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  • Abstract Number: 3181 • 2016 ACR/ARHP Annual Meeting

    The Utility of Urinalysis in Determining the Risk of Renal Relapse in ANCA-Associated Vasculitis

    Rennie L. Rhee1, John C. Davis2, Linna Ding3, Fernando Fervenza4, Gary S. Hoffman5, Cees G.M. Kallenberg6, Carol A. Langford7, W Joseph McCune8, Paul A. Monach9, Philip Seo10, Robert F. Spiera11, Eugene William St.Clair12, Ulrich Specks4, John H. Stone13 and Peter A. Merkel14, 1Rheumatology, University of Pennsylvania, Philadelphia, PA, 2Baxalta, Cambridge, MA, 3NIH, Bethesda, MD, 4Mayo Clinic, Rochester, MN, 5Rheumatology, Cleveland Clinic, Cleveland, OH, 6Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, 7Rheumatic and Immunologic Diseases, Cleveland Clinic, Cleveland, OH, 8Int Med/ Rheum, University of Michigan, Ann Arbor, MI, 9Rheumatology, Boston University School of Medicine, Boston, MA, 10Medicine, Johns Hopkins University, Baltimore, MD, 11Hospital for Special Surgery, Cornell, New York, NY, 12Rheumatology and Immunology, Duke University, Durham, NC, 13Massachusetts General Hospital Rheumatology Unit, Harvard Medical School, Boston, MA, 14Division of Rheumatology, Univ of Pennsylvania; Perelman School of Med, Philadelphia, PA

       Background/Purpose: The significance of persistent hematuria or proteinuria in patients with ANCA-associated vasculitis (AAV) who are in clinical remission is still unclear. This study…
  • Abstract Number: 3182 • 2016 ACR/ARHP Annual Meeting

    Attenuation of Fluorine-18-Fluorodeoxyglucose Uptake in Large Vessel Giant Cell Arteritis after Short-Term High-Dose Steroid Treatment – a Diagnostic Window of Opportunity

    Berit Dalsgaard Nielsen1, Ib Tønder Hansen2, Kresten Krarup Keller3, Philip Therkildsen4, Ellen-Margrethe Hauge3 and Lars Christian Gormsen5, 1Rheumatology, Department of Rheumatology, Aarhus University Hospital, Århus C, Denmark, 2Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark, 3Rheumatology, Department of Rheumatology, Aarhus University Hospital, Aarhus, Denmark, 4Department of Rheumatology, Aarhus University Hospital, Aarhus C, Denmark, 5Nuclear Medicine and PET Center, Department of Nuclear Medicine and PET Center, Aarhus University Hospital, Århus C, Denmark

    Background/Purpose: Fluorine-18-fluorodeoxyglucose (18F-FDG) PET/CT is, due to its excellent diagnostic accuracy[1], increasingly used to diagnose large vessel GCA (LV-GCA). However, PET/CT is not always readily…
  • Abstract Number: 3183 • 2016 ACR/ARHP Annual Meeting

    Tocilizumab for the Treatment of Giant Cell Arteritis – MR-Angiography Results from the First Randomized Placebo-Controlled Trial 

    Stephan Reichenbach1,2, Sabine Adler3, Jennifer Cullmann4, Harald Bonel4, Stefan Kuchen5, Felix Wermelinger1, Diana Dan1, Michael Seitz1 and Peter M. Villiger1, 1Department of Rheumatology, Immunology and Allergology, University Hospital Bern, Bern, Switzerland, 2Institute of Social and Preventive Medicine, University of Bern, Bern, Switzerland, 3Rheumatology, Immunology, Allergology, University Hospital Bern, Bern, Switzerland, 4Department of Diagnostic, Interventional and Pediatric Radiology, University Hospital Bern, Bern, Switzerland, 5Rheumatology, Immunology, and Allergology, University of Bern, Bern, MD, Switzerland

    Background/Purpose:  As published in The Lancet online, March 4, 2016, the first randomized, placebo-controlled trial (RCT) of tocilizumab (TCZ) in giant cell arteritis (GCA) showed…
  • Abstract Number: 3184 • 2016 ACR/ARHP Annual Meeting

    Antiphospoholipid Antibodies in Giant Cell Arteritis. What Can They Tell Us?

