Abstracts Archive - Page 1833 of 2607 - ACR Meeting Abstracts

Abstract Number: 2688 • 2015 ACR/ARHP Annual Meeting
Socioeconomic Status, Ethnicity/Race, and Autoantibody Status in Rheumatoid Arthritis
Mercedes Quinones¹, Sharon Dowell¹, Gail S. Kerr², Christopher Swearingen³, Yusuf Yazici⁴, Luis Espinoza⁵, Ignacio Garcia-Valladares⁶, Edward L. Treadwell⁷, Theresa Lawrence Ford⁸, Yvonne Scherrer⁹, Angelia Mosley-WIlliams¹⁰, Rodolfo Perez Alamino¹¹, Akgun Ince¹², John Amatruda¹³ and Jorge Flautero Arcos¹⁴, ¹Howard University Hospital, Washington, DC, ²Washington DC VAMC, Georgetown University Hospital, Howard University Hospital, Washington, DC, ³Pediatrics & Biostatistics, University of Arkansas, Little Rock, AR, ⁴Department of Medicine, Division of Rheumatology, New York University School of Medicine, New York, NY, ⁵Medicine-Section of Rheumatology, LSU Medical Center, New Orleans, LA, ⁶Immunology & Rheumatology, Hospital General de Occidente, Zapopan, Jalisco, Mexico, ⁷Dept Medicine Div of Rheum, E Carolina Univ Sch of Med, Greenville, NC, ⁸North Georgia Rheumatology Group, PC, Lawrenceville, GA, ⁹Center for Rheumatology & Immunology Arthritis, Fort Lauderdale, FL, ¹⁰John Dingell VAMC, Detroit, MI, ¹¹Rheumatology, Lousiana State University and LSU Medical Center, New Orleans, LA, ¹²Arthitis Consultants Inc, St. Louis University, St. Louis, MO, ¹³Rheumatology, Howard University, Washington, DC, ¹⁴Rheumatology, Howard University Hospital, Washington, DC
Background/Purpose: Ethnic disparities in outcomes of RA patients have been attributed to delayed presentation to specialty care and access to DMARDs, greater disease burden, and…
Abstract Number: 2689 • 2015 ACR/ARHP Annual Meeting
Discrepancies Between Patients and Physicians in Their Perceptions of Rheumatoid Arthritis Disease Activity Are Multifactorial in Early Rheumatoid Arthritis
Cécile Gaujoux-Viala¹, Nathalie Rincheval², Laure Gossec³, Francis Guillemin⁴, Maxime Dougados⁵, Jean-Pierre Daures⁶ and BG Combe⁷, ¹Nîmes University Hospital, Rheumatology Department; EA 2415, Montpellier University, Nîmes, France, ²Biostatistic, EA 2415, Epidemiology unit, Montpellier, France, ³Rheumatology, Pitié Salpetriere Hospital, Paris, France, ⁴University of Lorraine, Nancy, France, ⁵Paris Descartes University, Rheumatology Department, Cochin Hospital, AP-HP. INSERM (U1153): Clinical Epidemiology and Biostatistics, PRES Sorbonne Paris-Cité, Paris, France, ⁶Biostatistic, EA 2415 Epidemiology unit, Montpellier, France, ⁷Lapeyronie, Montpellier, France
Background/Purpose: Patients and physicians often differ in their perceptions of rheumatoid arthritis (RA) disease activity, as quantified by the patient's global assessment (PGA) and by…
Abstract Number: 2690 • 2015 ACR/ARHP Annual Meeting
The Effects of Disease of the Joints on Modified Health Assessment Questionnaire Scores in Rheumatoid Arthritis Patients: A Retrospective Study Using the National Database of Rheumatic Diseases By Ir-Net in Japan
Kumiko Ono¹, Satoru Ohashi², Hiroyuki Oka³, Yuho Kadono⁴, Yasunori Omata⁵, Takumi Matsumoto⁶, Sakae Tanaka¹ and Shigeto Tohma⁷, ¹Orthopaedic Surgery and Spinal Surgery, The University of Tokyo Hospital, Tokyo, Japan, ²Department of Orhopaedic Surgery, Sagamihara Hospital, National Hospital Organization, Kanagawa, Japan, ³Department of Joint Disease Research, 22nd Century Medical & Research Center, faculty of medicine,the university of Tokyo, Tokyo, Japan, ⁴Department of Orthopaedic Surgery, The University of Tokyo Hospital, Tokyo, Japan, ⁵Department of Orthopaedic Surgery and Spine Surgery, The University of Tokyo Hospital, Tokyo, Japan, ⁶Department of orthopaedic Surgery, The University of Tokyo Hospital, Tokyo, Japan, ⁷Sagamihara Hospital, National Hospital Organization, Sagamihara, Japan
