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  • Abstract Number: 834 • 2015 ACR/ARHP Annual Meeting

    The Efficacy of Rituximab in Systemic Sclerosis Joint Disease: A Pilot Study

    Helena Borrell Paños1, Javier Narváez2, Juan José Alegre3, Ivan Castellvi4, Gloria Albert Espi3, Sergi Heredia1, Elide Toniolo4 and Joan Miquel Nolla1, 1Department of Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, 2Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, 3Rheumatology Department, Hospital Universitario Doctor Peset, Valencia, Spain, 4Rheumatology Unit. Hospital de la Santa Creu i Sant Pau, Barcelona, Spain

    Background/Purpose: Between 16 and 20% of patients with systemic sclerosis (SS) have arthritis, which is occasionally erosive. In addition, between 1 and 5% of patients…
  • Abstract Number: 835 • 2015 ACR/ARHP Annual Meeting

    A Meta-Analysis to Determine If the Prevalence of Scleroderma Renal Crisis Decreasing with Time

    Matthew Turk1 and Janet E. Pope2, 1Medicine/Rheumatology, University of Western Ontario, London, ON, Canada, 2University of Western Ontario, London, ON, Canada

    Background/Purpose: Systemic sclerosis (scleroderma, SSc) is an autoimmune connective tissue disease with increased mortality from various internal organ involvement. Scleroderma renal crisis (SRC) usually occurs…
  • Abstract Number: 836 • 2015 ACR/ARHP Annual Meeting

    Influence of B Cell Depletion By Monoclonal Anti CD20 Antibodies in Systemic Sclerosis: Results of a Randomized Placebo Controlled Trial

    Samira Ben Said-Bouyeri1, Jessica Meijs1, Nina Ajmone Marsan2, Anne A. Schouffoer1, Maarten K. Ninaber3, Hans Ulrich Scherer4, Femke Bonte-Mineur5, T. W. J. Huizinga1 and Jeska K. de Vries-Bouwstra1, 1Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 2Cardiology, Leiden University Medical Center, Leiden, Netherlands, 3Pulmonology, Leiden University Medical Center, Leiden, Netherlands, 4Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 5Maasstad Hospital, Rotterdam, Rotterdam, Netherlands

    Background/Purpose: Systemic sclerosis (SSc) is a severe, systemic auto-immune disease with limited treatment options. Previous observational studies showed possible efficacy of Rituximab (RTX), a monoclonal…
  • Abstract Number: 837 • 2015 ACR/ARHP Annual Meeting

    Exposure to ACE Inhibitors Prior to Onset of Scleroderma Renal Crisis Is Not Associated with Increased Risk of Mortality in a Large Retrospective Cohort Study

    Sindhu R. Johnson1, Mohamed Elarabi2, Susanna Proudman3, Tracy M. Frech4, Joanne Sahhar5, Wendy Stevens6, Jane Zochling7, Zareen Ahmad8, Murray Baron9, Marie Hudson9 and Canadian Scleroderma Research Group, 1Medicine, Toronto Scleroderma Program, Toronto Western Hospital, Toronto General Hospital, Mount Sinai Hospital, and University of Toronto, Toronto, ON, Canada, 2Toronto Scleroderma Program, Toronto Western Hospital, Toronto General Hospital, Mount Sinai Hospital, and University of Toronto, Toronto, ON, Canada, 3Rheumatology Unit, Royal Adelaide Hospital North Terrace, Adelaide, Australia, 4Div of Rheumatology, University of Utah, Salt Lake City, UT, 5Department of Rheumatology, Monash Medical Centre, Melbourne, Australia, 6Rheumatology, St. Vincent’s Hospital, Melbourne, Australia, 7Royal Hobart Hospital, Tasmania, Australia, 8Division of Rheumatology, Toronto Scleroderma Program, Toronto Western Hospital, Toronto General Hospital, Mount Sinai Hospital, and University of Toronto, Toronto, ON, Canada, 9Jewish General Hospital, Lady Davis Institute and McGill University, Montreal, QC, Canada

    Background/Purpose: Scleroderma renal crisis (SRC) is a life-threatening complication of systemic sclerosis (SSc). Since the advent of angiotensin converting enzyme inhibitors (ACEI), the outcome of…
  • Abstract Number: 838 • 2015 ACR/ARHP Annual Meeting

    Impaired Quality of Life in Systemic Sclerosis and Patient Perception of the Disease: A Large International Survey

