Abstracts Archive - Page 1958 of 2607 - ACR Meeting Abstracts

Abstract Number: 1305 • 2015 ACR/ARHP Annual Meeting
Prevalence of MR-Detected Ramris-Defined Erosions in the General Population
L. Mangnus¹, H.W. van Steenbergen², M. Reijnierse³ and A.H.M. van der Helm- van Mil¹, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Leiden University Medical Center, Leiden, Netherlands, ³Radiology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: The diagnostic value of Magnetic Resonance (MR) imaging for Rheumatoid Arthritis (RA) is undetermined. The main value of MR is its sensitive depiction of…
Abstract Number: 1306 • 2015 ACR/ARHP Annual Meeting
MRI Erosions in Undifferentiated Arthritis. Different Associations with the Collagen IIA N-Terminal Propeptide (PIIANP) and Galectin-3 in Pre-RA and Other Arthritides
Saida Farah Issa¹, Anne Duer², Mikkel Østergaard³, Hanne Lindegaard¹, Kim Hørslev-Petersen⁴, Merete Lund Hetland⁵, Jakob M. Møller⁶, Anne Friesgaard Christensen⁷ and Peter Junker¹, ¹Department of Rheumatology, Odense University Hospital, Odense, Denmark, ²Department of Rheumatology, Copenhagen University Hospital at Hvidovre, Hvidovre, Denmark, ³Center for Rheumatology and Spine Diseases, Glostrup Hospital, Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Rigshospitalet - Glostrup, University of Copenhagen, Denmark, Glostrup, Denmark, ⁴Rheumatology, Research Unit at King Christian X Hospital for Rheumatic Diseases, Graasten, Denmark, ⁵DANBIO, Center for Rheumatology and Spine Diseases, Glostrup Univ Hospital, Glostrup, Denmark, ⁶Department of Radiology, Copenhagen University Hospital Herlev, Herlev, Denmark, ⁷Department of Rheumatology, Vejle Hospital, Vejle, Denmark
Background/Purpose: Galectin-3 has been implicated as a mediator of inflammation and erosive progression in animal arthritis and rheumatoid arthritis(RA). The type IIA procollagen peptide(PIIANP) is…
Abstract Number: 1307 • 2015 ACR/ARHP Annual Meeting
Does Computerized Segmentation of Early Erosions on Magnetic Resonance Imaging Predict Functional Ability in Rheumatoid Arthritis?
Matthew Jessome¹, Michael Tomizza¹, Karen A. Beattie², William G. Bensen², Raja Bobba², Alfred Cividino², Patrick D. Emond², Chris Gordon², Lawrence Hart², George Ioannidis², Maggie Larche², Arthur Lau³, Ruben Tavares², Stephen Tytus² and Jonathan D. Adachi², ¹McMaster University, Hamilton, ON, Canada, ²St Joseph's Healthcare Hamilton, Hamilton, ON, Canada, ³Division of Rheumatology, McMaster University, Hamilton, ON, Canada
Background/Purpose: Functional ability of rheumatoid arthritis (RA) patients is reduced by both acute (inflammatory) and chronic (joint damage) disease manifestations. However, the impact of early…
Abstract Number: 1308 • 2015 ACR/ARHP Annual Meeting
MRI Measures of Disease Activity and Joint Damage Are Associated with Patient-Reported Outcomes in Rheumatoid Arthritis
Joshua Baker¹, Philip G. Conaghan², Daniel Baker³, Paul Emery⁴ and Mikkel Østergaard⁵, ¹Medicine/Rheumatology, University of Pennsylvania, Philadelphia, PA, ²University of Leeds & NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds, United Kingdom, ³Immunology, Centocor Inc., Malvern, PA, ⁴Division of Rheumatic and Musculoskeletal Disease, University of Leeds, Leeds, United Kingdom, ⁵Center for Rheumatology and Spine Diseases, Glostrup Hospital, Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Rigshospitalet - Glostrup, University of Copenhagen, Denmark, Glostrup, Denmark
Background/Purpose: We used data from a large clinical trial of golimumab (GO-BEFORE) to comprehensively assess associations between magnetic resonance imaging (MRI) measures of synovitis, osteitis,…
Abstract Number: 1309 • 2015 ACR/ARHP Annual Meeting
Defining an Acceptable Level of MRI Inflammation in Rheumatoid Arthritis