Background/Purpose: Few studies of which joints most affect physical function in rheumatoid arthritis (RA) patients have been conducted. The present study investigated the effect of…
Abstract Number: 2691 • 2015 ACR/ARHP Annual Meeting
Musculoskeletal Ultrasound in Multi-Center Rheumatoid Arthritis Clinical Trials: Methodology for Optimizing Reliability of Acquisition and Real-Time Scoring
Veena K. Ranganath¹, Yossra Suliman^1,2, Jenny Brook³, David Elashoff³, Ami Ben-Artzi⁴, Cesar Olmos¹, Nabeel Borazan³, Thasia Woodworth¹ and Gurjit S. Kaeley⁵, ¹Medicine, Division of Rheumatology, David Geffen School of Medicine, Los Angeles, CA, ²Rheumatology and Rehabilitation department, Assiut university, Faculty of Medicine,, Assiut, Egypt, ³Medicine, David Geffen School of Medicine, Los Angeles, CA, ⁴David Geffen School of Medicine, Los Angeles, CA, ⁵University of Florida, Jacksonville, FL
Background/Purpose: Rheumatoid arthritis (RA) musculoskeletal ultrasound (MSUS) literature reports good reliability of scoring still images with training, but inconsistent reliability of scoring during acquisition, likely…
Abstract Number: 2692 • 2015 ACR/ARHP Annual Meeting
The Patients Evaluation of Pain and Disease Activity As Well As Improvement during One-Year Follow-up on Etanercept Treatment Is Highly Associated to Subjective Factors and Not to Objective Assessments Including Ultrasound
Hilde Berner Hammer¹ and Jon Lampa², ¹Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ²Dep of Medicine, Rheumatology unit, Karolinska Institute, Karolinska Institute, Stockholm, Sweden
Background/Purpose: Patient reported outcomes (PROs) are important for evaluation of treatment response in patients with rheumatoid arthritis (RA). Ultrasound (US) is a sensitive method for…
Abstract Number: 2693 • 2015 ACR/ARHP Annual Meeting
Comparing Eight Year Clinical and Radiographic Outcome in Two Cohorts of Patients with Rheumatoid Arthritis
Maria LE Andersson¹, Kristina Forslind² and Ingiäld Hafström³, ¹R&D Centre Spenshult,Halmstad, Halmstad, Sweden, ²Department of Medicine, Helsingborgs Lasarett, Section of Rheumatology, Helsingborg, Sweden, ³Rheumatology Dept, Karoliska Institute, Stockholm, Sweden
Background/Purpose: To compare patient and disease characteristics over the first 8 years of disease in a large inception cohort of early RA patients included 1992…
Abstract Number: 2694 • 2015 ACR/ARHP Annual Meeting
Variations in the Metabolome in Response to Disease Activity of Rheumatoid Arthritis
Zuzana Tatar¹, Carole Migne², Mélanie Petera³, Estelle Pujos Guillot⁴, Philippe Gaudin^5,6, T Lequerré⁷, Hubert Marotte⁸, Jacques Tebib⁹ and Martin Soubrier¹, ¹Rheumatology department CHU Clermont-Ferrand, Clermont-Ferrand, France, ²Metabolomic Plateform INRA, Theix-Clermont-Ferrand, France, ³Metabolomic Plateform, INRA, Theix -Clermont-Ferrand, France, ⁴Metabolomic Plateform, INRA, Theix-Clermont-Ferrand, France, ⁵Rheumatology, University Hospital, Grenoble, France, ⁶Rheumatology Department, CHU Hôpital Sud, Grenoble Teaching Hospital, Echirolles, France, ⁷Rheumatology Department and INSERM U 905, CHU Hôpitaux de Rouen, Rouen, France, ⁸INSERM 1059 / LBTO, Université de Lyon, Saint-Etienne; Rheumatology Department, Saint-Etienne, France, ⁹Rheumatology Department, Centre Hospitalier Lyon-Sud, Pierre-Bénite Lyon, France
