ACR Meeting Abstracts

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  • Abstract Number: 0308 • ACR Convergence 2023

    Burden of Osteoarthritis Attributable to High BMI in 38 OECD Countries: A Benchmarking Analysis

    Dhruvkumar Gadhiya1, Utsav Patel2, Hiren Chhayani3, Krushi Shah3, Sneh Patel3, Victor Adedara4, Divya Patel3 and Hardik Desai5, 1St.Luke's University Health, Anderson Campus, Easton, PA, 2Tulane University, New Orleans, LA, 3G.M.E.R.S. Medical College, Gandhinagar, Gandhinagar, India, 4St George’s University SOM, True Blue Greneda, True Blue, Grenada, 5Gujarat Adani Institute of Medical Sciences, Bhuj, India., Bhuj, India

    Background/Purpose: The burden of osteoarthritis related to high body mass index (BMI) in OECD countries is a significant public health concern. Osteoarthritis is strongly associated…
  • Abstract Number: 0378 • ACR Convergence 2023

    Characteristics of Macrophage Activation Syndrome in Systemic JIA Patients Receiving Anakinra as First-line Treatment

    Remco Erkens1, Laura Huber1, Anouk Verwoerd1, Greta Rogani1, Dieneke Schonenberg-Meinema2, Merlijn van den Berg2, Wineke Armbrust3, Elizabeth Legger4, Sylvia Kamphuis5, Ellen Schatorjé6, Esther Hoppenreijs7, Joost Swart8, Marc Jansen1, Jorg van Loosdregt1 and Sebastiaan Vastert1, 1University Medical Center Utrecht, Utrecht, Netherlands, 2Emma Children's Hospital, Amsterdam University Medical Centers, Amsterdam, Netherlands, 3University Medical Hospital Groningen, Groningen, Netherlands, 4University Medical Center Groningen, Groningen, Netherlands, 5Erasmus University Medical Center, Department of Pediatric Rheumatology, Rotterdam, Netherlands, 6University Medical Center Radboud, Nijmegen, Netherlands, 7Radboud University Medical Center, Nijmegen, Netherlands, 8Wilhelmina Children's Hospital / UMC Utrecht, Utrecht, Netherlands

    Background/Purpose: Systemic Juvenile Idiopathic Arthritis (sJIA) is a severe inflammatory disease with auto-inflammatory characteristics. The introduction of targeted biologic therapies has revolutionized the treatment and…
  • Abstract Number: 0387 • ACR Convergence 2023

    The Association Between Inflammation, High-Sensitivity Cardiac Troponin T, and Cardiovascular Events in Rheumatoid Arthritis

    Brittany Weber1, Dana Weisenfeld1, Mary Jeffway1, Jonathan Coblyn1, Michael Weinblatt2, Nancy Shadick3, Marcelo DiCarli1 and Katherine Liao1, 1Brigham and Women's Hospital, Boston, MA, 2Harvard Medical School, Waban, MA, 3Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Patients with rheumatoid arthritis (RA) have a 1.5x excess risk of cardiovascular (CV) disease compared to the general population, attributed to chronic inflammation. In…
  • Abstract Number: 0390 • ACR Convergence 2023

    Statins Influence the Relationship Between ATP-binding Cassette Transporter A1 (ABCA1)-mediated Cholesterol Efflux and Coronary Atherosclerosis in Rheumatoid Arthritis

    George Karpouzas1, Bianca Papotti2, Sarah Ormseth3, Marcella Palumbo2, Elizabeth Hernandez3, Maria Pia Adorni4, Francesca Zimetti2, Matthew Budoff1 and Nicoletta Ronda2, 1Harbor-UCLA Medical Center, Torrance, CA, 2University of Parma, Department of Food and Drug, Parma, Italy, 3The Lundquist Institute, Torrance, CA, 4Department of Medicine and Surgery, Unit of Neuroscience, University of Parma, Parma, Italy

    Background/Purpose: Cholesterol efflux capacity (CEC) is the main antiatherogenic function of high-density lipoprotein (HDL). ATP-binding-cassette A1 (ABCA1) membrane transporter initiates cholesterol export from arterial macrophages…
  • Abstract Number: 0394 • ACR Convergence 2023

    Higher Intakes of Red Meat Are Associated with an Increased Risk of Developing Seropositive but Not Seronegative Rheumatoid Arthritis – Results from a Nested Case-Control Study

    Rebecka Teresia Bäcklund1, Isabel Drake1, Ulf Bergström1, Michele Compagno2, Emily Sonestedt1 and Carl Turesson1, 1Lund University, Malmö, Sweden, 2Lund University, Lund, Sweden

