Abstracts Archive - Page 1804 of 2425 - ACR Meeting Abstracts

Abstract Number: 1724 • 2015 ACR/ARHP Annual Meeting
Abdominal X-Rays Can Reliably Detect the Majority of CT Positive Sacroiliitis in an IBD Cohort
Jonathan Chan¹, Ismail Sari², Ahmed Omar², Mark S. Silverberg³, David Salonen⁴, Robert D Inman⁵ and Nigil Haroon², ¹Rheumatology, Spondylitis program, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, ²Rheumatology, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, ³Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital IBD Group,, Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Toronto, ON, Canada, ⁴Department of Medical Imaging, University Health Network, Toronto, ON, Canada, ⁵Immunlogy and Institute of Medical Science, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada
Background/Purpose: There is a well-documented association between inflammatory bowel disease (IBD) and ankylosing spondylitis (AS). The hallmark feature of AS is the presence of sacroiliitis…
Abstract Number: 1725 • 2015 ACR/ARHP Annual Meeting
Reliable Evaluation of Structural Lesions of the Sacroiliac Joints on MRI in Patients with Axial Spondyloarthritis That Is Comparable to Evaluation of Inflammation Despite Minimal Calibration
Rosaline van den Berg¹, Susanne Juhl Pedersen², Victoria Navarro-Compán³, Stephanie Wichuk⁴, Manouk de Hooge⁵, Robert G Lambert⁶, Désirée van der Heijde⁵ and Walter Maksymowych⁷, ¹Leiden University Medical Center, Leiden, Netherlands, ²Copenhagen Center for Arthritis Research, Glostrup Hospital, University of Copenhagen, Copenhagen, Denmark, ³Rheumatology, University Hospital La Paz, Madrid, Spain, ⁴Medicine, Medicine, University of Alberta, Edmonton, AB, Canada, ⁵Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁶Radiology, Radiology, University of Alberta, Edmonton, AB, Canada, ⁷Medicine/Rheumatic Dis Unit, Medicine, University of Alberta, Edmonton, AB, Canada
Background/Purpose: There is growing recognition of the importance of structural lesions of the sacroiliac joints (SIJ) on MRI to the diagnostic evaluation of axial spondyloarthritis…
Abstract Number: 1726 • 2015 ACR/ARHP Annual Meeting
Reliability of Radiographic Assessment of Psoriatic Arthritis Mutilans
Dennis Wong¹, Ker-Ai Lee², Richard J. Cook³, Dafna Gladman⁴, Lihi Eder⁴ and Vinod Chandran⁴, ¹University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²Department of Statistics and Actuarial Science, University of Waterloo, Waterloo, ON, Canada, ³Statistics and Actuarial Science, University of Waterloo, Waterloo, ON, Canada, ⁴Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose: Psoriatic arthritis mutilans (PsAM) is the most severe form of Psoriatic arthritis (PsA). Research on PsAM has been hampered by the lack of an…
Abstract Number: 1727 • 2015 ACR/ARHP Annual Meeting
MRI Vertebral Corner Inflammation Followed By Fat Deposition Is the Strongest Contributor to the Development of New Bone at the Same Vertebral Corner: A Multi-Level Longitudinal Analysis in Patients with Ankylosing Spondylitis
Pedro Machado¹, Xenofon Baraliakos², Désirée van der Heijde³, Juergen Braun² and Robert Landewé⁴, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Rheumazentrum Ruhrgebiet, Herne, Germany, ³Dept. of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁴Division of Clinical Immunology and Rheumatology, Academic Medical Center / University of Amsterdam, Amsterdam, Netherlands
Background/Purpose: Syndesmophyte formation in ankylosing spondylitis (AS) is still insufficiently understood. Previous studies have suggested an association between MRI vertebral corner inflammation (VCI) and vertebral…
Abstract Number: 1728 • 2015 ACR/ARHP Annual Meeting
Diffusion Weighted Imaging Is a Sensitive and Specific MRI Protocol for the Diagnosis and Assessment of Disease Severity in Ankylosing Spondylitis
Linda A. Bradbury¹, Kelly A. Hollis², Benoit Gautier², Sateesh Shankaranarayana³, Philip Robinson⁴, Nivene Saad³, Kim-Anh Lê Cao² and Matthew A. Brown¹, ¹The University of Queensland Diamantina Institute, Brisbane, Australia, ²University of Queensland Diamantina Institute, Brisbane, Australia, ³Princess Alexandra Hospital, Brisbane, Australia, ⁴Human Genetics Group, University of Queensland Diamantina Insititute, Brisbane, Australia