    Alojzija Hocevar, Rok Jese, Ziga Rotar, Polona Žigon, Sašša Čučnik and Matija Tomšič, Department of Rheumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia

    Background/Purpose: The aim of our prospective study was to evaluate the potential impact of the antiphospholipid antibodies (aPL-Abs) on the clinical presentation of giant cell…
  • Abstract Number: 3185 • 2016 ACR/ARHP Annual Meeting

    Sensitivity Analysis for the Smoking Paradox in the Development of Psoriatic Arthritis Among Psoriasis Patients

    Uyen-Sa D.T. Nguyen1,2, Yuqing Zhang2, David T. Felson2,3,4, Michael P. Lavalley5 and Hyon K. Choi6, 1Orthopedics and Physical Rehabilitation, University of Massachusetts Medical School, Worcester, MA, 2Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, 3Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, 4Arthritis Research UK Centre for Epidemiology, Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom, 5Biostatistics, Boston University School of Public Health, Boston, MA, 6Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: Smoking is a strong risk factor for psoriasis and psoriatic arthritis, but several studies have found that smoking is inversely associated with the risk…
  • Abstract Number: 3186 • 2016 ACR/ARHP Annual Meeting

    Determinants of Patient-Physician Discordance in Global Assessment in Psoriatic Arthritis and Levels of Discordance According to Disease Activity: A Multicenter European Study

    Carole Desthieux1, Benjamin Granger2, Andra Rodica Balanescu3, P Balint4, Jürgen Braun5, Juan Canete6, Turid Heiberg7, Philip S. Helliwell8, Umut Kalyoncu9, Tore K Kvien10, Uta Kiltz5, Dora Niedermayer11, Kati Otsa12, Rossana Scrivo13, Josef Smolen14, Tanja A. Stamm15, Douglas J. Veale16, Kurt de Vlam17, Maarten de Wit18 and Laure Gossec1, 1Rheumatology, Pitié Salpêtrière Hospital, Paris, France, 2Biostatistics, Pitié Salpêtrière Hospital, Paris, France, 3Department of Internal Medicine and Rheumatology “Sf. Maria” Hospital, Bucharest, Romania, 4Rheumatology, National Institute of Rheumatology and Physiotherapy, Budapest, Hungary, 5Rheumazentrum Ruhrgebiet, Herne, Germany, 6Rheumatology, Hospital Clínic and IDIBAPS, Barcelona, Spain, 7Oslo University Hospital, Oslo, Norway, 8NIHR-Leeds Musculoskeletal Biomedical Research Unit, Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 9Hacettepe University, Ankara, Turkey, 10Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, 11PsAID taskforce, EULAR, Zurich, Switzerland, 12Rheumatology, Tallinn Central Hospital, Tallinn, EE, 13Department of Internal Medicine and Medical Specialties, Sapienza University, Rome, Italy, 14Medical University of Vienna and Hietzing Hospital, Vienna, Austria, 15Internal Medicine III, Vienna Medical University, Vienna, Austria, 16Consultant Rheumatologist, Centre for Arthritis and Rheumatic Disease, St. Vincent’s University Hospital and University College Dublin, Dublin 4, Ireland, 17Katholieke Universiteit Leuven, Leuven, Belgium, 18Medical Humanities, VU Medical Centre, Amsterdam, Netherlands

    Background/Purpose: In the management of chronic diseases, recommendations insist on the need to work in partnership with the patient. Patient-physician discordance in global assessment of…
  • Abstract Number: 3187 • 2016 ACR/ARHP Annual Meeting

    Societal Costs and Patients’ Experience of Health Inequities from Psoriatic Arthritis: A Danish Cohort Study

