Abstract Number: 2119 • 2015 ACR/ARHP Annual Meeting
Findings and Therapeutic Impact of Magnetic Resonance Imaging (MRI) Studies for Patients with Lower Back Pain with Neurologic Symptoms. Are We Choosing Wisely?
Background/Purpose: According to different guidelines, the presence of neurological symptoms in patients with lower back pain (LBP) is a validated indication for more complex imaging…Abstract Number: 2120 • 2015 ACR/ARHP Annual Meeting
Alterations in Complement C3 and iC3b in SLE Pregnancies
Background/Purpose: Pregnancy in patients with SLE is associated with increased risk of maternal and fetal complications. Studies in experimental models and humans suggest that complement…Abstract Number: 2121 • 2015 ACR/ARHP Annual Meeting
Placentas of Lupus Pregnancies Are Characterized By Marked Inflammatory Changes Despite Good Disease Control
Background/Purpose: Systemic lupus erythematosus (SLE) is associated with increased risk of adverse pregnancy outcomes (APO), including preeclampsia and intrauterine growth restriction. While significant placental…Abstract Number: 2122 • 2015 ACR/ARHP Annual Meeting
A Novel Severity Score Based on Cardiac Neonatal Lupus Manifestations Serves As a Predictor and Outcome Measure of Morbidity in Anti-Ro Exposed Fetuses
Background/Purpose: Women with anti-Ro face a spectrum of fetal consequences when pregnant, from complete wellbeing to death from cardiac neonatal lupus (cardiac NL). Transplacental passage…Abstract Number: 2123 • 2015 ACR/ARHP Annual Meeting
Incidence and Prognosis of Neonatal and Late-Onset Dilated Cardiomyopathy Associated with Cardiac Neonatal Lupus
Background/Purpose: Dilated cardiomyopathy (DCM) is a well-known complication of cardiac neonatal lupus syndrome and is associated with a high mortality rate. Its risk factors are…Abstract Number: 2124 • 2015 ACR/ARHP Annual Meeting
Racial Disparities in Lupus Pregnancy
Background/Purpose: Both lupus and pregnancy have significant racial disparities, with black women experiencing higher rates of complication compared to other race and ethnic groups. …Abstract Number: 2125 • 2015 ACR/ARHP Annual Meeting
Rheumatic and Non-Rheumatic Autoimmune Diseases in SLE Offspring
Background/Purpose: Autoimmune diseases (AID) have familial aggregation and frequently share a common genetic predisposition. Only few small uncontrolled studies have evaluated the risk of AID…Abstract Number: 2126 • 2015 ACR/ARHP Annual Meeting
Trial of Atorvastatin for the Primary Prevention of Cardiovascular Events in Patients with Rheumatoid Arthritis
Background/Purpose: Patients with rheumatoid arthritis (RA) are at increased risk for cardiovascular disease (CVD) compared to the general population, both due to classical and novel…Abstract Number: 2127 • 2015 ACR/ARHP Annual Meeting
Exploring the Lipid Paradox Theory in Rheumatoid Arthritis: Subclinical Coronary Atherosclerosis Is Higher Among Rheumatoid Arthritis Patients with the Lowest Circulating Low Density Lipoprotein Concentrations Compared with Controls
Background/Purpose: Several recent studies have identified RA patients with very low levels of circulating total and low density lipoprotein cholesterol (LDL-C) to be at particularly…Abstract Number: 2128 • 2015 ACR/ARHP Annual Meeting
The Role of Insulin Resistance in the Development of Premature Atherosclerosis in Patients with Rheumatoid Arthritis
Background/Purpose: Accelerated atherosclerosis in rheumatoid arthritis (RA) is well established but the role of insulin resistance in RA pts without diabetes or metabolic syndrome remains…Abstract Number: 2129 • 2015 ACR/ARHP Annual Meeting
Treatment-Naïve, Early Rheumatoid Arthritis Patients Demonstrate Abnormalities of Vascular and Myocardial Function on Cardiac MRI
Treatment-na•ve, early rheumatoid arthritis patients demonstrate abnormalities of vascular and myocardial function on cardiac MRIB Erhayiem, A McDiarmid, PP Swoboda, A Kidambi, DP Ripley, TA…Abstract Number: 2130 • 2015 ACR/ARHP Annual Meeting
Primary Prevention of Myocardial Infarction in Rheumatoid Arthritis Using Low-Dose Aspirin: A Case-Crossover Study
Background/Purpose: Subjects with rheumatoid arthritis (RA) are at a higher risk of developing cardiovascular (CV) disease which is the leading cause of death in subjects…Abstract Number: 2131 • 2015 ACR/ARHP Annual Meeting
Younger Age and Female Gender Are the Main Determinants of Underestimation of Cardiovascular Risk in Rheumatoid Arthritis Patients
Background/Purpose: Rheumatoid arthritis (RA) patients have an increased cardiovascular (CV) risk. Current algorithms generally underestimate the risk in these patients [1]. In a meta-analysis, we…Abstract Number: 2132 • 2015 ACR/ARHP Annual Meeting
Monocarboxylate Transporter 4, Associated with the Acidification of Synovial Fluid, Is a Novel Therapeutic Target for Inflammatory Arthritis
Background/Purpose: Synovial fluid pH is decreased in patients with rheumatoid arthritis (RA)are unclear. Here, we examined the mechanism by which synovial fluid pH is regulated…Abstract Number: 2133 • 2015 ACR/ARHP Annual Meeting
Receptor Protein Tyrosine Phosphatase Alpha Enhances Rheumatoid Synovial Fibroblast Signaling and Promotes Arthritis in Mice
Background/Purpose: Rheumatoid arthritis (RA) fibroblast-like synoviocytes (FLS) promote disease pathogenesis by aggressively invading the joint extracellular matrix. The focal adhesion kinase (FAK) signaling pathway is…
ACR Meeting Abstracts