ACR Meeting Abstracts

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  • Abstract Number: 397 • 2015 ACR/ARHP Annual Meeting

    Longitudinal Observation of Psychological Factors and Health-Related Quality of Life in Childhood-Onset Lupus

    Catherine Donnelly1, Jordan T. Jones2, Ji Li3, Natoshia Cunningham4, Susmita Kashikar-Zuck5 and Hermine I. Brunner2, 1Internal Medicine, University of Cincinnati, Cincinnati, OH, 2Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 3Department of Pediatrics, Peking Union Medical College Hospital, Beijing, China, 4Behavioral Medicine & Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 5Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH

    Background/Purpose: Childhood-onset Lupus (cSLE) is associated with decreased Health-related Quality of Life (HRQoL), and disease activity measures are often unrelated to overall perception of health. The…
  • Abstract Number: 398 • 2015 ACR/ARHP Annual Meeting

    Clinical and Serological Profile of Children with Positive SSA-Ro/SSB-La Antibodies

    Juan G. Ovalles-Bonilla1, Juan C. Nieto1, Francisco Javier López Longo1, Julia Martínez-Barrio2, Iustina Janta1, Esperanza Naredo1, Carlos M. Gonzalez1, Michelle Hinojosa1, Natalia Bello1, Belen Serrano1, Carmen Mata1, Claudia Sáenz Tenorio1, Diana C. Hernández1, Lara Valor1, Indalecio Monteagudo1 and Luis Carreño1, 1Rheumatology, Hospital General Universitario Gregorio Marañón, Madrid, Spain, 2Servicio de Reumatologia, Hospital General Universitario Gregorio Marañón, Madrid, Spain

    Background/Purpose: Several studies have shown the relationship between anti-SSA-Ro/SSB-La antibodies and Systemic Lupus Erythematosus (SLE), Sjögren Syndrome (SS) and other autoimmune diseases in adult population.…
  • Abstract Number: 399 • 2015 ACR/ARHP Annual Meeting

    Management of Lupus Anticoagulant Hypoprothrombinemia Syndrome in Juvenile Systemic Lupus Erythematosus – Single Center Experience

    J. Brian Shirley1, Patricia Rosillo1, Andrea Ramirez1 and Anna Carmela Sagcal-Gironella2, 1Allergy, Immunology and Rheumatology, Baylor College of Medicine/Texas Children's Hospital, Houston, TX, 2Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, TX

    Background/Purpose: Lupus anticoagulant hypoprothrombinemia syndrome (LAHS) is a rare phenomenon that leads to concomitant thrombosis and hemorrhage thus presenting a therapeutic dilemma. In children, this…
  • Abstract Number: 400 • 2015 ACR/ARHP Annual Meeting

    Disease Activity and Health Care Utilization Among Young Adults with Childhood-Onset Lupus Transitioning to Adult Care: Data from the Pediatric Lupus Outcomes Study

    Erica F. Lawson1 and Aimee O. Hersh2, 1Pediatrics/Rheumatology, UC San Francisco, San Francisco, CA, 2Pediatrics/Rheumatology, University of Utah, Salt Lake City, UT

    Background/Purpose: Individuals with childhood-onset systemic lupus erythematosus (cSLE) must transfer from pediatric- to adult-oriented health care as they enter adulthood. However, few studies have assessed…
  • Abstract Number: 401 • 2015 ACR/ARHP Annual Meeting

    Racial and Ethnic Disparities in Depression Diagnosis and Treatment for Adolescents with SLE: Analysis of a National Medicaid Sample

    Andrea Knight1, Ming Xie2 and David Mandell3, 1Pediatrics/Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, 2University of Pennsylvania, Center for Mental Health Policy and Services Research, Philadelphia, PA, 3Psychiatry and Pediatrics, University of Pennsylvania, Center for Mental Health Policy and Services Research, Philadelphia, PA

    Background/Purpose: Adolescents with systemic lupus erythematosus (SLE) are at high risk for depression. Racial/ethnic minorities are disproportionately affected by SLE, and previous studies suggest a…
  • Abstract Number: 402 • 2015 ACR/ARHP Annual Meeting

    Predicting Area Under the Curve of Mycophenolate Mofetil in Childhood-Onset Systemic Lupus Erythematosus

    Roberto Ezequiel Borgia1, Masanobu Takeuchi2, Deborah M. Levy3, Shinya Ito‎4 and Earl Silverman5, 1Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, 2Program of Physiology & Experimental Medicine, Peter Gilgan Centre For Research and Learning (PGCRL), The Hospital for Sick Children, Toronto ON, Toronto, ON, Canada, 3Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, 43Division of Clinical Pharmacology and Toxicology, The Hospital for Sick Children Toronto ON, Toronto, ON, Canada, 5Division of Rheumatology, Hospital for Sick Children and University of Toronto, Toronto, ON, Canada

    Background/Purpose: Mycophenolate mofetil (MMF) is an immunosuppressive drug used off-label for the treatment of childhood-onset systemic lupus erythematosus (cSLE). Therapeutic drug monitoring (TDM) of MMF’s…
  • Abstract Number: 403 • 2015 ACR/ARHP Annual Meeting

    Proteinuria in Childhood Onset Lupus Nephritis: When Does It Go Away ?

