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  • Abstract Number: 1467 • 2016 ACR/ARHP Annual Meeting

    Cardiovascular Risk Assessment in Persons with Rheumatoid Arthritis: Non-Invasive Arterial Health Testing to Assess Subclinical Risk of Cardiovascular Disease

    Erin Scanlon1, Rekha Mankad2, Cynthia S. Crowson3, Iftikhar Kullo4, Sharon Mulvagh2, Eric L. Matteson1, Zoran Kvrgic1 and John M. Davis III5, 1Rheumatology, Mayo Clinic, Rochester, MN, 2Cardiovascular Diseases, Mayo Clinic, Rochester, MN, 3Health Sciences Research, Mayo Clinic, Rochester, MN, 4Department of Internal Medicine, Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN, 5Division of Rheumatology, Mayo Clinic, Rochester, MN

    Background/Purpose:   Measures of arterial health may be useful in assessing the risk of atherosclerotic cardiovascular disease (ASCVD) in patients with rheumatoid arthritis (RA). The…
  • Abstract Number: 1468 • 2016 ACR/ARHP Annual Meeting

    Increased Mitral and Tricuspid Valve Regurgitation Among Mexican Mestizo Patients with Rheumatoid Arthritis

    Dionicio A. Galarza-Delgado1, Jose Ramon Azpiri-Lopez2, Iris J. Colunga-Pedraza1, Rosa I. Arvizu-Rivera3, Adrian Martinez-Moreno4, Luis E. Gonzalez-Carrillo4, Miguel A. Ramos-Guzman4, Filiberto Hervert-Cavazos4, Alberto Cardenas-de La Garza1, Raymundo Vera-Pineda5, Mario Alberto Garza-Elizondo1 and Mario Alberto Benavides-González4, 1Rheumatology, Hospital Universitario, UANL., Monterrey, Mexico, 2Cardiology, Hospital Universitario, UANL., Monterrey, Mexico, 3Rheumatology, Hospital Universitario UANL, Monterrey, Mexico, 4Cardiology, Hospital Universitario UANL, Monterrey, Mexico, 5Cardiology., Hospital Universitario, UANL., Monterrey, Mexico

    Background/Purpose: Rheumatoid arthritis (RA) is chronic, systemic, inflammatory, multifactorial disease that mainly affects synovial joints. RA-patients have an increased risk of cardiovascular (CV) morbidity and…
  • Abstract Number: 1469 • 2016 ACR/ARHP Annual Meeting

    Coronary Territories Are Not Affected in Mexican Mestizo Patients with Rheumatoid Arthritis in Comparison to Matched Controls: Evaluation Using Speckle Tracking Echocardiography

    Dionicio A. Galarza-Delgado1, Iris J. Colunga-Pedraza2,3,4, Jose Ramon Azpiri-Lopez5, Adrian Martinez-Moreno6, Rosa I. Arvizu-Rivera2, Raymundo Vera-Pineda7, Alberto Cardenas-de La Garza3, Mario Alberto Garza-Elizondo8, Mario Alberto Benavides-González6, Miguel A. Ramos-Guzman6, Luis E. Gonzalez-Carrillo6 and Filiberto Hervert-Cavazos6, 1Internal Medicine/Rheumatology, Hospital Universitario UANL, Monterrey, Mexico, 2Rheumatology, Hospital Universitario UANL, Monterrey, Mexico, 3Rheumatology, Hospital Universitario, UANL., Monterrey, Mexico, 4Departamento de Medicina Interna del Hospital Universitario “Dr. José Eleuterio González”, Universidad Autónoma de Nuevo León, Servicio de Reumatología, Departamento de Medicina Interna del Hospital Universitario “Dr. José Eleuterio González”, Universidad Autónoma de Nuevo León, Monterrey, Mexico, 5Cardiology, Hospital Universitario, UANL., Monterrey, Mexico, 6Cardiology, Hospital Universitario UANL, Monterrey, Mexico, 7Cardiology., Hospital Universitario, UANL., Monterrey, Mexico, 8Rheumatology, Hospital Universitario UANL., Monterrey, N.L., Mexico

    Background/Purpose:  Atherosclerotic cardiovascular disease is the leading cause of death in patients with rheumatoid arthritis (RA). Two dimensional speckle tracking echocardiography (TSE) assess local and…
  • Abstract Number: 1470 • 2016 ACR/ARHP Annual Meeting