    Background/Purpose: Healthy eating habits might prevent the development of rheumatoid arthritis (RA). We aimed to examine the relation between adherence to dietary recommendations and the…
  • Abstract Number: 0338 • ACR Convergence 2023

    Comparative Disease Burden in Patients with Rheumatoid Arthritis, Psoriatic Arthritis or Ankylosing Spondylitis: Data from COVAD Patient-reported E-survey

    Diego Benavent1, Marco Fornaro2, Florenzo Iannone3, Lorenzo Cavagna4, Masataka Kuwana5, Naveen R6, Vishwesh Agarwal7, Jessica Day8, Mrudula Joshi9, Sreoshy Saha10, Kshitij Jagtap11, Wanruchada Katchamart12, Phonpen Akarawatcharangura Goo13, Binit Vaidya14, Tsvetelina Velikova15, Parikshit Sen16, Samuel Shinjo17, Ai Lyn Tan18, Nelly Ziade19, Marcin Milchert20, Abraham Edgar Gracia-Ramos21, Carlo Caballero22, Hector Chinoy23, Vikas Agarwal6, Rohit Aggarwal24, Latika Gupta25 and Vincenzo Venerito26, 1Hospital la Paz, Madrid, Spain, 2University of Bari, Grottaglie, Italy, 3Rheumatology Unit, Department of Precision and Regenerative Medicine and Ionian Area, University of Bari "Aldo Moro", Bari, Italy, 4Fondazione IRCCS Policlinico San Matteo, Pavia, Italy, 5Nippon Medical School Graduate School of Medicine, Tokyo, Japan, 6Sanjay Gandhi Postgraduate Institute of Medical Sciences (SGPGIMS), Lucknow, India, 7Mahatma Gandhi Missions Medical College, Lucknow, India, 8Walter and Eliza Hall Institute, Melbourne, Australia, 9Byramjee Jeejeebhoy Government Medical College and Sassoon General Hospitals, Pune, India, 10Mymensingh Medical College, Faridpur, Bangladesh, 11Seth Gordhandhas Sunderdas Medical College and King Edwards Memorial Hospital, Mumbai, India, 12Mahidol University, Bangkok, Thailand, 13Department of Medicine, Queen Savang Vadhana Memorial Hospital, Chonburi, Thailand, 14National Center for Rheumatic Diseases (NCRD), Ratopul, Kathmandu, Nepal., Kathmandu, India, 15Department of Clinical Immunology, Medical Faculty, University Hospital "Lozenetz", Sofia University St. Kliment Ohridski, Sofia, Bulgaria, 16Maulana Azad Medical College, 2-Bahadurshah Zafar Marg, New Delhi, Delhi-110002, India., Dalhi, India, 17Faculdade de Medicina FMUSP, Universidade de Sao Paulo, São Paulo, Brazil, 18University of Leeds, Leeds, United Kingdom, 19Saint-Joseph University, Beirut, Lebanon, 20Department of Internal Medicine, Rheumatology, Diabetology, Geriatrics and Clinical Immunology, Pomeranian Medical University in Szczecin, Szczecin, Poland, 21Department of Internal Medicine, General Hospital, National Medical Center "La Raza", Instituto Mexicano del Seguro Social, Av. Jacaranda S/N, Col. La Raza, Del. Azcapotzalco, C.P. 02990, Mexico City, Mexico, 22Universidad del Norte, Barranquilla, Colombia, 23The University of Manchester, Sale, United Kingdom, 24University of Pittsburgh, Pittsburgh, PA, 25Royal Wolverhampton Trust, Wolverhampton/University of Manchester, United Kingdom, 26Rheumatology Department, Università degli Studi di Bari, Bari, Italy

    Background/Purpose: Rheumatoid arthritis (RA) and spondyloarthritis (SpA), including either Psoriatic Arthritis (PsA) and Ankylosing Spondylitis (AS), are some of the most commonly diagnosed autoimmune rheumatic…
  • Abstract Number: 0344 • ACR Convergence 2023

    Patient Engagement and Adherence to Digital Study Tasks: WEARable Activity Tracker Study Exploring Rheumatoid Arthritis Patients’ Disease Activity Using Patient-Reported Outcome Measures, Clinical Measures, and Biometric Sensor Data (the WEAR Study)

