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  • Abstract Number: 2582 • 2014 ACR/ARHP Annual Meeting

    Serum Levels of Bone Morphogenetic Protein-7 and Sclerostin Are Elevated in Ankylosing Spondylitis, but Not Linked with Structural Damage

    Weiping Kong1, Xiaotong WANG1, Tongliang Zhou2, Yue Jin3, Qingwen TAO1, Yuan Xu1, Yingze Zhang1, Jianming WANG1 and Xiaoping Yan1, 1Department of TCM Rheumatology, China-Japan Friendship Hospital, BEIJING, China, 2CLINICAL RESEARCH INSTITUTE OF IMMUNOLOGY, China-Japan Friendship Hospital, BEIJING, China, 3COMBINATION OF WESTERN AND CHINESE MEDICINE, Beijing University of Chinese Medicine, BEIJING, China

    Background/Purpose Ankylosing spondylitis (AS) is a chronic inflammatory disease characterized by new bone formation that progressively leads to ankylosis and functional disability. The mechanisms of…
  • Abstract Number: 2581 • 2014 ACR/ARHP Annual Meeting

    Clinically Active Non-Radiographic Axial Spondyloarthritis Patients Who Initially Have a Negative MRI and Normal CRP May Develop a Positive MRI or Elevated CRP at a Later Timepoint

    Xenofon Baraliakos1, Joachim Sieper2, Su Chen3, Aileen L. Pangan3 and Jaclyn K. Anderson3, 1Rheumazentrum Ruhrgebiet, Herne, Germany, 2Charité Universitätsmedizin Berlin, Berlin, Germany, 3AbbVie Inc., North Chicago, IL

    Background/Purpose: Patients (pts) with non-radiographic axial spondyloarthritis (nr-axSpA) and active disease may have objective evidence of inflammation, either as bone marrow edema (BME) on magnetic…
  • Abstract Number: 2580 • 2014 ACR/ARHP Annual Meeting

    A Comparison of Baseline Characteristics and Real-Life Effectiveness of Anti-TNF Therapy in Non-Radiographic Axial Spondyloarthritis Versus Ankylosing Spondylitis – a Single Center Cohort Study

    Sarka Forejtova1, Jakub Zavada2, Michal Uher3, Karel Hejduk3 and Karel Pavelka4, 1Rheumatology, Institute of Rheumatology, Prague, Czech Republic, 2Charles University, Prague, Czech Republic, 3Institute of Biostatistics and Analyses, Masaryk University, Brno, Czech Republic, 4Institute of Rheumatology and Department of Rheumatology, 1st Faculty of Medicine, Charles University in Prague, Prague, Czech Republic

    Background/Purpose: The recent Assessment of SpondyloArthritis international Society (ASAS) classification criteria proposed the concept of axial spondylarthritis (axSpA) to enable earlier treatment not only for…
  • Abstract Number: 2579 • 2014 ACR/ARHP Annual Meeting

    How Should We Calculate the ASDAS If the Conventional C-Reactive Protein Is below the Limit of Detection? – an Analysis in the DESIR Cohort

    Pedro Machado1,2, Victoria Navarro-Compán1,3, Robert Landewé4,5, Floris van Gaalen1, Christian Roux6 and Desirée van der Heijde1, 1Leiden University Medical Center, Leiden, Netherlands, 2University College London, London, United Kingdom, 3University Hospital La Paz, Madrid, Spain, 4Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands, 5Atrium Medical Center, Heerlen, Netherlands, 6Paris Descartes University, Cochin Hospital, Paris, France

    Background/Purpose: The Ankylosing Spondylitis Disease Activity Score (ASDAS) is a composite measure of disease activity in axial spondyloarthritis. It  was  suggested  that  when  the  conventional …
  • Abstract Number: 2578 • 2014 ACR/ARHP Annual Meeting

    Disease Activity Is the Major Determinant of Quality of Life and Physical Function in Patients with Early Axial Spondyloarthritis. Results from the Esperanza Cohort.

    Cristina Fernández-Carballido1, Victoria Navarro-Compán2, Mireia Moreno3, Xavier Juanola4, Juan Mulero5 and Eugenio De Miguel6, 1Rheumatology, University General Hospital Elda, Elda (Alicante), Spain, 2Rheumatology, University Hospital La Paz and Leiden University Medical Center, Madrid, Spain, 3Rheumatology, University Hospital Parc Taulí, Sabadell, Spain, 4Rheumatology, University Hospital Bellvitge, Barcelona, Spain, 5Rheumatology, University Hospital Puerta de Hierro, Majadahonda (Madrid), Spain, 6Rheumatology, University Hospital La Paz - IdiPaz, Madrid, Spain

    Background/Purpose : Main objective: to describe health related quality of life (HRQoL), physical function (PF) and spinal mobility (SM) in patients with early axial Spondyloarthritis…
  • Abstract Number: 2577 • 2014 ACR/ARHP Annual Meeting

