Abstracts Archive - Page 1761 of 2607 - ACR Meeting Abstracts

Abstract Number: 2432 • 2016 ACR/ARHP Annual Meeting
Immune Abnormalities Leading to Exaggerated Production of IFN-Gamma (IFNγ) and the Therapeutic Response to an Anti-IFNγ Antibody in a Patient with NRLC4 Mediated Disease
Claudia Bracaglia¹, Giusi Prencipe², Manuela Pardeo¹, Geneviève Lapeyre³, Emiliano Marasco², Antonella Insalaco¹, Walter Ferlin³, Robert Nelson³, Cristina de Min³ and Fabrizio De Benedetti¹, ¹Division of Rheumatology, Ospedale Pediatrico Bambino Gesù IRCCS, Roma, Italy, Rome, Italy, ²Division of Rheumatology, Ospedale Pediatrico Bambino Gesù IRCCS, Rome, Italy, ³NovImmune S.A., Geneva, Switzerland
Background/Purpose: Animal and human data suggest that IFNγ plays a pathogenic role in HLH. A phase 2 trial with the anti-IFNγ monoclonal antibody NI-0501 in…
Abstract Number: 2433 • 2016 ACR/ARHP Annual Meeting
Trends in Use of Hydroxychloroquine during Pregnancy in SLE Patients from 2001 to 2012
Bonnie L. Bermas¹, Seoyoung Kim^2,3, Krista Huybrechts⁴, Sonia Hernandez-diaz⁵, Brian T. Bateman⁶ and Rishi J. Desai⁷, ¹Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ²Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ³Division of Pharmacoepidemiology and Pharmocoeconomics, Brigham and Women's Hospital, Boston, MA, ⁴Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women’s Hospital, Boston, MA, ⁵Harvard School of Public Health, Boston, MA, ⁶Division of Pharmacoepidemiology and Pharocoeconomics, Brigham and Women's Hospital, Boston, MA, ⁷PharmacoEpidemiology & PharmacoEconomics, Brigham & Women's Hospital, Boston, MA
Background/Purpose : Data suggest that hydroxychloroquine (HCQ) use during systemic lupus erythematosus (SLE) pregnancies improves outcomes. In the past decade, single-center studies report that a…
Abstract Number: 2435 • 2016 ACR/ARHP Annual Meeting
Counseling on Family Planning and Contraception, and Pregnancy Outcome in Women with Rheumatic Diseases: Analysis of 398 Patient-Reported Questionnaires from a Multicenter Italian Study
Francesca Dall'Ara¹, Maria Grazia Lazzaroni¹, Laura Andreoli¹, Marilia Rodrigues², Carolina Benigno³, Elena Bartoloni-Bocci⁴, Corrado Capochiaro⁵, Cecilia B. Chighizola⁶, Paola Conigliaro⁷, ADA Corrado⁸, Salvatore D'Angelo⁹, maria favaro¹⁰, Elena Generali¹¹, Maria Gerosa¹², M larosa¹³, Marianna Meroni¹⁴, Melissa Padovan¹⁵, Giulia Pazzola¹⁶, Susanna Peccatori¹⁷, Imma Prevete¹⁸, Véronique Ramoni¹⁹, G Sebastiani²⁰, Chiara Tani²¹, Marica Trevisani²², M Vadacca²³, Ester Vivaldelli²⁴, E Visalli²⁵, L Zuliani²⁶, A Afeltra²³, Elena Baldissera²⁷, Antonio Brucato²⁸, Francesco Paolo Cantore²⁹, Roberto Caporali³⁰, Maurizio Cutolo³¹, Andrea Doria³², Rosario Foti³³, Armando Gabrielli³⁴, Roberto Gerli³⁵, Marcello Govoni³⁶, Armin Maier²⁴, Nazzarena Malavolta³⁷, Pier Luigi Meroni³⁸, Giovanni Minisola¹⁸, Carlo Maurizio Montecucco³⁹, Marta Mosca⁴⁰, Ignazio Olivieri⁴¹, Giuseppe Paolazzi⁴², Roberto Perricone⁴³, N Romeo⁴⁴, Amelia Ruffatti⁴⁵, Maria Grazia Sabbadini⁵, Carlo Salvarani⁴⁶, Carlo Selmi⁴⁷, Luigi Sinigaglia⁴⁸ and Angela Tincani¹, ¹Rheumatology and Clinical Immunology, Spedali Civili and University of Brescia, Brescia, Italy, ²Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal, Coimbra, Portugal, ³University Federico II, Napoli, Italy, Napoli, Jamaica, ⁴Department of Medicine, Rheumatology Unit, University of Perugia, Perugia, Italy, ⁵Ospedale San Raffaele, Milano, Italy, milano, Italy, ⁶Department of Clinical Sciences and Community Health, University of Milan, IRCCS Istituto Auxologico Italiano, Milano, Italy, ⁷Policlinico and University of Tor Vergata, Roma, Italy, roma, Italy, ⁸Ospedali Riuniti of Foggia, Foggia, Italy, foggia, Italy, ⁹Rheumatology Department of Lucania, San Carlo Hospital of Potenza and Madonna delle Grazie Hospital of Matera, matera, Italy, ¹⁰Rheumatology