Abstract Number: 791 • 2014 ACR/ARHP Annual Meeting
Comparison of Clinical Manifestations in Different Histological Subsets of Biopsy-Proven Giant Cell Arteritis
Background/Purpose: Temporal artery biopsy (TAB) showing transmural inflammation is considered the gold standard for the diagnosis of giant cell arteritis (GCA). In some cases of…Abstract Number: 790 • 2014 ACR/ARHP Annual Meeting
Correlations Between Histopathological Findings and Clinical Manifestations in a Large Monocentric Cohort of Patients with Biopsy-Proven Giant Cell Arteritis
Background/Purpose: Giant cell arteritis (GCA) is a vasculitis that involves large and medium sized arteries in patients older than 50 years. Temporal artery biopsy (TAB)…Abstract Number: 789 • 2014 ACR/ARHP Annual Meeting
Association Between Histological Features and Clinical Features of Patients with Biopsy Positive Giant Cell Arteritis
Background/Purpose: Temporal artery biopsy is the gold standard for diagnosing giant cell arteritis (GCA). The pathology of GCA characteristically involves transmural infiltrates, giant cell formation…Abstract Number: 788 • 2014 ACR/ARHP Annual Meeting
Fast-Track Diagnostic Procedure for Giant Cell Arteritis
Background/Purpose Giant cell arteritis (GCA) represents the most common primary vasculitis among adults aged 50 years or above. Recently, the national annual incidence rate in…Abstract Number: 787 • 2014 ACR/ARHP Annual Meeting
Cardiovascular Risk Factors and Incident Giant Cell Arteritis
Background/Purpose: To assess the effect of cardiovascular risk factors on incidence GCA within a longitudinal cohort study in which detailed information on cardiovascular risk factors…Abstract Number: 786 • 2014 ACR/ARHP Annual Meeting
The Incidence and Mortality Rates of Giant Cell Arteritis in Southern Norway Are Lower Than Previous Reported
The Incidence and Mortality rates of Giant Cell Arteritis in Southern Norway are lower than Previous ReportedBackground/Purpose Giant cell arteritis (GCA) is the most common…Abstract Number: 785 • 2014 ACR/ARHP Annual Meeting
Incidence, Prevalence and Survival of Biopsy-Proven Giant Cell Arteritis in Northern Italy
Background/Purpose: To investigate the incidence, prevalence and mortality of biopsy proven giant cell arteritis (GCA) over a 27-year period in a defined area of northern…Abstract Number: 784 • 2014 ACR/ARHP Annual Meeting
Novel Inhibitory Effects of Mast Cells in Aortitis Involves Aortic Expression of Suppressor of Cytokine Signaling-1
Background/Purpose Early in the pathogenesis of Giant Cell Arteritis (GCA) dendritic cells interact with T cells of both Th1 and Th17 origin. IL-6; released by…Abstract Number: 783 • 2014 ACR/ARHP Annual Meeting
Increased Migration and Proliferation Potential Characterize Vascular Smooth Muscle Cells from Patients with Giant Cell Arteritis
Background/Purpose The pathophysiology of GCA is poorly understood. Questions remain regarding the mechanisms underlying vascular remodeling. Methods Vascular smooth muscle cells (VSMC) were cultured from…Abstract Number: 782 • 2014 ACR/ARHP Annual Meeting
Temporal Artery Microbiome in Giant Cell Arteritis
Background/Purpose: Whether infectious agents play a part in giant cell arteritis (GCA) remains controversial. We have performed the first microbiome study of snap-frozen temporal arteries,…Abstract Number: 780 • 2014 ACR/ARHP Annual Meeting
Novel Roles for Zyxin in the Pathogenesis of Giant Cell Arteritis
Background/Purpose �:The mechanisms of the blood vessel injury in giant cell arteritis (GCA), a systemic vasculitis characterized by inflammation of large- and medium-sized vessels, remain…Abstract Number: 781 • 2014 ACR/ARHP Annual Meeting
Rho Kinase (ROCK) Activity in Aortitis: Comparison of Giant Cell Arteritis (GCA), Takayasu Arteritis (TA) and Isolated Aortitis (IA)
Background/Purpose Aberrant ROCK activity is implicated in the pathogenesis of many autoimmune and vascular disease states as ROCKs promote Th17 differentiation and vascular remodeling. Increased…Abstract Number: 799 • 2014 ACR/ARHP Annual Meeting
Peripheral Arterial Disease in Patients with Giant Cell Arteritis: A Systematic Review and Meta-Analysis
Peripheral Arterial Disease in Patients with Giant Cell Arteritis: A Systematic Review and Meta-analysisBackground/Purpose: Several chronic inflammatory disorders, such as rheumatoid arthritis and systemic lupus…Abstract Number: 776 • 2014 ACR/ARHP Annual Meeting
A Candidate Gene Approach Identifies IL33 as a Novel Genetic Risk Factor for GCA
Background/Purpose: IL-33, through binding to its receptor ST2 (suppression of tumorigenicity 2), encoded by the interleukin 1 receptor-like 1 (IL1RL1) gene, activates mast cells and…Abstract Number: 775 • 2014 ACR/ARHP Annual Meeting
HLA-DRB1 Alleles in Susceptibility to Giant Cell Arteritis: Literature Review and Meta-Analysis
Background/Purpose Giant cell arteritis (GCA) has been reported by many studies (but not all) to be associated with carriage of HLA-DRB1*04, with variable results relating to…
ACR Meeting Abstracts