    The Ankylosing Spondylitis Disease Activity Score More Closely Reflects MRI Parameters of Sacroiliitis Than the Bath Ankylosing Spondylitis Disease Activity Index in Patients with Non-Radiographic Axial Spondyloarthritis

    Walter P. Maksymowych1, S Wichuk1, H Jones2, A Szumski3, L Marshall2, J Bukowski2 and RG Lambert4, 1Department of Medicine, University of Alberta, Edmonton, AB, Canada, 2Pfizer Inc., Collegeville, PA, 3Specialty Care, Pfizer Inc., Collegeville, PA, 4Radiology, University of Alberta, Edmonton, AB, Canada

    Background/Purpose: Validation of clinical measures of disease in non-radiographic axial SpA (nr-axSpA) has been limited, especially using inflammatory and structural lesions on MRI as gold…
  • Abstract Number: 2576 • 2014 ACR/ARHP Annual Meeting

    Diffusing Weight Magnetic Resonance Imaging May Suggest the Treatment Strategy in Ankylosing Spondylitis

    Sang-Yeob Lee, Division of Rheumatology, Department of Internal Medicine, Dong-A University College of Medicine, Busan, South Korea

    Background/Purpose: With the advanced MRI techniques, pathologic features can be detected at an early stage and quantitatively evaluated, resulting in the advantages of early diagnosis…
  • Abstract Number: 2575 • 2014 ACR/ARHP Annual Meeting

    Validation of the RAPID-3 Questionnaire in a Cohort of Patients with Axial Spondyloarthritis

    Maria Celeste Orozco1, Luis Alejandro Cayetti2, Emilce Schneeberger3, Natalia Zamora4, Fernando Andres Sommerfleck1 and Gustavo Citera2, 1Rheumatology, Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, 2Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, 3Instituto de Rehabilitacion Psicofisica, Buenos Aires, Argentina, 4IREP, Echeverría 955, Buenos Aires, Argentina

    Background/Purpose: RAPID3(Routine Assessment of Patient Index Data 3)  is a simple index which was developed initially for RA but has been reported informative and many…
  • Abstract Number: 2574 • 2014 ACR/ARHP Annual Meeting

    Do Patients with Axial Spondyloarthritis (AxSpA) Perform Enough Physical Activity? a Cross-Sectional Study of 207 Patients

    Stephanie Fabre1,2, Anna Molto2, Sabrina Dadoun2, Christopher Rein2, Christophe Hudry2, Sarah Kreis2, Bruno Fautrel2, Edouard Pertuiset1 and Laure Gossec2, 1Rheumatology, René Dubos Hospital, Pontoise, France, 2Rheumatology, UPMC GRC08, Paris 06 University, Pitié Salpétrière Hospital, Paris, France

    Background/Purpose Regular exercise is considered a cornerstone of AxSpA treatment, together with medication. Little data are available regarding the level and type of physical activity…
  • Abstract Number: 2593 • 2014 ACR/ARHP Annual Meeting

    Patients with Non-Radiographic Axial Spondyloarthritis and Ankylosing Spondylitis Demonstrate the Same Clinical Disease Course over Two Years: Results from the Gespic Cohort

    Denis Poddubnyy1, Hildrun Haibel1, Jürgen Braun2, Martin Rudwaleit1 and Joachim Sieper1, 1Charité Universitätsmedizin Berlin, Berlin, Germany, 2Rheumazentrum Ruhrgebiet, Herne, Germany

    Background/Purpose In cross-sectional studies it has been demonstrated that non-radiographic axial spondyloarthritis (nr-axSpA) does not differ from ankylosing spondylitis (AS) with respect to clinical signs…
  • Abstract Number: 2591 • 2014 ACR/ARHP Annual Meeting

    Effects of Self-Management Model on the Disease-Related Knowledge, Joint Function and Quality of Life in Patients with Ankylosing Spondylitis

    Pingping Zhang1, Jun Qi2, Zhiming Lin3, Minjing Zhao2 and Jieruo Gu4, 1Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, China, 2The Third Affiliated Hospital of Sun Yat-sen University, guangzhou, China, 3The Affiliated Third Hospital of Sun Yat-san University, Rheumatology, Guangzhou, China, 4Rheumatology, The Affiliated Third Hospital of Sun Yat-san University, Rheumatology, Guangzhou, China

    Background/Purpose: Ankylosing spondylitis is a kind of chronic inflammatory diseases, inflammation of the sacroiliac joint and spine attachment points are the main symptoms , as a kind…
  • Abstract Number: 2592 • 2014 ACR/ARHP Annual Meeting

    Assessment of Spondyloarthritis International Society Endorsed Recommendations for Early Referral of Patients Suspected for Axial Spondyloarthritis

    Denis Poddubnyy1, Astrid van Tubergen2, Robert Landewé3, Joachim Sieper1 and Désirée van der Heijde4, 1Charité Universitätsmedizin Berlin, Berlin, Germany, 2Maastricht University Medical Center, Maastricht, Netherlands, 3Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands, 4Leiden University Medical Center, Leiden, Netherlands

