Abstracts Archive - Page 1833 of 2425 - ACR Meeting Abstracts

Abstract Number: 2160 • 2015 ACR/ARHP Annual Meeting
The Role of Ultrasound Compared to Biopsy of Temporal Arteries in the Diagnosis and Treatment of Giant Cell Arteritis: A Diagnostic Accuracy and Cost-Effectiveness Study
Raashid Luqmani¹, Ellen Lee², Surjeet Singh³, Michael Gillett², Wolfgang A. Schmidt⁴, Mike Bradburn², Bhaskar Dasgupta^5,6, Andreas P Diamantopoulos⁷, Wulf Forrester-Barker⁸, William Hamilton⁹, Shauna Masters¹⁰, Brendan McDonald¹¹, Eugene McNally⁸, Colin T. Pease¹², Jennifer Piper⁸, John Salmon¹³, Allan Wailoo², Konrad Wolfe¹⁴, Andrew Hutchings¹⁵ and TABUL Study group, ¹Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom, ²School of Health and Related Research, University of Sheffield, Sheffield, United Kingdom, ³1Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom, ⁴Medical Center for Rheumatology and Clinical Immunology Berlin-Buch, Immanuel Krankenhaus Berlin, Berlin, Germany, ⁵Rheumatology, Southend University Hospital, Essex, United Kingdom, ⁶Southend University Hospital, Essex, United Kingdom, ⁷Rheumatology, Hospital of Southern Norway Trust, Kristiansand, Norway, ⁸Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom, ⁹Primary Care, University of Exeter, Exeter, United Kingdom, ¹⁰Nuffield Department of Orthopaedics Rheumatology and Musculoskeletal Science, University of Oxford, Oxford, United Kingdom, ¹¹Department of Neuropathology and Ocular Pathology, Oxford University Hospitals NHS Trust, Oxford, United Kingdom, ¹²Rheumatology, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, ¹³Ophthalmology, Oxford University Hospitals NHS Trust, Oxford, United Kingdom, ¹⁴Department of Pathology, Southend University Hospital, Essex, United Kingdom, ¹⁵Health Services Research Unit, London School of Hygiene and Tropical Medicine, London, United Kingdom
Background/Purpose: Giant cell arteritis (GCA) is a relatively common form of primary systemic vasculitis which if untreated can lead to permanent sight loss. It is…
Abstract Number: 2161 • 2015 ACR/ARHP Annual Meeting
Ustekinumab for the Treatment of Refractory Giant Cell Arteritis
Richard Conway^1,2, Lorraine O'Neill^3,4, Eileen O'Flynn³, Geraldine M. McCarthy^5,6, Conor Murphy⁷, Douglas J. Veale⁸, Ursula Fearon⁹ and Eamonn S. Molloy¹⁰, ¹CARD Newman Research Fellow, University College Dublin, Dublin, Ireland, ²Centre for Arthritis and Rheumatic Diseases, Dublin Academic Medical Centre, University College Dublin, Dublin, Ireland, ³Rheumatology, Dublin Academic Medical Centre, St. Vincent's University Hospital, Dublin, Ireland, ⁴Rheumatology, St. Vincent's University Hospital, Dublin 4, Ireland, ⁵Rheumatology, Mater Misericordiae University Hospital, Dublin 7, Ireland, ⁶University College Dublin, Dublin, Ireland, ⁷Department of Ophthalmology, Royal Victoria Eye and Ear Hospital, Dublin, Ireland, ⁸St Vincent's University Hospital, Centre for Arthritis and Rheumatic Diseases, Dublin Academic Medical Centre, Dublin 4, Ireland, ⁹St. Vincent's University Hospital, Centre for Arthritis and Rheumatic Diseases, Dublin Academic Medical Centre, Dublin 4, Ireland, ¹⁰St Vincent's University Hospital, Centre for Arthritis and Rheumatic Diseases, Dublin Academic Medical Centre, St Vincent's University Hospital, Dublin 4, Dublin 4, Ireland
Background/Purpose: Giant cell arteritis (GCA) requires treatment with high dose corticosteroids. Many patients require chronic steroid therapy with associated significant side effects. There is a…
Abstract Number: 2162 • 2015 ACR/ARHP Annual Meeting
Associations Between Education and Health Status Among Hispanics with Self-Reported Arthritis and/or Joint Pain
Leigha Vilen¹, Rebecca J. Cleveland², Alfredo Rivadeneira¹, Mary Altpeter³, Betsy Hackney⁴, Victoria Sepulveda² and Leigh F. Callahan⁴, ¹Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, ²University of North Carolina at Chapel Hill, Chapel Hill, NC, ³Institute on Aging, University of North Carolina at Chapel Hill, Chapel Hill, NC, ⁴Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC
Background/Purpose: Understanding the associations between education and health status among Hispanics with arthritis and/or joint pain is crucial in adapting existing arthritis interventions for this…
