ACR Meeting Abstracts

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  • Abstract Number: 1559 • 2015 ACR/ARHP Annual Meeting

    Clinical Characteristics and Medication Use Among Arab Patients with Rheumatoid Arthritis in Some Arab States

    Karim Bayoumy1, Soha Roger Dargham1, Wessam Elhaq1, Samar Al Emadi2, Mohammed Hammoudeh2, Basel Masri3, Hussein Halabi4, Humeira Badsha5, Imad Uthman6, Salah Mahdy2, Robert Plenge7, Richa Saxena7, Marianthi Kapiri1 and Thurayya Arayssi8, 1Weill Cornell Medical College in Qatar, Doha, Qatar, 2Medicine, Hamad Medical Corporation, Doha, Qatar, 3Jordan Hospital, Amman, Jordan, 4Medicine, King Faisal Specialist Hospital and research center, Jeddah, Saudi Arabia, 5Al Biraa Arthritis and Bone Clinic, Dubai, United Arab Emirates, 6Internal Medicine, American University of Beirut, Beirut, Lebanon, 7The Broad Institute of MIT and Harvard, Program of Medical and Population Genetics, Cambridge, MA, 8Internal Medicine, Weill Cornell Medical College in Qatar, Doha, Qatar

    Background/Purpose: Data on the clinical and genetic characteristics of Arab patients with Rheumatoid Arthritis (RA) is limited. Our aim is to report on the clinical…
  • Abstract Number: 1560 • 2015 ACR/ARHP Annual Meeting

    The Effect of Anti Estrogen Therapy (AET) on Rheumatoid Arthritis

    Bassam Alhaddad1, Amrita Kaur Bath2, Bassem Zraik3, Mohamed Alalwani4 and Stanley P Ballou1, 1Rheumatology, Case Western Reserve University, MetroHealth Medical Center, Cleveland, OH, 2Internal medicine, Fairview Hospital- Cleveland Cinic, Cleveland, OH, 3Internal Medicine, Fairview Hospital- Cleveland Clinic, cleveland, OH, 4Hospital Medicine, Cleveland Clinic, Cleveland, OH

    Background/Purpose: The well-known positive effect of pregnancy on improving Rheumatoid Arthritis (RA) disease activity suggests that hormonal changes may play a role in disease pathogenesis…
  • Abstract Number: 1561 • 2015 ACR/ARHP Annual Meeting

    The Effect of TNF Blockers on Bone Mineral Density in Rheumatoid Arthritis Patients Receiving Bisphosphonate

    Doo-Ho Lim1, Seokchan Hong2, Soo Min Ahn2, Byeongzu Ghang3, Wook Jang Seo4, Yong-Gil Kim1, Chang-Keun Lee1 and Bin Yoo1, 1Division of Rheumatology, Department of Internal Medicine, Department of Rheumatology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea, 2Division of Rheumatology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea, 3Division of Rheumatology, Department of Internal Medicine, Univerisy of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea, 4Internal Medicine, Seoul Veterans Hospital, Seoul, South Korea

    Background/Purpose: Osteoporosis is more frequently observed in patients with rheumatoid arthritis (RA) than in general population. Bisphosphonate (BP), which suppresses bone resorption by inhibiting osteoclast…
  • Abstract Number: 1562 • 2015 ACR/ARHP Annual Meeting

    Clinical Correlates, Outcomes and Predictors of Episcleritis and Scleritis Associated with Rheumatoid Arthritis

    Cristian Caimmi1, Wendy M. Smith2, Cynthia S. Crowson3, Eric L. Matteson4 and Ashima Makol5, 1Unit of Rheumatology, Department of Medicine,, University of Verona, Verona, Italy, 2Department of Ophthalmology, Mayo Clinic, Rochester, MN, 3Division of Rheumatology and Department of Health Sciences Research, Mayo Clinic, Rochester, MN, 4Division of Rheumatology, Department of Internal Medicine and Department of Health Sciences Research, Mayo Clinic, Rochester, MN, 5Division of Rheumatology, Department of Internal Medicine, Mayo Clinic, Rochester, MN