    W. Benjamin Nowell1, Cassie Clinton2, Fenglong Xie2, Yuji Su3, Laura Stradford1, David Curtis4, Patrick Zueger5, Pankaj Patel6, Kelly Gavigan7, Shilpa Venkatachalam8, Esteban Rivera9 and Jeffrey R. Curtis3, 1Global Healthy Living Foundation, Nyack, NY, 2University of Alabama at Birmingham, Birmingham, AL, 3University of Alabama at Birmingham and Illumination Health, Birmingham, AL, 4Global Healthy Living Foundation, San Francisco, CA, 5AbbVie, Inc., Mettawa, IL, 6AbbVie, Inc., North Chicago, IL, 7Global Healthy Living Foundation, Upper Nyack, NY, 8Global Healthy Living Foundation, New York, NY, 9Global Healthy Living Foundation, Long Island City, NY

    Background/Purpose: We evaluated participants' adherence to protocol-assigned capture of patient-reported outcomes (PROs) and activity tracker data in the context of an ongoing longitudinal study collecting…
  • Abstract Number: 0340 • ACR Convergence 2023

    Rheumatology Patients’ Experiences of a Nationwide Transition to an Adalimumab Biosimilar: A Cross-Sectional Study

    Chiara Gasteiger1, Maria Lobo2, Robin Stanley1, Lun Shen Wong1, Rachel Murdoch1 and Nicola Dalbeth1, 1University of Auckland, Auckland, New Zealand, 2Department of Rheumatology, Te Toka Tumai Auckland, Auckland, New Zealand

    Background/Purpose: Patients are frequently transitioned to biosimilars to reduce the cost burden of biologics. Brand changes can be daunting for patients who have concerns about…
  • Abstract Number: 0351 • ACR Convergence 2023

    Needs Assessment Survey of Critical Data Element Completion in Telemedicine Visits for Juvenile Idiopathic Arthritis in the Post-Pandemic Period

    Kristen Hayward1, Y. Ingrid Goh2, Mary Toth3, Jenny Leal4, Alice Liu5, Nidji Naik5, Jade Singleton5, Jackson Youn5 and Esi Morgan5, 1Seattle Children's Hospital/University of Washington School of Medicine, Seattle, WA, 2The Hospital for Sick Children, Toronto, ON, Canada, 3Nemours Foundation, Orlando, FL, 4Nationwide Children's, Columbus, OH, 5Seattle Children's Hospital, Seattle, WA

    Background/Purpose: Juvenile Idiopathic Arthritis (JIA) affects 1 in 1,000 children in the United States (US). There is a shortage of pediatric rheumatologists across North America…
  • Abstract Number: 0276 • ACR Convergence 2023

    Disease Control in Patients with Monogenetic Autoinflammatory Diseases Under Canakinumab Treatment – Comparison of 30 Months Interim Data from the RELIANCE Registry

    Ivan Foeldvari1, Tilmann Kallinich2, Norbert Blank3, Joerg Henes4, Birgit Kortus-Goetze5, Prasad T. Oommen6, Anne Pankow7, Tobias Krickau8, Catharina Schuetz9, Gerd Horneff10, Juergen Rech11, Frank Weller-Heinemann12, Ales Janda13, Markus Hufnagel14, Florian M. Meier15, Frank Dressler16, Michael Borte17, Ioana Andreica18, Peter Wasiliew19, Michael Fiene20, Daniel Windschall21, Martin Krusche22, Tania Kuempfel23, Julia Weber-Arden24 and Jasmin B. Kuemmerle-Deschner25, 1Hamburger Zentrum für Kinder- und Jugendrheumatologie, Hamburg, Germany, 2Department of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, Charité Universitätsmedizin Berlin, Nuremberg, Germany, 3University Hospital Heidelberg, Heidelberg, Germany, 4University Hospital Tuebingen, Tuebingen, Germany, 5Department of Internal Medicine, Division of Nephrology,University Hospital of Giessen and Marburg, Marburg, Germany, 6Department of Pediatric Oncology, Hematology and Clinical Immunology, Center for Child and Adolescent Health,Medical Faculty Heinrich-Heine-University Duesseldorf, Duesseldorf, Germany, 7Department of Rheumatology and Clinical Immunology,Charité-Universitätsmedizin Berlin, Berlin, Germany, 8Pediatrics, Friedrich-Alexander University Erlangen-Nuernberg (FAU), Erlangen, Germany, 9Department of Pediatrics, Medizinische Fakultät Carl Gustav Carus,Technische Universität Dresden, Dresden, Germany, 10Asklepios Klinik Sankt Augustin GmbH, Bonn, Germany, 11University Clinic Erlangen, Erlangen, Germany, 12Division of Pediatric Rheumatology, Prof. Hess Children's Hospital, Bremen, Bremen, Germany, 13Department of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany, 14Division of Pediatric Infectious Diseases and Rheumatology, Department of Pediatrics and Adolescent Medicine, University Medical Center, Medical Faculty, University of Freiburg, Freiburg, Germany, 15Department of General Pharmacology and Toxicology, Goethe University Hospital and Goethe University Frankfurt, Frankfurt am Main, Germany, 16Department of Paediatric Pneumology, Allergology and Neonatology, Children's Hospital, Hannover Medical School, Hannover, Germany, 17Hospital for Children & Adolescents, St. Georg Hospital, Leipzig, Germany, 18Rheumazentrum Ruhrgebiet Herne, Herne, Germany, 19Division of Pediatric Rheumatology and autoinflammation reference center Tuebingen, Department of Pediatrics, University Hospital Tuebingen, Tuebingen, Germany, 20Rheumatology Center Greifswald, Greifswald, Germany, 21Clinic of Paediatric and Adolescent Rheumatology, St. Josef-Stift Sendenhorst, Northwest German Center for Rheumatology, Sendenhorst, Germany, 22UKE, Hamburg, Germany, 23Institute of Clinical Neuroimmunology, Biomedical Center and University Hospital, Ludwig-Maximilians Universität München, Muenchen, Germany, 24Novartis Innovative Medicines, Nuernberg, Germany, 25med.uni-tuebingen, Tübingen, Germany