Joshua Baker¹, Mikkel Østergaard², Daniel Baker³, Paul Emery⁴ and Philip G. Conaghan⁵, ¹Medicine/Rheumatology, University of Pennsylvania, Philadelphia, PA, ²Center for Rheumatology and Spine Diseases, Glostrup Hospital, Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Rigshospitalet - Glostrup, University of Copenhagen, Denmark, Glostrup, Denmark, ³Immunology, Centocor Inc., Malvern, PA, ⁴Division of Rheumatic and Musculoskeletal Disease, University of Leeds, Leeds, United Kingdom, ⁵University of Leeds & NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds, United Kingdom
Background/Purpose: Imaging-detected inflammation persists in many rheumatoid arthritis (RA) patients despite therapy. We used data from two clinical trials of golimumab to determine thresholds for…
Abstract Number: 1310 • 2015 ACR/ARHP Annual Meeting
Efficacy of Abatacept in Patients with Rheumatoid Arthritis Assessed By MRI Scans of Bilateral Hands
Yuji Kukida¹, Akiko Kasahara¹, Takahiro Seno^1,2, Yu Isoda¹, Tomoya Sagawa¹, Takuya Inoue¹, Naoka Kamio¹, Risa Sagawa¹, Takashi Kida¹, Amane Nakabayashi¹, Hidetake Nagahara³, Ken Murakami¹, Aihiro Yamamoto¹, Satoshi Morita⁴, Hirotoshi Ito⁵, Masataka Kohno¹ and Yutaka Kawahito¹, ¹Inflammation and Immunology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan, ²Department of Rheumatic Diseases and Joint Function, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan, ³Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan, ⁴Department of Biomedical Statistics and Bioinformatics, Kyoto University Graduate School of Medicine, Kyoto, Japan, ⁵Department of Radiology, Kajiicho Medical Imaging Center, Kyoto, Japan
Background/Purpose: Previous radiographic and MRI studies have demonstrated that abatacept (ABT) can inhibit the progression of bone and joint destruction in patients with rheumatoid arthritis…
Abstract Number: 1311 • 2015 ACR/ARHP Annual Meeting
Effect of a Non Biologic Treat-to-Target Strategy on MRI-Determined Inflammatory and Destructive Changes in Early Rheumatoid Arthritis – Results from a 2-Year Investigator-Initiated Double-Blind Randomized Controlled Clinical Trial
Signe Moller-Bisgaard^1,2, Bo Jannik Ejbjerg², Iris Eshed³, Kim Horslev-Petersen⁴, Merete Lund Hetland⁵, Anne G. Jurik⁶, Jørgen Vallø⁷, Henrik Thomsen⁸, Trine Torfing⁹, Kristian Stengaard-Pedersen¹⁰, Peter Junker¹¹, Niels Steen Krogh¹², Tine Lottenburger¹³, Torkell Ellingsen¹⁴, Lis Smedegaard Andersen¹⁵, Ib Hansen¹⁰, Henrik Skjødt¹⁶, Anders Svendsen¹⁴, Ulrik Tarp¹⁰, Jan Pødenphant¹⁵, Jens Kristian Pedersen⁷, Hanne Lindegaard¹⁴ and Mikkel Østergaard¹, ¹Center for Rheumatology and Spine Diseases, Glostrup Hospital, Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Rigshospitalet - Glostrup, University of Copenhagen, Denmark, Glostrup, Denmark, ²Department of Rheumatology, Slagelse University Hospital, Slagelse, Denmark, ³Department of Radiology, Sheba Medical Center, Tel Hashomer, Israel, ⁴Reumatologi, Kong Christian X's Gigthospital, Grasten, Denmark, ⁵DANBIO, Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Glostrup, Denmark, ⁶Department of Radiology, Aarhus University Hospital, Aarhus, Denmark, ⁷University Hospital at Southern Denmark, Odense, Denmark, ⁸Department of Radiology, Copenhagen University Hospital Herlev, Copenhagen, Denmark, ⁹Department of Radiology, University Hospital at Southern Denmark, Odense, Denmark, ¹⁰Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark, ¹¹University of Southern Denmark, Odense, Denmark, ¹²ZiteLab ApS, Copenhagen, Denmark, ¹³Department of Rheumatology, University Hospital at Southern Denmark, Vejle, Denmark, ¹⁴Department of Rheumatology, Odense University Hospital, Odense, Denmark, ¹⁵Department of Rheumatology, Copenhagen University Hospital, Gentofte, Denmark, ¹⁶Center for Rheumatology and Spine Diseases, Glostrup Hopital, Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Rigshospitalet - Glostrup, University of Copenhagen, Denmark, Glostrup, Denmark