    Background/Purpose: Inflammatory ocular disease (IOD) has traditionally been regarded as a severe extra-articular manifestation of rheumatoid arthritis (RA) with high mortality. This study aims to…
  • Abstract Number: 1563 • 2015 ACR/ARHP Annual Meeting

    Dyslipidemia and Hyperglycemia, Two Cardiometabolic Parameters, Independently Predict Poor Outcome in Early Rheumatoid Arthritis: Results from Espoir Cohort

    Claire I. Daien1, Jeremie Sellam2, Nathalie Rincheval3, Bruno Fautrel4, Alain Saraux5, Francis Berenbaum6, Jacques Morel1, Jean-Pierre Daures7 and Bernard Combe8, 1Department of rheumatology, Lapeyronie Hospital and Montpellier University, Montpellier, France, 2Department of Rheumatology, Assistance Publique – Hôpitaux de Paris, Saint-Antoine Hospital, Paris, France, 3Biostatistic, EA 2415, Epidemiology unit, Montpellier, France, 4Rheumatology, AP-HP Pitié-Salpêtrière Hospital / Pierre and Marie Curie University Paris 6 GRC-08 (EEMOIS), Paris, France, 5Rheumatology Department, CHU de la Cavale Blanche, Brest Cedex, France, 6Rheumatology and Paris VI University, Saint-Antoine Hospital, Paris, France, 7Biostatistic, EA 2415 Epidemiology unit, Montpellier, France, 8Rheumatology, Hopital Lapeyronie, Montpellier, France

    Background/Purpose: Previous studies showed that obesity in patients with rheumatoid arthritis (RA) is associated with higher disease activity. Beyond obesity, cardiometabolic disturbances may impact the…
  • Abstract Number: 1564 • 2015 ACR/ARHP Annual Meeting

    Initiation of Disease Modifying Therapies and Subsequent Weight Change in Rheumatoid Arthritis

    Joshua Baker1, Brian Sauer2, Kaleb Michaud3, Grant W. Cannon4, Said Ibrahim5, Liron Caplan6, Lisa A. Davis6, Amy C. Cannella7 and Ted R. Mikuls8, 1Medicine/Rheumatology, University of Pennsylvania, Philadelphia, PA, 2IDEAS Center and Division of Epidemiology, HSR&D SLC VA Medical Center and University of Utah, Salt Lake City, UT, 3Rheumatology & Immunology, University of Nebraska Medical Center and National Data Base for Rheumatic Diseases, Omaha, NE, 4Internal Medicine, Veterans Affairs Salt Lake City Health Care System, Salt Lake City, UT, 5Medicine, University of Pennsylvania, Philadelphia, PA, 6Div of Rheumatology, Univ of CO Denver School of Med, Aurora, CO, 7Section of Rheumatology, University of Nebraska Med Ctr, Omaha, NE, 8University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Low body mass index (BMI) predicts adverse outcomes in rheumatoid arthritis (RA), in part due to weight loss among patients with severe disease and…
  • Abstract Number: 1565 • 2015 ACR/ARHP Annual Meeting

    High Disease Activity over Time and Persistent Inflammation Are Associated with Increased Risk of Cardiovascular Disease in Patients with Early Rheumatoid Arthritis

    Emil Rydell1,2, Christina Book1,2, Jan-Åke Nilsson1,2, Minna Willim1,2, Lennart T.H. Jacobsson1,3 and Carl Turesson1,4, 1Rheumatology, Department of Clinical Sciences, Malmö, Lund University, Malmö, Sweden, 2Department of Rheumatology, Skåne University Hospital, Malmö, Sweden, 3Department of Rheumatology and Inflammation Research, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden, 4Lund University, Rheumatology, Dept. of Clinical Sciences,, Malmö, Sweden

    Background/Purpose: Rheumatoid arthritis (RA) is associated with an increased rate of cardiovascular (CV) disease. Systemic inflammation has been implicated as a key factor behind CV…
  • Abstract Number: 1566 • 2015 ACR/ARHP Annual Meeting

