Abstracts Archive - Page 1619 of 2607 - ACR Meeting Abstracts

Abstract Number: 290 • 2016 ACR/ARHP Annual Meeting
Viscosupplemenation Efficacy in Knee Oa Is Similar in Single-Injection Vs. Multi-Week Formulations and Across OA Severity and BMI Subgroups, but Better in Younger Patients
Thayer Mukherjee¹, Fernando Bomfim², Evan Wilder¹, Lauren Browne², Shira Aharon³, Kayleigh Toth¹, Eric Strauss⁴ and Jonathan Samuels⁵, ¹NYU Langone Medical Center, New York, NY, ²Rheumatology, NYU Langone Medical Center, New York, NY, ³NYU Langone Medical Center, Rheumatology, New York, NY, ⁴Orthopedic Surgery, NYU Langone Medical Center, New York, NY, ⁵Division of Rheumatology, Department of Medicine, NYU Langone Medical Center, New York, NY
Background/Purpose: Hyaluronic acid (HA) viscosupplementation is widely used in patients with knee osteoarthritis (KOA), but variable reported outcomes have impacted its incorporation into treatment algorithms.…
Abstract Number: 291 • 2016 ACR/ARHP Annual Meeting
Relation of Foot Pronation during Walking to Risk of Worsening Lateral Patellofemoral and Medial Tibiofemoral Cartilage Damage
K. Douglas Gross^1,2, Howard J. Hillstrom³, Carrie Brown⁴, Richard Jones⁵, Joshua Stefanik⁶, Michael C. Nevitt⁷, Cora E. Lewis⁸, James Torner⁹ and David T. Felson², ¹Physical Therapy, MGH Institute of Health Professions, Boston, MA, ²Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, ³Rehabilitation, Hospital Special Surgery (HSS), New York, NY, ⁴Boston University School of Public Health, Boston, MA, ⁵School of Health Sciences, University of Salford, Manchester, United Kingdom, ⁶Physical Therapy, Northeastern University, Boston, MA, ⁷Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, ⁸Preventive Medicine, University of Alabama at Birmingham, Birmingham City, AL, ⁹Epidemiology, University of Iowa, Iowa City, Iowa City, IA
Background/Purpose: Foot pronation can lead to lateral patellofemoral (PF) maltracking with reduced tibiofemoral (TF) varum, inciting speculation that the highly pronated foot reported in knees…
Abstract Number: 292 • 2016 ACR/ARHP Annual Meeting
Knee Osteoarthritis and the Risk of Fall Injuries Among Older Adults: The Health ABC Study
Kamil E. Barbour¹, Robert M. Boudreau², Naoko Sagawa³, Jane A. Cauley⁴, Michael C. Nevitt⁵, Tomoko Fujii⁶, Kushang Patel⁷ and Elsa S. Strotmeyer², ¹Arthritis Program, Centers for Disease Control and Prevention, Atlanta, GA, ²Epidemiology, University of Pittsburgh, Pittsburgh, PA, ³Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA, USA, Pittsburgh, PA, ⁴Department of Epidemiology, Univ of Pittsburgh, Pittsburgh, PA, ⁵Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, ⁶University of Pittsburgh, Pittsburgh, PA, ⁷Center for Pain Research on Impact, Measurement & Effectiveness, Department of Anesthesiology & Pain Medicine, University of Washington, Seattle, WA
Background/Purpose: Falls are the leading cause of injury-related morbidity and mortality in older adults. To our knowledge no studies have examined the association between knee…
Abstract Number: 293 • 2016 ACR/ARHP Annual Meeting
A Systematic Review and Network Meta-Analysis of Long-Term Trials of Pharmacological Treatments in Knee Osteoarthritis
Dario Gregori¹, Giampaolo Giacovelli², Clara Minto¹, Beatrice Barbetta², Francesca Gualtieri², Danila Azzolina¹, Paola Vaghi² and Lucio C. Rovati^2,3, ¹Unit of Biostatistics, Epidemiology and Public Health, Department of Cardiac, Thoracic and Vascular Sciences, University of Padova, Padova, Italy, ²Clinical Research Department, Rottapharm Biotech, Monza, Italy, ³University of Milano Bicocca, Milano, Italy
Background/Purpose: Osteoarthritis (OA) is a chronic and progressive degenerative disease. While management of OA should be directed to long-term control of symptoms and joint structure…
Abstract Number: 294 • 2016 ACR/ARHP Annual Meeting
Serum Urate Levels Predict Joint Space Narrowing in Non-Gout Patients with Medial Knee Osteoarthritis