    Background/Purpose There is a substantial gap of 5 to 8 years between the onset of symptoms (usually back pain) and the diagnosis of axial spondyloarthritis…
  • Abstract Number: 2590 • 2014 ACR/ARHP Annual Meeting

    Comparison of Radiographic Damage Score in Ankylosing Spondylitis According to Tumor Necrosis Factor Inhibitor: Observation Study of Korean Spondyloarthropathy Registry (OSKAR) Data

    Tae-Jong Kim1, JI Hui SHIN2, Il-Hoon Sung3, Seunghun Lee4, Kyung-Bin Joo5 and Tae-Hwan Kim6, 1Chonnam Nat`l University Medical School&Hospital, Gwangju, South Korea, 2Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 3Orthopaedic surgery, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 4Department of Radiology, Department of Radiology, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea, 5Department of Radiology, Department of Radiology, Hanynag University Hospital for Rheumatic Diseases, Seoul, South Korea, 6Division of Rheumatology, Department of Internal Medicine, Hanyang University Hospital for Rheumatic Diseases, Seoul, South Korea

    Background/Purpose To evaluate the influence of tumor necrosis factor (TNF) blocker on the radiographic damage in ankylosing spondylitis (AS).  Methods . A total of 610…
  • Abstract Number: 2589 • 2014 ACR/ARHP Annual Meeting

    EULAR Recommendations for the Use of Imaging in Spondyloarthritis in Clinical Practice

    Peter Mandl1, Victoria Navarro-Compán2, Pauline Bakker3, Lene Terslev4, Philippe Aegerter5, Désirée van der Heijde3, Maria-Antonietta d'Agostino6, Xenofon Baraliakos7, Susanne Juhl Pedersen8, Anne G. Jurik9, Esperanza Naredo10, Claudia Schueller-Weidekamm11, Ulrich Weber12, Marius Wick13, Emilio Filippucci14, Philip G. Conaghan15, Martin Rudwaleit16, Georg A. Schett17, Joachim Sieper16, Simon Tarp18, Helena Marzo-Ortega15 and Mikkel Ostergaard4, 1Division of Rheumatology, Medical University of Vienna, Vienna, Austria, 2Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 3Leiden University Medical Center, Leiden, Netherlands, 4Copenhagen University Hospital at Glostrup, Copenhagen, Denmark, 5Epidemiology, Versailles-Saint Quentin en Yvelines University- APHP, Ambroise-Paré Hospital,, Boulogne-Billancourt,, France, 6Rheumatology, Versailles-Saint Quentin en Yvelines University, Boulogne-Billancourt, France, 7Rheumazentrum Ruhrgebiet, Herne, Germany, 8Dept. of Rheumatology, Copenhagen Center for Arthritis Research, Copenhagen, Denmark, 9Department of Radiology, Aarhus University Hospital, Aarhus, Denmark, 10Rheumatology, Hospital General Universitario Gregorio Marañón, Madrid, Spain, 11Department of Radiology, Medical University of Vienna, Vienna, Austria, 12University of Alberta, Edmonton, AB, Canada, 13Karolinska University Hospital, Stockholm, Sweden, 14Department of Rheumatology, University of Ancona, Jesi, Italy, 15University of Leeds and NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds, United Kingdom, 16Charité Universitätsmedizin Berlin, Berlin, Germany, 17Dept of Medicine 3, Rheumatology and Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, 18Copenhagen University Hospital at Fredriksberg, Copenhagen, Denmark

    Background/Purpose: Reflecting the perceived need for developing evidence-based recommendations on the use of imaging of the joints in the clinical management of spondyloarthritis (SpA) a…
  • Abstract Number: 2588 • 2014 ACR/ARHP Annual Meeting

    Which Characteristics of Inflammatory Back Pain (CBP) Forecast the Presence of HLA-B27? Results from the Esperanza Cohort

    Victoria Navarro-Compán1, Juan Jose Aznar2, Luis F Linares3, Eduardo Collantes-Estévez4, Robert B. M. Landewé5, Désirée van der Heijde6 and Pedro Zarco7, 1Rheumatology, University Hospital La Paz and Leiden University Medical Center, Madrid, Spain, 2Hospital de Mérida, Mérida (Badajoz), Spain, 3University Hospital Virgen de la Arrixaca, Murcia, Spain, 4IMIBIC/University Hospital Reina Sofía, Córdoba, Spain, Córdoba, Spain, 5Department of Rheumatology, Amsterdam Rheumatology Center, Amsterdam, Netherlands, 6Leiden University Medical Center, Leiden, Netherlands, 7Rheumatology Department, Fundación Hospital Alcorcon, Alcorcon, Madrid, Spain

    Background/Purpose: CBP is often the starting point for a suspicion of axSpA. In the ASAS-criteria for axial SpA either MRI of the SI-joints or HLA-B27-testing…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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