Background/Purpose: Anti-TNF-alpha therapies are able to control rheumatoid arthritis (RA) disease activity and to limit structural damage. Nevertheless, no predictive factor of response to anti-TNF-alpha,…
Abstract Number: 2695 • 2015 ACR/ARHP Annual Meeting
Th17 Cell Related Cytokines and Microarray Expression Profiles in Patients with Early Rheumatoid Arthritis
Youngkyun Kim¹, Kijun Lee², Hae-Rim Kim³, Sang Heon Lee⁴, Ji Hyeon Ju⁵ and HO-YOUN KIM⁶, ¹1Convergent Research Consortium for Immunologic Disease, The Catholic University of Korea, Seoul, South Korea, ²The Catholic University of Korea, Seoul, South Korea, ³Konkuk University Medical Center, Seoul, South Korea, ⁴Konkuk University Hospital, Seoul, South Korea, ⁵Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea, ⁶Konkuk university hospital, Seoul, South Korea
Background/Purpose: The purpose of this study is to explore new biomarkers for early diagnosis of rheumatoid arthritis (RA). For better discrimination power, we especially investigated…
Abstract Number: 2696 • 2015 ACR/ARHP Annual Meeting
Geography and Association Between Patient Reported Outcomes and Disease Activity (DAS28) Components in Patients with Rheumatoid Arthritis, Among 17 Countries
Raluca Dumitru¹, Elizabeth M.A. Hensor¹, Ihsane Hmamouchi², Paul Emery³, Maxime Dougados⁴ and Maya H. Buch⁵, ¹University of Leeds, Leeds Institute of Molecular Medicine and LMBRU, Leeds, United Kingdom, ²El Ayachi Hospital, Rabat, Morocco, ³Academic Section of Musculoskeletal Disease, University of Leeds, Leeds Institute of Molecular Medicine and LMBRU, Leeds, United Kingdom, ⁴Service de Rhumatologie B, GHU Cochin, F-75014 France, PARIS, France, ⁵Division of Rheumatic and Musculoskeletal Disease, University of Leeds, Leeds Institute of Molecular Medicine and LMBRU, Leeds, United Kingdom
Background/Purpose: 28 joints-disease activity score (DAS28) is routinely used in clinical practice to assess disease activity in rheumatoid arthritis (RA). DAS28, particularly its subjective components…
Abstract Number: 2697 • 2015 ACR/ARHP Annual Meeting
Phenome-Wide Association Study of Rheumatoid Arthritis Subgroups Identifies Association Between Seronegative Disease and Fibromyalgia
Jayanth Doss¹, Huan Mo², Leslie J. Crofford¹ and Joshua C. Denny², ¹Rheumatology, Vanderbilt University School of Medicine, Nashville, TN, ²Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, TN
Background/Purpose: The differences between seronegative and seropositive rheumatoid arthritis (RA) have not been widely reported. We performed an electronic health record (EHR)-based phenome-wide association study…
Abstract Number: 2698 • 2015 ACR/ARHP Annual Meeting
Follicular Helper T Cells in Peripheral Blood of Patients with Rheumatoid Arthritis
Alicia Beatriz Costantino¹, Laura Onetti², Melina del Valle Cloquell³, Cristina del Valle Acosta¹, Eduardo Mussano², Isaac Ignacio Cadile², Cecilia María Rodriguez³, Stefania Santo¹ and Paola Virginia Ferrero¹, ¹Córdoba, Laboratorio de Inmunología. Hospital Nacional de Clínicas. Facultad de Ciencias Médicas. Universidad Nacional de Córdoba, Córdoba, Argentina, ²Córdoba, Servicio de Reumatología. Hospital Nacional de Clínicas. Facultad de Ciencias Médicas. Universidad Nacional de Córdoba, Córdoba, Argentina, ³Córdoba, Laboratorio de Oncohematología, Hospital Nacional de Clínicas, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Córdoba, Argentina
Background/Purpose: RA is an autoimmune, inflammatory and chronic disease which aetiology is unknown. It presents different autoantibodies such as RF and ACPA. A population of…
