Abstract Number: 1195 • 2014 ACR/ARHP Annual Meeting
Activation of the nlrp3 Inflammasome By an Endogenous TLR2 Ligand in Rheumatoid Arthritis
Background/Purpose: The inflammasome is a large multiprotein complex which plays a key role in innate immunity by mediating the production of pro-inflammatory cytokines interleukin-1β (IL-1β)…Abstract Number: 1194 • 2014 ACR/ARHP Annual Meeting
Cofilin-1 Is a ROS Sensor in Regulating the NLRP3 Inflammasome
Background/Purpose NLRP3 (NOD-like receptor family, pyrin domain containing 3) has a pivotal role in nucleating inflammasome, cytoplasmic multiprotein complexes that mediate the maturation of the…Abstract Number: 1193 • 2014 ACR/ARHP Annual Meeting
Diagnostic value of Contrast-Enhanced MR-Angiography in diagnosing large Vessel Vasculitis
Background/Purpose Diagnosis of large-vessel vasculitis (LVV) remains difficult despite clinical and serological signs and symptoms. Detection by histology might be unavailable in exclusive thoracic or…Abstract Number: 1192 • 2014 ACR/ARHP Annual Meeting
Erosions Detected By Magnet Resonance Imaging in Patients with Juvenile Idiopathic Arthritis (JIA) Are True Erosions As Visualized By Computed Tomography
Background/Purpose Chronic arthritis occurs relatively frequent in childhood. Patients with polyarticular disease might have a destructive disease course and thus a worse outcome. In adult…Abstract Number: 1191 • 2014 ACR/ARHP Annual Meeting
The Kimriss Bone Marrow Lesion Score in Patients with Osteoarthritis of the Knee Correlates with WOMAC Pain Status Using Target-Lesion Based Scoring Methodology; Data from the Osteoarthritis Initiative
Background/Purpose: Inflammatory components of osteoarthritis including bone marrow lesions (BML) may be a target for therapy. Limited literature quantifies the relation of these markers on…Abstract Number: 1190 • 2014 ACR/ARHP Annual Meeting
Osteoarthritis-like Changes Are Present in the Tibia and Femur 1 Year Following ACL Reconstruction
Background/Purpose Statistical Shape Modeling (SSM) is a promising tool that has the ability to characterize complex shapes in a brief feature vector. The application of…Abstract Number: 1189 • 2014 ACR/ARHP Annual Meeting
Conventional Magnetic Resonance Imaging (MR) and Hybrid 18F-Fluoride Positron Emission Tomography MRI (18F-F- PET/MRI) of the Spine and the Sacroiliac Joints – a Detailed Description of Pathologic Signals in Patients with Active Ankylosing Spondylitis
Background/Purpose: PET is a nuclear imaging technique that depicts functional processes within the body based on gamma rays. The biologically active molecule used for PET…Abstract Number: 1188 • 2014 ACR/ARHP Annual Meeting
Reproducibility of Magnetic Resonance Imaging Diffusion Weighted Imaging in Axial Spondyloarthritis Patients and Healthy Subjects
Reproducibility of Magnetic Resonance Diffusion Weighted Imaging In Axial Spondyloarthritis Patients and Healthy Subjects.Background/Purpose: Diffusion weighted imaging (DWI) is a magnetic resonance imaging (MRI) technique…Abstract Number: 1187 • 2014 ACR/ARHP Annual Meeting
Scoring of Spinal Lesions Compatible with Axial Spondyloarthritis on MRI in Clinical Practice By Local Radiologist or Rheumatologist in Desir; Comparison with Central Reading
Background/Purpose: In clinical practice radiologists and rheumatologists assess whether lesions compatible with axial SpondyloArthritis (axSpA) are present on spinal MRI. The objective was to compare…Abstract Number: 1186 • 2014 ACR/ARHP Annual Meeting
Prevalence of MRI Spinal Lesions Typical for Axial Spondyloarthritis in Patients with Inflammatory Back Pain
Background/Purpose: A cut-off value of ³3 inflammatory lesions was suggested by the ASAS/OMERACT group, as positive MRI of the spine (MRI-spine). Moreover, fatty lesions on…Abstract Number: 1185 • 2014 ACR/ARHP Annual Meeting
Feature of Fatty Deposition in Sacroiliac Joints in Ankylosing Spondylitis Patients Seen By MRI
Background/Purpose: Fatty deposition (FD) is often seen in ankylosing spondylitis (AS) patients in the sacroiliac joints (SIJs). Magnetic Resonance Imaging (MRI) is a useful equipment…Abstract Number: 1184 • 2014 ACR/ARHP Annual Meeting
Subclinical Inflammation in Psoriatic Patients with No History of Psoriatic Arthritis: An Assessment By Magnetic Resonance Imaging
Background/Purpose Six to 39% of patients with cutaneous psoriasis (PSO) can develop psoriatic arthritis (PsA). The transition from skin disease to joint involvement is only…Abstract Number: 1182 • 2014 ACR/ARHP Annual Meeting
Do Patients with Active RA Also Have Inflamed Atherosclerotic Plaques on PET-MRI?
Background/Purpose: Inflammation plays a key role in the progression and destabilisation of atherosclerotic plaque in the general population. In RA, inflammation is thought to accelerate…Abstract Number: 1181 • 2014 ACR/ARHP Annual Meeting
Effects of Tofacitinib on Bone Marrow Edema, Synovitis, and Erosive Damage in Methotrexate-Naïve Patients with Early Active Rheumatoid Arthritis (Duration ≤2 Years): Results of an Exploratory Phase 2 MRI Study
Background/Purpose: Inflammation of the synovium and in particular the bone marrow, as assessed by magnetic resonance imaging (MRI), have been identified as prognostic indicators of…Abstract Number: 1200 • 2014 ACR/ARHP Annual Meeting
Plasma Levels of Pattern Recognition Molecules of the Lectin Pathway Are Altered in SLE Patients
Background/Purpose Systemic Lupus Erythematosus (SLE) is a complex autoimmune disease where the Complement System plays a key role in the pathogenesis. The objective of this…
ACR Meeting Abstracts