    Camelia Frantz1, Jerome Avouac1, Oliver Distler2, Fazia Amrouche1, Dominique Godard3, Ann Kennedy4, John Varga5, Marco Matucci-Cerinic6 and Yannick Allanore7, 1Paris Descartes University, Rheumatology A department, Cochin Hospital, Paris, France, 2Division of Rheumatology, University Hospital And Eular Scleroderma Trials And Research (EUSTAR) Board, Zurich, Switzerland, 3Association des Sclérodermie de France, Auxerre, France, 4Federation of European Scleroderma Associations (FESCA), Tournai, Belgium, 5Division of Rheumatology, Northwestern University, Feinberg School of Medicine, Chicago, IL, 6Rheumatology Department, University of Florence And World Scleroderma Foundation, Florence, Italy, 7Paris Descartes University, Rheumatology A department, Cochin Hospital, And Eular Scleroderma Trials And Research (EUSTAR) Board, Paris, France

    Background/Purpose: Systemic sclerosis (SSc) is recognized as one of the most fatal rheumatic diseases, but it also promotes many detrimental effects on health-related quality of…
  • Abstract Number: 839 • 2015 ACR/ARHP Annual Meeting

    Occupational Exposures in Patients with Systemic Sclerosis Associated with Increased Frequency of Interstitial Lung Disease and Primary Pulmonary Hypertension

    Brandi E. Stevens1,2, Mary Lucas3, Thomas A. Medsger Jr.4 and Robyn T. Domsic5, 1Division of Rheumatology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, 2Medicine-Rheumatology, University of Pittsburgh, Pittsburgh, PA, 3Division of Rheumatology, University of Pittsburgh, Pittsburgh, PA, 4Department of Medicine/Rheumatology, University of Pittsburgh, Pittsburgh, PA, 5Medicine - Rheumatology, University of Pittsburgh, Pittsburgh, PA

    Background/Purpose: Systemic sclerosis (SSc) has been linked with environmental and occupational exposures. Silica and solvent exposure have the strongest known correlation with SSc. Other agents,…
  • Abstract Number: 840 • 2015 ACR/ARHP Annual Meeting

    Skin Telangiectasia Identify a Subset of Systemic Sclerosis Patients with Severe Vascular Phenotype

    Jerome Avouac1, Charlotte Hurabielle2, Gemma Lepri3, Tullia De Risi4, Andre Kahan5 and Yannick Allanore6, 1Rheumatology A department and INSERM U1016, Paris Descartes University, Cochin Hospital, Paris, France, 2Rheumatology A department, paris Descartes University, Cochin Hospital, Paris, France, 3Department of Internal Medicine, Rheumatology Section, Transition Clinic, University of Florence, Italy, Florence, Italy, 4Rheumatology A department, Paris Descartes University, Cochin Hospital, Paris, France, 5Rheumatology A, Cochin Hospital, Paris Cedex 14, France, 6Paris Descartes University, Rheumatology A department, Cochin Hospital, And Eular Scleroderma Trials And Research (EUSTAR) Board, Paris, France

    Background/Purpose: Cutaneous Telangiectasia (CT) are common in systemic sclerosis (SSc) patients but their input to risk stratify the patients is poorly known. The aims of…
  • Abstract Number: 841 • 2015 ACR/ARHP Annual Meeting

    Prevalence of Systemic Sclerosis in Primary Biliary Cirrhosis Using the New ACR/EULAR Classification Criteria

    Boyang Zheng1, Catherine Vincent2, Marvin J. Fritzler3, Jean-Luc Senécal4, Martial Koenig5 and France Joyal5, 1Division of Internal Medicine, Centre Hospitalier de l'Université de Montréal, Montreal, QC, Canada, 2Division of Hepatology, Centre hospitalier de l'Université de Montréal, Montreal, QC, Canada, 3Medicine, University of Calgary, Calgary, AB, Canada, 4Department of Medicine, Division of Rheumatology, Centre Hospitalier de l’Université de Montréal, Montreal, QC, Canada, 5Department of Medicine, Division of Internal Medicine, Centre Hospitalier de l’Université de Montréal, Montreal, QC, Canada

    Background/Purpose: Systemic sclerosis (SSc) is a well established disease associated with primary biliary cirrhosis (PBC), however original 1980 American College of Rheumatology (ACR) criteria have…
  • Abstract Number: 842 • 2015 ACR/ARHP Annual Meeting

    Clinical Utility of Serial KL-6 Measurement in Interstitial Lung Disease Associated with Systemic Sclerosis

    Yuichiro Shirai1, Tsutomu Takeuchi2 and Masataka Kuwana3, 1Department of Allergy and Rheumatology, Nippon Medical School, Tokyo, Japan, Tokyo, Japan, 2Keio University School of Medicine, Tokyo, Japan, 3Department of Allergy and Rheumatology, Nippon Medical School Graduate School of Medicine, Tokyo, Japan

    Background/Purpose: Interstitial lung disease (ILD) is the leading cause of mortality in patients with systemic sclerosis (SSc). KL-6, a mucin-like glycoprotein highly expressed on type…
  • Abstract Number: 843 • 2015 ACR/ARHP Annual Meeting