Background/Purpose: Diffusion weighted imaging (DWI) is an MRI protocol which assesses the random Brownian motion of water molecules in the tissue imaged; this motion is…
Abstract Number: 1729 • 2015 ACR/ARHP Annual Meeting
Predictors and Clinical Factors Associated with Change in Spinal Inflammation Assessed on MRI over 2 Years: Data from Tasmanian Ankylosing Spondylitis Study
Hussain Ijaz Khan¹, Louisa Chou², Patricia Lewis³, Anitra Wilson³, Janet Millner⁴ and Jane Zochling³, ¹Musculoskeletal Unit, Menzies Institute of Medical Research, Hobart, Australia, ²Menzies Institute of Medical Research, University of Tasmania, Hobart, 7000, Australia, ³Menzies Institute of Medical Research, Hobart, Australia, ⁴Physiotherapy, Royal Hobart Hospital, Hobart, Australia
Background/Purpose: Ankylosing Spondylitis (AS) is debilitating disease affecting the axial skeleton which is often difficult to diagnose in early stages. Magnetic Resonance Imaging (MRI) is…
Abstract Number: 1730 • 2015 ACR/ARHP Annual Meeting
Good Control of Inflammation Counterbalances a Negative Impact of Radiographic Spinal Progression on Functional Status and Spinal Mobility in Patients with Ankylosing Spondylitis Treated with TNF Inhibitors
Denis Poddubnyy¹, Aleksandra Fedorova¹, Joachim Listing², Hildrun Haibel¹, Xenofon Baraliakos³, Jürgen Braun³ and Joachim Sieper¹, ¹Charité Universitätsmedizin Berlin, Berlin, Germany, ²German Rheumatism Research Centre, Berlin, Germany, ³Rheumazentrum Ruhrgebiet, Herne, Germany
Background/Purpose: Impaired function and spinal mobility in patients with ankylosing spondylitis (AS) can be caused by both spinal inflammation and new bone formation. Anti-TNF therapy…
Abstract Number: 1731 • 2015 ACR/ARHP Annual Meeting
Radiographic Damage of Facet Joints and Vertebral Bodies in the Cervical Spine in Patients with Ankylosing Spondylitis Treated with TNF Inhibitors
Fiona Maas¹, Suzanne Arends¹, Elisabeth Brouwer¹, Eveline van der Veer², Hendrika Bootsma¹, Rizwana Chaudhry¹, Monique Efde³, Freke Wink³ and Anneke Spoorenberg¹, ¹Rheumatology and Clinical Immunology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands, ²Laboratory Medicine, University Medical Center Groningen, University of Groningen, Groningen, Netherlands, ³Rheumatology, Medical Center Leeuwarden, Leeuwarden, Netherlands
Background/Purpose: In ankylosing spondylitis (AS), syndesmophyte formation and ankylosis of the vertebral bodies are characteristic radiographic changes that are evaluated during follow-up. However, the facet…
Abstract Number: 1732 • 2015 ACR/ARHP Annual Meeting
Slow Spinal Radiographic Progression in Patients with Ankylosing Spondylitis Treated with TNF Inhibitors
Fiona Maas¹, Suzanne Arends¹, Ivette Essers², Elisabeth Brouwer¹, Eveline van der Veer³, Freke Wink⁴, Monique Efde⁴, Hendrika Bootsma¹ and Anneke Spoorenberg¹, ¹Rheumatology and Clinical Immunology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands, ²Rheumatology, Maastricht University Medical Center, Maastricht, Netherlands, ³Laboratory Medicine, University Medical Center Groningen, University of Groningen, Groningen, Netherlands, ⁴Rheumatology, Medical Center Leeuwarden, Leeuwarden, Netherlands
Background/Purpose: Assessing radiographic progression in ankylosing spondylitis (AS) is challenging. The results regarding the effect of tumor necrosis factor-alpha (TNF-α) blocking therapy on spinal radiographic…
Abstract Number: 1733 • 2015 ACR/ARHP Annual Meeting
A Close Correlation Between Radiologic Progression Severity and Trabecular Bone Loss in Male Patients with Ankylosing Spondylitis
Ki-Jo Kim^1,2, In-Woon Baek³, Chong-Hyeun Yoon^4,5, Wan-Uk Kim⁶ and Chul-Soo Cho³, ¹Internal Medicine, St. Vincent’s Hospital, The Catholic University of Korea, Suwon, South Korea, ²St. Mary's Hospital, Seoul, South Korea, ³Internal Medicine, Yeouido St. Mary's Hospital, The Catholic University of Korea, Seoul, South Korea, ⁴Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea, ⁵Internal Medicine, Uijeongbu St. Mary's Hospital, The Catholic University of Korea, Uijeongbu, South Korea, ⁶Internal Medicine, Seoul St. Mary’s Hospital, The Catholic University of Korea, Seoul, South Korea
