Abstracts Archive - Page 1756 of 2607 - ACR Meeting Abstracts

Abstract Number: 2357 • 2016 ACR/ARHP Annual Meeting
Topical Application of Aceclofenac Might NOT Produce a Significant Increase of Blood Pressure in Osteoarthritic Patients – a Continuous Automated Blood Pressure Monitor Study
Marius Trandafir¹, Ruxandra Ionescu², Denisa Predeteanu³, Alma Nicu¹, MIHAI ABOBULUI⁴, Andra Rodica Balanescu⁵, Violeta Bojinca^6,7, Daniela Opris³, Violeta Vlad⁸ and Florian Berghea^5,9, ¹Sf Maria Hospital, Bucharest, Romania, ²Department of Internal Medicine and Rheumatology, University of Medicine and Pharmacy “Carol Davila”, “, Bucharest, Romania, ³University of Medicine and Pharmacy “Carol Davila”, Department of Internal Medicine and Rheumatology “Sf. Maria” Hospital, Bucharest, Romania, ⁴RCRD, BUCHAREST, Romania, ⁵Department of Internal Medicine and Rheumatology “Sf. Maria” Hospital, Bucharest, Romania, ⁶Internal Medicine and Rheumatology Department,, Carol Davila University of Medicine and Pharmacy,, Bucuresti, Romania, ⁷Sf. Maria Hospital, Bucharest, Romania, ⁸RCRD Research Center, Bucharest, Romania, ⁹Department of Internal Medicine and Rheumatology “Sf. Maria” Hospital, University of Medicine and Pharmacy “Carol Davila”, Bucharest, Romania
Background/Purpose: Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used in Osteoarthritic patients for their anti-inflammatory and pain-killer proprieties. Various reports suggest an increase in blood pressure…
Abstract Number: 2358 • 2016 ACR/ARHP Annual Meeting
High-Fat Diet Is Associated with a Higher Incidence of Radiographic Knee OA and Progression of Knee Joint Space Narrowing: Data from the Osteoarthritis Initiative
Anna Shmagel¹, Naoko Onizuka², Lisa Langsetmo³, Kristine E. Ensrud⁴ and Robert Foley⁵, ¹Rheumatic & Autoimmune Diseases, University of Minnesota, Minneapolis, MN, ²University of Minnesota, Minneapolis, MN, ³University of Minnesota School of Public Health, Minneapolis, MN, ⁴University of Minnesota and Minneapolis VAHS, Minneapolis, MN, Minneapolis, MN, ⁵Renal Diseases and Hypertension, University of Minnesota, Minneapolis, MN
Background/Purpose: Animal studies have shown that high-fat diet may increase the risk of osteoarthritis (OA), while other evidence suggests that dietary polyunsaturated fatty acids may…
Abstract Number: 2359 • 2016 ACR/ARHP Annual Meeting
Dose-Related Risks of Cardiovascular, Gastrointestinal, and Renal Adverse Events Associated with Meloxicam Among Patients with Osteoarthritis: An Observational Study Using US Claims Data
Elaine Hoffman¹, Deirdre M. Mladsi¹, Byron Cryer², William Hopkins³, D. Craig Brater⁴, Rohan Parikh¹, Ravi Goyal¹, Jordi Castellsague⁵, Dana Stafkey-Mailey⁶ and Clarence Young⁷, ¹Health Economics, RTI Health Solutions, Research Triangle Park, NC, ²University of Texas Southwestern Medical School, Dallas, TX, ³Fletcher Allen Health Care, University of Vermont College of Medicine, Burlington, VT, ⁴Indiana University School of Medicine, Bloomington, IN, ⁵Epidemiology, RTI Health Solutions, Barcelona, Spain, ⁶Xcenda, AmerisourceBergen, Palm Harbor, FL, ⁷Iroko Pharmaceuticals, LLC, Philadelphia, PA
Background/Purpose: Safety studies have shown that risks associated with non-steroidal anti-inflammatory drugs (NSAIDs) are related to dose; however, there is little evidence regarding this dose-toxicity…
Abstract Number: 2360 • 2016 ACR/ARHP Annual Meeting
The Association of Superolateral Hoffa’s Fat Pad Edema and Synovitis with Structural Changes in the Patellofemoral and Tibiofemoral Joints: The Multicenter Osteoarthritis Study
