ACR Meeting Abstracts

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  • Abstract Number: 734 • 2014 ACR/ARHP Annual Meeting

    Lower Socioeconomic Status, Male Gender and Diffuse Scleroderma Are Associated with Worse Survival in the Pulmonary Hypertension Assessment and Recognition of Outcomes in Scleroderma Cohort

    Jessica K. Gordon1, Wei Zhang2, Lorinda Chung3, Yan Ma4, Virginia D. Steen5 and PHAROS Investigators, 1Rheumatology, Hospital for Special Surgery, New York, NY, 2Healthcare Research Institute, Hospital for Special Surgery, New York, NY, 3Immunology and Rheumatology, Stanford University School of Medicine, Palo Alto, CA, 4Research - Epidemiology and Biostatistics, Hospital for Special Surgery, New York, NY, 5Department of Rheumatology, Georgetown University Medical Center, Washington, DC

    Background/Purpose Lower socioeconomic status (SES) and male gender have been associated with worse survival in idiopathic pulmonary arterial hypertension (PAH).  Pulmonary Hypertension Assessment and Recognition…
  • Abstract Number: 733 • 2014 ACR/ARHP Annual Meeting

    Impact of Geographic Variation on the Risk of Digital Ulcers Development in Systemic Sclerosis: A Brazilian Multicenter Registry

    Eduardo José do Rosário e Souza1, Carolina de Souza Muller2, Andrea Tavares Dantas3, Henrique A. Mariz3, Alex Magno Coelho Horimoto4, Renato Alvarenga Rezende1, Isabela Guimarães2, Izaias Pereira da Costa4, Glauce Rejane Leonardi Bertazzi5, Luiza Paiola5, Eutília Andrade Medeiros Freire6, Roberta Ismael6, Ana Paula Toledo Del-Rio7, Juliana Sekiyama7, Carolina Barros Kahwage8 and Cristiane Kayser9, 1Serviço de Reumatologia, Hospital Santa Casa, Minas Gerais, Belo Horizonte, Brazil, 2Universidade Federal do Paraná, Curitiba, Brazil, 3Disciplina de Reumatologia, Hospital das Clínicas - Universidade Federal de Pernambuco, Recife, Brazil, 4Universidade Federal do Mato Grosso do Sul, Campo Grande, Brazil, 5Faculdade de Medicina de São José do Rio Preto, São José do Rio Preto, Brazil, 6Universidade Federal da Paraíba, João Pessoa, Brazil, 7Universidade Estadual de Campinas, Campinas, Brazil, 8Universidade Federal de São Paulo, São Paulo, Brazil, 9Rheumatology Division, Universidade Federal de São Paulo, São Paulo, Brazil

    Background/Purpose: Digital ulcers (DU) and Raynaud’s phenomenon (RP) are a frequent complication in patients with Systemic Sclerosis (SSc). The present study aimed to evaluate the…
  • Abstract Number: 732 • 2014 ACR/ARHP Annual Meeting

    Predictors of Inpatient Mortality in Patients with Systemic Sclerosis: A Case Control Study

    Shiv Tej Sehra1, Chris T. Derk1, Andrew Kelly2 and Joshua Baker3, 1Medicine/Rheumatology, University of Pennsylvania, Philadelphia, PA, 2Medicine, Pennsylvania Hospital, Philadelphia, PA, 3Medicine/Rheumatology, University of Pennsylvania and Philadelphia VAMC, Philadelphia, PA

    Background/Purpose There are few published studies on predictors of inpatient mortality in patients with systemic sclerosis (SSc). Knowledge of these predictors is important for early…
  • Abstract Number: 731 • 2014 ACR/ARHP Annual Meeting

    Performance of the Old ACR and the New ACR-EULAR Systemic Sclerosis Classification Criteria in Patients with Limited Cutaneous Disease: Effect on the Ascertainment of Severe Pulmonary Arterial Hypertension