    Lars Erik Kristensen1, Tanja S Jørgensen2, Robin Christensen3, Henrik Gudbergsen4, Lene Dreyer5, Christine Ballegaard6, Lennart T.H. Jacobsson7, Vibeke Strand8, Philip J Mease9 and Jakob Kjellberg10, 1Musculoskeletal Statistics Unit, The Parker Institute, Dept. of Rheumatology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark, 2The Parker Institute, Copenhagen, Denmark, 3Musculoskeletal Statistics Unit, The Parker Institute, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Copenhagen, Denmark, 4Knowledge Centre for Telemedicine and Departments of Rheumatology, Copenhagen University Hospitals, Glostrup, Frederiksberg and Bispebjerg, Frederiksberg, Denmark, 5Internal Medicine - Rheumatology Section, Copenhagen University Hospital at Gentofte, Copenhagen, Denmark, 6The Parker institute, Copenhagen, Denmark, 7Department of Rheumatology and Inflammation Research, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden, 8Stanford University School of Medicine, Palo Alto, CA, 9University of Leeds, Leeds, United Kingdom, 10Danish Institute for Local and Regional Government Research, Copenhagen, Denmark, Copenhagen, Denmark

    Background/Purpose: Psoriatic arthritis (PsA), a chronic inflammatory joint disorder typically affecting individuals with psoriasis of the skin, is associated with severe comorbidities, reduced quality of…
  • Abstract Number: 3188 • 2016 ACR/ARHP Annual Meeting

    Association of Gout with Risk of Advanced Chronic Kidney Disease

    Austin Stack1, Betina Blak2, Michelle Johnson3, Victoria Parsons3, Andrew Maguire4, Alyssa B Klein5, John Ferguson6 and Robert Morlock7, 1Nephrology, University Hospital Limerick & Health Research Institute,University of Limerick, Limerick, Ireland, 2AstraZeneca,, Luton, United Kingdom, 3Oxon Epidemiology Ltd, London, United Kingdom, 4Epidemiology, Oxon Epidemiology Ltd, London, United Kingdom, 5AstraZeneca, Gaithersburg, MD, 6Graduate Entry Medical School, University of Limerick, Limerick, Ireland, 7Ardea Biosciences, Inc., San Diego, CA

    Background/Purpose: It is speculated that gout is a risk factor for kidney disease progression. The aim of this study was to evaluate the association of…
  • Abstract Number: 3189 • 2016 ACR/ARHP Annual Meeting

    Patient Perceptions of Glucocorticoid Side Effects: A Survey of Users in an Online Health Community

    Ruth Costello1, Rikesh Patel1, Jennifer Humphreys1, John McBeth1 and William G Dixon2, 1Manchester Academic Health Science Centre, Arthritis Research UK Centre for Epidemiology, The University of Manchester, Manchester, United Kingdom, 2Manchester Academic Health Sciences Centre, Arthritis Research UK Centre for Epidemiology, The University of Manchester, Manchester, United Kingdom

    Background/Purpose: Glucocorticoids (GC) are widely used to treat inflammatory diseases, but are known to have many side effects. Patients’ perspectives of side effects are known…
  • Abstract Number: 3190 • 2016 ACR/ARHP Annual Meeting

    Epidemiology of Polymyalgia Rheumatica 2000-2014: A Population Based Study

    Shafay Raheel1, Cynthia S. Crowson2 and Eric L. Matteson1, 1Rheumatology, Mayo Clinic, Rochester, MN, 2Health Sciences Research, Mayo Clinic, Rochester, MN

    Background/Purpose: To determine time trends in the incidence and survival analysis of polymyalgia rheumatica (PMR) over a 15 year period in a geographically defined population…
  • Abstract Number: 3191 • 2016 ACR/ARHP Annual Meeting

    Coronary Revascularization Procedure Rates and Risks Among Patients with Systemic Lupus Erythematosus Compared to Those with Diabetes Mellitus in a Nationwide Medicaid Cohort

