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  • Abstract Number: 2760 • 2014 ACR/ARHP Annual Meeting

    Interferon Alfa-Associated Depression in Patients with Behçet’s Syndrome

    Yasin Keskin1, Emire Seyahi2, Cagri Poyraz3, Serdal Ugurlu1, Yilmaz Ozyazgan4 and Hasan Yazici5, 1Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey, 2Division of Rheumatology,Department of Medicine, Cerrahpasa Medical Faculty, University of Istanbul, Istanbul, Turkey, 3Department of Psychiatry, Cerrahpasa Medical Faculty, University Of Istanbul, Istanbul, Istanbul, Turkey, 4Department of Ophthalmology, Cerrahpasa Medical Faculty University of Istanbul, Istanbul, Turkey, 5Istanbul University, Cerrahpasa Medical Faculty, Rheumatology, Istanbul, Turkey

    Background/Purpose: Interferon (IFN) is an effective immune-modulatory agent in the medical management of eye disease of Behçet’s syndrome (BS). The agent is frequently associated with…
  • Abstract Number: 2761 • 2014 ACR/ARHP Annual Meeting

    Increased Risk of Parenchymal Neurological Involvement in Behcet’s Syndrome Patients with Panuveitis

    Berivan Bitik1, Berna Goker2, Kubilay Sahin3, Yesim Sucullu Karadag4, Ridvan Mercan5, Abdurrahman Tufan1, Mehmet Akif Ozturk1, Fikri Ak4, Yasar Karaaslan6,7 and Seminur Haznedaroglu1, 1Internal Medicine-Rheumatology, Gazi University School of Medicine, Ankara, Turkey, 2Department of Internal Medicine- Rheumatology, Gazi University School of Medicine, Ankara, Turkey, 3Rheumatology, Ankara Numune Education and Research Hospital, Ankara, Turkey, 4Neurology, Ankara Numune Education and Research Hospital, Ankara, Turkey, 5Gazi University School of Medicine, Ankara, Turkey, 6Rheumatology, Hitit University, Corum, Turkey, 7Ankara Numune Training and Research Hospital, Ankara, Turkey

    Background/Purpose Behcet’s Syndrome (BS) is a systemic vasculitis which may involve multiple organ systems simultaneously. Most frequently, clinical findings in BS fit into well recognized…
  • Abstract Number: 2762 • 2014 ACR/ARHP Annual Meeting

    Atrophy of Hippocampal Region in Chronic Progressive Neuro-Behçet’s Disease

    Hirotoshi Kikuchi1, Kurumi Asako1, Maki Takayama1, Yoshitaka Kimura1, Akiko Okamoto1, Toshihiro Nanki1,2, Hajime Kono1 and Shunsei Hirohata3, 1Department of Internal Medicine, Teikyo University School of Medicine, Tokyo, Japan, 2Department of Clinical Research Medicine, Teikyo University, Tokyo, Japan, 3Int Med/Rheumatol & Infec Dis, Kitasato University School of Medicine, Sagamihara, Japan

    Background/Purpose: Central nervous system involvement in Behçet's disease, usually called neuro-Behçet's disease (NB), can be classified into acute NB (ANB) and chronic progressive NB (CPNB)…
  • Abstract Number: 2763 • 2014 ACR/ARHP Annual Meeting

    Long-Term Outcome of Chronic Progressive Neurological Manifestations in Behcet’s Disease

    Shunsei Hirohata1, Hirotoshi Kikuchi2, Tetsuji Sawada3, Hiroko Nagafuchi4, Msataka Kuwana5, Mitsuhiro Takeno6 and Yoshiaki Ishigatsubo7, 1Int Med/Rheumatol & Infec Dis, Kitasato Univ School of Med, Kanagawa, Japan, 2Department of Internal Medicine, Teikyo University School of Medicine, Tokyo, Japan, 3Internal Medicine 3, Tokyo Medical University, Tokyo, Japan, 4Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Kanagawa, Japan, 5Internal Medicine, Keio University School of Medicine, Tokyo, Japan, 6Clinical Laboratory Department, Yokohama City University Hospital, Yokohama, Japan, 7Int Med & Clin Immunology, Yokohama City Grad Schl of Med, Yokohama, Japan

