Abstracts Archive - Page 1784 of 2425 - ACR Meeting Abstracts

Abstract Number: 1423 • 2015 ACR/ARHP Annual Meeting
Racial Disparities in Pain and Function after Total Knee Arthroplasty in the United States: A Systematic Literature Review
Susan M. Goodman¹, Kelly McHugh¹, Michael Parks², Mark P. Figgie³, Yuo-Yu Lee⁴, Kara Fields⁵, Rie Smethurst⁶ and Anne R. Bass¹, ¹Rheumatology, Hospital for Special Surgery, New York, NY, ²Orthopedics, Hospital for Special Surgery, New York, NY, ³Orthopaedics, Hospital for Special Surgery, New York, NY, ⁴Epidemiology and Biostatistics, Hospital for Special Surgery, New York, NY, ⁵Medicine/Rheumatology, Hospital for Special Surgery, New York, NY, ⁶Education - Academic Training, Hospital for Special Surgery, New York, NY
Background/Purpose: Blacks in the United States (US) are less likely to undergo total knee arthroplasty (TKA) than whites, in part because they expect to benefit…
Abstract Number: 1424 • 2015 ACR/ARHP Annual Meeting
Barriers to Primary Care Clinician Adherence to Clinical Guidelines for the Management of Low Back Pain: A Systematic Review and Meta-Synthesis of Qualitative Studies
Susan Slade¹, Peter Kent², Shilpa Patel³, Tracey Bucknall⁴ and Rachelle Buchbinder¹, ¹Monash Department of Clinical Epidemiology, Cabrini Institute and Monash University, Melbourne, Australia, ²Department of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark, ³Warwick Clinical Trials Unit, The University of Warwick, Warwick, United Kingdom, ⁴School of Nursing & Midwifery, Deakin University and Alfred Health, Melbourne, Australia
Background/Purpose: Low back pain is the highest ranked condition contributing to years lived with disability according to the most recent Global Burden of Disease study…
Abstract Number: 1425 • 2015 ACR/ARHP Annual Meeting
Current Tobacco Use and the Rates of Complications after Total Hip Arthroplasty
Jasvinder A. Singh, University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: The risk of postoperative complication with tobacco use disorder and complication after total hip arthroplasty (THA) are not known. Our objective was to compare…
Abstract Number: 1426 • 2015 ACR/ARHP Annual Meeting
The Effect of Anti-Interleukin-6 Receptor Antibody in Ovariectomized Mice
Sho Kato¹, Hiroki Wakabayashi², Taro Nakagawa³, Yohei Naito³, Takahiro Iino⁴ and Akihiro Sudo⁵, ¹Department of Orthopaedic Surgery, Mie University Graduate School of Medicine, Tsu City, Japan, ²Orthopaedic Surgery, Mie University Graduate School of Medicine, Tsu City, Japan, ³Department of Orthopaedic Surgery, Mie University Graduate School of Medicine, Tsu City, Mie, Japan, ⁴Mie University Graduate School of Medicine, Mie University Graduate School of Medicine, Tsu City, Mie, Japan, ⁵Orthopaedic surgery, Mie University Postgraduate School of Medicine, Tsu-city, Japan
Background/Purpose: Osteoporotic patients with no evidence of fractures sometimes experience vague low back pain. Bone pain associated with bone metastasis may also be related to…
Abstract Number: 1427 • 2015 ACR/ARHP Annual Meeting
Analgesic Effects of the Novel Alpha-2-Delta Ligand Mirogabalin (DS-5565) in Experimental Animal Models of Fibromyalgia
Yuki Domon¹, Naohisa Arakawa¹, Shun-ichi Yasuda², Kensuke Saeki², Mayumi Kano², Masami Kato² and Yutaka Kitano¹, ¹Biological Research Laboratories, Daiichi Sankyo Co., Ltd., Tokyo, Japan, ²Hashima Laboratory, Nihon Bioresearch Inc., Gifu, Japan
Background/Purpose: Mirogabalin (DS-5565) is a novel ligand of the α2δ subunit of voltage-gated calcium channels. Mirogabalin possesses unique binding characteristics to α2δ subunits, and potent…
Abstract Number: 1428 • 2015 ACR/ARHP Annual Meeting
Subchondral Bone Structure and Pain Behaviors in Complete Freund’s Adjuvant (CFA) Monoarthritis in Mice Treated with Intra-Articular (IA) Neurotoxin