    Beatriz E. Joven1, M Jesus Garcia de Yebenes2, Pilar Escribano3,4, Estibaliz Loza2,5, M Jose Ruiz-Cano4, Carmen Jimenez Lopez-Guarch4, Loreto Carmona6 and Patricia E. Carreira1, 1Rheumatology Department. Hospital Universitario 12 de Octubre, Madrid, Spain, 2Instituto de Salud Musculoesqueletica, Madrid, Spain, 3Multidisciplanry Pulmonary Hypertension Unit. Hospital Universitario 12 de Octubre, Madrid, Spain, 4Multidisciplinary Pulmonary Hypertension Unit. Hospital Universitario 12 de Octubre, Madrid, Spain, 5Institu, Madrid, Spain, 6Instituto de Salud Musculoesquelética, Madrid, Spain

    Background/Purpose To analyze the performance of the old ACR1980 and the new ACR-EULAR2013 classification criteria for systemic sclerosis (SSc) in patients with limited disease in…
  • Abstract Number: 730 • 2014 ACR/ARHP Annual Meeting

    Prediction of Cardiac and Vascular Events in Systemic Sclerosis: Input from Endothelin-1 Type a Receptor Antibodies

    Jerome Avouac1, Gabriela Riemekasten2, Christophe Meune3, Barbara Ruiz4 and Yannick Allanore1, 1Paris Descartes University, Rheumatology A Department and INSERM U1016, Cochin Hospital, Paris, France, 2Charité University Hospital and German Rheumatism Research Centre, a Leibniz Institute, Berlin, Germany, 3Paris 13 University, University Hospital of Paris-Seine-Saint-Denis, Cardiology Department, Bobigny, France, 4Paris Descartes University, INSERM U1016, Institut Cochin, Sorbonne Paris Cité, Paris, France

    Background/Purpose: Cardiac and peripheral microvascular alterations are key features of systemic sclerosis (SSc). We have previously reported that angiogenic markers can predict the cardiovascular outcomes…
  • Abstract Number: 729 • 2014 ACR/ARHP Annual Meeting

    A Dilated Esophagus Is an Independent Risk Factor for Interstitial Lung Disease in SSc

    Carrie Richardson1, Rishi Agrawal2, Jungwha Lee3, Orit Almagor4, John Varga5, Rowland W. Chang6 and Monique E. Hinchcliff7, 1Department of Medicine, McGaw Medical Center of Northwestern University, Chicago, IL, 2Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago, IL, 3Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 4Northwestern University, Chicago, IL, 5Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, 6Institute for Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 7Northwestern University, Feinberg School of Medicine, Chicago, IL

    Background/Purpose High-resolution computed tomography of the chest (HRCT) performed for assessment of interstitial lung disease (ILD) in patients with systemic sclerosis (SSc) frequently reveals a…
  • Abstract Number: 728 • 2014 ACR/ARHP Annual Meeting

    Prediction and Impact of Attacks of Raynaud’s Phenomenon, As Judged By Patient perception 

    Michael Hughes1, Amir Snapir2, Jack Wilkinson3, Daniel Snapir2, Fredrick M. Wigley4 and Ariane Herrick1, 1Centre for Musculoskeletal Research, The University of Manchester, Manchester, United Kingdom, 2Orion Corporation Orion Pharma, Turku, Finland, 3Research and Development, Salford Royal NHS Foundation Trust, Salford, United Kingdom, 4Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD

    Background/Purpose Our aim was to evaluate (a) whether subjects with Raynaud's phenomenon (RP) can predict RP attacks because if so, then this could have implications…
  • Abstract Number: 727 • 2014 ACR/ARHP Annual Meeting

    International Classification of Functioning, Disability, and Health (ICF) Core Sets for Connective Tissue Disease Interstitial Lung Disease (CTD-ILD) and Idiopathic Pulmonary Fibrosis (IPF) – a Necessary Map to Health Care Provision in the Era of ICD-11

