Abstract Number: 2342 • 2016 ACR/ARHP Annual Meeting
Understanding Patient Barriers and Facilitators to Healthy Eating and Physical Activity before and after Knee Replacement
Background/Purpose: Knee replacement typically results in reduced pain and improved physical function, yet post-operative physical activity levels often remain unchanged. Many patients also gain weight…Abstract Number: 2343 • 2016 ACR/ARHP Annual Meeting
A Phase 2, Multi-Center, Randomized, Double-Blind, Active-Controlled, Parallel Group Study to Evaluate the Safety and Dose Effectiveness of Intradermal Injections of Purified Apis Mellifera Toxin to Improve Pain and Physical Function in Patients with Osteoarthritis of the Knee
Background/Purpose: This Phase 2a/b trial evaluated the safety and dose effectiveness of honeybee toxin (purified Apis melliferatoxin) injections to improve pain and physical function in…Abstract Number: 2344 • 2016 ACR/ARHP Annual Meeting
Inflammation and Glucose Homeostasis Are Associated with Specific Structural Features Among Adults without Knee Osteoarthritis
Background/Purpose: Adults with osteoarthritis (OA) have greater glucose concentrations and inflammation. It remains unclear if inflammation and glucose homeostasis are related to specific features of…Abstract Number: 2345 • 2016 ACR/ARHP Annual Meeting
Relation of Varus Knee Thrust during Walking to Two-Year Incidence of Frequent Ankle, Hip, and Lower Back Pain
Background/Purpose: Varus knee thrust is an abrupt change in frontal plane alignment of the tibiofemoral joint observed during gait. Thrust has been previously linked to…Abstract Number: 2346 • 2016 ACR/ARHP Annual Meeting
The Improving Motivation for Physical Activity in Arthritis Clinical Trial for Adults with Knee Osteoarthritis and Rheumatoid Arthritis
Abstract: Background/Purpose: Insufficiently active adults experience reduced quality of life. Because half of adults with arthritis are physically inactive, we evaluated the additional effect of…Abstract Number: 2347 • 2016 ACR/ARHP Annual Meeting
Serum Levels of Resistin Are Associated with Synovial Inflammation and Knee Structural Changes in Patients with Symptomatic Knee Osteoarthritis
Background/Purpose: Due to these sparse and inconsistent clinical data, our current study aims to describe the associations between serum levels of resistin, knee synovial inflammation…Abstract Number: 2348 • 2016 ACR/ARHP Annual Meeting
Does Arthritis in Other Joints and Spine Influence the 1-Year Outcome of Total Hip Replacement? a Prospective European Multicenter Cohort Study Measuring the Influence of Musculoskeletal Morbidity
Background/Purpose: Whilst arthritis in other affected joints and back pain is known to lead to worse outcomes following total hip replacement surgery, these risk factors…Abstract Number: 2349 • 2016 ACR/ARHP Annual Meeting
Longitudinal Construct Validity for Four Patient-Reported Outcomes Measurement Information System (PROMIS) Short Forms: Physical Function, Pain Interference, Depression, and Anxiety Among Adults with Knee Osteoarthritis
Background/Purpose: Patient-Reported Outcomes Measurement Information System (PROMIS) provides clinicians and researchers access to reliable, valid measures of health status to resolve many challenges associated…Abstract Number: 2350 • 2016 ACR/ARHP Annual Meeting
Radiographic Outcomes from a Randomized, Double-Blind, Placebo-Controlled, Phase 1 Study of a Novel, Intra-Articular, Injectable, Wnt Inhibitor (SM04690) in the Treatment of Osteoarthritis of the Knee
Background/Purpose: Knee osteoarthritis (OA) is characterized by pain, functional impairment, disability, and joint space narrowing due to degradation of articular cartilage and bone remodeling. The…Abstract Number: 2351 • 2016 ACR/ARHP Annual Meeting
Racial Differences in Magnetic Resonance Image-Based Three-Dimensional Bone Shape of the Knee: Data from the Osteoarthritis Initiative (OAI)
Background/Purpose: African Americans have higher prevalence and greater severity of knee osteoarthritis (OA) on radiographs compared with Caucasians. Magnetic resonance imaging (MRI)-based quantification of 3-dimensional…Abstract Number: 2352 • 2016 ACR/ARHP Annual Meeting
Obesity-Related Systemic Inflammation and Knee Synovitis
Background/Purpose: Obesity, a major risk factor for knee osteoarthritis (OA), is a state of systemic inflammation through elaboration of adipokines (pro and anti-inflammatory cytokines) from…Abstract Number: 2353 • 2016 ACR/ARHP Annual Meeting
Radiographic Variations in Hip Morphology Are Associated with Hip Symptoms: A Cross-Sectional Analysis of a Large Community-Based Cohort
Background/Purpose: Preliminary investigation in this cohort supported an association between hip morphology and symptoms, however, the influence of race, gender, age, BMI and radiographic hip…Abstract Number: 2354 • 2016 ACR/ARHP Annual Meeting
Pharmaceutical Grade Chondroitin Sulfate Improves Knee Osteoarthritis Symptoms More Than Placebo and As Much As Celecoxib: Results of the Chondroitin Vs Celecoxib Vs Placebo Trial (CONCEPT)
Background/Purpose: For the assessment of Symptomatic Slow Acting Drugs in Osteoarthritis (SYSADOAs), regulatory Agencies request the assessment of two co-primary endpoints: pain and function. They…Abstract Number: 2355 • 2016 ACR/ARHP Annual Meeting
Histology of Bone Marrow Lesions in Osteoarthritis: A Systematic Literature Review
Background/Purpose: Bone marrow lesions (BMLs) are of high interest in osteoarthritis for their association with pain and structural progression. They are characterized on magnetic resonance…Abstract Number: 2356 • 2016 ACR/ARHP Annual Meeting
Comparison of Spa Therapy with or without Physical Rehabilitation for Knee Osteoarthritis: A Randomized Controlled Trial
Background/Purpose: To demonstrate the non-inferiority of “Active” compared to “Standard” spa therapy at 6 months in symptomatic knee osteoarthritis (KOA) care. Methods: Prospective, randomized, monocenter,…