Hollis E. Krug^1,2, Joseph Bert³, Fakhar Abbass⁴, Christopher W. Dorman⁵, Sandra Frizelle⁵ and Maren L. Mahowald^1,2, ¹Medicine, Minneapolis VA Health Care System, Minneapolis, MN, ²Medicine, University of Minnesota, Minneapolis, MN, ³Internal Medicine, Division of Rheumatology, University of Minnesota, Minneapolis, MN, ⁴Minneapolis VA Health Care System, Minneapolis, MN, ⁵Research, Minneapolis VA Health Care System, Minneapolis, MN
Background/Purpose: Bone histomorphometry can define OA changes in rodents and in Antigen-Induced arthritis (AIA) in rats. We produced painful inflammatory monoarthritis in mouse knees with IA…
Abstract Number: 1429 • 2015 ACR/ARHP Annual Meeting
The Effect of Gabapentin and Cyclooxygenase Inhibitors on Evoked and Ongoing Pain-like Behavior in Two Arthritis Models in Mice
Katalin Sandor¹, HueJung Park², Johanna McQueen³, Sarah Woller³, Maripat Corr⁴, Camilla Svensson¹ and Tony Yaksh³, ¹Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden, ²College of Medicine, Department of Anesthesiology and Pain Medicine, The Catholic University of Korea, Seoul, South Korea, ³Anesthesiology, UCSD, La Jolla, CA, ⁴Division of Rheumatology, Allergy, and Immunology, UCSD, La Jolla, CA
Background/Purpose: Induction of K/BxN serum transfer arthritis and collagen antibody-induced arthritis (CAIA) leads to transient joint inflammation but persistent mechanical hypersensitivity lasting at least 2…
Abstract Number: 1430 • 2015 ACR/ARHP Annual Meeting
Peripheral HMGB1 Regulates Arthrtis-Associated Pain-like Behaviour
Nilesh Agalave¹, Teresa Fernandez Zafra², Peter Lundback³, Ulf Andersson⁴, Helena E. Harris³ and Camilla Svensson⁵, ¹Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden, ²Physiology and pharmacology, Karolinska Institutet, Stockholm, Sweden, ³Center for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden, ⁴Center for Molecular medicine, Karolinska Institutet, Stockholm, Sweden, ⁵Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
Background/Purpose: HMGB1 has received attention for its emerging roles in the extracellular environment acting as damage associated molecular pattern molecule. The redox state of HMGB1…
Abstract Number: 1431 • 2015 ACR/ARHP Annual Meeting
Age and Sex Impacts the Development of Hypersensitivity in the Murine Partial Medial Menisectomy Model of Osteoarthritis
Ada Delaney¹, Azar Barharpoor¹, Tianle Gao¹, Jie Su¹, NIlesh Agalave¹ and Camilla Svensson², ¹Dept. of Physiology & Pharmacology, Karolinska Institutet, Stockholm, Sweden, ²Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden
Background/Purpose: Osteoarthritis (OA) is the leading cause of chronic pain in European adults (37%; painineurope.com). Pain is the foremost symptom of OA, with both episodes…
Abstract Number: 1432 • 2015 ACR/ARHP Annual Meeting
Relationship Between Patient Reported Outcome Measures and Evoked Pain Measures in Knee Osteoarthritis
J. Ryan Scott¹, Steven E. Harte¹, David A. Williams^2,3, Daniel J. Clauw⁴ and Kristine Phillips⁵, ¹Department of Anesthesiology, University of Michigan, Ann Arbor, MI, ²Chronic Pain & Fatigue Rsch Ctr, Univ of MI Hlth System-Lobby M, Ann Arbor, MI, ³Anesthseiology, University of Michigan, Ann Arbor, MI, ⁴Anesthesiology, University of Michigan, Ann Arbor, MI, ⁵Internal Medicine, University of Michigan, Ann Arbor, MI
Background/Purpose: Quantitative sensory testing (QST) can be used to assess pain processing mechanisms, and theoretically identify a subset of chronic pain patients that has central…
Abstract Number: 1433 • 2015 ACR/ARHP Annual Meeting
Predicting Response to Osteoarthritis Treatment Based on Patient Reported Outcome Measures and Quantitative Sensory Testing