    Natriuretic Peptide Predicts Mortality in Systemic Sclerosis

    Christophe Meune1, Andras Komocsi2, Serena Vettori3, Eric Hachulla4, Jerome Avouac5, Nicolas Hunzelmann6, Jorg HW. Distler7 and Yannick Allanore8, 1Cardiology department, Université Paris XIII, Hôpitaux Universitaires Paris-Seine-Saint-Denis, Bobigny, France, 2Heart Institute, University of PECS, Pecs, Hungary, 3Department of Clinical and Experimental Medicine, Rheumatology Unit, Second University of Naples, Naples, Italy, 4CHU Lille, Lille, France, 5Rheumatology A department and INSERM U1016, Paris Descartes University, Cochin Hospital, Paris, France, 6Department of Dermatology, University of Cologne, Cologne, Germany, 7Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen-Nuremberg, Erlangen, Germany, 8Paris Descartes University, Rheumatology A department, Cochin Hospital, And Eular Scleroderma Trials And Research (EUSTAR) Board, Paris, France

    Background/Purpose: Heart involvement both of primary origin or secondary to lung disease is a key contributor to morbidity and mortality in systemic sclerosis (SSc). While…
  • Abstract Number: 844 • 2015 ACR/ARHP Annual Meeting

    Identification of Subclinical Skin Involvement By High Frequency Ultrasound in Systemic Sclerosis Patients

    Barbara Ruaro, Alberto Sulli, Elena Bernero, Marco A. Cimmino, Sabrina Paolino and Maurizio Cutolo, Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, IRCCS A.O.U. San Martino-IST, University of Genova, Genoa, Italy, Genoa, Italy

    Background/Purpose: Skin involvement may be evaluated in systemic sclerosis (SSc) by modified Rodnan skin score (mRSS), the validated method to distinguish between patients with limited…
  • Abstract Number: 845 • 2015 ACR/ARHP Annual Meeting

    Modelling of Longitudinal Changes in Lung Function in Patients with Systemic Sclerosis and Their Association with Development of Pulmonary Hypertension

    Svetlana I. Nihtyanova1, Voon H. Ong1 and Christopher P. Denton2, 1Rheumatology, UCL Division of Medicine, London, United Kingdom, 2Rheumatology and Connective Tissue Diseases, University College London, London, United Kingdom

    Background/Purpose: The majority of published models for prediction of PH use cross-sectional data, while studies exploring the use of repeated measurements of lung function tests…
  • Abstract Number: 846 • 2015 ACR/ARHP Annual Meeting

    Nationwide Trends in in-Hospital Mortality and Hospitalization Associated with Systemic Sclerosis (SSc)

    Sara R. Schoenfeld1, Na Lu1, Flavia V. Castelino2, Marcy B. Bolster2 and Hyon K. Choi1, 1Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 2Rheumatology, Allergy, Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: Patients with systemic sclerosis (SSc) experience high rates of morbidity and mortality, but few studies have evaluated health care utilization such as hospitalization rates…
  • Abstract Number: 847 • 2015 ACR/ARHP Annual Meeting

    Troponin T and NT-Probnp Are Prognostic Cardiac Disease Biomarkers in Patients with Systemic Sclerosis without Pulmonary Arterial Hypertension

    Silvia Laura Bosello1, Giacomo De Luca1, Franca Forni2, Clara Di Mario3, Federico parisi1, Giovanni Canestrari1, Giorgia Berardi1, Manuela Rucco1, Francesca Gabrielli4, Leonarda Galiuto4, Francesco Loperfido4 and Gianfranco Ferraccioli1, 1Division of Rheumatology, Catholic University of the Sacred Heart, Rome, Italy, 2Department of Laboratory Medicine, Catholic University of the Sacred Heart, Rome, Italy, 3Division of Rheumatology, Institute of Rheumatology, Catholic University of the Sacred Heart, Rome, Italy, 4Division of Heart Failure and Cardiac Rehabilitation, Catholic University - Rome, Rome, Italy

    Background/Purpose: Heart involvement is common in Systemic Sclerosis (SSc), even if often clinically silent, and represents one of the leading cause of death in these…
  • Abstract Number: 848 • 2015 ACR/ARHP Annual Meeting

    Nitroglycerin Patch Application in Systemic Sclerosis: Evaluation By Laser Doppler Imaging

    Georgiana Bentea, Aurelien Wauters, Jean-Claude Wautrecht and Elie Cogan, Erasme Hospital, Brussels, Belgium

    Background/Purpose: Systemic sclerosis (SSc) is a complex autoimmune disease, commonly associated with Raynaud phenomenon (RP). The aim of this study was to characterize the microvascular…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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