Abstracts Archive - Page 1697 of 2425 - ACR Meeting Abstracts

Abstract Number: 109 • 2015 ACR/ARHP Annual Meeting
Association of HLA-G and Leukocyte Immunoglobulin-like Receptor A3 Polymorphisms with the Susceptibility to Pulmonary Hyterpention in Systemic Sclerosis
Yuki Hachiya¹, Aya Kawasaki¹, Takashi Matsushita², Hiroshi Furukawa¹, Shouhei Nagaoka³, Kota Shimada⁴, Shoji Sugii⁴, Keigo Setoguchi⁵, Akira Okamoto⁶, Noriyuki Chiba⁷, Eiichi Suematsu⁸, Masao Katayama⁹, Shunsei Hirohata¹⁰, Hajime Kono¹¹, Kiyoshi Migita¹², Takayuki Sumida¹³, Shigeto Tohma¹⁴, Minoru Hasegawa¹⁵, Manabu Fujimoto¹⁶, Shinichi Sato¹⁷, Kazuhiko Takehara¹⁸ and Naoyuki Tsuchiya¹⁹, ¹Molecular and Genetic Epidemiology Laboratory, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan, ²Department of Dermatology, Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa city, Japan, ³Rheumatology, Yokohama Minami Kyosai Hospital, Yokohama, Japan, ⁴Department of Rheumatic Diseases, Tokyo Metropolitan Tama Medical Center, Fuchu, Japan, ⁵Department of Allergy and Immunological Diseases, Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital, Tokyo, Japan, ⁶Department of Rheumatology,, Himeji Medical Center, National Hospital Organization, Himeji, Japan, ⁷Department of Rheumatology, Morioka National Hospital, NHO, Iwate, Japan, ⁸Department of Internal Medicine and Rheumatology, National Hospital Organization, Kyushu Medical Research Center, Fukuoka, Japan, ⁹Division of Rheumatology, Department of Internal Medicine, Nagoya Medical Center, National Hospital Organization, Nagoya City, Aichi, Japan, ¹⁰Rheumatology and Infectious Diseases, Kitasato University School of Medicine, Kanagawa, Japan, ¹¹Department of Internal Medicine, Teikyo University, Tokyo, Japan, ¹²Department of Rheumatology and Clinical Research Center, Nagasaki Medical Center, Omura, Japan, ¹³Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan, ¹⁴Sagamihara Hospital, National Hospital Organization, Sagamihara, Japan, ¹⁵Dermatology, Faculty of Medical Sciences, University of Fukui, Fukui, Japan, ¹⁶Department of Dermatology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan, ¹⁷Dermatology, University of Tokyo Graduate School of Medicine, Tokyo, Japan, ¹⁸Dermatology, Department of Dermatology, Faculty of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa city, Japan, ¹⁹Faculty of Medicine, University of Tsukuba, Tsukuba, Japan
Background/Purpose: Human leukocyte antigen-G (HLA-G) is a non-classical class I molecule expressed in the immune cells, the spleen, and the lungs, and plays a key…
Abstract Number: 110 • 2015 ACR/ARHP Annual Meeting
Genome-Wide DNA Epigenetic Profiling of Monozygotic Twins[L1] Discordant for ACPA or ACPA-Positive Rheumatoid Arthritis Reveals Novel Associated Genes
David Gomez¹, Malin Almgren², Louise Sjoholm², Aase Haj Hensvold³, Andrew Feinberg⁴, L. Klareskog⁵, Tomas Ekstrom^2,6 and Anca I Catrina⁵, ¹Unit of Computational Medicine Karolinska Institutet Center for Molecular Medicine Karolinska University Hospital, stockholm, Sweden, ²Laboratory for Medical Epigenetics, Dept. of Clinical Neuroscience, Karolinska Institutet, Karolinska Hospital, Stockholm, Sweden, ³Rheumatology Unit, Department of Medicine, Solna, Karolinska Institute, Stockholm, Sweden, Stockholm, Sweden, ⁴Department of Genetics, Johns Hopkins University School of Medicine, Baltimore, MD, ⁵Rheumatology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden, ⁶Departmen of Clinical Neuroscience, karolinska Institute, Stockholm, Sweden
Background/Purpose: Occurrence and progression of complex autoimmune diseases are orchestrated by interactions between genes and environment, in part mediated by epigenetic mechanisms. It is yet…
Abstract Number: 111 • 2015 ACR/ARHP Annual Meeting
The Mitochondrial DNA (mtDNA) Haplogroups Influence the Risk of Radiographic OA Progression. a Meta-Analysis
Angel Soto-Hermida¹, Ignacio Rego-Pérez¹, Juan Fernandez-Tajes¹, Mercedes Fernandez Moreno¹, Maria Eugenia Vazquez Mosquera¹, Estefanía Cortés-Pereira¹, Sara Relaño-Fernandez¹, Sonia Pertega², Natividad Oreiro¹, Carlos Fernandez-Lopez¹ and Francisco J. Blanco¹, ¹Servicio de Reumatología. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC), A Coruña, Spain, ²Unidad de Epidemiología Clínica y Bioestadística. Instituto de Investigación Biomédica de A Coruña (INIBIC). Complexo Hospitalario Universitario de A Coruña (CHUAC), Sergas. Universidade da Coruña (UDC), A Coruña, Spain
