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  • Abstract Number: 595 • 2014 ACR/ARHP Annual Meeting

    Radiographic Sacroiliitis Progression in an Early Axial Spondyloarthritis Cohort

    Concepcion Castillo-Gallego1, Jesus Sanz2, Carmen Martin-Hervas3, Mireia Moreno4, Victoria Navarro-Compán5, Diana Peiteado1, Jorge Gratacos-Masmitja6, Eugenio De Miguel7 and Emilio Martín-Mola1, 1Rheumatology, Hospital La Paz - IdiPaz, Madrid, Spain, 2Rheumatology, Hospital Puerta de Hierro Majadahonda, Madrid, Spain, 3Radiology, Hospital Universitario La Paz, Madrid, Spain, 4Rheumatology, University Hospital Parc Taulí, Sabadell, Spain, 5Rheumatology, Rheumatologist, Madrid, Spain, 6Parc Tauli, S/N, Hospital Parc Tauli, Sabadell, Spain, 7Department of Rheumatology, Hospital Universitario La Paz, Madrid, Spain

    Background/Purpose: The current concept of axial Spondyloarhtritis (axSpA) considers non-radiographic axSpA (nr-axSpA) and Ankylosing Spondylitis (AS) as two stages of one disease. There are limited…
  • Abstract Number: 594 • 2014 ACR/ARHP Annual Meeting

    Do Bone Marrow Edema Lesions in the Sacroiliac Joint Change into Fatty Lesions over a 1-Year Period in Patients with Axial Spondyloarthritis or Possible Spondyloarthritis

    Pauline Bakker1, Rosaline van den Berg2, Manouk de Hooge1, Floris van Gaalen2, Monique Reijnierse1, T.W.J. Huizinga1 and Désirée van der Heijde3, 1Leiden University Medical Center, Leiden, Netherlands, 2Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 3Rheumatology, Diakonhjemmet Hospital, Oslo, Norway

    Background/Purpose: Bone marrow edema (BME) lesions in the sacroiliac joint (SIJ) may change into fatty lesions over time. Fatty lesions are regarded as the earliest…
  • Abstract Number: 593 • 2014 ACR/ARHP Annual Meeting

    The Clinimetric Outcomes of Two Bath Ankylosing Spondyltis Metrology Indices in Treatment with TNF-á Blockers

    Eon Jeong Nam1, Jeong Soo Eun2, Sang Hoon Kwon3 and Young Mo Kang4, 1Division of Rheumatology, Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, South Korea, 2Internal Medicine (Rheumatology), Kyungpook National University School of Medicine, Daegu, South Korea, 3Internal medicine (Rheumatology), Kyungpook National University School of Medicine, Daegu, South Korea, 4Dept of Internal Medicine, Kyungpook National Univ Hosp, Daegu, South Korea

    Background/Purpose Bath Ankylosing Spondyltis Metrology Index (BASMI) was developed to quantify the accurate axial status and to assess the clinical changes in spinal movement. The…
  • Abstract Number: 592 • 2014 ACR/ARHP Annual Meeting

    Clinical and Psychological Correlates of Sleep Difficulties in Patients with Spondyloarthropathies Compared to Patients with Rheumatoid Arthritis

    Konstantinos Kotsis1, Thomas Hyphantis2, Paraskevi V. Voulgari3, Andre F. Carvalho4 and Alexandros A. Drosos5, 1Department of Psychiatry, Medical School, University of Ioannina, 45110, Ioannina, Greece., Department of Psychiatry, Medical School, University of Ioannina, 45110, Ioannina, Greece., Ioannina, Greece, 2Department of Psychiatry, Medical School, University of Ioannina, Ioannina 45110, Greece., Department of Psychiatry, Medical School, University of Ioannina, Ioannina 45110, Greece., Ioannina, Greece, 3Rheumatology Clinic, Department of Internal Medicine, Medical School, University of Ioannina, 45110, Associate Professor of Rheumatology, Ioannina, Greece, 4Department of Clinical Medicine, Faculty of Medicine, Federal University of Ceará, Fortaleza, Ceará, Brazil., Department of Clinical Medicine, Faculty of Medicine, Federal University of Ceará, Fortaleza, Ceará, Brazil., Fortaleza, Brazil, 5Rheumatology Clinic, Department of Internal Medicine, University of Ioannina, Ioannina, Greece