    Background/Purpose: Chronic progressive neurological manifestations in Behcet's disease (BD) is characterized by progressive deterioration leading to disability either with or without a history of previous…
  • Abstract Number: 2764 • 2014 ACR/ARHP Annual Meeting

    S100B Astrocyte Protein May Serve As a Prognostic Factor in Reversible Cerebral Vasoconstrictive Syndromes

    Juan J. Maya1, Vikram Puvenna2,3,4, Chanda Brennan2,3,5, Seby John6, Ken Uchino7, Leonard H. Calabrese8, Damir Janigro2,4,9,10 and Rula Hajj-Ali11, 1Internal Medicine, Cleveland Clinic Foundation, Cleveland, OH, 2Cerebrovascular Research, Cleveland Clinic Lerner College of Medicine, Cleveland, OH, 3Neurosurgery, Cleveland Clinic Lerner College of Medicine, Cleveland, OH, 4Cleveland Clinic Lerner College of Medicine, Cleveland, OH, 5Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Cleveland, OH, 69500 Euclid Avenue S10-C, Cleveland Clinic Foundation, Cleveland, OH, 7Neurology, Cleveland Clinic Foundation, Cleveland, OH, 8Cleveland Clinic Foundation, Cleveland, OH, 9Department of Neurosurgery, Cleveland Clinic Lerner College of Medicine, Cleveland, OH, 10Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Cleveland, OH, 11Rheumatology, Cleveland Clinic Foundation, Cleveland, OH

    Background/Purpose: Reversible Cerebral Vasoconstriction Syndromes (RCVS) are a group of disorders characterized by acute onset of recurrent thunderclap headaches with or without neurologic deficits. Radiologically,…
  • Abstract Number: 2765 • 2014 ACR/ARHP Annual Meeting

    Putative Blood Biomarkers of Reversible Cerebral Vasoconstriction Syndrome  

    Seby John1, Belinda Willard2, Leonard H. Calabrese2, Ken Uchino3, Tariq Hammad2, Stewart Tepper2, Mark Stillman2 and Rula A Hajj-Ali4, 19500 Euclid Avenue S10-C, Cleveland Clinic Foundation, Cleveland, OH, 2Cleveland Clinic Foundation, Cleveland, OH, 3Neurology, Cleveland Clinic Foundation, Cleveland, OH, 4Rheumatology, Cleveland Clinic Foundation, Cleveland, OH

     Putative blood biomarkers of Reversible Cerebral Vasoconstriction Syndrome Background/Purpose The pathophysiology and molecular mechanisms of Reversible Cerebral Vasoconstriction Syndrome (RCVS) are unknown. Objective of the…
  • Abstract Number: 2766 • 2014 ACR/ARHP Annual Meeting

    Mycophenolate Mofetil in the Treatment of Primary  Central  Nervous  System  Vasculitis

    Carlo Salvarani1, Robert D. Brown Jr.2, Teresa J. H. Christianson2, John Huston III2, Francesco Muratore1, Caterina Giannini2 and Gene G. Hunder3, 1Rheumatology Unit, Arcispedale S Maria Nuova, Reggio Emilia, Italy, 2Mayo Clinic, Rochester, MN, 3Rheumatology, Mayo Clinic, Rochester, MN

    Background/Purpose .  The optimal management  of primary central nervous system vasculitis (PCNSV) remains unclear.   Cyclophosphamyde (CYC) in combination with glucocorticoids (GCs) or GCs alone are…
  • Abstract Number: 2767 • 2014 ACR/ARHP Annual Meeting

    Core Outcome Domains and Potential Measurement Instruments in  polymyalgia Rheumatica (PMR) Using Omeract Filter 2.0