    Medha Barbhaiya1, Candace H. Feldman1, Sarah K. Chen2, Hongshu Guan3, Tzu-Chieh Lin1, Michael A. Fischer4, Daniel H. Solomon5, Brendan M. Everett6 and Karen H. Costenbader1, 1Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 2Beth Israel Deaconess Medical Center, Boston, MA, 3Rheumatology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 4Division of Pharmacoepidemiology and Pharmacoeconomics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 5Division of Rheumatology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 6Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA

    Background/Purpose : We have recently found that myocardial infarction (MI) risk was similar among age- and sex-matched SLE patients compared to diabetes mellitus (DM) patients…
  • Abstract Number: 3192 • 2016 ACR/ARHP Annual Meeting

    Influence of Temperature and Humidity on Disease Activity in Rheumatoid Arthritis

    Peter Mandl1, Farideh Alasti1, Rainer Kaltenberger2, Thomas Krennert2, Gabriela Supp1, Uriel Landesmann1, Josef S. Smolen3 and Daniel Aletaha4, 1Department of Internal Medicine III; Division of Rheumatology, Medical University Vienna, Vienna, Austria, 2Central Institute for Meteorology and Geodynamics, Vienna, Austria, 3Department of Internal Medicine 3, Division of Rheumatology, Medical University of Vienna, Vienna, Austria, 4Department of Internal Medicine 3, Medical University of Vienna, Vienna, Austria

    Background/Purpose: To evaluate whether meteorological parameters influence pain and disease activity in patients with rheumatoid arthritis (RA). Methods: We assessed correlations between individual meteorological variables…
  • Abstract Number: 3193 • 2016 ACR/ARHP Annual Meeting

    Is an Intensive Diet and Exercise Regimen Cost-Effective for Obese and Overweight Patients with Symptomatic Knee OA?

    Elena Losina1, Karen C. Smith2, A. David Paltiel3, Lisa Gale Suter4, Jeffrey N. Katz5 and Stephen P. Messier6, 1Orthopedics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 2Orthopaedics, Brigham and Women's Hospital, Boston, MA, 3Yale University, New Haven, CT, 4Medicine, Rheumatology, Yale University, New Haven, CT, 5Orthopaedics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 6Department of Health and Exerc, Wake Forest University, Winston-Salem, NC

    Background/Purpose: About 50% of persons with knee OA are obese. Quality-adjusted life-year losses due to knee OA and obesity exceed 3.5 per person. The results…
  • Abstract Number: 3194 • 2016 ACR/ARHP Annual Meeting

    Factors Related to Physicians’ Prescriptions for Rheumatoid Arthritis Drugs Never Filled or Subsequently Discontinued By Patients

    Hong J. Kan1, Kirill Dyagilev1, Peter Schulam2, Suchi Saria1, Charles Molta3 and Jeffrey Curtis4, 1John Hopkins University, Baltimore, MD, 2Department of Computer Science, Johns Hopkins University, Baltimore, MD, 3Sun Pharmaceutical, Cranbury, NJ, 4Division Clinical Immunology & Rheumatology, University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose:  Rheumatologists have many choices of medications to use for patients with rheumatoid arthritis (RA), but patients may not fill a prescription (primary non-adherence or…
  • Abstract Number: 3195 • 2016 ACR/ARHP Annual Meeting

    Patterns and Predictors of Hydroxychloroquine Nonadherence in a Nationwide Cohort of Medicaid Beneficiaries with Systemic Lupus Erythematosus

    Candace H. Feldman1, Jamie E. Collins2, Zhi Zhang3, Daniel H. Solomon4, Karen H. Costenbader1 and Ichiro Kawachi5, 1Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 2Orthopaedic and Arthritis Center for Outcomes Research, Department of Orthopedic Surgery, Brigham & Women's Hospital, Boston, MA, 3Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, 4Brigham and Women’s Hospital and Harvard Medical School, Boston, MA, 5Social and Behavioral Sciences, Harvard T. H. Chan School of Public Health, Boston, MA

    Background/Purpose: Hydroxychloroquine (HCQ) is the standard of care medication for most SLE patients, however cross-sectional studies suggest that nonadherence is common. Similar to the fluctuating…
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