Unit, University and Azienda Ospedaliera of Padova, Padova, Italy, padova, Italy, ¹¹Rheumatology and Clinical Immunology, Humanitas Research Hospital, Rozzano (MI), Italy, ¹²University of Milan, Istituto Ortopedico Gaetano Pini, Milano, Italy, ¹³University and Azienda Ospedaliera of Padova, Padova, Italy, padova, Italy, ¹⁴University of Genova-IRCCS San Martino Genova, Genova, Italy and ASST Papa Giovanni XXIII, Bergamo, Italy, genova, Italy, ¹⁵Department if Clinical and Experimental Medicine, University of Ferrara, Section of Rheumatology, Ferrara, Italy, ¹⁶Rheumatology Unit, Internal Medicine Department, Arcispedale Santa Maria Nuova - IRCCS, Reggio Emilia, Italy, ¹⁷Azienda Provinciale Servizi Sanitari, Trento, Italy, trento, Italy, ¹⁸Azienda Ospedaliera San Camillo, Roma, Italy, Roma, Italy, ¹⁹Rheumatology, Policlinico San Matteo, Pavia, Italy, ²⁰15 Azienda Ospedaliera San Camillo, Roma, Italy, roma, Italy, ²¹Clinical and Experimental Medicine, University of Pisa, Rheumatology Unit, Pisa, Italy, ²²Rheumatology Unit, Internal Medicine, Policlinico S.Orsola-Malpighi, Azienda Ospedaliero-Universitaria di Bologna, Bologna, Italy, ²³University Campus Biomedico, Roma, Italy, roma, Italy, ²⁴Ospedale of Bolzano, Bolzano, Italy, bolzano, Italy, ²⁵A.O.U. Policlinico Vittorio Emanuele, Catania, Italy, catania, Italy, ²⁶Ospedali Riuniti and University of Ancona, Ancona, Italy, ancona, Italy, ²⁷Internal Medicine and Clinical Immunology, Vita-Salute San Raffaele University, Milan, Italy, ²⁸Internal Medicine, Hospital Papa Giovanni XXIII, Bergamo, Italy, ²⁹Ospedali Riuniti of Foggia, Foggia, Italy, Foggia, Italy, ³⁰Università di Pavia, Pavia, Italy, ³¹Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, Genoa, Italy, Genova, Italy, ³²Rheumatology Unit, Department of Medicine - DIMED, Department of Medicine-DIMED, University of Padova, Padova, Italy, ³³Rheumatology Unit, Vittorio-Emanuele University Hospital of Catania, Catania, Italy, ³⁴Medical Clinic Unit, Department of Internal Medicine, Ospedali Riuniti, Ancona, Italy, ³⁵Clinical and Experimental Medicine, Rheumatology Unit, University of Perugia, Italy, Perugia, Italy, ³⁶Department of Clinical and Experimental Medicine, Rheumatology Unit-Azienda Ospedaliera-Universitaria Sant'Anna, Ferrara, Italy, ³⁷Internal medicine Unit, Policlinico S. Orsola Malpighi, Bologna, Italy, ³⁸Rheumatology Department, University of Milan, Istituto Ortopedico Gaetano Pini, Milano, Italy, ³⁹Division of Rheumatology, University of Pavia School of Medicine, IRCCS Policlinico San Matteo Foundation, Pavia, Italy, ⁴⁰Rheumatology Unit, University of Pisa, Pisa, Italy, ⁴¹U.O. Reumatologia, A.O. Ospedale San Carlo, Potenza, Italy, ⁴²Rheumatology Unit, Santa Chiara Hospital, Trento, Italy, ⁴³Rheumatology, allergology and clinical immunology, University of Rome Tor Vergata, Rome, Italy, ⁴⁴Ospedale S.Croce e Carle, Cuneo, Italy, cuneo, Italy, ⁴⁵Azienda Ospedaliera of Padova, University of Padova, Padova, Italy, ⁴⁶Rheumatology Unit, Arcispedale S Maria Nuova, IRCCS, Reggio Emilia, Italy, ⁴⁷Internal Medicine- Unit of Rheumatology and Clinical Immunology, Humanitas Clinical and Research Center, Rozzano, Italy, ⁴⁸University of Milan, Milan, Italy, milano, Italy
COUNSELING ON FAMILY PLANNING AND CONTRACEPTION, AND PREGNANCY OUTCOME IN WOMEN WITH RHEUMATIC DISEASES: ANALYSIS OF 398 PATIENT-REPORTED QUESTIONNAIRES FROM A MULTICENTER ITALIAN STUDYBackground/Purpose: Rheumatic…
Abstract Number: 2436 • 2016 ACR/ARHP Annual Meeting
Birth Outcomes Significantly Worsen after the Development of Systemic Lupus Erythematosus in a Population-Based Registry
Mary Abraham¹, Lexi Rene¹, Cristina Drenkard² and S. Sam Lim³, ¹Department of Medicine, Emory University, Atlanta, GA, ²Emory University School of Medicine, Atlanta, GA, ³Medicine, Emory University School of Medicine, Atlanta, GA