    Moderate to Severe Disease Activity in Rheumatoid Arthritis  Is Associated with Myocardial  18f-Fluorodeoxyglucose (18F-FDG) Uptake

    Isabelle Amigues1, Jon T. Giles2, Afshin Zartoshti3, Rachelle Morgenstern4, Raul Flores5, Sabahat Bokhari6 and Joan Bathon7, 1Division of Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY, 2Rheumatology, Columbia University Medical Center, NY, NY, 3Rheumatology, Columbia University, College of Physicians & Surgeons, New York city, NY, 4Cardiology, columbia university college of physicians and surgeons, New York city, NY, 5Medicine, Columbia University, New York Presbyterian, New York city, NY, 6Cardiology, Columbia University College of Physicians & Surgeons, NY, NY, 7Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY

    Background/Purpose: RA patients are at increased risk for developing heart failure (HF) even after controlling for coronary artery disease (CAD), indicating that factors other than…
  • Abstract Number: 1471 • 2016 ACR/ARHP Annual Meeting

    Myocardial 18f-Fluorodeoxyglucose (18F-FDG) Uptake in RA Patients without Clinical Cardiovascular Disease Is Higher Than in Controls and Decreases with Treatment

    Isabelle Amigues1, Jon T. Giles2, Afshin Zartoshti3, Rachelle Morgenstern4, Raul Flores5, Sabahat Bokhari6 and Joan Bathon7, 1Division of Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY, 2Rheumatology, Columbia University Medical Center, NY, NY, 3Rheumatology, Columbia University, College of Physicians & Surgeons, New York city, NY, 4Cardiology, columbia university college of physicians and surgeons, New York city, NY, 5Medicine, Columbia University, New York Presbyterian, New York city, NY, 6Cardiology, Columbia University College of Physicians & Surgeons, NY, NY, 7Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY

    Background/Purpose:   Symptomatic heart failure (HF) and HF-associated mortality rates are higher in RA compared with the non-RA population, even after controlling for coronary artery…
  • Abstract Number: 1472 • 2016 ACR/ARHP Annual Meeting

    Comparison Between Carotid Plaque and Carotid Intima-Media Thickness to Detect Subclinical Atherosclerosis in Rheumatoid Arthritis

    Lucia C. Domínguez-Casas1, Leyre Riancho-Zarrabeitia1, Nuria Vegas-Revenga2, Alfonso Corrales1, Carlos Fernández Díaz1, Montserrat Santos-Gómez3, Virginia Portilla2, Patrick H Dessein4, Ricardo Blanco1 and Miguel Angel Gonzalez-Gay1, 1Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, 2Hospital Universitario Marqués de Valdecilla. IDIVAL, Santander, Spain, 3Rheumatology, Hospital Can Misses, Ibiza, Spain, 4Cardiovascular Pathophysiology and Genomics Research Unit, School of Physiology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa

    Background/Purpose:   Carotid plaque (CP) detected by ultrasonography and carotid intima-media thickness (cIMT) are useful surrogate markers for subclinical atherosclerosis and good predictors of cardiovascular…
  • Abstract Number: 1473 • 2016 ACR/ARHP Annual Meeting

    Expression of Vitamin D Receptor Associated Genes in the Aorta of Coronary Artery Disease Patients with and without Rheumatoid Arthritis

    Ingvild Oma1, Sverre Holm2,3, Jacqueline Kirsti Andersen4, Ole K. Olstad5, Ida G. Fostad6, Torstein Lyberg5, Sven Martin Almdahl7, Øyvind Molberg8 and Ivana Hollan9,10,11, 1Innlandet Hospital Trust, Lillehammer, Norway, 2Research Institute for Internal Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway, 3Lillehammer Hospital for Rheumatic Diseases, Lillehammer, Norway, 4Norwegian University of Science and Technology, Gjøvik, Norway, 5Department of Medical Biochemistry, Oslo University Hospital, Oslo, Norway, 6Department of Oral Biology, Faculty of Dentistry, University of Oslo, Oslo, Norway, 7Department of Cardiothoracic Surgery, University Hospital of North Norway, Tromsø, Norway, 8Oslo University Hospital, Oslo, Norway, 9Brigham and Women’s Hospital, Boston, MA, 10Harvard Medical School, Boston, MA, 11Lillehammer Hospital for Rheumatic Diseases, Lillahammer, Norway