Mohamed Jarraya¹, Ali Guermazi², David T. Felson³, Frank Roemer⁴, Michael C. Nevitt⁵, James Torner⁶, Cora E. Lewis⁷ and Joshua Stefanik⁸, ¹Mercy Catholic Medical Center, Darby, PA, ²Boston University School of Medicine, Boston, MA, ³Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ⁴University of Erlangen-Nuremberg, Erlangen, Germany, ⁵Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, ⁶University of Iowa, UIowa, Iowa City, IA, ⁷Preventive Medicine, University of Alabama at Birmingham, Birmingham City, AL, ⁸Physical Therapy, Northeastern University, Boston, MA
Background/Purpose: To determine the relation of superolateral HoffaÕs fat pad (SHFP) edema and Hoffa-synovitis to cartilage damage and bone marrow lesions (BMLs) in the patellofemoral…
Abstract Number: 2361 • 2016 ACR/ARHP Annual Meeting
Association Between Osteoarthritis and Dyslipidemia: A Systematic Literature Review and Meta-Analysis
Pauline Baudart¹, Karine Louati¹, Christian Marcelli^2,3, Francis Berenbaum¹ and Jeremie Sellam¹, ¹Rheumatology dept, APHP St-Antoine hospital, Univ Paris 06, Paris, France, Paris, France, ²Rheumatology, Caen, France, ³Rheumatology dept, University Hospital Centre of Caen, Caen, France
Background/Purpose: Beyond obesity-related osteoarthritis (OA), association between metabolic syndrome and OA delineates the metabolic OA phenotype. Along this line, we aimed to investigate the prevalence…
Abstract Number: 2362 • 2016 ACR/ARHP Annual Meeting
Progression of Pain and Ultrasound Detected Synovitis in Patients with Erosive Hand Osteoarthritis over One Year
Olga Sleglova¹, Olga Ruzickova¹, Karel Pavelka¹ and Ladislav Senolt^1,2, ¹Institute of Rheumatology and Department of Rheumatology, 1st Faculty of Medicine, Charles University in Prague, Prague, Czech Republic, ²Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic
Background/Purpose: Hand osteoarthritis (HOA) is a common and frequent cause of pain. HOA is a heterogeneous group of disorders with two main subsets including non-erosive…
Abstract Number: 2363 • 2016 ACR/ARHP Annual Meeting
Synovial Changes Detected By Ultrasound and Its Association with Knee Pain: A Population-Based Case Control Study
Aliya Sarmanova^1,2, Michelle Hall³, Gwen Fernandes^2,4,5, Archan Bhattacharya^1,6, Ana Valdes^1,2,5, David Walsh^2,5,7, Michael Doherty^2,4,5 and Weiya Zhang^2,4,5, ¹Division of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, the UK, Nottingham, United Kingdom, ²Arthritis Research UK Pain Centre, Nottingham, United Kingdom, ³School of Health Sciences, University of Nottingham, the UK, Nottingham, United Kingdom, ⁴Division of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, Nottingham, United Kingdom, ⁵Arthritis Research UK Centre for Sports, Exercise and Osteoarthritis, Nottingham, United Kingdom, ⁶Arthritis Research UK Centre for Sports, Exercise and Osteoarthritis, Nottignham, United Kingdom, ⁷Division of Rheumatology, Orthopaedics and Dermatology, School of Medicine, University of Nottingham, the UK, Nottignham, United Kingdom
Background/Purpose: To examine whether synovial changes on ultrasound (US) associate with knee pain (KP) and/or underlying structural radiographic changes of osteoarthritis (OA).Methods: In this case-control…
Abstract Number: 2364 • 2016 ACR/ARHP Annual Meeting
Swimming May Associate with Less Osteoarthritis: Data from the Osteoarthritis Initiative