    The Impact of Severe Extra-Articular Manifestations and Patient Reported Outcome Measures on Cardiovascular Disease in Rheumatoid Arthritis

    Lisa Theander1, Jan-Åke Nilsson1, Minna Willim1,2, Britt-Marie Nyhäll-Wåhlin1,3, Lennart T.H. Jacobsson1,4 and Carl Turesson1,5, 1Rheumatology, Department of Clinical Sciences, Malmö, Lund University, Malmö, Sweden, 2Department of Rheumatology, Skåne University Hospital, Malmö, Sweden, 3Department of Rheumatology, Falun Hospital, Falun, Sweden, 4Department of Rheumatology and Inflammation Research, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden, 5Lund University, Rheumatology, Dept. of Clinical Sciences,, Malmö, Sweden

    Background/Purpose: Rheumatoid arthritis (RA) is associated with increased risk of cardiovascular disease (CVD). Disease severity, including extra-articular rheumatoid arthritis (ExRA) manifestations, has previously been demonstrated…
  • Abstract Number: 1567 • 2015 ACR/ARHP Annual Meeting

    Occurrence of Serious Infection in Patients with Rheumatoid Arthritis Treated with Biologics and Denosumab Observed in a Clinical Setting

    Matthew Wong-Pack1, Rod Rodjanapiches1, Arthur Lau1,2,3, George Ioannidis1,3, Sally Wade4, Leslie Spangler4, Celia JF Lin4, Patrick Roy-Gayos1, William G Bensen1,3, Robert Bensen3 and Jonathan D Adachi1,3, 1McMaster University, Hamilton, ON, Canada, 2Division of Rheumatology, McMaster University, Hamilton, ON, Canada, 3St Joseph's Healthcare Hamilton, Hamilton, ON, Canada, 4Amgen Inc., Thousand Oaks, CA

    Background/Purpose: Previous studies combining immunosuppressive biologics have shown an increased risk of infections. Few studies have examined the risk of infection with concurrent use of…
  • Abstract Number: 1568 • 2015 ACR/ARHP Annual Meeting

    Cardiac Morphology and Function in Patients with Acute Coronary Syndrome Complicated with Rheumatoid Arthritis

    Li-Li Pan1 and Tian Wang2, 1Rheumatology and Immunology, Beijing Anzhen Hospital affiliated to Capital Medical University, Beijing, China, 21. Department of Rheumatology and Immunology,, Beijing An Zhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung, and Blood Vessel Diseases, Beijing, China

    Background/Purpose: Cardiovascular diseases are important contributors to the excess of overall morbidity and mortality in patients with rheumatoid arthritis (RA). The aim of this study…
  • Abstract Number: 1569 • 2015 ACR/ARHP Annual Meeting

    Rituximab Efficacy in the Treatment of Diffuse Interstitial Lung Disease Associated with Rheumatoid Arthritis

    Javier Narváez1, Milagros Ricse2, Juan José Alegre3, Gloria Albert Espi3, Carmen Gomez Vaquero4, Helena Borrell Paños2, Eulalia Armengol2, Joan Miquel Nolla2, Susana Herrera5 and Maria Molina6, 1Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, 2Department of Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, 3Rheumatology Department, Hospital Universitario Doctor Peset, Valencia, Spain, 4Department of Rheumatology, Hospital Universitario Bellvitge, Barcelona, Spain, 5Deparment of Pneumology, Hospital Universitario Dr Peset, Valencia, Spain, 6Department of Pneumology, Hospital Universitario de Bellvitge, Barcelona, Spain

    Background/Purpose: To investigate the efficacy and safety of rituximab (RTX) in the the management of progressive rheumatoid arthritis related interstitial lung disease (RA-ILD). Methods: An…
  • Abstract Number: 1570 • 2015 ACR/ARHP Annual Meeting