    Justin Hung Tiong Tan1, Sook Fun Hoh2, Manasita Tanya1, Lena Das1, Ma Thin Mar Win3, Yiong Huak Chan3 and Thaschawee Arkachaisri1,4, 1Rheumatology and Immunology, KK Women's and Children's Hospital, Singapore, Singapore, 2Nursing, KK Women's and Children's Hospital, Singapore, Singapore, 3Biostatistics Unit, Yong Loo Lin School of Medicine, Singapore, Singapore, 4Paediatrics, Duke-NUS Graduate Medical School, Singapore, Singapore

    Background/Purpose: The time to recovery from proteinuria in patients with lupus nephritis (LN) receiving standard treatment has been described in adult, but not in children.…
  • Abstract Number: 404 • 2015 ACR/ARHP Annual Meeting

    Long-Term Outcomes of Macrophage Activation Syndrome in Childhood-Onset Systemic Lupus Erythematosus

    Roberto Ezequiel Borgia1, Maya Gerstein1, Deborah M. Levy2, Earl Silverman2 and Linda T Hiraki2, 1Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, 2The Hospital for Sick Children, Toronto, ON, Canada

    Background/Purpose: Macrophage activation syndrome (MAS) is a life-threatening inflammatory complication of childhood-onset systemic lupus erythematosus (cSLE). There are few reports of long-term outcomes of MAS complicating cSLE.…
  • Abstract Number: 405 • 2015 ACR/ARHP Annual Meeting

    Anti-C1q Antibodies As Potential Diagnostic and Prognostic Biomarkers in Juvenile Systemic Lupus Erythematosus

    Thaschawee Arkachaisri1,2, Justin Hung Tiong Tan1, Manasita Tanya1, Sook Fun Hoh3, Lena Das4 and Jing Yao Leong5,6, 1Rheumatology and Immunology, KK Women's and Children's Hospital, Singapore, Singapore, 2Paediatrics, Duke-NUS Graduate Medical School, Singapore, Singapore, 3Nursing, KK Women's and Children's Hospital, Singapore, Singapore, 4Dept of Rheumatology, Cincinnati Children`s Hospital Medical Center, Cincinnati, OH, 5Duke-National University of Singapore Graduate Medical School, Singapore, Singapore, 6SingHealth Translational Immunology and Inflammation Centre, Singapore Health Services Pte Ltd, Singapore, Singapore

    Background/Purpose: Anti-C1q antibodies (AC1q) were shown to strongly correlate with the occurrence and activity of lupus nephritis in adult SLE. Data of the antibodies in…
  • Abstract Number: 406 • 2015 ACR/ARHP Annual Meeting

    Long Term Follow up of Inner City Pediatric Patients with Lupus Nephritis

    Janice Desir1, Beatrice Goilav2, Ellen Silver3 and Irene Blanco4, 1Pediatric Nephrology, Children's Hospital at Montefiore/Albert Einstein College of Medicine, Bronx, NY, 2Division of Nephrology, Children's Hospital at Montefiore, Bronx, NY, 3Pediatrics, Albert Einstein College of Medicine, Bronx, NY, 4Medicine, Albert Einstein College of Medicine, Bronx, NY

    Background/Purpose: In children with SLE, 80% have renal involvement, which is a major prognostic factor for both morbidity and mortality. Few studies have focused on…
  • Abstract Number: 407 • 2015 ACR/ARHP Annual Meeting

    Inter-Observer Variability of the Histological Classification of Lupus Glomerulonephritis in Children

    Louise Oni1, Michael Beresford2, David Witte3, Anastasios Chatzitolios4, Neil Sebire5, Rajeev Shukla6, Jun Ying7 and Hermine I. Brunner8, 1Department of Paediatric Nephrology, Alder Hey Children's Hospital, Liverpool UK, Liverpool, England, 2University of Liverpool, Institute of Translational Medicine (Child Health), Alder Hey Children's Foundation NHS Trust, Liverpool, United Kingdom, 3Rheumatology, Cincinnati Children's Hospital, Cincinnati, OH, 4Department of Histopathology, Southmead Hospital, Bristol, UK, Bristol, England, 5Department of Paediatric Histopathology, Great Ormond Street Hospital for Children NHS Trust, London, England, 6Department of Paediatric Histopathology, Alder Hey Children's Hospital, Liverpool UK, Liverpool, England, 7Center for Biostatistical Services, University of Cincinnati College of Medicine, Cincinnati, OH, 8Pediatric Rheumatology Collaborative Study Group, Cincinnati Children's Hospital Medical Center, Cincinnati, OH

    Background/Purpose: The gold standard for diagnosis and classification of lupus nephritis (LN) is according to the renal histology. The inter-observer reliability between histologists is variable.…
  • Abstract Number: 408 • 2015 ACR/ARHP Annual Meeting