Background/Purpose: In the last years the role played by the mtDNA haplogroups in the pathogenesis of OA attracted much attention. The aim of this study…
Abstract Number: 112 • 2015 ACR/ARHP Annual Meeting
The Molecular Genetic Analysis of the Autoinflammatory Syndromes in Russian Patients with Manifestation of Systemic Juvenile Idiopathic Arthritis
Ekaterina Alexeeva¹, Alexander Baranov², Kirill Savostyanov², Alexander Pushkov², Tatyana Sleptsova¹, Tatyana Bzarova¹, Saniya Valieva¹, Rina Denisova¹, Kseniya Isayeva¹, Evgeniya Chistyakova¹ and Chomahidze Alexandra¹, ¹Rheumatology, Scientific Center of Children's Health, Moscow, Russia, ²Scientific Center of Children's Health, Moscow, Russia
Background/Purpose: Group of monogenic autoinflammatory syndromes is characterized by recurrent episodes of fever and inflammation. Methods: The study included 90 pts (37 boys, 63 girls)…
Abstract Number: 113 • 2015 ACR/ARHP Annual Meeting
Longitudinal, Incremental Direct Medical Costs of Giant Cell Arteritis for the First Five Years Following Diagnosis: A General Population-Based Cohort Study
Natalie McCormick¹, Carlo Marra² and J Antonio Avina-Zubieta³, ¹Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada, ²Pharm Sciences, Univ of British Columbia, Vancouver, BC, Canada, ³Arthritis Research Canada / University of British Columbia, Vancouver, BC, Canada
Background/Purpose: Giant cell arteritis (GCA) is the most common form of adult vasculitis, but estimates of the healthcare costs of GCA are extremely scarce. We…
Abstract Number: 114 • 2015 ACR/ARHP Annual Meeting
Surfing the Net: Patient Empowerment or Patient Deceit? Fifteen-Year Trends on the World Wide Web Information for Patients with Rheumatoid Arthritis
Jose de Jesus Valdivia-Nuno¹, Victor Brambila-Barba¹, Luis Hernandez-Sanchez¹, Jose Juan Castaneda-Sanchez¹, Carlos Gallegos-Rios¹, Gabriel Flores-Hernandez¹, Angel Suarez-Rico¹, Zalathiel Barajas-Ochoa¹, Heber Garagarza-Mariscal¹, Andrea Ramirez-Gomez², Jose Dionisio Castillo-Ortiz² and Cesar Ramos-Remus², ¹Servicio Social, Universidad de Guadalajara, Guadalajara, Mexico, ²Unidad de Investigacion en Enfermedades Cronico-Degenerativas, Guadalajara, Mexico
Background/Purpose: Considering rheumatoid arthritis (RA) is a chronic disease that lasts for decades, patient education is of upmost importance. RA patients seeking information on the…
Abstract Number: 115 • 2015 ACR/ARHP Annual Meeting
Validation of a Large Rheumatoid Arthritis Cohort and Preventive Health Screening
Michael Grasso¹, Dana Direnzo², Yelena Yesha³, Naphtali Rishe⁴ and Amanda Niskar⁵, ¹Emergency Medicine, University of Maryland School of Medicine, Baltimore, MD, ²Internal Medicine, University of Maryland Medical Center, Baltimore, MD, ³Computer Science and Electrical Engineering, Professor, Baltimore, MD, ⁴Computer Science, Florida International University, Miami, FL, ⁵1330 West Peachtree Street NW, Arthritis Foundation, Atlanta, GA
Background/Purpose: We extracted a large cohort of rheumatoid arthritis (RA) patients, on which we plan to apply big data analytics for earlier diagnosis of RA.…
Abstract Number: 116 • 2015 ACR/ARHP Annual Meeting
The Effect of the Formal Approval of Colchicine on Utilization of Emergency Department and Rheumatology Outpatient Services By Patients with Gout
Leah Krull^1,2, Erin Patton^3,4 and Harry D. Fischer^5,6, ¹Internal Medicine, Mount Sinai Beth Israel, New York, NY, ²Medicine, Mount Sinai Icahn School of Medicine, New York, NY, ³Rheumatology, Mount Sinai Icahn School of Medicine, New York, NY, ⁴Medicine/Rheumatology, Mount Sinai Beth Israel, New York, NY, ⁵Division of Rheumatology, Mount Sinai Beth Israel, New York, NY, ⁶Medicine/Rheumatology, Mount Sinai Icahn School of Medicine, New York, NY
Background/Purpose: Although colchicine has been used in the management of gout for decades, it had never undergone the formal approval process by the Food and…
Abstract Number: 117 • 2015 ACR/ARHP Annual Meeting
Same Day Rheumatology Access Clinic in an Academic Health Care Center
Muhammad Ijaz^1,2, Alireza Meysami¹, Amita Bishnoi¹ and Bernard Rubin³, ¹Rheumatology, Henry Ford Hospital, Detroit, MI, ²Rheumatology, Wayne State University/Detroit Medical Center, Detroit, MI, ³Rheumatology, Henry Ford Health System, Detroit, MI