    Reuben Escorpizo1,2, Kevin J. Keen3, Kim Fligelstone4, Matthew R. Lammi5, Daphne LeSage6, Anne-Marie Russell7, Surinder Birring8, Catherine Sarver9, Janos Varga10, Oliver Distler11 and Lesley Ann Saketkoo12, 1ICF Research Branch in cooperation with the WHO Collaborating Centre for the Family of International Classifications in Germany (DIMDI), Nottwil, Switzerland, 2Department of Physical Therapy, 2Louisiana State University Health Sciences Center, New Orleans, LA, 3University of Northern British Columbia, Health Research Institute, Prince George, BC, Canada, 4Royal Free Hospital, Scleroderma Unit and Scleroderma Society, London, United Kingdom, 5Louisiana State University Health Sciences Center, Pulmonary and Critical Medicine, New Orleans, LA, 6Center for CCH at State of Louisiana, New Orleans, LA, 7National Heart Lung Institute, Royal Brompton Hospital,, London, United Kingdom, 8King's College Hospital NHS Foundation Trust, London, United Kingdom, 9Johns Hopkins, Baltimore, MD, 10National Koranyi Institute for TB and Pulmonology, Budapest, Hungary, 11Division of Rheumatology, University Hospital Zurich, Zurich, Switzerland, 12Scleroderma and Sarcoidosis Patient Care and Research Center, Rheumatology and Pulmonary Medicine, Louisiana State University Health Sciences Center, New Orleans, LA

    Background/Purpose: A recent consensus project (Saketkoo et al, Thorax 2014) recommended a minimum core set of outcome measures for use in future clinical trials of…
  • Abstract Number: 726 • 2014 ACR/ARHP Annual Meeting

    Risk of Ischemic Stroke in Patients with Systemic Sclerosis: A Systematic Review and Meta-Analysis

    Patompong Ungprasert1, Praveen Ratanasrimetha2, Charat Thongprayoon3, Wisit Cheungpasitporn3 and Promporn Suksaranjit4, 1Department of Internal medicine, Bassett medical center, Cooperstown, NY, 2Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand, 3Department of Medicine, Mayo clinic, Rochester, MN, 4Department of Cardiology, University of Utah School of Medicine, Salt Lake City, UT

    Risk of Ischemic Stroke in Patients with Systemic Sclerosis: A Systematic Review and Meta-analysisBackground/Purpose: Several chronic inflammatory disorders, such as rheumatoid arthritis and systemic lupus…
  • Abstract Number: 725 • 2014 ACR/ARHP Annual Meeting

    Reduced Diffusing Capacity of Carbon Monoxide Is Independently Associated with Worse Subclinical Left Ventricular Function on Speckle-Tracking Echocardiography in Systemic Sclerosis

    Monique Hinchcliff1, Vistasp Daruwalla2, Lauren Beussink-Nelson3, Sofia Podlusky4, Mary A. Carns4, John Varga5, Michael Cuttica6 and Sanjiv J. Shah7, 1Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, 2Department of Internal Medicine, Division of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, IL, 3Department of Cardiology, Northwestern University Feinberg School of Medicine, Chicago, IL, 4Department of Medicine, Division of Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, 5Rheumatology, Northwestern University Feinberg School of Medicine, Chicago, IL, 6Department of Medicine, Division of Pulmonary and Critical Care Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 7Cardiology, Northwestern University Feinberg School of Medicine, Chicago, IL

    Background/Purpose: Reduced diffusing capacity of carbon monoxide (DLCO) is a predictor of worse outcomes in patients with systemic sclerosis (SSc). Traditionally, the association between low…
  • Abstract Number: 724 • 2014 ACR/ARHP Annual Meeting

    Moderate Decline in Forced Vital Capacity is Associated with a Poor Outcome in Systemic Sclerosis Patients

    Anna-Maria Hoffmann-Vold1, Oyvind Midtvedt2, Torhild Garen3, May Brit Lund4, T. Mogens Aalokken5, Jan Tore Gran2 and Oyvind Molberg6, 1Department of Rheumatology, Department of Rheumatology, Oslo University Hospital Rikshospitalet, Oslo, Norway, 2Rheumatology, Oslo University Hospital, Oslo, Norway, 3Department of Rheumatology, Oslo University Hospital Rikshospitalet, Oslo, Norway, 4Department of Respiratory Medicine, Oslo University Hospital Rikshopitalet, Oslo, Norway, 5Department of Radiology, Oslo University Hospital Rikshospitalet, Oslo, Norway, 6Department of Rheumatology, Oslo University Hospital, Rikshospitalet, Oslo, Norway

    Background/Purpose: Interstitial lung disease (ILD) is a common manifestation in systemic sclerosis (SSc) and the leading cause of morbidity and mortality. Serial pulmonary function tests…
  • Abstract Number: 723 • 2014 ACR/ARHP Annual Meeting