    Sarah Mackie1, Toby Helliwell2, Rodney Hughes3, E Brouwer4, Colin T. Pease5, Christian Mallen6, Maarten Boers7 and John R. Kirwan8, 1NIHR-Leeds Musculoskeletal Biomedical Research Unit, University of Leeds, Leeds, United Kingdom, 2Primary Care and Health Sciences, Keele University, Staffordshire, United Kingdom, 3Rheumatology, St. Peters Hospital, Chertsey Surrey, United Kingdom, 4Rheumatology and Clinical Immunology, University Medical Center Groningen, Groningen, Netherlands, 5Department of Rheumatology, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, 6Research Institute for Primary Care and Health Sciences, Keele University, Keele, United Kingdom, 7Epidemiology & Biostatistics, VU University Medical Center, Amsterdam, Netherlands, 8Academic Rheumatology Unit, Bristol Royal Infirmary, Bristol, United Kingdom

    Background/Purpose The OMERACT PMR specialist interest group was established to develop a core outcome measurement set for PMR using the methods of OMERACT filter 2.0.…
  • Abstract Number: 2768 • 2014 ACR/ARHP Annual Meeting

    Patient Reported Outcomes and Acute Phase Reactants in  Polymyalgia Rheumatica in Patients Treated with Prednisone Versus Modified-Release Prednisone

    Mauro Betelli, Giulia Erba, Massimo Ricci, Carlo Valena, Elisabetta Allevi, Marta Riva, Giorgia Grosso, Simona Barbarossa, Federica Bonomi and Maria Rosa Pozzi, Department of Internal Medicine, Rheumatology Outpatient Clinic - San Gerardo Hospital – Milano-Bicocca University, Monza, Italy

    Background/Purpose Polymyalgia rheumatica (PMR) is a chronic inflammatory disorder of the elderly, characterised by morning stiffness, pain and aching in the hip and shoulder girdles…
  • Abstract Number: 2769 • 2014 ACR/ARHP Annual Meeting

    Validation of New 2012 EULAR/ACR Classification Criteria for Polymyalgia Rheumatica: Comparison with the Previous Criteria in a Prospective Multi-Center Study

    Gulsen Ozen1, Seda Bas2, Ali Ugur Unal2, Gezmis Kimyon3, Ahmet Mesut Onat4, Meryem Can5, Alperen Mengi5, Ali Sahin6, Sema Yilmaz7, Havva Keskin8, Sadiye Murat8, Ayse Balkarli9, Veli Cobankara9, Omer Nuri Pamuk10, Yonca Cagatay11, Neslihan Yilmaz11, Ilker Yagci12, Pamir Atagunduz2, Sibel Z. Aydin13, Nevsun Inanc2 and Haner Direskeneli2, 1Rheumatology, Marmara University School of Medicine, Istanbul, Turkey, 2Department of Rheumatology, Marmara University School of Medicine, Istanbul, Turkey, 3Department of Rheumatology, Gaziantep University School of Medicine, Gaziantep, Turkey, 4Rheumatology, Gaziantep University School of Medicine, Gaziantep, Turkey, 5Department of Rheumatology, Fatih Sultan Mehmet Education and Research Hospital, Istanbul, Turkey, 6Department of Rheumatology, Cumhuriyet University Faculty of Medicine, Sivas, Turkey, 7Department of Rheumatology, Selcuk University School of Medicine, Konya, Turkey, 8Department of Physical Medicine and Rehabilitation, Goztepe Medeniyet University Faculty of Medicine, Istanbul, Turkey, 9Department of Rheumatology, Pamukkale University School of Medicine, Denizli, Turkey, 10Department of Rheumatology, Trakya University School of Medicine, Edirne, Turkey, 11Department of Rheumatology, Bilim University Faculty of Medicine, Istanbul, Turkey, 12Department of Physical Medicine and Rehabilitation, Marmara University School of Medicine, Istanbul, Turkey, 13Department of Rheumatology, Koc University Faculty of Medicine, Istanbul, Turkey

    Background/Purpose: To evaluate the diagnostic and discriminative ability of the new 2012 European League Against Rheumatism (EULAR)/American College of Rheumatology (ACR) polymyalgia rheumatica (PMR) classification…
  • Abstract Number: 2770 • 2014 ACR/ARHP Annual Meeting

    Polymyalgia Rheumatica Relapse and “Silence” Large Vessel Vasculitis. Is There Any Association?