Grace H. Lo¹, Jeffrey B. Driban², Timothy E. McAlindon³, Charles Eaton⁴, C. Kent Kwoh⁵, Andrea Kriska⁶, Richard Souza⁷, Nancy J. Petersen⁸, Kristi Storti⁹, Marc Hochberg¹⁰, Rebecca D. Jackson¹¹, Michael C. Nevitt¹² and Maria Suarez-Almazor¹³, ¹Immunology, Allergy, Rheumatology, Baylor College of Medicine, Houston, TX, ²Rheumatology, Tufts Medical Center, Boston, MA, ³Division of Rheumatology, Tufts Medical Center, Boston, MA, ⁴Brown University, Providence, RI, ⁵Rheumatology, University of Arizona, College of Medicine, Tucson, AZ, ⁶University of Pittsburgh, Pittsburgh, PA, ⁷University of California, San Francisco, San Francisco, CA, ⁸Medicine, Baylor College of Medicine, Houston, TX, ⁹Department of Kinesiology, Health and Sport Science, Indiana University of Pennsylvania, Indiana, PA, USA, Indiana, PA, ¹⁰Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, ¹¹Ohio State University, Columbus, OH, ¹²Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, ¹³Section of Rheumatology and Clinical Immunology, Department of General Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA., Houston, TX
Background/Purpose: Swimming is a non-weight-bearing exercise often recommended to people with knee OA because it is viewed as being less harmful to the knee despite…
Abstract Number: 2365 • 2016 ACR/ARHP Annual Meeting
The Cross-Sectional and Longitudinal Associations Between Metabolic Syndrome and Hand Osteoarthritis – Data from the Framingham Study
Mette P. Strand¹, Tuhina Neogi², Jingbo Niu², David T. Felson^3,4 and Ida K. Haugen⁵, ¹Medical Faculty, University of Oslo, Oslo, Norway, ²Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ³Arthritis Research UK Centre for Epidemiology, Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom, ⁴Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, ⁵Rheumatology, Diakonhjemmet Hospital, Oslo, Norway
Background/Purpose: The association between osteoarthritis (OA) and metabolic syndrome (MetS) is controversial. Hand OA, and especially erosive hand OA (1), may be more strongly…
Abstract Number: 2366 • 2016 ACR/ARHP Annual Meeting
The Clinical Utility of the Bulge Sign in Evaluating Knee Osteoarthritis
Fatimah Al Eid¹, Timothy E. McAlindon², Ming Zhang³ and Jeffrey Driban³, ¹Rheumatology, Tufts Medical Center, Boston, MA, ²Division of Rheumatology, Tufts Medical Center, Boston, MA, ³Tufts Medical Center, Boston, MA
Background/Purpose: Despite clinicians commonly using the bulge sign test to assess presence of knee effusion, prior studies have questioned the validity of the test to…
Abstract Number: 2367 • 2016 ACR/ARHP Annual Meeting
Association Between MRI-Detected Osteophytes and Changes in Knee Pain and Structures in Older Adults: A Population Based Cohort Study
Zhaohua Zhu¹, Laura Laslett², Xingzhong Jin³, Weiyu Han¹, Benny Samuel Eathakkattu Antony⁴, Xia Wang⁵, Flavia M Cicuttini⁶, Graeme Jones^7,8 and Changhai Ding⁷, ¹Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia, ²Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia, ³Menzies institute for Medical Research, University of Tasmania, Hobart, Australia, ⁴Musculoskeletal, Menzies Research Institute Tasmania, University of Tasmania, Hobart, Australia, ⁵Menzies institute for medical research, University of Tasmania, Hobart, Australia, ⁶Monash University, Department of Epidemiology and Preventive Medicine, Melbourne, Australia, ⁷Musculoskeletal Unit, Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia, ⁸Musculoskeletal Unit, Menzies Research Institute Tasmania, University of Tasmania, Hobart,7000, Australia
Background/Purpose: Osteophyte (OP) formation is one of the clinical features of osteoarthritis (OA), so early detection of OP formation can be of diagnostic value. OP…