    Early Mortality in Australian, Canadian and Spanish Scleroderma Patients: Rationale for Establishing a Multi-National Inception Cohort of Patients with Systemic Sclerosis

    YanJie Hao1, Marie Hudson2,3, Patricia Carreira4, Wendy Stevens1,5, Candice Rabusa6, Solene Tatibouet7,8, Loreto Carmona9, Beatriz E Joven10, Susanna Proudman11,12, Murray Baron7,8 and Mandana Nikpour1,13, 1Rheumatology, St. Vincent’s Hospital Melbourne, Melbourne, Australia, 2Rheumatology, Lady David Institute for Medical Research and Jewish General Hospital, Montreal, QC, Canada, 3Division of Rheumatology, McGill University, Montreal, QC, Canada, 4Rheumatology, Hospital Universitario 12 de Octubre, Madrid, Spain, 5The University of Melbourne Department of Medicine at St. Vincent’s Hospital Melbourne, Melbourne, Australia, 6Rheumatology, The University of Melbourne at St Vincent’s Hospital, Melbourne, Australia, 7Rheumatology, Jewish General Hospital, Montreal, QC, Canada, 8Rheumatology, Lady David Research Institute, Montreal, QC, Canada, 9Instituto de Salud Musculoesqueletica, Madrid, Spain, 10Rheumatology, Hospital Universitario, Madrid, Spain, 11Rheumatology Unit, Royal Adelaide Hospital, Adelaide, Australia, 12Discipline of Medicine, University of Adelaide, Adelaide, Australia, 13Medicine, The University of Melbourne at St. Vincent’s Hospital, Melbourne, Australia

    Background/Purpose Studies of ‘prevalent' cohorts wherein most patients have longstanding disease at recruitment may underestimate mortality in systemic sclerosis (SSc) due to survivor bias. The…
  • Abstract Number: 722 • 2014 ACR/ARHP Annual Meeting

    Prediction of Improvement in Skin Fibrosis in Diffuse Cutaneous Systemic Sclerosis

    Rucsandra Dobrota1,2, Britta Maurer1, Nicole Graf3, Carina Mihai2, Otylia Kowal-Bielecka4, Yannick Allanore5 and Oliver Distler on behalf of the EUSTAR investigators and co-authors1, 1Division of Rheumatology, University Hospital Zurich, Zurich, Switzerland, 2Department of Internal Medicine and Rheumatology, Dr.I.Cantacuzino Hospital, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania, 3graf biostatistics, Winterthur, Switzerland, 4Department of Rheumatology and Internal Medicine, Medical University of Bialystok, Bialystok, Poland, 5Department of Rheumatology, University Paris Descartes and Cochin Hospital, Paris, France

    Background/Purpose Improvement of skin fibrosis over time is part of the “natural history” of patients with diffuse cutaneous systemic sclerosis (dcSSc). However, in the individual…
  • Abstract Number: 706 • 2014 ACR/ARHP Annual Meeting

    Humoral Immunodeficiency in Patients Presenting with Clinical Features of Systemic Lupus Erythematosus

    W. Winn Chatham1, Duncan Harmon2 and Harry W. Schroeder Jr.3, 1University of Alabama at Birmingham, Birmingham, AL, 2Medicine/Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 3Medicine, University of Alabama-Birmingham, Birmingham, AL

    Background/Purpose: Humoral immunodeficiency syndromes including common variable immune deficiency (CVID) are not uncommonly associated with autoimmunity. The spectrum of autoimmune disorders encountered in CVID patients…
  • Abstract Number: 705 • 2014 ACR/ARHP Annual Meeting

    Lupus Chest Pain in the Emergency Department:  a Common Diagnostic Dilemma

    Masoom Modi1, Mariko L. Ishimori1, Daniel J. Wallace2 and Michael Weisman1, 1Rheumatology, Cedars-Sinai Medical Center, Los Angeles, CA, 2Rheumatology, Cedars-Sinai/David Geffen School of Medicine at UCLA, Los Angeles, CA

    Background/Purpose:   Chest pain (CP) is a common symptom reported by SLE patients often leading to presentation to Emergency Departments (ED). The origin of CP…
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