Background/Purpose: SLE mothers are known to have higher rates of pre-term birth and low birth weight compared to women in the general population. We evaluated…
Abstract Number: 2437 • 2016 ACR/ARHP Annual Meeting
Causes of Cesarean Section and Labor Induction in Systemic Lupus Erythematosus and Rheumatoid Arthritis Pregnancies
Amanda M. Eudy, Laura Neil and Megan E. B. Clowse, Rheumatology, Duke University Medical Center, Durham, NC
Background/Purpose: Women with SLE and RA have an increased risk of delivering a preterm infant. However, the causes of these preterm births remain unknown. Some…
Abstract Number: 2438 • 2016 ACR/ARHP Annual Meeting
Increased Risk of Postpartum Depression in SLE Pregnancies
Evelyne Vinet¹, Susan Scott², Debbie Ehrmann Feldman³, Christian A. Pineau⁴ and Sasha Bernatsky², ¹Divisions of Rheumatology and Clinical Epidemiology, McGill University Health Centre, Montreal, QC, Canada, ²Clinical Epidemiology, Research Institute of the McGill University Health Centre, Montreal, QC, Canada, ³School of Rehabilitation, Université de Montréal, Montreal, QC, Canada, ⁴McGill University Health Centre, Montreal, QC, Canada
Background/Purpose: Chronic diseases have been shown to be a strong risk factor for postpartum depression. Although there is a 2-fold increased risk of major depression…
Abstract Number: 2439 • 2016 ACR/ARHP Annual Meeting
Effect of Pregnancy Counseling on the Outcome of Pregnancies in Women with Systemic Lupus Erythematosus: A Prospective Observational Study
Rebecca Fischer-Betz¹, Lisa Kueppers², Ralph Brinks², Oliver Sander³, Christof Specker⁴ and Matthias Schneider³, ¹Policlinic of Rheumatology and Hiller Research Unit Rheumatology, Heinrich-Heine University, Duesseldorf, Duesseldorf, Germany, ²Department of Rheumatology&Hiller Research Unit, Heinrich-Heine-University, Duesseldorf, Germany, ³Department of Rheumatology & Hiller Research Unit, Heinrich-Heine-University, Duesseldorf, Germany, ⁴Rheumatology and Clinical Immunology, Kliniken Essen Sued, Essen, Germany
Background/Purpose: Pregnancies in women with systemic lupus erythematosus (SLE) are associated with increased frequencies of adverse pregnancy outcomes (APOs). Preconception counseling including risk stratification and…
Abstract Number: 2440 • 2016 ACR/ARHP Annual Meeting
First Results from the Prospective German Pregnancy Register
Rebecca Fischer-Betz¹, Christina Bungartz², Jutta Richter¹, Angela Zink³, Matthias Schneider¹, Anja Weiss², Joachim Listing⁴ and Anja Strangfeld⁵, ¹Department of Rheumatology & Hiller Research Unit, Heinrich-Heine-University, Duesseldorf, Germany, ²German Rheumatism Research Centre, Berlin, Germany, ³Epidemiology Unit, German Rheumatism Research Center and Charité University Medicine, Berlin, Germany, ⁴German Rheumatism Research Center, Berlin, Germany, ⁵Epidemiology, German Rheumatism Research Center, Berlin, Germany
Background/Purpose: There is limited evidence on the safety of treatment during pregnancy and lactation. With the increasing number of new therapeutic options for inflammatory rheumatic…
Abstract Number: 2441 • 2016 ACR/ARHP Annual Meeting
Rheumatoid Arthritis Flares and Pregnancy Outcomes Among Women in a Longitudinal Registry
Sara K. Tedeschi, Michelle Frits, Christine Iannaccone, Michael Weinblatt, Nancy A. Shadick and Bonnie L. Bermas, Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA
Background/Purpose: Rheumatoid arthritis (RA) has been reported to improve during 50-60% of pregnancies. In this study, we evaluated RA disease activity during pregnancy and pregnancy…
Abstract Number: 2442 • 2016 ACR/ARHP Annual Meeting
Use of Nonsteroidal Anti-Inflammatory Drugs in Pregnant Women with Inflammatory Arthritis
Neda Amiri¹, Gretchen Bandoli², Diana L Johnson² and Christina D. Chambers², ¹Division of Rheumatology, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada, ²Pediatrics, University of California, San Diego, La Jolla, CA