Kristine Phillips¹, David A. Williams², Arnold Gammaitoni³, J. Ryan Scott⁴, Steven E. Harte⁴, Susan L. Murphy⁵ and Daniel J. Clauw⁶, ¹Internal Medicine, University of Michigan, Ann Arbor, MI, ²Anesthseiology, University of Michigan, Ann Arbor, MI, ³Zogenix, Inc, San Diego, CA, ⁴Department of Anesthesiology, University of Michigan, Ann Arbor, MI, ⁵Phyiscal Medicine & Rehabilitation, University of Michigan, Ann Arbor, MI, ⁶Anesthesiology, University of Michigan, Ann Arbor, MI
Background/Purpose: Recent studies have suggested that a subset of individuals with arthritis have a component of sensitization to their pain. This subset of patients with…
Abstract Number: 1434 • 2015 ACR/ARHP Annual Meeting
Neuropathic Pain in Patients with Rheumatoid Arthritis: Relation with Clinical Variables
Ferda Kaygisiz¹, Pinar Borman² and Aynur Karagoz³, ¹Dept of Physical Medicine and Rehabilitation, Ankara Training and Research Hospital, Ankara, Turkey, ²Department of Physical Medicine and Rehabilitation, University of Hacettepe Faculty of Medicine, Ankara, Turkey, ³Dept of Physical Medicine and Rehabilitation, Ministry of Health, Ankara Training and Research Hospital, Ankara, Turkey
Background/Purpose: There are few studies in the literature indicating that neuropathic pain occurs in rheumatoid arthritis (RA). The aim of this cross sectional study was…
Abstract Number: 1435 • 2015 ACR/ARHP Annual Meeting
Central Pain Sensitization in Rheumatoid Arthritis – Role of ACPA?
Katarzyna Rogoz¹, Teresa Fernandez Zafra¹, Catia Cerqueira², Per Johan Jakobsson³, Katalin Sandor⁴, Erwan Le Maître⁵, Magnus LA. Andersson⁶, K. Lundberg⁷, Camilla Svensson⁴ and Jon Lampa⁸, ¹Physiology and pharmacology, Karolinska Institutet, Stockholm, Sweden, ²Rheumatology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, ³Department of Medicine, Unit of Rheumatology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden, ⁴Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden, ⁵Department of Medicine, Karolinska Institutet, Stockholm, Sweden, ⁶Dep of Neurology, Karolinska Institute, Stockholm, Sweden, ⁷Karolinska Institute, Stockholm, Sweden, ⁸Dep of Medicine, Rheumatology unit, Karolinska Institute, Karolinska Institute, Stockholm, Sweden
Background/Purpose: Chronic pain continues to be a significant problem for patients with rheumatoid arthritis (RA), even when the disease is medically controlled or in remission.…
Abstract Number: 1436 • 2015 ACR/ARHP Annual Meeting
Characterization of Patient Reported Pain Medication in Early Vs. Established Rheumatoid Arthritis
Apoorva Kelkar, Angela Cesta, Xiuying Li and Claire Bombardier, Toronto General Hospital Research Institute, University Health Network, Toronto, ON, Canada
Background/Purpose: Pain control in rheumatic diseases is complex and various pharmacotherapy approaches can be utilized for management of rheumatic pain. Currently, systematic clinical practice guidelines…
Abstract Number: 1437 • 2015 ACR/ARHP Annual Meeting
Prevalence of Pain, Its Impact and Management in a Population-Based Cohort of Patients with Rheumatoid Arthritis: Data from the Australian Rheumatology Association Database
Bethan Richards^1,2, Rachelle Buchbinder³, Marissa N. Lassere⁴ and Lyn March⁵, ¹Sydney Medical School, University of Sydney, Sydney, Australia, ²Royal Prince Alfred Hospital, Mulgrave, Vic, Australia, ³Monash Department of Clinical Epidemiology, Cabrini Institute and Monash University, Melbourne, Australia, ⁴Dept of Rheumatology, St George Hospital, Kogarah, Australia, ⁵Department of Rheumatology, Northern Clinical School, Institute of Bone and Joint Research, Kolling Institute, University of Sydney & Department of Rheumatology, Royal North Shore Hospital, St Leonards, Sydney, Australia
Background/Purpose: Despite advances in the treatments available for rheumatoid arthritis (RA), many patients continue to experience musculoskeletal pain. Untreated and under-treated pain are well known to increase…

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