ACR Meeting Abstracts

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  • Abstract Number: 382 • 2015 ACR/ARHP Annual Meeting

    Twelve Months after Osteoporosis Associated Fracture – Has Adequate Therapy Been Initiated?

    Christoph Hemmeler1, Sabrina Morell2, Paul Hasler1 and Thomas Gross2, 1Rheumatology, Kantonsspital Aarau, Aarau, Switzerland, 2Traumatology, Kantonsspital Aarau, Aarau, Switzerland

    Background/Purpose: Evidence shows that of ten patients taking medication against osteoporosis one will avoid subsequent fractures, decreasing the risk by > 50 %. On the…
  • Abstract Number: 383 • 2015 ACR/ARHP Annual Meeting

    Stiffness Index Study in Ehler Danlos Syndrome

    Chandralekha Ashangari, Henykumar Patel, Neelesh Gupta and Amer Suleman, DEPARTMENT OF CARDIOLOGY, THE HEARTBEATCLINIC, DALLAS, TX

    Background/Purpose: Ehlers-Danlos syndrome is a group of inherited disorders that affects connective tissues primarily skin, joints and blood vessel walls. Ehlers-Danlos syndromes usually have overly…
  • Abstract Number: 384 • 2015 ACR/ARHP Annual Meeting

    Dental Treatments, Tooth Extraction, and Osteonecrosis at Jaw in Japanese Patients with Rheumatoid Arthritis; Results from the IORRA Cohort Study

    Takefumi Furuya, Shigeki Momohara, Atsuo Taniguchi and Hisashi Yamanaka, Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan

    Background/Purpose: Oral health is an important issue for the patients with rheumatoid arthritis (RA) because many RA patients were treated with bisphosphonates and bisphosphate use…
  • Abstract Number: 385 • 2015 ACR/ARHP Annual Meeting

    Urinary Cell-Free Microrna’s As Biomarkers of Lupus Nephritis in Children

    Khalid Abulaban1, Ndate Fall2, Jun Ying3, Kasha Wiley4, Ravi Nunna3, Prasad Devarajan5, Alexei A. Grom4, Michael Bennett6, Stacy P. Ardoin7 and Hermine I. Brunner8, 1Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2Division of Rheumatology, Cincinnati Children's Hospital, Cincinnati, OH, 3University of Cincinnati, Cincinnati, OH, 4Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 5Dept of Nephrology, Cincinnati Children`s Hospital Medical Center, Cincinnati, OH, 6Division of Nephrology, Cincinnati Children`s Hospital Medical Center, Cincinnati, OH, 7Pediatric & Adult Rheumatology, Ohio State University, Columbus, OH, 8Pediatric Rheumatology Collaborative Study Group, Cincinnati Children's Hospital Medical Center, Cincinnati, OH

    Background/Purpose: MicroRNAs (miRNAs) are single-stranded RNAs involved in the regulation of host genome expression at the post-transcriptional level. The objective of this study was to…
  • Abstract Number: 386 • 2015 ACR/ARHP Annual Meeting

    Chronic Arthritis in Systemic Lupus Erythematosus: Distinct Features in 336 Pediatric and 1,830 Adult Patients

    Natali W. Gormezano1, Clovis A Silva2, Nadia E Aikawa3, Diego L. Barros4, Mariana A. da Silva4, Carini I. Otsuzi4, Katia T. Kozu5, Luciana Seguro4, Rosa M R Pereira6 and Eloisa Bonfá4, 1Pediatric Rheumatology Unit, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 2Pediatric Rheumatology, Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, Brazil, 3Rheumatology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 4Rheumatology Division, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 5Pediatrics, Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, Brazil, 6Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil

    Background/Purpose: Acute articular involvement is an important feature of childhood systemic lupus erythematosus (cSLE) and adult-onset (aSLE) patients, and it has been described in up…
  • Abstract Number: 387 • 2015 ACR/ARHP Annual Meeting