    Background/Purpose: Treatment of autoinflammatory periodic diseases (AID) with the interleukin-1β inhibitor canakinumab (CAN) has been shown to be safe and effective in controlled trials and…
  • Abstract Number: 0361 • ACR Convergence 2023

    Safety of Golimumab Dose Escalation in Pediatric Autoimmunity: A Single Institution Retrospective Experience

    Leah Medrano and Alice Hoftman, David Geffen School of Medicine, UCLA, Los Angeles, CA

    Background/Purpose: There is limited data on pediatric golimumab dose escalation, with some data available only in the adult literature. The subcutaneous formulation is not approved…
  • Abstract Number: 0364 • ACR Convergence 2023

    Sex Differences in Clinical and Imaging Characteristics of Axial Juvenile Spondyloarthritis

    Adam Mayer1, Timothy G. Brandon2, Pamela F. Weiss3 and on behalf of the JAXSPERT members2, 1University of Pennsylvania/Children's Hospital of Philadelphia, Philadelphia, PA, 2Children's Hospital of Philadelphia, Philadelphia, PA, 3Children's Hospital of Philadelphia, Philadelphia, PA

    Background/Purpose: The extent to which heterogeneity exists in youth with axial disease and juvenile spondyloarthritis (JSpA) is unclear. In a cross-sectional sample of patients classified…
  • Abstract Number: 0369 • ACR Convergence 2023

    Trajectory of Progression in Transition Readiness in Adolescents with JIA and jSLE

    Dorota Borovsky1, Lauren Heessels1, Tania Cellucci2, Liane Heale1, Julie Herrington1, KAREN BEATTIE1 and Michelle Batthish2, 1McMaster University, Hamilton, ON, Canada, 2McMaster Children's Hospital, Hamilton, ON, Canada

    Background/Purpose: For adolescents, the transition from pediatric to adult rheumatology care is associated with increased health risks, poor disease control and loss to follow-up. Optimizing…
  • Abstract Number: 0371 • ACR Convergence 2023

    Assessing Methotrexate Adherence in JIA Using Electronic Health Record-Linked Pharmacy Dispensing Data

    Dori Abel1, David Anderson1, Michael Kallan2, Levon Utidjian1, Joyce Chang3, Chen Kenyon1 and Sabrina Gmuca1, 1Children's Hospital of Philadelphia, Philadelphia, PA, 2University of Pennsylvania, Philadelphia, PA, 3Boston Children's Hospital, Boston, MA

    Background/Purpose: The extent to which lack of adherence to prescribed treatment regimens contributes to differential disease outcomes in JIA – and demographic disparities in these…
  • Abstract Number: 0300 • ACR Convergence 2023

    Nailfold Videocapillaroscopy in Idiopathic Inflammatory Myopathy Compared with Healthy Controls

    Megan Sullivan1, Maximiliano Diaz-Menindez2, Colleen T. Ball2, Benjamin Wang3 and Florentina Berianu1, 1Mayo Clinic Florida, Jacksonville, FL, 2Mayo Clinic Jacksonville, Jacksonville, FL, 3Mayo Clinic, Jacksonville, FL

    Background/Purpose: Idiopathic inflammatory myopathies (IIMs) are a group of autoimmune disorders that cause inflammation of the muscle. This includes dermatomyositis and polymyositis. Literature has been…
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