    Stavros Chrysidis1, Philip Rask Lage-Hansen1 and Andreas P. Diamantopoulos2, 1Department of Rheumatology, Hospital of Southwest Denmark, Esbjerg, Denmark, 2Rheumatology, Hospital of Southern Norway Trust, Kristiansand, Norway

    Background/Purpose Large Vessel Vasculitis (LVV) can present with heterogeneous clinical manifestations, which range from general symptoms (fever, loss of weight) to the classic symptoms of …
  • Abstract Number: 2771 • 2014 ACR/ARHP Annual Meeting

    PET-CT Imaging and Association of Ferritin Autoantibodies in Polymyalgia Rheumatica

    Niklas Thomas Baerlecken1, Torsten Witte2, Marco Amedeo Cimmino3 and Dario Camellino4, 1Clinical Immunology and Rheumatology, MD, Hannover, Germany, 2Medical School Hannover, MD, Hanover, Germany, 3Clinica Reumatologica, Università di Genova, Genova, Italy, 4Dipartimento Medicina Interna, Clinica Reumatologica, Genova, Italy

    Background/Purpose Previously we described antibodies against ferritin heavy chain peptide (anti-FHCP) in sera of patients with giant cell arteritis (GCA) and/or polymyalgia rheumatic (PMR) before…
  • Abstract Number: 2772 • 2014 ACR/ARHP Annual Meeting

    The Use of Imaging in the Diagnosis of Polymyalgia Rheumatica: Systematic Literature Review and Meta-Analysis

    Sarah Mackie1, Gouri Koduri2, Catherine L. Hill3,4, Andrew Hutchings5, Richard J. Wakefield6, Bhaskar Dasgupta7 and Jeremy Wyatt8, 1NIHR-Leeds Musculoskeletal Biomedical Research Unit, University of Leeds, Leeds, United Kingdom, 2Rheumatology, York Teaching Hospital NHS Foundation Trust, York, United Kingdom, 3Rheumatology Unit, The Queen Elizabeth Hospital, Woodville, Australia, 4Discipline of Medicine, University of Adelaide, Adelaide, Australia, 5Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, United Kingdom, 6NIHR-Leeds Musculoskeletal Biomedical Research Unit and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 7Department of Rheumatology, Southend University Hospital, Essex, United Kingdom, 8Leeds Insitute of Health Sciences, University of Leeds, Leeds, United Kingdom

    Background/Purpose ACR/EULAR provisional classification criteria for polymyalgia rheumatica (PMR) incorporate musculoskeletal ultrasound of shoulder and hip (bursitis and synovitis given equal weight). Our objective was…
  • Abstract Number: 2773 • 2014 ACR/ARHP Annual Meeting

    Whole-Body MRI Reveals Characteristic Extracapsular Pattern of Inflammation in Polymyalgia Rheumatica

    Sarah Mackie1, Colin T. Pease2, Eiki Fukuba3, Paul Emery4, Richard J. Hodgson4, Jane E. Freeston5 and Dennis McGonagle6, 1NIHR-Leeds Musculoskeletal Biomedical Research Unit, University of Leeds, Leeds, United Kingdom, 2Department of Rheumatology, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, 3Department of Radiology, Faculty of Medicine, Shimane University, Shimane, Japan, 4NIHR-Leeds Musculoskeletal Biomedical Research Unit and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 5NIHR-Leeds Musculoskeletal Biomedical Research Unit and Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds., United Kingdom, Leeds, United Kingdom, 6Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom

    Background/Purpose Polymyalgia rheumatica (PMR) is a disease of widespread musculoskeletal inflammation characterized by pain and stiffness in shoulder and hip girdles. Here we report the…
  • Abstract Number: 2736 • 2014 ACR/ARHP Annual Meeting

    Female Specific Increase in T Cell Glycosylation in Lupus

    Gabriela Gorelik1 and Bruce Richardson2, 1Internal Medicine, University of Michigan, Ann Arbor, MI, 2Rheumatology, University of Michigan, Ann Arbor, MI

    Background/Purpose: Systemic Lupus Erythematosus (SLE) is an autoimmune inflammatory disease characterized by altered T cell signaling. SLE is characterized by epigenetic mechanisms that cause hypomethylation…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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