    Features of 847 Childhood-Onset Systemic Lupus Erythematousus Patients in Three Age-Related Groups at Diagnosis: A Brazilian Multicenter Study

    Clovis A Silva1, Roberta C. Gomes Sr.2, Marco F. Silva3, Katia T. Kozu4, Eloisa Bonfá5, Rosa M R Pereira6, Maria Teresa Terreri7, Claudia S. Magalhães Sr.8, Silvana B. Sacchetti Sr.9, Roberto Marini Sr.10, Melissa Fraga11, Luciana M. Carvalho Sr.12, Cássia M. Barbosa13 and Magda Carneiro-Sampaio Sr.14, 1Pediatric Rheumatology, Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, Brazil, 2Pediatric Rheumatology Unit, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 3Pediatric Rheumatology Unit-Children’s Institute,, Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, Brazil, 4Pediatrics, Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, Brazil, 5Division of Rheumatology, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 6Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, 7Pediatrics, Universidade Federal de Sao Paulo, São Paulo, Brazil, 8Pediatric Rheumatology Unit, São Paulo State University – Faculdade de Medicina de Botucatu, São Paulo, Brazil, 9Pediatric Rheumatology Unit, Irmandade da Santa Casa de Misericórdia de São Paulo, São Paulo, Brazil, 10Pediatric Rheumatology Unit, State University of Campinas, São Paulo, Brazil, 11Pediatrics, Universidade Federal de São Paulo / UNIFESP, São Paulo, Brazil, 12Pediatric Rheumatology Unit, Ribeirão Preto Medical School – University of São Paulo, São Paulo, Brazil, 13Pediatric Rheumatology Unit, Hospital Infantil Darcy Vargas, São Paulo, Brazil, 14Pediatric Allergology and Immunology Unit, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil

    Background/Purpose: Previous retrospective evaluations suggested that age at diagnosis may influence disease expression in terms of initial clinical presentation, pattern of organ involvement and serological…
  • Abstract Number: 388 • 2015 ACR/ARHP Annual Meeting

    Pain, Fatigue and the Psychological Impact on Health-Related Quality of Life in Childhood-Onset Lupus

    Jordan T. Jones1, Natoshia Cunningham2, Catherine Donnelly3, Susmita Kashikar-Zuck4 and Hermine I. Brunner5, 1Division of Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2Behavioral Medicine & Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 3Internal Medicine, University of Cincinnati, Cincinnati, OH, 4Behavioral Medicine and Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 5Pediatric Rheumatology Collaborative Study Group, Cincinnati Children's Hospital Medical Center, Cincinnati, OH

    Background/Purpose: Childhood-onset lupus (cSLE) is a chronic autoimmune disease that has negative impact on health-related quality of life (HRQoL), especially when increased disease activity and…
  • Abstract Number: 389 • 2015 ACR/ARHP Annual Meeting

    Clinical and Serological Differences Between Juvenile-Onset and Adult-Onset Systemic LUPUS Erythematosus Patients from a National Registry of Patients

    TC Salman-Monte1, V Torrente-Segarra2, I Rúa-Figueroa3, J Calvo-Alen4,5, FJ Lopez Longo6,7, M Galindo8,9 and JM Pego-Reigosa10, 1Rheumatology, Hospital del Mar/Parc de Salut Mar, Barcelona, Spain, 2Rheumatology, Hospital General Hospitalet-Moisès Broggi, Hospitalet Llobregat, Spain, 3Rheumatology, Hospital de GC Dr Negrin, Las Palmas GC, Spain, 4Rheumatology Division, Sierrallana Hospital, Torrelavega, Spain, 5Rheumatology, Hospital Sierrallana. Torrelavega, Torrelavega, Spain, 6Department of Rheumatology, Hospital General Universitario Gregorio Marañón, Madrid, Spain, 7Rheumatology, Gregorio Marañón Hospital, Madrid, Spain, 8Servicio de Reumatología, Instituto de Investigación Hospital 12 de Octubre (I+12), Madrid, Spain, 9Servicio de Reumatología, Hospital 12 de Octubre, Madrid, Spain, 10Rheumatology, EOXI Vigo, Vigo, Spain