Abstract Number: 2699 • 2015 ACR/ARHP Annual Meeting
Muscle Inflammation Relates to Disease Activity and Disability but Not Insulin Resistance in Rheumatoid Arthritis
Ryan Jessee¹, Rachel Narowski², Monica Hubal³, Janet Huebner⁴, Virginia Kraus⁵, William Kraus⁶ and Kim Huffman^2,7, ¹Internal Medicine, Duke University Medical Center, Durham, NC, ²Duke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, ³Research and Education, George Washington University School of Medicine and Health Sciences, Washington, DC, ⁴Duke Molecular Physiology Institute,, Duke University Medical Center, Durham, NC, ⁵Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC, ⁶Division of Cardiology, Duke University Medical Center, Durham, NC, ⁷Durham Veterans Affairs Medical Center, Durham, NC
Background/Purpose: Rheumatoid arthritis (RA) is associated with increased cardiovascular disease, insulin resistance, and disability. Our objectives were to analyze levels of skeletal muscle inflammatory cytokines…
Abstract Number: 2700 • 2015 ACR/ARHP Annual Meeting
Trabecular Thinning in Metacarpophalangeal Joints of Anticitrullinated Peptide Antibody Positive Patients with Arthralgia
Kresten Krarup Keller¹, Jesper Skovhus Thomsen², Kristian Stengaard-Pedersen¹, Andreas Wiggers Nielsen¹, Berit Schiøtz-Christensen³, Lone Svendsen⁴, Merete Graakjær⁵, Peter Mosborg Pedersen⁶, Barbara Unger⁷, Bente Langdahl⁸ and Ellen-Margrethe Hauge¹, ¹Rheumatology, Aarhus University Hospital, Aarhus, Denmark, ²Aarhus University, Aarhus, Denmark, ³Spine Centre of Southern Denmark, Middelfart, Denmark, ⁴Private Practice in Rheumatology, Skanderborg, Denmark, ⁵Clinic of Rheumatology Aarhus, Aarhus, Denmark, ⁶Randers Hospital, Randers, Denmark, ⁷Horsens Hospital, Horsens, Denmark, ⁸Endocrinology, Aarhus University Hospital, Aarhus, Denmark
Background/Purpose: Rheumatoid arthritis (RA) is characterized by synovitis leading to bone erosions and joint destruction, but little is known about bone structure in the joints…
Abstract Number: 2701 • 2015 ACR/ARHP Annual Meeting
An Expansion of Rare Lineage Intestinal Microbes Characterize Rheumatoid Arthritis
Jun Chen¹, John M. Davis III², Eric L. Matteson³ and Veena Taneja⁴, ¹Health Sciences Research, Mayo Clinic, Rochesert, MN, ²Division of Rheumatology, Mayo Clinic, Rochester, MN, ³Division of Rheumatology, Department of Internal Medicine and Department of Health Sciences Research, Mayo Clinic, Rochester, MN, ⁴Immunology, Mayo Clinic, Rochester, MN
Background/Purpose: The adaptive immune response in Rheumatoid arthritis (RA) is influenced by an interaction between host genetics and environment, particularly the host microbiome. To define…
Abstract Number: 2702 • 2015 ACR/ARHP Annual Meeting
Immunophenotyping of Rheumatoid Arthritis Reveals the Linkage Between HLA-DRB1 Genotype, CXCR4 Expressions on Memory CD4+ T Cells, and Disease Activity
Yasuo Nagafuchi¹, Hirofumi Shoda¹, Shuji Sumitomo¹, Shinichiro Nakachi¹, Rika Kato², Yumi Tsuchida², Haruka Tsuchiya², Keiichi Sakurai², Norio Hanata², Shoko Tateishi², Hiroko Kanda², Keishi Fujio¹ and Kazuhiko Yamamoto¹, ¹Department of Allergy and Rheumatology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan, ²Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
Background/Purpose: The HLA-DRB1 is the strongest genetic risk factor for rheumatoid arthritis (RA). Although this fact suggests a pivotal role for adaptive immunity in RA,…

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