Abstracts Archive - Page 1635 of 2425 - ACR Meeting Abstracts

Abstract Number: 15L • 2015 ACR/ARHP Annual Meeting
Identification of Four-and-a-Half-LIM Domain 1 (FHL1) As a New Autoantibody Target in Idiopathic Inflammatory Myopathies
Inka Albrecht¹, Cecilia Wick¹, Åsa Hallgren², Anna Tjärnlund¹, Kanneboyina Nagaraju³, Felipe Andrade⁴, Kathryn Thompson⁵, William Coley⁵, Aditi Phadke⁶, Lina-Marcela Diaz-Gallo¹, Matteo Bottai⁷, Inger Nennesmo⁸, Karine Chemin⁹, Jessica Herrath¹⁰, Karin Johansson¹, Anders Wikberg¹, Jimmy Ytterberg¹, Roman Zubarev¹, Olof Danielsson¹¹, Olga Krystufkova¹², Jiri Vencovsky¹³, Nils Landegren², Marie Wahren-Herlenius¹⁴, Leonid Padyukov¹⁵, Olle Kämpe² and Ingrid E. Lundberg¹⁶, ¹Rheumatology Unit, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden, ²Experimental Endocrinology, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden, ³The George Washington University Medical Center, Children's National Medical Center, Washington, DC, ⁴Division of Rheumatology, The Johns Hopkins University School of Medicine, Baltimore, MD, ⁵Children's National Medical Center, Washington, DC, ⁶Research Center for Genetic Medicine, Children's National Medical Center, Washington, DC, ⁷Institute for Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, ⁸Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden, ⁹Medicine, Rheumatology Unit, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden, ¹⁰Department of Medicine,, Rheumatology Unit, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden, ¹¹Department of Clinical and Experimental Medicine, Division of Neurology, Faculty of Health Sciences, Linköping University, Linköping, Sweden, ¹²Institute of Rheumatology and Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, ¹³Rheumatology, Institute of Rheumatology and Department of Rheumatology, 1st Faculty of Medicine, Charles University, Prague, Czech Republic, ¹⁴Department of Medicine, Experimental Rheumatology Unit, Solna, Sweden, ¹⁵Department of medicine, Rheumatology Unit, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden, ¹⁶Karolinska University Hospital, Rheumatology Unit, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden
Background/Purpose: Idiopathic inflammatory myopathies (IIMs) are a heterogeneous group of rare systemic autoimmune diseases collectively called myositis causing progressive muscle weakness. Interestingly, myositis-specific autoantibodies described…
Abstract Number: 2445 • 2015 ACR/ARHP Annual Meeting
Development and Usability Testing of an Ipad-Based Psycho-Educational Game for Children with Juvenile Idiopathic Arthritis and Their Parents
Jennifer N. Stinson¹, Adam M. Huber², Mark Connelly³, Nadia Luca⁴, Lynn R. Spiegel⁵, Argerie Tsimicalis⁶, Stephanie Luca⁷, Roberta Berard⁸, Julie Barsalou⁹, Sarah Campillo¹⁰, Paul Dancey¹¹, Ciarán M. Duffy¹², Brian Feldman¹³, Nicole Johnson⁴, Patrick McGrath¹⁴, Natalie J. Shiff¹⁵, Shirley M Tse¹⁶, Lori B. Tucker¹⁷ and J. Charles Victor¹⁸, ¹Anesthesia and Pain Medicine, The Hospital for Sick Children, Toronto, ON, Canada, ²Pediatric rheumatology, IWK Health Centre, Halifax, NS, Canada, ³Psychology, University of Kansas Medical Center, Kansas City, KS, ⁴Pediatrics/Alberta Children's Hospital, Department of Pediatrics/University of Calgary, Calgary, AB, Canada, ⁵Rheumatology/Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada, ⁶McGill University, Montreal, QC, Canada, ⁷The Hospital for Sick Children, Toronto, ON, Canada, ⁸Children's Hospital of Western Ontario, London, ON, Canada, ⁹CHU Sainte-Justine, Université de Montréal, Montreal, QC, Canada, ¹⁰Rheumatology, Montreal Children's Hospital, Montreal, QC, Canada, ¹¹Health Science Centre, Memorial University of Newfoundland, St Johns, NF, Canada, ¹²Children's Hospital of Eastern Ontario and University of Ottawa, Ottawa, ON, Canada, ¹³Division of Rheumatology, The Hospital for Sick Children and University of Toronto, Toronto, ON, Canada, ¹⁴IWK Health Centre, Halifax, NS, Canada, ¹⁵Pediatric Rheumatology, University of Saskatchewan, Saskatoon, SK, Canada, ¹⁶Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ¹⁷Rheumatology, BC Children's Hospital, Vancouver, BC, Canada, ¹⁸University of Toronto, Toronto, ON, Canada