Abstract Number: 2163 • 2015 ACR/ARHP Annual Meeting
Associations Between Sex Differences, Pain, Insomnia, and Depression in Older Adults with Osteoarthritis: A Cross-Sectional Study
Minhui Liu¹, Susan McCurry¹, Michael Vitiello², Basia Belza¹ and Michael Von Korff³, ¹University of Washington School of Nursing, Seattle, WA, ²Psychiatry and Behavioral Sciences, Biobehavioral Nursing and Health Systems, University of Washington School of Medicine, Seattle, WA, ³Group Health Research Institute, Seattle, WA
Background/Purpose: Osteoarthritis (OA) is the most common form of arthritis and affects nearly 30 million Americans. Chronic pain is the major symptom in OA and…
Abstract Number: 2164 • 2015 ACR/ARHP Annual Meeting
Burden of Symptomatic Knee Osteoarthritis in the United States: Impact of Race/Ethnicity, Age and Sex
Bhushan Deshpande¹, Jeffrey N. Katz², Daniel H. Solomon², Edward H. Yelin³ and Elena Losina², ¹Orthopaedic and Arthritis Center for Outcomes Research, Brigham and Women's Hospital, Boston, MA, ²Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ³University of California, San Francisco, San Francisco, CA
Background/Purpose : Growing evidence suggests that the prevalence and incidence of knee OA is rising, partially due to increasing life expectancy and the growing obesity…
Abstract Number: 2165 • 2015 ACR/ARHP Annual Meeting
Awareness and Reasons for Lack of Post-Fracture Osteoporosis Therapy: A Survey of Post-Menopausal Women
Denise Boudreau¹, Onchee Yu¹, Akhila Balasubramanian², Jane Grafton¹, Heidi Wirtz³, Andreas Grauer³, D. Barry Crittenden³ and Delia Scholes¹, ¹Group Health Research Institute, Seattle, WA, ²Center for Observational Research, Amgen, Inc., Thousand Oaks, CA, ³Amgen Inc., Thousand Oaks, CA
Background/Purpose: Osteoporotic fractures cause patient morbidity and increase risk for future fracture. Effective drug therapies for osteoporosis (OP) are available, yet only a minority of…
Abstract Number: 2166 • 2015 ACR/ARHP Annual Meeting
Work Productivity in Newly Diagnosed, Untreated Rheumatoid Arthritis Patients
Siri Lillegraven¹, Nina P. Sundlisæter¹, Anna-Birgitte Aga¹, Inge C Olsen¹, Till Uhlig², Tore K. Kvien¹, Espen A. Haavardsholm¹ and The ARCTIC study group, ¹Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ²Diakonhjemmet Hospital, Oslo, Norway
Background/Purpose:Rheumatoid arthritis (RA) is a known cause of work productivity loss. The goal within rheumatology today is to diagnose RA as soon as possible, to…
Abstract Number: 2167 • 2015 ACR/ARHP Annual Meeting
Application of Combined Reporting of Benefit and Harm (OMERACT 3×3 methodology) to the Rheumatoid Arthritis Comparison of Active Therapies Trial
Maarten Boers^1,2, Sarah Leatherman³, James R. O'Dell⁴ and Jeffrey R. Curtis⁵, ¹Rheumatology, Amsterdam Rheumatology and immunology Center, VU University medical center, Amsterdam, Netherlands, ²Amsterdam Rheumatology and immunology Center, VU University Medical Center, Amsterdam, Netherlands, ³MAVERIC CSPCC (151MAV), VA Boston Healthcare System, Boston, MA, ⁴University of Nebraska Medical Center, Omaha, NE, ⁵Birmingham VAMC, Birmingham, AL
Background/Purpose: The Outcome Measures in Rheumatology (OMERACT) Initiative has suggested an analysis of the occurrence of benefit and harm in trials simultaneously, at the individual…
Abstract Number: 2168 • 2015 ACR/ARHP Annual Meeting
The Smoking Paradox in the Development of Myocardial Infarction Among Rheumatoid Arthritis Patients
Uyen Sa D.T. Nguyen¹, Yuqing Zhang², Na Lu³, Jingbo Niu⁴, David T. Felson⁴, Michael P. Lavalley⁵, Jeffrey A. Sparks⁶, Shun-Chiao Chang⁷, Elizabeth W. Karlson⁸ and Hyon K. Choi³, ¹Orthopedics and Physical Rehabilitation, University of Massachusetts Medical School, Worcester, MA, ²Clinical Epidemilogy and Training Unit, Boston University School of Medicine, Boston, MA, ³Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, ⁴Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ⁵Biostatistics, Boston University, Boston, MA, ⁶Division of Rheumatology, Immunology, and Allergy, Brigham & Women's Hospital, Boston, MA, ⁷Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ⁸Rheumatology, Brigham & Women's Hospital, Boston, MA