Charles Oshinsky¹, Mukundan Attur², Sisi Ma³, Hua Zhou³, Fangfei Zheng¹, Meng Chen⁴, Jyoti Patel², Jonathan Samuels⁵, Virginia Pike⁶, Ravinder Regatte⁷, Jenny Bencardino⁸, Leon Rybak⁹, Steven B. Abramson¹⁰, Michael H. Pillinger¹¹ and Svetlana Krasnokutsky Samuels¹², ¹Medicine/Rheumatology, NYU School of Medicine, NEW YORK, NY, ²Rheumatology Research, NYU - Hospital for Joint Diseases, New York, NY, ³Bioinformatics, New York University, New York, NY, ⁴NYU School of Medicine, NEW YORK, NY, ⁵Division of Rheumatology, Department of Medicine, NYU Langone Medical Center, New York, NY, ⁶Medicine/Rheumatology, NYU School of Medicine/NYU Hospital for Joint Diseases, New York, NY, ⁷NYU Department of Radiology, NEW YORK, NY, ⁸Radiology, NYU Langone Medical Center, New York, NY, ⁹Department of Radiology, NYU Langone Medical Center, New York, NY, ¹⁰Dept of Rheumatology/Medicine, Hosp for Joint Diseases/NYU, New York, NY, ¹¹NYU School of Medicine, New York, NY, ¹²NYU School of Medicine, Division of Rheumatology, New York, NY
Background/Purpose: Osteoarthritis (OA) etiopathogenesis includes an inflammatory component. Published reports indicate that synovial fluid urate levels, even in patients without gout, associate with OA prevalence/severity.…
Abstract Number: 295 • 2016 ACR/ARHP Annual Meeting
Efficacy and Safety of Fasinumab for Osteoarthritic Pain in Patients with Moderate to Severe Osteoarthritis of the Knees or Hips
Jennifer Maloney¹, Alan Kivitz², Thomas J. Schnitzer³, Paula Dakin¹, Catherine Stehman-Breen¹ and Greg Geba¹, ¹Regeneron Pharmaceuticals, Inc., Tarrytown, NY, ²Altoona Center for Clinical Research, Duncansville, PA, ³Northwestern University, Chicago, IL
Background/Purpose: Osteoarthritis (OA) is an important cause of chronic pain in older adults. Fasinumab is a fully-human, high-affinity monoclonal antibody directed against the nerve growth…
Abstract Number: 296 • 2016 ACR/ARHP Annual Meeting
Knee Osteoarthritis As Risk for Hip Osteoarthritis
Chan Kim¹, Shanshan Sheehy², Cara Lewis³, Mary M Clancy^4,5,6, Michael C. Nevitt⁷, James Torner⁸, Cora E. Lewis⁹, Ali Guermazi¹⁰ and David T. Felson¹¹, ¹Rheumatology and Clinical Epidemiology, Boston University School of Medicine, Boston, MA, ²Clinical Epidemiology Research & Training Unit, Boston University, Boston, MA, ³Physical Therapy and Athletic Training, Boston University, Boston, MA, ⁴Clinical Epidemiology, BUSM, Boston, MA, ⁵Clinical Epidemiology, Boston University School Medical, Boston, MA, ⁶Clinical Epidemiology, Boston University Sch Med, Boston, MA, ⁷Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, ⁸University of Iowa, UIowa, Iowa City, IA, ⁹University of Alabama Birmingham, Birmingham, AL, ¹⁰Boston University School of Medicine, Boston, MA, ¹¹Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA
Knee osteoarthritis as risk factor for hip osteoarthritis Background/Purpose: While the hip and knee are linked biomechanically, the risk of hip osteoarthritis (OA) in persons…
Abstract Number: 297 • 2016 ACR/ARHP Annual Meeting
Genetic and Environmental Correlation of Osteoarthritis at the Hands, Knees, and Spine
Michelle S. Yau^1,2, Yanhua Zhou³, Douglas P. Kiel⁴, Elizabeth J. Samelson¹ and David T. Felson^2,5, ¹Institute for Aging Research, Hebrew SeniorLife, Harvard Medical School, Boston, MA, ²Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, ³Department of Biostatistics, Boston University School of Public Health, Boston, MA, ⁴Institute for Aging Research, Institute for Aging Research, Hebrew Senior Life, Harvard Medical School, Boston, MA, USA, Boston, MA, ⁵Arthritis Research UK Centre for Epidemiology, Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom
Background/Purpose: Osteoarthritis (OA) may affect multiple joint sites, including the hands, knees, and spine. Studies have suggested high heritability for hand OA, but OA in the…
Abstract Number: 298 • 2016 ACR/ARHP Annual Meeting
Disease Progression in Osteoarthritis Is Driven By Multiple Disease Parameters Leading to Comparable Levels of Joint Destruction
Anne C. Bay-Jensen¹, Asger Bihlet², Inger Byrjalsen², Jeppe Andersen³, Christian S. Thudium⁴, Bente J. Riis², Claus Christiansen², Hans Guehring⁵, Martin Michaelis⁵, Christoph Ladel⁵ and Morten Asser Karsdal⁶, ¹Rheumatology, Nordic Bioscience, Biomarkers and Research, Herlev, Denmark, ²Nordic Bioscience, Clinical Development, Herlev, Denmark, ³Clinical Development, Nordic Bioscience, Herlev, Denmark, ⁴Biomarkers and Research, Nordic Bioscience, Herlev, Denmark, ⁵Merck KGaA, Darmstadt, Germany, ⁶Rheumatology, Nordic Bioscience, Herlev, Denmark
Background/Purpose: There is a need for successful drug development in osteoarthritis (OA) as there are currently no disease modifying drugs approved for OA. This may…