    Background/Purpose Sleep difficulties are common in patients with rheumatological disorders. Patients with Rheumatoid Arthritis (RA) report frequently poor quality sleep, numerous night awakening and difficulty…
  • Abstract Number: 591 • 2014 ACR/ARHP Annual Meeting

    The Fat Spondyloarthritis Spine Score (FASSS) Independently Predicts Radiographic Progression in Patients with Ankylosing Spondylitis

    Susanne Juhl Pedersen1, Stephanie Wichuk2, Praveena Chiowchanwisawakit3, Zheng Zhao4, Robert GW Lambert5 and Walter P. Maksymowych6, 1Copenhagen Center for Arthritis Research, Copenhagen University Hospital at Glostrup, Copenhagen, Denmark, 2Department of Medicine, University of Alberta, Edmonton, AB, Canada, 3Mahidol University, Bangkok, Thailand, 4PLA General Hospital, Beijing, China, 5Radiology, University of Alberta, Edmonton, AB, Canada, 6Medicine/Rheumatic Dis Unit, University of Alberta, Edmonton, AB, Canada

    The Fat Spondyloarthritis Spine Score (FASSS) independently predicts radiographic progression in patients with ankylosing spondylitis.  Background/Purpose Vertebral corner fat lesions have been shown to be…
  • Abstract Number: 590 • 2014 ACR/ARHP Annual Meeting

    Factors Associated with a Poor Functional Prognosis in Early Inflammatory Back Pain: Results from the DESIR Cohort

    Cédric Lukas1, Maxime Dougados2 and Bernard Combe1, 1Immuno-Rhumatologie, Hopital Lapeyronie, Montpellier, France, 2Descartes University, Cochin Hospital, Paris, France

    Background/Purpose Spondyloarthritis is a heterogeneous disease, with various and hardly predictable potential courses. We aimed at determining prognostic factors of a bad functional outcome at…
  • Abstract Number: 589 • 2014 ACR/ARHP Annual Meeting

    Patients with Nr-Axspa Show a Statistically Higher Disease Burden in Clinical Practice Compared with Patients with Radiographic Axial Spa

    Lennart TH Jacobsson1, Tomas Husmark2, Elke Theander3, Kenneth Henriksson4, Katharina Büsch5 and Martin Johansson5, 1Department of Rheumatology and Inflammation Research, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden, 2Rheumatology, Falu Hospital, Falun, Sweden, 3Skane University Hospital Malmö, Lund University, Malmö, Sweden, 4Rheumatology city clinic, Stockholm, Sweden, Stockholm, Sweden, 5AbbVie AB, Stockholm, Sweden, Stockholm, Sweden

    Background/Purpose The ASAS axial SpA classification criteria was published in 2009 but so far there has been limited research on axial SpA patients in clinical…
  • Abstract Number: 588 • 2014 ACR/ARHP Annual Meeting

    Blacks with As Have Greater Disease Severity Than Whites

    Farokh Jamalyaria1, Michael M. Ward2, MinJae Lee3, Lianne S. Gensler4, Laura A. Diekman5, Mohammad H. Rahbar6, Amirali Tahanan6, Shervin Assassi7, Michael H. Weisman8 and John D. Reveille9,10, 1University of Texas Health Science Center at Houston, Houston, TX, 2Bldg 10 CRC Rm 4-1339, NIAMS/NIH, Bethesda, MD, 3Medicine, University of Texas Health Science Center at Houston, Houston, TX, 4Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA, 5Rheumatology, The University of Texas Health Science Center at Houston, Houston, TX, 6The University of Texas Health Science Center at Houston, Houston, TX, 7Rheumatology, University of Texas Health Science Center at Houston, Houston, TX, 8Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, 9Internal Medicine/Rheumatology, University of Texas Health Science Center at Houston, Houston, TX, 10Internal Medicine/Rheumatology, Univ of Texas Health Science Center at Houston, Houston, TX