Background/Purpose: Juvenile Idiopathic Arthritis (JIA) is a common chronic childhood illness that can negatively impact health-related quality of life (HRQL). In younger years, children manage…
Abstract Number: 2446 • 2015 ACR/ARHP Annual Meeting
Synovial Fluid Proteins Differentiate Patients with Oligoarticular Juvenile Idiopathic Arthritis Who Are Destined to Extend from Those Who Will Remain Persistent in Course
AnneMarie C. Brescia¹, Megan M. Simonds², Kathleen E. Sullivan³ and Carlos D. Rose⁴, ¹Pediatric Rheumatology, Nemours A.I. duPont Hospital for Children, Wilmington, DE, ²Nemours Research, Nemours/AI duPont Hospital for Children, Wilmington, DE, ³Allergy Immunology, The Children's Hospital of Philadelphia, Philadelphia, PA, ⁴Pediatrics, Nemours A.I. duPont Hospital for Children, Division of Pediatric Rheumatology, Thomas Jefferson University, Wilmington, DE
Background/Purpose: Children with oligoarticular juvenile idiopathic arthritis (JIA) who have an extended course (recruitment of 5 or more joints after 6 months of disease) have…
Abstract Number: 2447 • 2015 ACR/ARHP Annual Meeting
The Juvenile Arthritis Disease Activity Score Remains the Disease Activity Marker of Choice for Adults with Polyarticular Juvenile Idiopathic Arthritis
Qiong Wu¹, Nicola Ambrose^1,2,3, Debajit Sen^1,2,3, Maria J. Leandro⁴, Charlotte Wing², Nicola Daly², Kate Webb^1,2, Corinne Fisher^1,2, Linda Suffield¹, Francesca Josephs¹, Clarissa Pilkington³, Despina Eleftheriou^1,3, Muthana Al-Obaidi³, Sandrine Compeyrot-Lacassagne³, Lucy R Wedderburn^1,3 and Yiannis Ioannou^1,2,3, ¹Arthritis Research UK Centre for Adolescent Rheumatology, University College London, London, United Kingdom, ²Adolescent Rheumatology Department, University College London Hospital NHS Trust, London, United Kingdom, ³Paediatric Rheumatology Department, Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom, ⁴Centre for Rheumatology and Bloomsbury Rheumatology Unit, University College London, London, United Kingdom
Background/Purpose: A considerable proportion of children with polyarticular juvenile idiopathic arthritis (polyJIA) continue to experience active disease into adulthood. There is no validated disease activity…
Abstract Number: 2448 • 2015 ACR/ARHP Annual Meeting
Flare Definitions for Juvenile Idiopathic Arthritis (JIA) Based on ACR Core Set Variables and Patient Reported Outcomes: Results from the Research in Arthritis in Canadian Children-Emphasizing Outcomes Prospective Cohort
Vinay Shivamurthy¹, Deborah M. Levy², Gilles Boire³, Karen N Watanabe Duffy⁴, Elizabeth Stringer⁵, Rosie Scuccimarri⁶, Rae S.M. Yeung⁷, Adam M. Huber⁸, Kiem Oen⁹, Natalie Shiff¹⁰, Lori B. Tucker¹¹, Roberta Berard¹², Kimberly Morishita¹³, Ciarán M. Duffy¹⁴ and Jaime Guzman¹⁵, ¹Pediatrics/Rheumatology, British Columbia Children's Hospital, Vancouver, BC, Canada, ²Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ³Department of Medicine/Division of Rheumatology, Université de Sherbrooke, Sherbrooke, QC, Canada, ⁴Rheumatology, Children's Hospital of Eastern Ontario and University of Ottawa, Ottawa, ON, Canada, ⁵Department of Rheumatology, IWK Health Centre, Halifax, NS, Canada, ⁶Pediatrics, McGill University, Montréal, QC, Canada, ⁷Pediatrics, Immunology and Medical Science, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada, ⁸Pediatric rheumatology, IWK Health Centre, Halifax, NS, Canada, ⁹University of Manitoba, Winnipeg, MB, Canada, ¹⁰Pediatric Rheumatology, University of Saskatchewan, Saskatoon, SK, Canada, ¹¹Rheumatology, BC Children's Hospital, Vancouver, BC, Canada, ¹²Children's Hospital of Western Ontario, London, ON, Canada, ¹³Pediatric Rheumatology, BC's Children's Hospital, Vancouver, BC, Canada, ¹⁴Children's Hospital of Eastern Ontario and University of Ottawa, Ottawa, ON, Canada, ¹⁵Rheumatology, Division of Rheumatology, BC Children's Hospital, Vancouver, BC, Canada
Background/Purpose: A valid flare definition is needed in clinical practice to identify a clinically relevant worsening which will guide us make treatment decisions. While the…
Abstract Number: 2449 • 2015 ACR/ARHP Annual Meeting
Does Antinuclear Antibodies Predict Remission in JIA ?