Use of Nonsteroidal Anti-inflammatory Drugs in Pregnant Women with Inflammatory Arthritis Background/Purpose: Nonsteroidal anti-inflammatory drugs (NSAIDs) are generally contraindicated in the third trimester of pregnancy…
Abstract Number: 2443 • 2016 ACR/ARHP Annual Meeting
Pregnancy Comorbidities and Outcomes in Psoriasis and Psoriatic Arthritis: A Prospective Cohort Study
Neda Amiri¹, Gretchen Bandoli² and Christina Chambers², ¹Division of Rheumatology, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada, ²Pediatrics, University of California, San Diego, La Jolla, CA
Pregnancy Comorbidities and Outcomes in Psoriasis and Psoriatic Arthritis: A Prospective Cohort Study Background/Purpose: While there is some evidence that women with psoriasis (Pso) and…
Abstract Number: 2444 • 2016 ACR/ARHP Annual Meeting
Effects of Disease Activity and Drug Exposure on Pregnancy Outcomes with Inflammatory Arthritis
Emily Fishman¹, Kathryn H. Dao² and John J. Cush³, ¹Texas A&M HSC College of Medicine, Dallas, TX, ²Texas Health, Dallas, TX, ³Baylor Research Institute, Dallas, TX
Background/Purpose: Pregnancy is often encountered in women who have inflammatory arthritis (IA), such as rheumatoid arthritis (RA), psoriatic arthritis (PsA), juvenile arthritis (JIA) or ankylosing…
Abstract Number: 2445 • 2016 ACR/ARHP Annual Meeting
Dermatomyositis and Pregnancy: Assessment of Disease Activity and Pregnancy Outcomes Complicated By Maternal Dermatomyositis
Gopika Miller¹, Elizabeth Moore², Antonia Valenzuela³, Lorinda Chung⁴ and Victoria P. Werth⁵, ¹Medicine, Harbor UCLA Medical Center, Torrance, CA, ²Psychiatry, David Geffen School of Medicine at UCLA, Los Angeles, CA, ³Division of Immunology and Rheumatology, Stanford University School of Medicine, Palo Alto, CA, ⁴Department of Medicine, Division of Immunology and Rheumatology, Stanford University School of Medicine, Palo Alto, CA, ⁵Dermatology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA
Background/Purpose: The effect of pregnancy on Dermatomyositis (DM) disease activity and on maternal and fetal outcomes in patients with DM is unclear. Study objective is…
Abstract Number: 2446 • 2016 ACR/ARHP Annual Meeting
Infantile Hemangiomas in Infants Born to Women with Autoimmune Diseases
Chelsey Forbess Smith¹, Kenneth L Jones², Diana L Johnson² and Christina D Chambers², ¹University of California San Diego Department of Rheumatology, La Jolla, CA, ²University of California San Diego Department of Pediatrics, La Jolla, CA
Background/Purpose: Infantile Hemangiomas (IH) are the most common benign vascular tumor in infants, estimated to occur in 4-5% of the general population. Many of the…
Abstract Number: 2447 • 2016 ACR/ARHP Annual Meeting
Does a History of Abnormal Pap Smear or Preceeding HPV Infection Affect Humoral Immune Response to Quadrivalent Human Papilloma Virus (qHPV) Vaccine in Women with Systemic Lupus Erythematosus (SLE)
J. Patricia Dhar^1,2, Lynnette Essenmacher³, Renee Dhar⁴, Ardella Magee⁵, Joel Ager⁶ and Robert Sokol⁷, ¹Internal Medicine, Wayne State University School of Medicine, Detroit, MI, ²Internal Medicine, Central Michigan University College of Medicine, Saginaw, MI, ³Wayne State University School of Medicine, Detroit, MI, ⁴CMED medical student, Central Michigan University College of Medicine, Mt. Pleasant, MI, ⁵Clinical and Translational Research Center, Wayne State University, Detroit, MI, ⁶Family Medicine, Wayne State University School of Medicine, Detroit, MI, ⁷Department of Obstetrics & Gynecology, Wayne State University School of Medicine, Detroit, MI
Background/Purpose: Cervical neoplasia is increased in women with SLE. HPV types 16 & 18 account for 70% of cervical cancer. Natural HPV cervical infection generates…

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