    Background/Purpose : To compare clinical parameters in African American (AA) patients with ankylosing spondylitis (AS) to white patients. Methods: 539 AS patients (47 B, 492…
  • Abstract Number: 587 • 2014 ACR/ARHP Annual Meeting

    Clinical Characteristics of Nonradiographic Axial Spondyloarthritis in Korea: A Comparison with Ankylosing Spondylitis

    Hyungjin Kim1, Hyemin Jeong1, Seulkee Lee1, Inyoung Kim1, Jiwon Hwang2, Jaejoon Lee1, Jinseok Kim3, Eun-Mi Koh4 and Hoon-Suk Cha5, 1Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, 2Department of Medicine,Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, 31753-3, Ara-1 Dong, Jeju National University Hospital, Jeju, South Korea, 4Dept of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea, 5Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea

    Background/Purpose: To evaluate the clinical characteristics and outcomes of nonradiographic axial spondyloarthritis (nr-axSpA) in Korean patients. Methods: A retrospective analysis evaluated 155 patients with nr-axSpA…
  • Abstract Number: 586 • 2014 ACR/ARHP Annual Meeting

    Helplessness in Coping Is Associated with Worse Patient Reported Outcomes Among Patients with Ankylosing Spondylitis: A Longitudinal Multi-Country Cohort Study

    Walter P. Maksymowych1, Annelies Boonen2, Helena Marzo-Ortega3, Marina N. Magrey4, Manish Mittal5, Michael Halpern6, Jeannette Renaud6, Yanjun Bao5 and Avani D. Joshi5, 1University of Alberta, Edmonton, AB, Canada, 2Maastricht University Medical Center, Maastricht, Netherlands, 3LMBRU, Chapel Allerton Hospital, and University of Leeds, Leeds, United Kingdom, 4Department of Medicine, Division of Rheumatology, Case Western Reserve University, MetroHealth Medical Center, Cleveland, OH, 5AbbVie Inc., North Chicago, IL, 6RTI International, Washington, DC

    Background/Purpose: Ankylosing spondylitis (AS) causes pain, joint damage and reduced function, which contribute to a substantial burden on affected patients and their families. A feeling…
  • Abstract Number: 585 • 2014 ACR/ARHP Annual Meeting

    Optimism Levels Are Moderate and Similar in Patients with Axial Spondyloarthritis and Chronic Low Back Pain, and Are Related to Mental Quality of Life but Not Physical Quality of Life. a Cross Sectional Study of 277 Patients

    Sarah Kreis1,2,3, Anna Molto2,3, Florian Bailly2,3, Sabrina Dadoun2,3, Stephanie Fabre2,3,4, Christophe Hudry2, Franck Zenasni5, Sylvie Rozenberg2,3, Edouard Perthuiset4, Bruno Fautrel2,6 and Laure Gossec2,7, 1Institut de Psychologie, Laboratoire de Psychopathologie et Processus de Santé EA4057, Université Paris Descartes, Boulogne-Billancourt, France, 2Sorbonne Universités, UPMC Univ Paris 06, GRC-08, Institut Pierre Louis d’Epidémiologie et de Santé Publique, paris, France, 3Pitié-Salpêtrière Hospital, AP-HP, Rheumatology department, paris, France, 4Pontoise University Hospital, pontoise, France, 5Institut de Psychologie, Laboratoire de Psychopathologie et Processus de Santé EA4057, Université Paris Descartes, Paris, France, Boulogne-Billancourt, France, 6Rheumatology, Pitie Salpetriere Hospital, Paris, France, 7Rheumatology, Pitié-Salpêtrière Hospital, AP-HP, Paris, France

    Background/Purpose Axial Spondyloarthritis (AxSpA) and chronic low back pain (LBP) are very different chronic rheumatic diseases in terms of physiopathology and prognosis but both have…
  • Abstract Number: 583 • 2014 ACR/ARHP Annual Meeting

    What Is the Correlation of Individual HAQ and Basdai Questions with Disease Activity Measures in Ankylosing Spondylitis?  Implications for Instrument Reduction