    Background/Purpose: To assess clinical and serological differences between patients with juvenile-onset systemic lupus erythematosus (jSLE) and adult-onset (aSLE) from a National database.Methods: Data included in…
  • Abstract Number: 390 • 2015 ACR/ARHP Annual Meeting

    Treatment and Outcomes in Pediatric SLE Patients in South Africa

    Laura Lewandowski1, Christiaan Scott2, Laura Schanberg3 and Nathan Thielman4, 1Pediatric Rheumatology, Duke University Medical Center, Durham, NC, 2Rheumatology, Red Cross War Memorial Children's Hospital, Cape Town, South Africa, 3Duke University, Durham, NC, 4Duke Hubert Yeargan Center for Global Health, Durham, NC

    Background/Purpose:   Although African children with SLE may be at high risk for poor outcomes based on race, socioeconomic status, and age, little research has…
  • Abstract Number: 391 • 2015 ACR/ARHP Annual Meeting

    Current Provider Practices and Perceived Barriers for Mental Health Care of Adolescents with SLE

    Andrea Knight1,2,3, Michelle Vickery2, Eyal Muscal4, Alaina Davis5, Julia Harris6, Arzu Soybilgic7, Karen Onel8, Laura E. Schanberg9, Tamar Rubinstein10, Beth S. Gottlieb11, Tracey Wright12, Emily von Scheven13 and for the CARRA Investigators, 1Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, 2PolicyLab, Children's Hospital of Philadelphia, Philadelphia, PA, 3Center for Pediatric Clinical Effectiveness, Children's Hospital of Philadelphia, Philadelphia, PA, 4Pediatric Rheumatology, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, 5Pediatric Rheumatology, Vanderbilt University School of Medicine, Monroe Carell Junior Children's Hospital, Nashville, TN, 6Pediatric Rheumatology, Children’s Mercy Kansas City, Kansas City, MO, 7Pediatric Rheumatology, University of Illinois College of Medicine, Chicago, IL, 8Pediatric Rheumatology, Univ of Chicago, Chicago, IL, 9Dept of Pediatrics, Duke University Medical Center, Durham, NC, 10Division of Pediatric Rheumatology, Albert Einstein College of Medicine, Children's Hospital at Montefiore, Bronx, NY, 11Pediatric Rheumatology, The Steven and Alexandra Cohen Children's Medical Center of New York, The Hofstra North Shore-LIJ School of Medicine, New Hyde Park, NY, 12Pediatrics/Rheumatology, UT Southwestern Medical Center, Dallas, TX, 13Dept of Pediatric Rheumatology, Univ of California San Francisco, San Francisco, CA

    Background/Purpose: Depression and anxiety are common in adolescents with SLE. Barriers to mental health intervention in pediatric rheumatology care are unclear. We aimed to determine…
  • Abstract Number: 392 • 2015 ACR/ARHP Annual Meeting

    From Childhood to Adulthood: Longitudinal Trajectory of Damage in Patients with Childhood-Onset Systemic Lupus Erythematosus (cSLE)

    Lily Siok Hoon Lim1,2,3,4, Eleanor Pullenayegum5, Lillian Lim6, Dafna Gladman7, Brian Feldman8 and Earl Silverman9, 1Institute of Health Policy Management and Evaluation, University of Toronto, Toronto, ON, Canada, 2Rheumatology, SickKids, Toronto, ON, Canada, 3Rheumatology, Hospital for Sick Children, Toronto, ON, Canada, 4Children's Hospital Research Institute of Manitoba, University of Manitoba, Winnipeg, MB, Canada, 5Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada, 6Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada, 7Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 8Division of Rheumatology, The Hospital for Sick Children and University of Toronto, Toronto, ON, Canada, 9Division of Rheumatology, Hospital for Sick Children and University of Toronto, Toronto, ON, Canada