Mia Glerup¹, Troels Herlin² and Marinka Twilt³, ¹Pediatrics, Aarhus University Hospital, Skejby, Aarhus, Denmark, ²Department of Pediatrics, Århus University Hospital Skejby, Århus, Denmark, ³Rheumatology, Alberta Children's Hospital, Calgary, AB, Canada
Background/Purpose: In the recent years the classification of Juvenile Idiopathic Arthritis (JIA) according to the ILAR criteria has been questioned as some categories still include…
Abstract Number: 2450 • 2015 ACR/ARHP Annual Meeting
Examination of the Clinical Significance of 14-3-3 Eta in Juvenile Idiopathic Arthritis
Lance Feller¹, Austin M. Dalrymple², Paul Tuttle IV³, Reema H. Syed³, Peri Pepmueller¹ and Terry Moore⁴, ¹Rheumatology, Saint Louis University, St. Louis, MO, ²Pediatric Rheumatology, St. Louis University, St. Louis, MO, ³IM-Rheumatology, Saint Louis University, St. Louis, MO, ⁴Division of Rheumatology and Pediatric Rheumatology, Saint Louis University School of Medicine, St Louis, MO
Background/Purpose: 14-3-3 proteins are chaperonins found in all eukaryotic cells. There are multiple isoforms which are thought to be involved in intracellular signaling and transcription…
Abstract Number: 2451 • 2015 ACR/ARHP Annual Meeting
Scoring Medication Requirements and Side-Effects in Juvenile Idiopathic Arthritis: Perspectives of Patients, Parents and Clinicians
Lori B. Tucker¹, Natalie Shiff², Susanne Benseler³, Roberta Berard⁴, Roman Jurencak⁵, Thomas Loughin⁶, Jaime Guzman⁷ and Andrew Henrey⁶, ¹Rheumatology, BC Children's Hospital, Vancouver, BC, Canada, ²Pediatric Rheumatology, University of Saskatchewan, Saskatoon, SK, Canada, ³Pediatrics, University of Calgary, Toronto, ON, Canada, ⁴Children's Hospital of Western Ontario, London, ON, Canada, ⁵University of Ottawa, Ottawa, ON, Canada, ⁶Statistics and Actuarial Science, Simon Fraser University, Burnaby, BC, Canada, ⁷Rheumatology, Division of Rheumatology, BC Children's Hospital, Vancouver, BC, Canada
Background/Purpose: Medication requirements (MedReq) and medication side effects (MedSE) were found to be top priorities by patients, parents and clinicians in describing the course of…
Abstract Number: 2452 • 2015 ACR/ARHP Annual Meeting
Clinical and Functional Outcomes in Patients with Polyarticular Juvenile Idiopathic Arthritis Following Treatment with Adalimumab
Daniel J. Kingsbury¹, Pierre Quartier², G Horneff³, Kirsten Minden⁴, Mary Toth⁵, Nupun A. Varothai⁶, Anabela Cardoso⁷ and Jasmina Kalabic⁶, ¹Randall Children's Hospital at Legacy Emanuel, Portland, OR, ²Hopital Necker-Enfants Malades, Paris, France, ³Asklepios Klinik Sankt Augustin, Sankt Augustin, Germany, ⁴Kinderklinik der Charite, Otto-Heubner Centrum, Berlin, Germany, ⁵Akron Children's Hospital, Akron, OH, ⁶AbbVie, North Chicago, IL, ⁷AbbVie, Amadora, Portugal
Background/Purpose: The Juvenile Arthritis Disease Activity Score (JADAS) is increasingly accepted for defining a treat-to-target strategy in patients (pts) with juvenile idiopathic arthritis (JIA)1 The…
Abstract Number: 2453 • 2015 ACR/ARHP Annual Meeting
Evidence-Based Decision Support for Pediatric Rheumatology Reduces Diagnostic Errors, with the Potential to Reduce Capacity Shortage