Background/Purpose: MRI has proved to be more sensitive than clinical examination and x-ray for detection of inflammatory and destructive joint changes in early rheumatoid arthritis…
Abstract Number: 1312 • 2015 ACR/ARHP Annual Meeting
Radiocarpal Cartilage Matrix Changes 3-Months after Anti-TNF Treatment for Rheumatoid Arthritis – Feasibility Study Using MR T1ρ� Imaging
Eric Ku¹, Valentina Pedoia², Matthew Tanaka³, Ursula Heilmeier¹, John Imboden⁴, Jonathan D. Graf⁵, Thomas M. Link⁶ and Xiaojuan Li⁷, ¹Department of Radiology & Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, UCSF, San Francisco, CA, ²Department of Radiology & Biomedical Imaging, Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, ³University of California Berkeley, Berkeley, CA, ⁴Rheumatology, Rheumatology, University of California San Francisco, San Francisco, CA, ⁵Rosalind Russell / Ephraim P. Engleman Rheumatology Research Center, University of California, San Francisco, San Francisco, CA, ⁶Department of Radiology and Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, UCSF, San Francisco, CA, ⁷Radiology & Biomedical Imaging, Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA
Background/Purpose: Standard assessment of Rheumatoid Arthritis (RA) on MRI relies on semi-quantitative joint space narrowing scores that are not sensitive to cartilage focal lesions or…
Abstract Number: 1313 • 2015 ACR/ARHP Annual Meeting
Tumour Necrosis Factor Inhibitor Treatment Normalises Hand Bone Loss in a Minority of Rheumatoid Arthritis Patients Treated in Clinical Practice. Results from the Copenhagen Osteoarthritis Study and the Danbio Registry
Lykke Midtbøll Ørnbjerg¹, Mikkel Østergaard¹, Trine David Jensen², Pernille Bach Mortensen², Lars Hyldstrup², Pernille Boyesen³, Anja Thormann¹, Ulrik Tarp¹, Wolfgang Bøhme¹, Hanne Lindegaard¹, Uta Engling Poulsen¹, Annette Hansen¹, Annette Schlemmer¹, Niels Graudal¹, Anne Rødgaard Andersen¹, Jakob Espesen¹, Gina Kollerup¹, Bente Glintborg¹, Ole Rintek Madsen¹, Dorte Vendelbo Jensen¹ and Merete Lund Hetland¹, ¹DANBIO, On behalf of Depts of Rheumatology, North, South, Central, Zealand and Capital Region, Copenhagen, Denmark, ²Dept. of Endocrinology, Hvidovre Hospital, Copenhagen, Denmark, ³Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway
Background/Purpose: Rheumatoid arthritis (RA) is characterised by progressive joint destruction and loss of periarticular bone mass. Thus hand bone loss (HBL) has been proposed as…
Abstract Number: 1314 • 2015 ACR/ARHP Annual Meeting
Quantitative MRI Measurement of Tenosynovitis Demonstrates Differing Responses of Synovitis and Tenosynovitis after RA Treatment
Michael A. Bowes¹, Gwenael Guillard¹, Graham R. Vincent², Jane E. Freeston³, Edward M. Vital⁴, Paul Emery⁵ and Philip G. Conaghan⁶, ¹Imorphics, Manchester, United Kingdom, ²Imorphics Ltd, Manchester, United Kingdom, ³LIMM Section of Musculoskeletal Disease, University of Leeds, Leeds, United Kingdom, ⁴Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, ⁵Leeds Institute of Rheumatic and Musculoskeletal Medicine, Leeds Gen Infirmary, Leeds, United Kingdom, ⁶University of Leeds & NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds, United Kingdom
Background/Purpose: Inflammation of the tendon sheaths (tenosynovitis) is a recognised component of rheumatoid arthritis (RA). A comprehensive assessment of inflammation will require the inclusion of…
Abstract Number: 1315 • 2015 ACR/ARHP Annual Meeting
Detecting Subtle Changes in Bone Structure Following Three-Month Anti-TNF Theraphy Using High-Resolution Peripheral Quantitative Computed Tomography