    Background/Purpose: Outcomes of patients with cSLE over time and into adulthood are poorly understood. There has been no information about the longitudinal trajectory of organ…
  • Abstract Number: 393 • 2015 ACR/ARHP Annual Meeting

    From Childhood to Adulthood: Identifying Latent Classes of Disease Activity Trajectories in Childhood-Onset Systemic Lupus Erythematosus Patients

    Lily Siok Hoon Lim1, Eleanor Pullenayegum2, Lillian Lim3, Dafna Gladman4, Brian Feldman5 and Earl Silverman6, 1Rheumatology, Hospital for Sick Children, Toronto, ON, Canada, 2Department of Clinical Epidemiology & Biostatistics, McMaster University, Hamilton, ON, Canada, 3Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada, 4Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, 5Division of Rheumatology, The Hospital for Sick Children and University of Toronto, Toronto, ON, Canada, 6Division of Rheumatology, Hospital for Sick Children and University of Toronto, Toronto, ON, Canada

    Background/Purpose: Although SLE patients are thought to follow different patterns of disease courses, no information is available about the longitudinal disease activity or the number…
  • Abstract Number: 394 • 2015 ACR/ARHP Annual Meeting

    Clinical Features of Children with Silent Lupus Nephritis

    Hiroyuki Wakiguchi1, Syuji Takei2,3, Tomohiro Kubota1, Yuichi Yamasaki1, Tsuyoshi Yamatou1, Yasuhito Nerome1, Harumi Akaike1, Yukiko Nonaka1, Tomoko Takezaki1, Hiroyuki Imanaka1 and Yoshifumi Kawano1, 1Department of Pediatrics, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan, 2School of Health Sciences, Faculty of Medicine, Kagoshima University, Kagoshima, Japan, 3Department of Pediatrics, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshma, Japan

    Background/Purpose: Lupus nephritis (LN) is the major findings in systemic lupus erythematosus (SLE). LN with some pathologic findings in the kidney but had normal urine…
  • Abstract Number: 395 • 2015 ACR/ARHP Annual Meeting

    Depression Risk Among Adults with Childhood- and Adult-Onset Systemic Lupus Erythematosus: 11 Years of Follow-up

    Erica F. Lawson1, Andrea Knight2, Laura Trupin3, Patricia P. Katz3 and Edward H. Yelin4, 1Pediatrics/Rheumatology, UC San Francisco, San Francisco, CA, 2Pediatrics/Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, 3Medicine/Rheumatology, University of California San Francisco, San Francisco, CA, 4Medicine/Rheumatology, UC San Francisco, San Francisco, CA

    Background/Purpose: Neuropsychiatric syndromes are prevalent in childhood-onset systemic lupus erythematosus (cSLE), but the long-term risk of depression in adults with cSLE is unknown. We compared…
  • Abstract Number: 396 • 2015 ACR/ARHP Annual Meeting

    A Comparison of the Illness Experience Reported Via the Patient Reported Outcomes Measurement Information System Between Patients with Childhood-Onset Systemic Lupus Erythematosus, Juvenile Idiopathic Arthritis, and Widespread Chronic Musculoskeletal Pain

    Michael J. Holland1, Jordan Jones1, Esi M. Morgan DeWitt2, Susmita Kashikar-Zuck3, David D. Sherry4, Adam C. Carle5, Bin Huang6, Constance Mara7 and Hermine I. Brunner1, 1Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 3Behavioral Medicine & Clinical Psychology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 4Pediatric Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, 5University of Cincinnati Department of Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 6Biostatistics and Epidemiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 7James M. Anderson Center for Health Systems Excellence, Cincinnati Children's Hospital Medical Center, Cincinnati, OH

    Background/Purpose: The Patient Reported Outcomes Measurement Information System (PROMIS¨), developed by the National Institutes of Health, seeks to create standardized instruments to measure patient reported…
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