Balu Athreya¹, Mary Beth Son², Jonathan S. Hausmann³, Elizabeth Ang⁴, David Zurakowski⁵, Michael Segal⁶ and Robert Sundel⁷, ¹duPont Hospital for Children/Thomas Jefferson University, Wilmington, DE, ²Division of Immunology, Children's Hospital Boston, Boston, MA, ³Rheumatology, Children's Hospital Boston, Boston, MA, ⁴Paediatrics, University Children's Medical Institute, NUH, Singapore, Singapore, ⁵Departments of Anesthesia and Surgery, Boston Children’s Hospital, Boston, MA, ⁶SimulConsult, Chestnut Hill, MA, ⁷Immunology, Childrens Hospital, Boston, MA
Background/Purpose: This projects seeks to respond to the critical shortage of pediatric rheumatologists encapsulating the diagnostic information of the field in an advanced diagnostic decision…
Abstract Number: 2454 • 2015 ACR/ARHP Annual Meeting
Target and Targetoid Reactions at Bacillus Calmettee-Guérin Inoculation Site Revealed By Dermatoscopy Correlate with Systemic Involvements in Patients with Kawasaki Disease
Kuo Ho-Chang and Kawasaki Disease Center, Pediatrics, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan
Background/Purpose: For the past decades, the rash at the Bacillus Calmettee-Guérin (BCG) inoculation sites has been recognized as a useful diagnostic clue in Kawasaki disease…
Abstract Number: 2455 • 2015 ACR/ARHP Annual Meeting
Utilization and Education of Nurse Practitioners in Pediatric Rheumatology
Sandra Mintz¹, Karla B. Jones² and Andreas Reiff³, ¹4650 Sunset Boulevard, Mailstop 60, Children's Hospital of LA, Los Angeles, CA, ²Rheumatology, Nationwide Children's, Columbus, OH, ³Childrens Hosp LA MS60, Los Angeles, CA
Background/Purpose: Due to the shortage of subspecialty physicians there is an increasing need of adding mid-level practitioners to specialty practices (Solomon, Bitton, et.al., 2014). However…
Abstract Number: 2456 • 2015 ACR/ARHP Annual Meeting
Anti SRP+Ve Myositis in Childhood. Presentation and Physiotherapy Treatment of This Rare Childhood Myositis
Susan Maillard and Clarissa Pilkington, Paediatric Rheumatology, Great Ormond Street Hospital NHS Foundation Trust for Children, London, United Kingdom
Background/Purpose: Previously it was understood that all Myositis in childhood was Juvenile Dermatomyositis. More recently Myositis specific antibodies have been discovered and these appear to…
Abstract Number: 2457 • 2015 ACR/ARHP Annual Meeting
Physical Function and Psychological Well-Being in Teens with Juvenile Idiopathic Arthritis (JIA): Characterization and Exploration of Technology-Assisted Self-Management
Carrie Shotwell¹, Paula Melson², Jason Long³ and Tracy Ting⁴, ¹Occupational therapy and physical terapy, Cincinnati Children's Hospital Medical Center, CINCINNATI, OH, ²Rheumatology, Children's Hosp Medical Center, Cincinnati, OH, ³Orthopaedic Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁴Rheumatology/MLC 4010, Cincinnati Children's Hosp, Cincinnati, OH
Background/Purpose: This study sought to assess the physical function and psychological well- being of teens with juvenile idiopathic arthritis (JIA) as well as to assess…
Abstract Number: 2458 • 2015 ACR/ARHP Annual Meeting
Psychostimulant-Induced Vasculopathy: A Retrospective Study in a Pediatric Rheumatology Clinic
Freda Singletary¹, Nirupma Sharma¹ and Rita Jerath², ¹Pediatrics, Georgia Regents University-Children's Hospital of Georgia, Augusta, GA, ²Dept of Pediatrics, Childrens Med Ctr Med Schl GA, Augusta, GA
Background/Purpose: Attention-deficit/hyperactivity disorder (ADHD) is the most common neurobehavioral disorder of childhood. The first line treatment is psychostimulant medications namely, methylphenidate, amphetamines, or their derivatives. …

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