    Background/Purpose: Vitamin D has an important role in the immune system, and has been linked to inflammation, rheumatoid arthritis (RA) and coronary artery disease (CAD)[1,…
  • Abstract Number: 1474 • 2016 ACR/ARHP Annual Meeting

    Increased Levels of Lipoprotein(a) in RA Patients with Cardiovascular Disease

    Sverre Holm1,2, Ingvild Oma3, Tor-Arne Hagve4, Kjell Saatvedt5, Knut Mikkelsen6, Hans Rydningen7, Sven Martin Almdahl8, Pål Aukrust9,10, Bente Halvorsen9,11 and Ivana Hollan6,12,13,14, 1Hospital For Rheumatic Diseases, Lillehammer, Norway, 2Research Institute for Internal Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway, 3Innlandet Hospital Trust, Lillehammer, Norway, 4Oslo University Hospital, Rikshospitalet, Oslo, Norway, 5Department of Cardiothoracic Surgery, Oslo University Hospital, Oslo, Norway, 6Lillehammer Hospital for Rheumatic Diseases, Lillehammer, Norway, 7Feiring Heart Clinic, Feiring, Norway, 8Department of Cardiothoracic Surgery, University Hospital of North Norway, Tromsø, Norway, 9Institute of Clinical Medicine, University of Oslo, Oslo, Norway, 10Research Intitute for Internal Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway, 11Research Institute of Internal Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway, 12Department of Medicine, Brigham and Women’s Hospital, Boston, MA, 13Harvard Medical School, Boston, MA, 14Department of Medicine, Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Patients with various inflammatory rheumatic diseases (IRD) have increased cardiovascular morbidity caused by atherosclerosis. The aetiology of the accelerated atherosclerosis in IRD is still…
  • Abstract Number: 1475 • 2016 ACR/ARHP Annual Meeting

    Comparative Risk of Cardiovascular Outcomes Between Topical and Oral Non-Selective Nsaids in Taiwanese Rheumatoid Arthritis Patients

    Tzu-Chieh Lin1, Daniel H. Solomon2, Sara K. Tedeschi1, Kazuki Yoshida3 and Yea-Huei Kao Yang4, 1Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 2Division of Rheumatology, Brigham and Women's Hospital, Boston, MA, Boston, MA, 3Department of Epidemiology, Harvard School of Public Health, Boston, MA, 4College of Medicine, National Cheng Kung University, Institute of Clinical Pharmacy and Pharmaceutical Science, Taian, Taiwan

    Background/Purpose: Topical NSAIDs (tNSAIDs) have less systemic absorption than oral NSAIDs (oNSAIDs).  Thus, tNSAIDs may be associated with a reduced cardiovascular disease (CVD) risk compared…
  • Abstract Number: 1476 • 2016 ACR/ARHP Annual Meeting

    Diastolic Dysfunction in Patients with Rheumatoid Arthritis: Predictors of Longitudinal Progression over Five Years

    John M. Davis III1, Grace Lin2, Jae Oh3, Sara J. Achenbach4, Terry M. Therneau5, Eric L. Matteson6, Elena Myasoedova6, Sherine E. Gabriel7 and Cynthia S. Crowson8, 1Division of Rheumatology, Mayo Clinic, Rochester, MN, 2General Internal Medicine, University of California San Francisco, San Francisco, CA, 3ICON Late Phase and Outcomes Research, San Francisco, CA, 4Department of Health Sciences Research, Mayo Clinic, Rochester, MN, 5Biostatistics, Mayo Clinic, Rochester, MN, 6Rheumatology, Mayo Clinic, Rochester, MN, 7Dean's Office, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, 8Health Sciences Research, Mayo Clinic, Rochester, MN

    Background/Purpose:   The impairment of left ventricular (LV) relaxation and passive filling, known as diastolic dysfunction, undergirds the development of heart failure in patients with…
  • Abstract Number: 1477 • 2016 ACR/ARHP Annual Meeting

    Exploring the Inadequate Cardiovascular Disease Prevention in Inflammatory Joint Diseases: Results from a Nationwide Norwegian Project

