Abstract Number: 1699 • 2014 ACR/ARHP Annual Meeting
Endothelial and Platelet Microparticles As Potential Novel Biomarkers of Peripheral Microvascular Dysfunction in Systemic Sclerosis and Primary Raynaud’s Phenomenon
Background/Purpose Microparticles (MPs) are membrane-bound vesicles derived from vascular and intravascular cells such as endothelial cells (EMPs) and platelets (PMPs). MPs form during cell activation…Abstract Number: 1700 • 2014 ACR/ARHP Annual Meeting
Laser Speckle Contrast Analysis in the Follow-up of Digital Ulcers in Systemic Sclerosis Patients
Background/Purpose . Typical clinical aspects of systemic sclerosis (SSc) include microvascular damage and reduction of peripheral blood perfusion, resulting in increased incidence of digital ulcers…Abstract Number: 1701 • 2014 ACR/ARHP Annual Meeting
Short-Term Effects of Iloprost on Micro-Vessels Hemodynamics in Systemic Sclerosis Patients Evaluated By Laser Doppler Flowmetry
Background/Purpose Iloprost is a milestone in the treatment of Raynaud’s Phenomenon (RP). However, it has transient hemodynamic effects due to a very short half-time, thereby…Abstract Number: 1702 • 2014 ACR/ARHP Annual Meeting
Antiphospholipid Antibodies in Systemic Sclerosis: Prevalence and Clinical Significance?
Background/Purpose: Systemic Sclerosis (SSc) is an autoimmune disease characterized by collagen deposition and vascular changes of the skin and internal organs, leading ultimately to fibrosis. …Abstract Number: 1698 • 2014 ACR/ARHP Annual Meeting
Peripheral Blood Eosinophil Counts Increase in Patients with Systemic Sclerosis and Associated with Its Disease Severity
Background/Purpose : Increased levels of serum pro-fibrotic cytokines such as IL-4 and IL-13 and plasma CXCL4 have been previously reported in patients with systemic sclerosis…Abstract Number: 1697 • 2014 ACR/ARHP Annual Meeting
High Frequency Skin Ultrasound Detects Subclinical Diffuse Dermal Involvement in Patients with Limited Cutaneous Systemic Sclerosis
Background/Purpose . The modified Rodnan’s skin score (mRSS) is the validated method to detect both severity and extension of skin involvement, and high frequency skin…Abstract Number: 1696 • 2014 ACR/ARHP Annual Meeting
Left Atrial Area Measurement Is Useful for Evaluating Left Ventricular Diastolic Dysfunction Coexisting with Pulmonary Arterial Hypertension Associated with Systemic Sclerosis
Background/Purpose: Pulmonary arterial hypertension (PAH) is a crucial organ involvement affecting survival of patients with connective tissue disease (CTDs), such as systemic sclerosis (SSc), systemic…Abstract Number: 1695 • 2014 ACR/ARHP Annual Meeting
Validation of Vesmeter As a Diagnostic Tool of Scleroderma
Background/Purpose: Objective method to evaluate the skin involvement in the patients with scleroderma has not been definitely established. We have developed Vesmeter, a computer-linked device…Abstract Number: 1694 • 2014 ACR/ARHP Annual Meeting
a Feasibility Study of Subjective and Objective Assessment of Sublingual Abnormalities in Systemic Sclerosis
Background/Purpose: Sublingual frenulum abnormalities are reported in systemic sclerosis (SSc), but the exact nature and clinical relevance of such abnormalities is unknown. Laser speckle contrast…Abstract Number: 1693 • 2014 ACR/ARHP Annual Meeting
Progressive Disease in Systemic Sclerosis after One Year of Follow-up; Results of a Standardized Multidisciplinary Health Care Program
Background/Purpose: The aim of this study is to evaluate disease course of systemic sclerosis (SSc) patients participating in a single centre multidisciplinary health-care program over…Abstract Number: 1692 • 2014 ACR/ARHP Annual Meeting
The Additive Value of Nailfold Videocapillaroscopy Patterns to Disease-Specific Autoantibodies in Discrimination of Patients with Systemic Sclerosis at Risk for Severe Organ Involvement
Background/Purpose: Severe nailfold videocapillaroscopy (NVC) patterns in patients with systemic sclerosis (SSc) are associated with a high risk of organ involvement. SSc-specific autoantibodies seem to…Abstract Number: 1691 • 2014 ACR/ARHP Annual Meeting
Systemic Sclerosis Patients with Pulmonary Hypertension Have a Lower Change in End Tidal Carbon Dioxide Following Three Minutes of Step Exercise Than Systemic Sclerosis Patients without Pulmonary Hypertension: A Cross-Sectional Study
Background/Purpose: Pulmonary hypertension (PH) is a leading cause of death in patients with systemic sclerosis (SSc). Transthoracic echocardiogram and pulmonary function testing are standard noninvasive…Abstract Number: 1689 • 2014 ACR/ARHP Annual Meeting
Microhaemorrages and Giant Capillaries in Nailfold Videocapillariscopies Are Able to Accurately Predict Disease Activity Level in Systemic Sclerosis
Background/Purpose Systemic Sclerosis (SSc) is a connective tissue disease characterized by Raynaud’s phenomenon, skin fibrosis and involvement of internal organs such as lung, heart, bowel,…Abstract Number: 1676 • 2014 ACR/ARHP Annual Meeting
Physical Therapy for Systemic Sclerosis: Systematic Review and Meta-Analysis
Background/Purpose Physical therapy and rehabilitation are often recommended to improve function in patients with systemic sclerosis (SSc), but a systematic review of the evidence supporting…Abstract Number: 1675 • 2014 ACR/ARHP Annual Meeting
Regional Implantation of Adipose Tissue-Derived Cells Induces a Prompt Healing of Long-Lasting Indolent Digital Ulcers in Patients with Systemic Sclerosis
Background/Purpose Fingertip digital ulcers (DUs) are a rather frequent and invalidating complication in the course of systemic sclerosis (SSc), often showing a very slow or…