Background/Purpose: Smoking is a strong risk factor for myocardial infarction (MI), but not among rheumatoid arthritis (RA) patients. These paradoxical findings may be due to…
Abstract Number: 2169 • 2015 ACR/ARHP Annual Meeting
Low Education Is Associated with Mortality Among Individuals with Knee and/or Hip OA: The Johnston County Osteoarthritis Project
Rebecca J. Cleveland¹, Todd A. Schwartz², Jordan B. Renner³, Joanne M. Jordan⁴ and Leigh F. Callahan⁴, ¹University of North Carolina at Chapel Hill, Chapel Hill, NC, ²School of Nursing, University of North Carolina, Chapel Hill, NC, ³Radiology, University of North Carolina, Chapel Hill, NC, ⁴Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC
Background/Purpose: Low socioeconomic status (SES) is associated with an increased risk of death as well as knee and/or hip osteoarthritis (OA). SES and mortality has…
Abstract Number: 2170 • 2015 ACR/ARHP Annual Meeting
Sleep Efficiency and Cardiovascular Risk Burden in Rheumatoid Arthritis
Samannaaz S. Khoja¹, Gustavo J. Almeida², Mary Chester M. Wasko³ and Sara R. Piva², ¹Department of Physical Therapy, University of Pittsburgh, Pittsburgh, PA, ²Physical Therapy, University of Pittsburgh, Pittsburgh, PA, ³Lupus Center, Pittsburgh, PA
Background/Purpose: Sleep is an important physiological process responsible for regulating several metabolic and hormonal processes; hence, poor sleep may negatively impact health. Reduced sleep duration…
Abstract Number: 2171 • 2015 ACR/ARHP Annual Meeting
A Comparison of Maternal Outcomes in Women with and without Juvenile Idiopathic Arthritis
Debbie Ehrmann Feldman¹, Sasha Bernatsky², Evelyne Vinet³, Ciarán M. Duffy⁴, Elizabeth Hazel⁵, Garbis Meshefedjian⁶, Marie-Pierre Sylvestre⁷ and Anick Bérard¹, ¹Université de Montréal, Montréal, QC, Canada, ²Rheum/Clin. Epid., McGill MUHC/RVH, Montreal, QC, Canada, ³McGill University Health Centre, Montreal, QC, Canada, ⁴Children's Hospital of Eastern Ontario and University of Ottawa, Ottawa, ON, Canada, ⁵Rhematology, McGill University Health Centre, Montreal, QC, Canada, ⁶Public Health Department of Montreal, Montreal, QC, Canada, ⁷Université de Montréal, Montreal, QC, Canada
Background/Purpose: Although there is a higher frequency of adverse maternal outcomes in mother with rheumatoid arthritis, little is known regarding mothers with juvenile idiopathic arthritis…
Abstract Number: 2172 • 2015 ACR/ARHP Annual Meeting
Distribution of Clinical Osteoarthritis and Associations to Health-Related Quality of Life in a Population-Based Osteoarthritis Cohort
Guro Økelsrud Lombnæs¹, Karin Magnusson² and Kåre Birger Hagen¹, ¹National Advisory Unit on Rehabilitation in Rheumatology, Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ²Department of Rheumatology, National Advisory Unit on Rehabilitation in Rheumatology, Diakonhjemmet Hospital, Oslo, Norway
Background/Purpose: Osteoarthritis (OA) is a major cause of musculoskeletal pain and disability, and is commonly reported to impair health-related quality of life (HRQoL). We aimed…
Abstract Number: 2173 • 2015 ACR/ARHP Annual Meeting
Impact of Smoking on Patient-Reported Disease Status and Symptoms Among Women with Lupus
Patricia P. Katz¹, Eliza Chakravarty², Robert S. Katz³ and Kaleb Michaud⁴, ¹Medicine/Rheumatology, University of California San Francisco, San Francisco, CA, ²Arthritis and Clinical Immunology, Oklahoma Medical Research Foundation, Oklahoma City, OK, ³Rush University Medical Center, Chicago, IL, ⁴Internal Medicine, University of Nebraska Medical Center, Omaha, NE
Background/Purpose: Smoking appears to be associated both with an increased risk of rheumatoid arthritis and with more severe symptoms. The impact of smoking on patient-reported…
Abstract Number: 2174 • 2015 ACR/ARHP Annual Meeting
Neutrophils in Primary Antiphospholipid Syndrome Are Characterized By a Prominent Activated Phenotype and Uniquely Remodeled Chromatin Architecture
Patrick Coit, Srilakshmi Yalavarthi, Jason S. Knight and Amr H. Sawalha, Division of Rheumatology, University of Michigan, Ann Arbor, MI
Background/Purpose: Antiphospholipid syndrome (APS) is a systemic autoimmune disease characterized by recurrent thrombotic events, pregnancy complications, and the presence of antiphospholipid antibodies. The pathogenesis of…

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