    End Stage Renal Disease (ESRD) in Patients with Rheumatoid Arthritis

    Sunita Paudyal1, Monique Bethel2, Frances Yang1, Alyce Oliver1, Michael Skelton1, Christopher Rice1, Brian Le3, Shilpa Brown1, Stanley Nahman1 and Laura Carbone4, 1Georgia Regents University, Augusta, GA, 2Internal Medicine, Georgia Regents University, Augusta, GA, 3Medicine, Georgia Regents University, Augusta, GA, 4Rheumatology, Georgia Regents University, Augusta, GA

    Background/Purpose: Substantial progress has been made in the treatment of rheumatoid arthritis (RA) and life expectancy has increased. As the population of patients with RA…
  • Abstract Number: 1571 • 2015 ACR/ARHP Annual Meeting

    How Substantive Is Heart Rate Variability As a Predictor of Anti-TNF Treatment Outcome for Inflammatory Arthritis?

    Andrew Holman1 and Edmund Ng2, 1Inmedix, Normandy Park, WA, 2Statistical Thinking, Seattle, WA

    Background/Purpose: As rheumatologists search for new targets to improve immunosuppressive outcomes, the autonomic nervous system (ANS) as a co-factor in autoimmune disease expression has gained…
  • Abstract Number: 1572 • 2015 ACR/ARHP Annual Meeting

    Plasma Apolipoprotein B48 Levels in Patients with Rheumatoid Arthritis: Evaluating Novel Cardiovascular Risk Factors

    Deborah van Breukelen-van der Stoep1, Derkjen van Zeben1, Marijke de Vries2, Boudewijn Klop2, Noelle van der Meulen2, Gert Jan van de Geijn3, Hans Janssen3, Pedro Valdivielso4, José Rioja4, José Ramirez-Bollero4, Mieke Hazes5, Erwin Birnie6,7 and Manuel Castro Cabezas8, 1Department of Rheumatology, Sint Franciscus Gasthuis, Rotterdam, Netherlands, 2Department of Internal Medicine, Sint Franciscus Gasthuis, Rotterdam, Netherlands, 3Department of Clinical Chemistry, Sint Franciscus Gasthuis, Rotterdam, Netherlands, 4Department of Internal Medicine and Dermatology, Hospital Virgen de la Victoria, Malaga, Spain, 5Department of Rheumatology, Erasmus Medical Centre Rotterdam, Rotterdam, Netherlands, 6Statistics and Education, Sint Franciscus Gasthuis, Rotterdam, Netherlands, 7Insitute of Health Policy and Management, Erasmus University, Rotterdam, Netherlands, 8Department of Internal Medicine, Sint Francicscus Gasthuis, Rotterdam, Netherlands

    Background/Purpose: Chylomicrons, with apolipoprotein (apo) B48 as a structural protein, induce leukocyte and complement activation and contribute to atherosclerosis. ApoB48 is higher in conditions associated…
  • Abstract Number: 1573 • 2015 ACR/ARHP Annual Meeting

    Plasma Pentraxin 3 Concentration Is Associated with Progression of Radiographic Joint Damage but Not with Carotid Atherosclerosis in Female Patients with Rheumatoid Arthritis: Results from a 3-Year Prospective Study

    Yu Asanuma1, Yuki Shimada2, Yoshimi Aizaki1, Kazuhiro Yokota1, Noritsune Kouzu3, Yoshitake Takebayashi4, Hisashi Noma4, Shinichi Kawai5 and Toshihide Mimura2, 1Department of Rheumatology and Applied Immunology, Faculty of Medicine, Saitama Medical University, Saitama, Japan, 2Saitama Medical University, Saitama, Japan, 3Kouzu Orthopaedic Clinic, Chiba, Japan, 4The Institute of Statistical Mathematics, Tokyo, Japan, 5Div of Rheum/dept of Int Med, Toho Uni Sch of Med, Tokyo, Japan

    Background/Purpose: Pentraxin 3 (PTX3) plays an important role in inflammation, immunity, and atherosclerosis. Plasma PTX3 level is recognized as a marker that responds to local…
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