    Eirik Ikdahl1, Silvia Rollefstad2, Grunde Wibetoe3, Anne Salberg4, Dag Magnar Soldal5, Inge C Olsen6, Tore K Kvien7, Anne Grete Semb1 and Glenn Haugeberg8, 1Preventive Cardio-Rheuma clinic, Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 2Preventive Cardio-Rheuma Clinic, Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 3Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 4Hospital for Rheumatic Diseases, Lillehammer, Norway, 5Rheumatology, Hospital of Southern Norway, Kristiansand, Norway, 6Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 7Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 8Martina Hansens Hospital, Bærum, Norway

    Background/Purpose: Antihypertensives (antiHT) and lipid lowering therapies (LLT) prevent cardiovascular disease (CVD) effectively. It has been reported that patients with rheumatoid arthritis (RA) receive suboptimal…
  • Abstract Number: 1478 • 2016 ACR/ARHP Annual Meeting

    Coronary Artery Calcification in Rheumatoid Arthritis Patients Is Not Characterized By an Increase in Genes Associated with Coronary Artery Disease in the General Population

    Ivan Ferraz-Amaro1, Robert Winchester2, Peter K. Gregersen3, Richard J. Reynolds4, Annette M. Oeser5, Cecilia P. Chung6, C. Michael Stein6, Mary Chester M. Wasko7, Jon T. Giles8 and Joan Bathon2, 1Rheumatology Division, Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain, 2Rheumatology, Columbia University, College of Physicians & Surgeons, New York, NY, 3Robert S. Boas Center for Genomics and Human Genetics, Feinstein Institute for Med Res, Manhasset, NY, 4Medicine, University of Alabama at Birmingham, Birmingham, AL, 5Vanderbilt University Medical Center, Nashville, TN, 6Medicine, Vanderbilt University Medical Center, Nashville, TN, 7Lupus Center, Pittsburgh, PA, 8Rheumatology, Columbia University Medical Center, NY, NY

    Background/Purpose: In the general population individuals with coronary artery disease (CAD) have a significantly increased frequency of particular susceptibility single nucleotide polymorphisms (SNPs). Since CAD…
  • Abstract Number: 1479 • 2016 ACR/ARHP Annual Meeting

    Cardiovascular Diseases and Mortality Are Independently Influenced By Carotid Plaque Presence in Rheumatoid Arthritis: The 5-Year Prospective Study

    Jung Su Eun1, Eun Song Lee2, Jong Wan Kang1, Na Ri Kim1, Ji Hun Kim1, Jin Young Kang1, Eon Jeong Nam3 and Young Mo Kang1, 1Division of Rheumatology, Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea, The Republic of, 2Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea, The Republic of, 3Division of Rheumatology, Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, South Korea

    Background/Purpose:  Patients with rheumatoid arthritis (RA) have a higher risk of cardiovascular disease (CVD) and premature mortality, compared to the general population. Inflammatory burden and conventional…
  • Abstract Number: 1480 • 2016 ACR/ARHP Annual Meeting

    Determination of the Lipid Profile in Active Disease Leads to Incorrect Cardiovascular Risk Prediction in Early Rheumatoid Arthritis Patients

    Samina A. Turk1, Dirkjan van Schaardenburg1,2, Willem F. Lems1,3 and Mike T. Nurmohamed1,3, 1Rheumatology, Amsterdam Rheumatology and immunology Center, location Reade, Amsterdam, Netherlands, Amsterdam, Netherlands, 2Rheumatology, Amsterdam Rheumatology and immunology Center, location Academic Medical Center, Amsterdam, Netherlands, Amsterdam, Netherlands, 3Rheumatology, Amsterdam Rheumatology and immunology Center, VU University medical center, Amsterdam, Netherlands

    Background/Purpose: Rheumatoid arthritis (RA) is associated with increased cardiovascular morbidity and mortality. This cardiovascular risk is mainly determined by the lipid profile, which may change…
  • Abstract Number: 1481 • 2016 ACR/ARHP Annual Meeting

    Success Rate of Blood Pressure Goal Achievement in Patients with Inflammatory Joint Diseases

    Silvia Rollefstad, Pia Norheim, Eirik Ikdahl and Anne Grete Semb, Preventive Cardio-Rheuma clinic, Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway

    Background/Purpose: The excess risk of cardiovascular disease (CVD) in patients with inflammatory joint diseases (IJD) is attributable to several risk factors, including a high prevalence…
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