Background/Purpose: Ankylosing spondylitis (AS) is a chronic, progressive disease characterized by inflammation of entheses. Inflammation is associated with cortical new bone formation leading to progressive…
Abstract Number: 1734 • 2015 ACR/ARHP Annual Meeting
Computer Aided Syndesmophyte Measurement on Spinal Radiographs in Axial Spondyloarthritis Patients
F. de Bruin¹, Rosaline van den Berg¹, M. Reijnierse², D. van der Heijde^3,4 and B.C. Stoel², ¹Leiden University Medical Center, Leiden, Netherlands, ²Radiology, Leiden University Medical Center, Leiden, Netherlands, ³Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁴Rheumatology, Diakonhjemmet Hospital, Oslo, Norway
Background/Purpose: Quantifying syndesmophyte (Synd) length and angle in axial spondyloarthritis (axSpA) patients (pts) can be a helpful tool in monitoring disease progression. Objective was to…
Abstract Number: 1735 • 2015 ACR/ARHP Annual Meeting
Imaging and Clinical Factors Associated with Subchondral Sacroiliac Fatty Marrow in Axial Spondyloarthritis
Kavi Devulapalli¹, Xenofon Baraliakos², Daria Motamedi¹ and Lianne S. Gensler³, ¹Radiology, UCSF, SAN FRANCISCO, CA, ²Rheumazentrum Ruhrgebiet, Herne, Germany, ³Medicine/Rheumatology, University of California, San Francisco, San Francisco, CA
Background/Purpose: Magnetic resonance imaging (MR) plays an important role in the evaluation of inflammatory and structural changes in axial spondyloarthritis (axSpA) patients. Prior research suggests…
Abstract Number: 1736 • 2015 ACR/ARHP Annual Meeting
Is There Evidence to Support Replacing Conventional AP Pelvis Radiographs with Dedicated Sacroiliac Joint Views for the Diagnosis of Sacroiliitis?
Ahmed Omar¹, Ismail Sari¹, Mohamed Bedaiwi¹, Nigil Haroon¹ and Robert D Inman², ¹Rheumatology, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada, ²Immunlogy and Institute of Medical Science, Toronto Western Hospital, University of Toronto, Toronto, ON, Canada
Background/Purpose: Despite the development of advanced imaging modalities such as MRI and CT, conventional radiography remains the cornerstone for the diagnosis and classification of Ankylosing…
Abstract Number: 1737 • 2015 ACR/ARHP Annual Meeting
Increased Osteoclast Precursors with an Elevated DC-STAMP Expression May Identify Psoriasis Patients at Risk for Psoriatic Arthritis
Yahui Grace Chiu¹, Sutha Shanmugarajah², Dongge Li³, Megan Freiburger⁴, Sharon Moorehead⁵, Dafna Gladman⁶ and Christopher T. Ritchlin⁷, ¹Allergy, Immunology, and Rheumatology, University of Rochester, Rochester, NY, ²Toronto Western Hospital, Toronto, ON, Canada, ³Allergy, Immunology and Rheumatology, University of Rochester, Rochester, NY, ⁴Biology, University of Rochester, Rochester, NY, ⁵Allergy, Immunology & Rheumatology, University of Rochester, Rochester, NY, ⁶Allergy, Immunology & Rheumatology, Toronto Western Hospital, Toronto, ON, Canada, ⁷Allergy, Immunology and Rheumatololgy Division, University of Rochester Medical Center, Rochester, NY
Background/Purpose: Approximately 25% of psoriasis (Ps) patients develop into psoriatic arthritis (PsA) within 10 years. This Ps-to-PsA transition paradigm provides a unique opportunity to recognize…
Abstract Number: 1738 • 2015 ACR/ARHP Annual Meeting
Assessing the Validity of the Multi-Biomarker Disease Activity Assay in Patients with Psoriatic Arthritis
Tristan Boyd¹, Doquyen H. Huynh¹, P. Scott Eastman², Ferhan Qureshi³, Eric H. Sasso⁴, Rebecca J. Bolce⁴, Joshua Hillman⁵, David L. Boyle⁶ and Arthur Kavanaugh⁷, ¹Rheumatology, University of California San Diego, La Jolla, CA, ²Crescendo Bioscience, South San Francisco, CA, ³Crescendo Bioscience, Inc., South San Francisco, CA, ⁴Crescendo Bioscience Inc., South San Francisco, CA, ⁵Div of Rheum, UCSD School of Medicine, La Jolla, CA, ⁶Division of Rheumatology, Allergy and Immunology, University of California, San Diego, La Jolla, CA, ⁷University of California, San Diego School of Medicine, LaJolla, CA
Background/Purpose: Considerable heterogeneity across clinical domains of psoriatic arthritis (PsA) can make assessment of disease activity challenging. As a result, there has been interest in…

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