Aires, Argentina
Background/Purpose: The Duruöz Hand Index (DIH) is a reliable tool for the evaluation of hand´s function in patients with scleroderma. The aim of our study…
Abstract Number: 2714 • 2014 ACR/ARHP Annual Meeting
Application of the 2013 ACR/EULAR Classification Criteria for Systemic Sclerosis in Korean Patients with Raynaud Phenomenon
Jin Su Park¹, Hee-Jin Park¹, You Jung Ha², Yong-Beom Park³, Soo-Kon Lee¹ and Sang-Won Lee⁴, ¹Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea, ²Yonsei University College of Medicine, Seoul, South Korea, ³Division of Rheumatology, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, South Korea, ⁴Department of Internal Medicine, Yonsei University College of Medicine, Seoul, NV, South Korea
Background/Purpose : The American College of Rheumatology (ACR) and the European League Against Rheumatism (EULAR) suggested the 2013 ACR/EULAR classification criteria for systemic sclerosis (SSc),…
Abstract Number: 2733 • 2014 ACR/ARHP Annual Meeting
Decreased CXCR3+CCR4-CCR6+ CD4+ Effector Memory T Cells in Patients with Granulomatosis with Polyangiitis
Lucas L. Lintermans¹, Coen A. Stegeman², Abraham Rutgers¹, Peter Heeringa³ and Wayel H. Abdulahad¹, ¹Rheumatology and Clinical Immunology, University Medical Center Groningen, Groningen, Netherlands, ²Nephrology, University Medical Center Groningen, Groningen, Netherlands, ³Pathology and Medical Biology, University Medical Center Groningen, Groningen, Netherlands
Background/Purpose: Persistent expansion of circulating CD4+ effector memory T cells (TEM) in patients with Granulomatosis with polyangiits (GPA) suggest their fundamental role in disease pathogenesis.…
Abstract Number: 2697 • 2014 ACR/ARHP Annual Meeting
Gender Disparities in Lung Transplantation in Patients with Systemic Sclerosis-Related Interstitial Lung Disease and Pulmonary Hypertension
Elizabeth Volkmann¹, Daniel E. Furst², Rajeev Saggar³, Philip J. Clements⁴, Bryant Torres⁵, Lynne Yoder¹ and Rajan Saggar¹, ¹Medicine, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA, ²University of California, Los Angeles, CA, ³Cardiothoracic Surgery, University of Arizona College of Medicine, Phoenix, AZ, ⁴University of California, Los Angeles, Department of Medicine, Los Angeles, CA, ⁵Health Policy and Management, Rollins School of Public Health, Emory University, Atlanta, GA
Background/Purpose: Lung transplantation is often the most viable option for patients with severe systemic sclerosis (SSc)-associated interstitial lung disease (ILD) that is unresponsive to pharmacologic…
Abstract Number: 2696 • 2014 ACR/ARHP Annual Meeting
Relationship Between Soluble sCD23 and B Cell Activation Factor in Patients with Systemic Lupus Erythematosus before and after Rituximab
Laura Heretiu^1,2, Maria J. Leandro³, Venkat Reddy⁴, David A. Isenberg⁵ and Geraldine Cambridge³, ¹Medicine, Centre for Rheumatology, University College London, London, United Kingdom, ²Rheumatology and Internal Medicine, 'Sf. Maria' Clinical Hospital, Bucharest, Romania, ³Centre for Rheumatology, Department of Medicine, University College London, London, United Kingdom, ⁴Centre for Rheumatology Research, Division of Medicine, University College London, London, United Kingdom, ⁵Centre for Rheumatology Research, Rayne Building, 4th Floor, Centre for Rheumatology, Department of Medicine, University College London, London, United Kingdom
Background/Purpose CD23 is the low-affinity receptor for IgE (FceRII). The soluble form, sCD23 is released into the circulation and in vitro this is consistent with…
Abstract Number: 2695 • 2014 ACR/ARHP Annual Meeting
Alterations in B Cell Subsets and BAFF Levels in Autoimmune Rheumatic Diseases Treated with B Cell Depletion Therapy: Rituximab
Pamela M.K Lutalo¹, David P. D'Cruz² and Jo Spencer³, ¹Peter Gorer Department of Immunobiology, King's College London School of Medicine, London, United Kingdom, ²Louise Coote Lupus Unit, Guy's and St Thomas' Hospital NHS Foundation Trust, London, United Kingdom, ³Peter Gorer Department of Immunobiology, King's College London, School of Medicine, London, United Kingdom
Background/Purpose: Systemic lupus erythematosus (SLE) and granulomatosis with polyangiitis (GPA) are autoimmune diseases which develop secondary to immune self-tolerance failure. Both diseases are characterised in…
Abstract Number: 2694 • 2014 ACR/ARHP Annual Meeting
B Lymphocyte Stimulator (BLyS) Promotes Dysregulated Monocyte Function in Systemic Lupus Erythematosus(SLE)
Eoghan M. McCarthy¹, Joan Ní Gabhann², Siobhán Smith², Lorraine O' Neill³, Eamonn S. Molloy⁴, Donough Howard¹, Paul G. O'Connell¹, S. Donnelly⁵, Grainne M. Kearns⁶ and Caroline Jefferies², ¹Rheumatology, Beaumont Hospital, Dublin, Ireland, ²Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland, ³Rheumatology, Dublin Academic Medical Centre, St. Vincent's University Hospital, Dublin, Ireland, ⁴Rheumatology, St. Vincent's University Hospital, Dublin 4, Ireland, ⁵Rheumatology, Mater Misericordiae University Hospital, Dublin 7, Ireland, ⁶Rheumatology Department, Beaumont Hospital, Dublin, Ireland
Background/Purpose SLE involves complex interactions between the innate and adaptive immune systems. Monocytes are increasingly recognised to play a key role in the dysregulated immune…
Abstract Number: 2713 • 2014 ACR/ARHP Annual Meeting
The Relationship of Patient Reported Skin Symptoms to the Scleroderma HAQ, the Modified Rodnan Skin Score and Skin Pathology.
Jessica Ziemek¹, Ada Man², Robert W. Simms² and Robert Lafyatis², ¹Rheumatology/Arthritis Center, Boston University School of Medicine, Boston, MA, ²Rheumatology, Boston University School of Medicine, Boston, MA
Background/Purpose: Changes in skin are a cardinal feature of systemic sclerosis (SSc). However, there are no SSc specific patient reported outcome measures validated for use…
Abstract Number: 2712 • 2014 ACR/ARHP Annual Meeting
Nailfold Videocapillaroscopy in Healthy Children and Adolescents: Description of Patterns of Normality
Daniela Piotto¹, Juliana Sekiyama², Cristiane Kayser³, Mariana Yamada⁴, Claudio A. Len⁵ and Maria Teresa Terreri⁶, ¹Universidade Federal de São Paulo/UNIFESP, Assistant Doctor, Universidade Federal de São Paulo/UNIFESP, São Paulo, Brazil, ²Universidade Estadual de Campinas, Campinas, Brazil, ³Rheumatology Division, Universidade Federal de São Paulo, São Paulo, Brazil, ⁴Universidade Federal de São Paulo, Pediatric Resident, São Paulo, Brazil, ⁵Universidade Federal de São Paulo/Escola Paulista de Medicina, São Paulo, Brazil, ⁶Universidade Federal de São Paulo/UNIFESP, São Paulo, Brazil
Background/Purpose Video capillaroscopy (VCP) allows for the evaluation of capillary dimensions and to quantify the degree of microangiopathic alterations in autoimmune diseases. However, studies in…

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