Abstract Number: 1351 • 2015 ACR/ARHP Annual Meeting
Long-Term Efficacy of Latent Tuberculosis Infection Screening in Juvenile Idiopathic Arthritis Patients Prior to Anti-TNF Treatment in an Endemic Area
Background/Purpose: We have demonstrated previously that latent tuberculosis infection (LTBI) screening is effective in adult rheumatoid arthritis (RA) patients prior to anti-TNF treatment. One study…Abstract Number: 1352 • 2015 ACR/ARHP Annual Meeting
How Frequently Does Tuberculosis Screening Test Become Positive in Rheumatic Patients Treated with ANTI-Tumor Necrosis Factor-ALPHA Therapy? an Analysis of Risk Factors
Background/Purpose: Anti-tumor necrosis factor-α (TNF-α) therapy is associated with an increased risk of mycobacterium tuberculosis infection. Tuberculosis (TB) reactivation can lead to severe complications in…Abstract Number: 1354 • 2015 ACR/ARHP Annual Meeting
Whipple’s Disease: The Diagnostic Utility of Synovial Fluid Tropheryma Whipplei Polymerase Chain Reaction
Background/Purpose: Inflammatory arthritis is a common, non-specific symptom of Whipple’s disease. Recovery of the organism by conventional culture is often unsuccessful. Synovial fluid polymerase chain…Abstract Number: 1355 • 2015 ACR/ARHP Annual Meeting
Ankle Periarthritis, a New Sign for Chikungunya : Ultrasound Study of Joint Lesions at the Acute Phase of Chikungunya
Background/Purpose: Chikungunya (CHIK) is a viral disease transmitted by the Aedes mosquito. The acute phase of the disease combines: fever, fatigue, arthralgia, arthritis, rash .…Abstract Number: 1356 • 2015 ACR/ARHP Annual Meeting
Autoimmune Manifestations in Hepatitis C: A Single-Centered Experience
Background/Purpose: Hepatitis C infection (HCV) is a leading cause of chronic liver disease. It is associated with a plethora of autoimmune manifestations including clinical, serological…Abstract Number: 1357 • 2015 ACR/ARHP Annual Meeting
Cytomegalovirus (CMV) Infections in Patients with Rheumatic Diseases: Experience of a Referral Center
Background/Purpose: CMV is a ubiquitous herpes virus associated with significant immunosuppression. Immunosuppressive treatments and ageing is well known risk factors for CMV reactivation. There are…Abstract Number: 1358 • 2015 ACR/ARHP Annual Meeting
Detection of a Unique Viral Infection in Salivary Glands of Sjögren’s Syndrome Patients and Viral-Mediated Recapitulation of Disease in Vivo
Background/Purpose: A viral infection is thought to be one of the triggers in the development of primary Sjögren’s syndrome (pSS). Multiple studies have shown stimulation…Abstract Number: 1359 • 2015 ACR/ARHP Annual Meeting
Risk Factors for the Development of Gout in HIV Patients: A Retrospective Study
Background/Purpose: The interaction between human immunodeficiency virus (HIV) disease and rheumatic disorders has been described as “an unfortunate experiment of nature” that could provide insights…Abstract Number: 1360 • 2015 ACR/ARHP Annual Meeting
Functional Consequences of NOD2 Gene Variants in Patients with NOD2-Associated Autoinflammatory Disease
Background/Purpose: Yao Syndrome (YS) is a systemic autoinflammatory disease formerly termed Nucleotide-binding oligomerization domain 2 (NOD2)-associated AutoInflammatory Disease (NAID) due to its association with specific…Abstract Number: 1361 • 2015 ACR/ARHP Annual Meeting
Synovial Macrophages Promote TGF-β Signaling but Protect Against Influx of S100A8/S100A9-Producing Cells after Intra-Articular Injections of Oxidized Low-Density Lipoproteins
Background/Purpose: In previous studies we found that synovial macrophages regulate joint pathology during experimental osteoarthritis (OA). Recently, we found that high systemic levels of LDL…Abstract Number: 1362 • 2015 ACR/ARHP Annual Meeting
Investigating the Role of Dendritic Cell Maturation & T Cell Activation within the Inflamed Synovium in Rheumatoid Arthritis
Background/Purpose: Dendritic cells (DC) are a heterogeneous population of antigen presenting cells which link both innate & adaptive immunity. To date their classification within blood…Abstract Number: 1363 • 2015 ACR/ARHP Annual Meeting
Changes in Cyclooxygenase-2’s Expression, and PGE2’s and 6-Keto-PGF1α Levels in the Presence of the Muscarinic Acethylcholine Receptor Antibody in Primary Sjogren Syndrome
Background/Purpose: to assess the inflammatory process provoked by the M3 muscarinic acetylcholine receptor antibody from primary Sjogren Syndrome (pSS) patient’s sera in rat submandibular gland…Abstract Number: 1364 • 2015 ACR/ARHP Annual Meeting
Treating Experimental Arthritis with the Innate Immune Inhibitor IL-37 Reduces Joint and Systemic Inflammation
Background/Purpose: Characterized as a fundamental inhibitor of innate inflammation, IL‑1 family member IL‑37 is expressed in the synovia of patients with rheumatoid arthritis. We investigated…Abstract Number: 1365 • 2015 ACR/ARHP Annual Meeting
Innate Lymphoid Cells. New Players in Systemic Sclerosis Correlate with Extent of Skin and Lung Fibrosis
Background/Purpose: Type 2 innate lymphoid cells (ILC2s), are recently identified as population of cells with lymphoid morphology lacking re-arranged antigen-specific receptors. Although findings in animal…Abstract Number: 1366 • 2015 ACR/ARHP Annual Meeting
Natural Antibodies, Not B Cells, Contribute to Acute Cell Death-Induced Inflammation
Background/Purpose: Alarmins, such as uric acid, released from dying cells activate inflammasomes and mediate dead cell-induced inflammation (Ref.). Since it is remains unknown whether or…
ACR Meeting Abstracts