Matthew Tanaka¹, Favian Su², Min Hee Lee^3,4, Andrew J. Burghardt⁵, Thomas M. Link⁴, Jonathan D. Graf⁶, John Imboden⁷ and Xiaojuan Li⁸, ¹University of California Berkeley, Berkeley, CA, ²Radiology and Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, UCSF, San Francisco, CA, ³Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 138-736, South Korea, ⁴Department of Radiology and Biomedical Imaging, Musculoskeletal Quantitative Imaging Research, UCSF, San Francisco, CA, ⁵Department of Radiology & Biomedical Imaging, Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, ⁶Rosalind Russell / Ephraim P. Engleman Rheumatology Research Center, University of California, San Francisco, San Francisco, CA, ⁷Rheumatology, Rheumatology, University of California San Francisco, San Francisco, CA, ⁸Radiology & Biomedical Imaging, Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA
Background/Purpose: Radiographs have been traditionally used to detect bone erosions and joint space narrowing (JSN) in rheumatoid arthritis (RA), but they are not sensitive to…
Abstract Number: 1316 • 2015 ACR/ARHP Annual Meeting
Is MRI of Use in Identifying Which Undifferentiated Arthritis Patients Will Develop RA?
W.P. Nieuwenhuis¹, E.C. Newsum¹, H.W. van Steenbergen², L. Mangnus¹, T. W. J. Huizinga¹, M. Reijnierse³ and A.H.M. van der Helm- van Mil², ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Leiden University Medical Center, Leiden, Netherlands, ³Radiology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: The 2010 ACR/EULAR criteria for rheumatoid arthritis (RA) identify RA patients earlier than the 1987 ACR criteria. However, still a considerable amount of patients…
Abstract Number: 1317 • 2015 ACR/ARHP Annual Meeting
Clinical Utility of Joint Space Width and X-Ray Radiogrammetry in RA: Markers for Early Radiographic Progression
Michael Platten¹, Yogan Kisten², Johan Kälvesten³, Kristina Forslind⁴ and Ronald F. van Vollenhoven⁵, ¹Medicine, Karolinska Institutet, Huddinge, Sweden, ²ClinTRID, Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), The Karolinska Institute, Stockholm, Sweden, ³Sectra AB, Stockholm, Sweden, ⁴Department of Medicine, Helsingborgs Lasarett, Section of Rheumatology, Helsingborg, Sweden, ⁵Department of Medicine, Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), The Karolinska Institute, Stockholm, Sweden
Background/Purpose: Early prediction of radiographic progression is beneficial in rheumatoid arthritis (RA) patient management. The van der Heijde modified Sharp score (SHS) is currently the…
Abstract Number: 1318 • 2015 ACR/ARHP Annual Meeting
Prediction of Large Joint Destruction in Patients with Rheumatoid Arthritis Using FDG-PET/CT: A Prospective Study
Takahito Suto, Koichi Okamura, Yukio Yonemoto, Chisa Okura and Kenji Takagishi, Department of Orthopaedic Surgery, Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan
Background/Purpose: The assessments of joint damage in patients with rheumatoid arthritis (RA) are mainly restricted to small joints in the hands and feet. However, the…
Abstract Number: 1319 • 2015 ACR/ARHP Annual Meeting
18F-Fluorodeoxyglucose Positron Emission Computer Tomography and Ultrasonography for Assessing Remission in Patients with Rheumatoid Arthritis
Charline Rinkin¹, Pacôme Fosse², Nathalie Chapelier¹, Laurence Seidel³, Adelin Albert³, Roland Hustinx⁴ and Michel Malaise¹, ¹Rheumatology Department, CHU of Liège, Liège, Belgium, ²Nuclear Medicine Department, CHU of Angers, Angers, France, ³Biostatistic Department, CHU of Liège, Liège, Belgium, ⁴Nuclear Medicine Department, CHU of Liège, Liège, Belgium
Background/Purpose: The disease activity score based on 28 joints (DAS-28) might not be sufficient to assess remission in rheumatoid arthritis (RA). Several studies have shown…

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