Abstract Number: 2368 • 2016 ACR/ARHP Annual Meeting
Analysis of Pain and Function Components in Omeract-Oarsi Strict Responders from a Randomized, Double-Blind, Placebo-Controlled, Phase 1 Study of a Novel, Intra-Articular, Injectable, Wnt Inhibitor (SM04690) in the Treatment of Osteoarthritis of the Knee
Vibeke Strand¹, Christopher J. Swearingen², Ismail Simsek², Anita DiFrancesco², Jeymi Tambiah² and Yusuf Yazici², ¹Stanford University School of Medicine, Palo Alto, CA, ²Samumed, LLC, San Diego, CA
Background/Purpose: Knee osteoarthritis (OA) is characterized by pain, functional impairment, disability, and joint space narrowing due to degradation of articular cartilage and bone remodeling. The…
Abstract Number: 2369 • 2016 ACR/ARHP Annual Meeting
Obesity and Severity of Joint Space Narrowing Are Associated with Viscosupplementation Failure in Patients with Knee Osteoarthritis. Post-Hoc Analysis of a Double-Blind, Controlled, Multicentre, Randomized Trial
Florent Eymard¹, Xavier Chevalier² and Thierry Conrozier³, ¹Department of Rheumatology, APHP Henri Mondor Hospital, Paris, France, ²Rheumatology, Hopital Henri Mondor, Créteil, France, ³Department of Rheumatology,, Nord Franche-Comté Hospital, Belfort, France
Background/Purpose: Viscosupplementation (VS) is still controversial. One of the key points is the lack of well-identified factors of response. We aimed to identify clinical…
Abstract Number: 2370 • 2016 ACR/ARHP Annual Meeting
Factors Affecting Interval Changes in Perceived Fatigue over Five Years in Patients with Rheumatoid Arthritis Compared with Osteoarthritis
Simon Stebbings^1,2, Gareth Treharne³, J. Haxby Abbott⁴ and Andrew Gray⁵, ¹Dunedin Hospital, Department of Rheumatology, Dunedin, New Zealand, ²Department of Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand, ³Psychology, University of Otago, Dunedin, New Zealand, ⁴Centre for Musculoskeletal Outcomes Research, Department of Surgical Sciences, University of Otago, Dunedin, New Zealand, ⁵Department of Preventive and Social Medicine, University of Otago, Dunedin, New Zealand
Background/Purpose: In a previous cross-sectional study we noted higher fatigue levels in patients with advanced lower limb OA compared with RA, and identified differences in…
Abstract Number: 2371 • 2016 ACR/ARHP Annual Meeting
Effect of Etanercept on Several Soluble Biomarkers in a Randomized Controlled Trial of Patients with Erosive Hand Osteoarthritis
Féline Kroon¹, Ruth Wittoek², Wing-Yee Kwok¹, Klaus Bobacz³, Dirk Elewaut², Marta Favero⁴, Tom Huizinga⁵, Josef Smolen³, Bert Vander Cruyssen², Ron Wolterbeek⁶, Leonardo Punzi⁷, Gust Verbruggen², Margreet Kloppenburg⁸ and Roberta Ramonda⁷, ¹Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ²Rheumatology, Ghent University Hospital, Ghent, Belgium, ³Internal Medicine III, Div. of Rheumatology, Medical University of Vienna, Vienna, Austria, ⁴Rheumatology Unit,Department of Medicine–DIMED, University of Padova, Rheumatology Unit,University of Padova, Padova, Italy, ⁵Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁶Medical Statistics and Bioinformatics, Leiden University Medical Center, Leiden, Netherlands, ⁷Rheumatology Unit, Department of Medicine DIMED, University of Padova, Padova, Italy, ⁸Rheumatology and Clinical Epidemiology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: Erosive hand osteoarthritis (OA) is a hand OA subset with high disease burden, although effective therapies are still lacking and clinical trials are scarce.…

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