    Characterization of Pediatric Systemic Lupus Erythematosus with Acquired Angioedema

    Marietta De Guzman1, Diana Bayer2, Roshni Sambasivan3, Debra Canter4, Martha Curry5 and Anna Carmela Sagcal-Gironella6, 1Pediatric Immunology, Allergy, and Rheumatology, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, 2Division of Allergy, Immunology andPulmonology, University of Iowa Carver College of Medicine, Iowa, IA, 3Pediatric Immunology, Allergy and Rheumatology, Baylor College of Medicine, Texas Children’s Hospital, Houston, TX, 4Pediatric Immuology, Allergy and Rheumatology, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, 5Pediatric Immunology, Allergy and Rheumatology, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, 6Pediatrics, Baylor College of Medicine, Texas Children's Hospital, Houston, TX

    Background/Purpose: Acquired angioedema, defined as non-hereditary angioedema without associated urticaria, is an uncommon but potentially life-threatening feature among adults with systemic lupus erythematosus (SLE).  Although…
  • Abstract Number: 409 • 2015 ACR/ARHP Annual Meeting

    Disease Activity, Disease Damage and Predictive Factors in Juvenile Onset Mixed Connective Tissue Disease – a Norwegian Nationwide Study

    Siri Opsahl Hetlevik1, Berit Flatø1,2, Marite Rygg3,4, Ellen Berit Nordal5 and Vibke Lilleby6, 1Department of Rheumatology, Oslo University Hospital, Rikshospitalet, Oslo, Norway, 2Department of Rheumatology, Oslo University Hospital, Institute for Clinical Medicine, University of Oslo, Oslo, Norway, 3Department of Pediatrics, St Olav University Hospital, Trondheim, Norway, 4Department of Laboratory Medicine, Children's and Women's health, Norwegian University of Science and Technology, Trondheim, Norway, 5Department of Pediatrics, University Hospital of North Norway, Tromsø, Norway, 6Rheumatology, Oslo University Hospital, Oslo, Norway

    Background/Purpose: Mixed Connective Tissue Disease (MCTD) is a rare rheumatic disease with overlapping features from Systemic Lupus Erythematosus (SLE), Systemic Sclerosis (SSc) and Polymyositis. Juvenile…
  • Abstract Number: 410 • 2015 ACR/ARHP Annual Meeting

    Characteristics of the Juvenile Systemic Sclerosis Cohort within the Childhood Arthritis and Rheumatology Research Alliance (CARRA) Registry

    Brandi E. Stevens1, Kathryn S. Torok2, Suzanne C. Li3, Nicole Hershey1, Megan Curran4, Gloria C. Higgins5, Katharine Moore6, C. Egla Rabinovich7, Anne M. Stevens8 and Childhood Arthritis and Rheumatology Research Alliance, Stanford, CA, 1Division of Rheumatology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, 2Pediatric Rheumatology, Scleroderma Center of Pittsburgh, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA, 3Pediatrics, Joseph M Sanzari Children’s Hospital, Hackensack University Medical Center, Hackensack, NJ, 4Pediatric Rheumatology, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, 5Pediatric Rheumatology Ohio State University, Nationwide Childrens Hospital, Columbus, OH, 6Pediatric Rheumatology, Seattle Children's Hospital, Seattle, WA, 7Pediatric Rheumatology, Duke University Medical Center, Durham, NC, 8Seattle Children's Res Inst, Seattle Children's Hospital, University of Washington, Seattle, WA

    Background/Purpose: Systemic sclerosis (SSc) is a rare multisystem autoimmune disease characterized by vasculopathy and organ fibrosis. We present baseline data on the North American observational…
  • Abstract Number: 411 • 2015 ACR/ARHP Annual Meeting

    Patient Reported Outcomes in Juvenile Dermatomyositis: Assessing the Importance of Different Measures to Patients and Families

    Heather Tory1, Ruy Carrasco2, Thomas Griffin3, Melissa M. Hazen4, Adam M. Huber5, Philip Kahn6, Angela Byun Robinson7, Susan Kim8 and The Childhood Arthritis and Rheumatology Research Alliance Juvenile Dermatomyositis Quality Measures Workgroup, 1Rheumatology, Connecticut Children's Medical Center, Hartford, CT, 2Pediatric Rheumatology, Specially For Children, Austin, TX, 3Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 4Rheumatology, Children's Hospital Boston, Boston, MA, 5Pediatric rheumatology, IWK Health Centre, Halifax, NS, Canada, 6Pediatric Rheumatology, New York University, New York, NY, 7Pediatrics, Rainbow Babies & Children's Hospital / Case Medical Center, Cleveland, OH, 8Division of Immunology, Boston Children's Hospital, Boston, MA

    Background/Purpose: Patient reported outcomes (PROs) are becoming increasingly important in the care of patients with chronic disease. Involving patients in their own care significantly improves…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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