    Proton Rahman1, Michel Zummer2, Wojciech Olszynski3, Majed Khraishi4, Dalton Sholter5, Rafat Faraawi6, William Bensen7, Milton Baker8, Andrew Chow9, Julie Vaillancourt10, John S. Sampalis10, Francois Nantel11, Allen J Lehman12, Susan Otawa12 and May Shawi11, 1Faculty of Medicine, Memorial University of Newfoundland, St. John's, NF, Canada, 2Université de Montréal, Montreal, QC, Canada, 3University of Saskatchewan, Saskatoon, SK, Canada, 4Nexus Clinical Research, St John's, NF, Canada, 5University of Alberta, Edmonton, AB, Canada, 6McMaster University, Hamilton, ON, Canada, 7Division of Rheumatology, McMaster University, Hamilton, ON, Canada, 8University of Victoria, Victoria, BC, Canada, 9University of Toronto, McMaster University, Credit Valley Rheumatology, Mississauga, ON, Canada, 10JSS Medical Research, Montreal, QC, Canada, 11Janssen Inc., Toronto, ON, Canada, 12Medical Affairs, Janssen Inc., Toronto, ON, Canada

    Background/Purpose Despite the importance of the Health Assessment Questionnaire (HAQ) and Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) in assessing patient-reported functional status and disease…
  • Abstract Number: 584 • 2014 ACR/ARHP Annual Meeting

    Flare in Spondyloarthritis: Proposal of a Meaningful Change in Symptomatic Outcome Measures in Axial Spondyloarthritis

    Maxime Dougados1, Emily Wood2, Laure Gossec3, Désirée van der Heijde4 and Isabelle Logeart5, 1Université Paris René Descartes and Hôpital Cochin, Paris, France, 2Biostatistics, Quanticate, Hitchin, England, 3Rheumatology, UPMC GRC08, Paris 06 University, Pitié Salpétrière Hospital, Paris, France, 4Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 5Pfizer, Paris, France

    Background/Purpose: Recognition of flare is important in both daily practice and clinical trial setting. However, there is no clear definition of flare in patients with…
  • Abstract Number: 582 • 2014 ACR/ARHP Annual Meeting

    Non-Steroidal Anti-Inflammatory Drugs in Axial Spondyloarthritis: A Cochrane Review

    Féline Kroon1, Lennart van der Burg1, Sofia Ramiro2, Robert Landewé3,4, Rachelle Buchbinder5 and Désirée van der Heijde6, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Clinical Immunology and Rheumatology, Amsterdam Rheumatology Center/University of Amsterdam, Amsterdam, Netherlands, 3Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands, 4Atrium Medical Center, Heerlen, Netherlands, 5Monash Department of Clinical Epidemiology at Cabrini Hospital, Department of Epidemiology and Preventive Medicine, Monash University, Malvern, Victoria, Australia, 6Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose: We performed a Cochrane systematic review to determine the benefits and harms of non-steroidal anti-inflammatory drugs (NSAIDs) in axial spondyloarthritis (axSpA). Methods: We included…
  • Abstract Number: 581 • 2014 ACR/ARHP Annual Meeting

    Evaluation of the Nonsteroidal Anti-Inflammatory Drug-Sparing Effect of Etanercept in Axial Spondyloarthritis: Results of a Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial

    Maxime Dougados1, Emily Wood2, Bernard Combe3, Corinne Miceli-Richard4, Francis Berenbaum5, Nandan Koppiker6, Arnaud Dubanchet7 and Isabelle Logeart7, 1Université Paris René Descartes and Hôpital Cochin, Paris, France, 2Biostatistics, Quanticate, Hitchin, England, 3Immuno-Rhumatologie, Hôpital Lapeyronie, Montpellier, France, 4Rheumatology Department, Université Paris-Sud 11, Bicêtre Hospital,, Kremlin Bicêtre, France, 5Service de Rhumatologie, Saint-Antoine Hospital, Paris, France, 6Pfizer PGRD, Sandwich, United Kingdom, 7Pfizer, Paris, France

    Background/Purpose Nonsteroidal anti-inflammatory drugs (NSAIDs) are first-line pharmacotherapy in axial spondyloarthritis (axSpA) but are recommended for use at the lowest effective dose for the shortest…
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