Background/Purpose: Open access clinics have been studied extensively in the primary care setting 1, but there is limited data regarding rheumatology open access clinics. To…
Abstract Number: 118 • 2015 ACR/ARHP Annual Meeting
Identifying the Investment Needed to Generate a Durable Prednisone Dose Decrement
Martha Delgado¹, Lorena Wilson², James D. Katz³ and Ann Biehl⁴, ¹the National Institute of Arthritis Musculoskeletal and Skin Diseases, the National Institutes of Health, Bethesda, MD, ²National Institute of Arthritis and Musculoskeletal and Skin Diseases, The National Institutes of Health, Bethesda, MD, ³Department of Medicine, Division of Rheumatology, The George Washington University, Washington, DC, ⁴Department of Pharmacy, National Institutes of Health Clinical Center, Bethesda, MD
Background/Purpose: Assessment of the total cost of care requires clinical, epidemiological, patient-centered, and economic data. However, barriers to a value-driven outcome assessment include the resource-intensive…
Abstract Number: 119 • 2015 ACR/ARHP Annual Meeting
Triage in Chronic Rheumatic Diseases: Quantitative Physician Estimates for Inflammation (Reversible), Damage (Irreversible), and Distress in Patients with Rheumatoid Arthritis, Osteoarthritis, and Fibromyalgia Seen in Usual Care
Isabel Castrejón¹, Kathryn A. Gibson², Ruchi Jain¹, Annie Huang¹, Joel A. Block³ and Theodore Pincus¹, ¹Rheumatology, Rush University Medical Center, Chicago, IL, ²Liverpool Hospital, Liverpool, Australia, ³Rush University Medical Center, Chicago, IL
Background/Purpose: A physician estimate of a patient’s global status (DOCGL) often is most often the most efficient of all 7 rheumatoid arthritis (RA) core data…
Abstract Number: 120 • 2015 ACR/ARHP Annual Meeting
Validity of the Inpatient Diagnosis of Systemic Lupus Erythematosus: Clarifying Hospital Readmission Rates
Sadiq Ali¹, Stephen Mullis², Amer Al-Khoudari¹ and Dennis Ang¹, ¹Section on Rheumatology and Immunology, Wake Forest University, Winston Salem, NC, ²Department of Internal Medicine, Wake Forest University, Winston Salem, NC
Background/Purpose: Systemic lupus erythematosus (SLE) is assumed to be associated with one of the highest hospital readmission rates among chronic illnesses. Based on a recently…
Abstract Number: 121 • 2015 ACR/ARHP Annual Meeting
Serum Uric Acid Levels and Gout Flares in a US Managed Care Setting
Aki Shiozawa¹, Erin Buysman², Stephanie Korrer² and Hyon Choi³, ¹Global Outcomes and Epidemiology Research, Takeda Pharmaceuticals International, Inc, Deerfield, IL, ²Health Economics and Outcomes Research, Optum, Eden Prairie, MN, ³Massachussetts General Hospital/Harvard Medical School, Boston, MA
Background/Purpose: Gout is a common chronic inflammatory condition due to hyperuricemia. Gout patients typically have the clinical manifestation of acute painful flare attacks. While the…
Abstract Number: 122 • 2015 ACR/ARHP Annual Meeting
General Practitioners’ Perceptions of Methotrexate and Anti-TNF Therapies: A Qualitative Study
Martin Soubrier¹, Sylvain Mathieu² and Elise Berthet³, ¹Rheumatology department CHU Clermont-Ferrand, Clermont-Ferrand, France, ²Rheumatology Department, CHU clermont-Ferrand, Clermont-Ferrand, France, ³Rheumatology, CHU Gabriel Montpied, Clermont-Ferrand, France
Background/Purpose: Remission of disease is the primary goal in chronic inflammatory arthritis, especially in rheumatoid arthritis. Traditional disease-modifying drugs like methotrexate and anti-tumor necrosis factor…
Abstract Number: 123 • 2015 ACR/ARHP Annual Meeting
An Economic Evaluation of Tofacitinib (Xeljanz) Treatment in Rheumatoid Arthritis: Modeling the Cost of Treatment Strategies in the US
Lindsay Claxton¹, Matthew Taylor¹, Michelle Jenks¹, Gene Wallenstein², Alan Mendelsohn³, Jeffrey Bourret³, Amitabh Singh³ and Robert Gerber², ¹York Health Economics Consortium, University of York, York, United Kingdom, ²Pfizer Inc, Groton, CT, ³Pfizer Inc, Collegeville, PA
Background/Purpose: Tofacitinib is an oral Janus kinase (JAK) inhibitor for the treatment of rheumatoid arthritis (RA). An economic model was developed to evaluate the treatment…

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