Abstract Number: 299 • 2016 ACR/ARHP Annual Meeting
Minimally Important Differences for Four Patient-Reported Outcomes Measurement Information System (PROMIS) Short Forms: Physical Function, Pain Interference, Depression, and Anxiety Among Adults with Knee Osteoarthritis
Augustine Lee¹, Lori Lyn Price², Jeffrey Driban³, William F. Harvey¹, Timothy E. McAlindon⁴, Angie Mae Rodday⁵ and Chenchen Wang¹, ¹Rheumatology, Tufts Medical Center, Boston, MA, ²Clinical Care Research, Tufts Medical Center, Boston, MA, ³Tufts Medical Center, Boston, MA, ⁴Division of Rheumatology, Tufts Medical Center, Boston, MA, ⁵Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA
Background/Purpose: Patient-Reported Outcomes Measurement Information System (PROMIS) provides reliable, valid measures of health status to resolve many challenges with comparability and interpretability in OA.…
Abstract Number: 300 • 2016 ACR/ARHP Annual Meeting
Mindfulness Predicts Treatment Response from Non-Pharmacological Therapy in Knee Osteoarthritis
Augustine Lee¹, Lori Lyn Price², Xingyi Han³, Mei Chung⁴, William F. Harvey¹, Jeffrey Driban⁵, Timothy E. McAlindon⁶ and Chenchen Wang¹, ¹Rheumatology, Tufts Medical Center, Boston, MA, ²Clinical Care Research, Tufts Medical Center, Boston, MA, ³Public Health and Community Medicine, Tufts University, Boston, MA, ⁴Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, ⁵Tufts Medical Center, Boston, MA, ⁶Division of Rheumatology, Tufts Medical Center, Boston, MA
Background/Purpose: Mindfulness is the ability to maintain a heightened awareness of one's moment-to-moment experiences without judging or reacting. Recent evidence suggests that mindfulness may improve…
Abstract Number: 301 • 2016 ACR/ARHP Annual Meeting
Predictive Factors for Response to Ultrasound-Guided Intra-Articular Glucocorticoids in Knee Osteoarthritis
Samy Slimani¹, Amel Aissoug², Souhila Aouidane³, Hocine Bounecer¹, Hachemi Makhloufi¹ and Aïcha Ladjouz Rezig⁴, ¹Department of Medicine, University of Batna, Batna, Algeria, ²Private practice office of rheumatology, Batna, Algeria, ³Public Health, University Hospital of Batna, Batna, Algeria, ⁴Department of Medicine, University of Algiers 1, Algiers, Algeria
Background/Purpose: To investigate predictive factors for good outcome of ultrasound intra-articular glucocorticoids in knee osteoarthritis (OA). Methods: We conducted a prospective monocenter cohort study including…
Abstract Number: 302 • 2016 ACR/ARHP Annual Meeting
Long-Lasting Local Knee Structural Pathology Is Associated with Persistent Multi-Site Pain
Feng Pan¹, Jing Tian², Dawn Aitken³, Flavia M Cicuttini⁴, Changhai Ding³ and Graeme Jones³, ¹Musculoskeletal Unit, Menzies Institute for Medical Research, University of Tasmania, Hobart,7000, Australia, ²Public health unit, Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia, ³Musculoskeletal Unit, Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia, ⁴Monash University, Department of Epidemiology and Preventive Medicine, Melbourne, Australia
Background/Purpose: Knee pain is the most common manifestation of knee osteoarthritis (OA) and typically accompanied by pain at other sites. Knee structural pathology in MRI,…
Abstract Number: 303 • 2016 ACR/ARHP Annual Meeting
Knee Physical Exam Findings and Self-Reported Symptoms Are Associated with MRI-Detected Effusion-Synovitis Among Participants with or at Risk for Knee Osteoarthritis: Data from the Osteoarthritis Initiative (OAI)
Adam Berlinberg¹, Jordan Westra², Erin L. Ashbeck², Jaren Trost¹, Frank Roemer^3,4, Ali Guermazi⁵ and C. Kent Kwoh⁶, ¹Department of Medicine, University of Arizona, Tucson, AZ, ²The University of Arizona Arthritis Center, Tucson, AZ, ³Department of Radiology, Boston University School of Medicine, Boston, MA, ⁴Radiology, University of Erlangen, Erlangen, Germany, ⁵Boston University School of Medicine, Boston, MA, ⁶1501 N. Campbell Avenue, Room 8303, The University of Arizona Arthritis Center, Tucson, AZ
Background/Purpose: Inflammation has been implicated in the pathogenesis of KOA, but the relevance of physical exam findings and patient-reported symptoms of inflammation is unknown. Our…
Abstract Number: 304 • 2016 ACR/ARHP Annual Meeting
Gait Abnormalities Due to Hip Osteoarthritis Are Different in Men and Women
Kharma C. Foucher, Orthopedic Surgery, Rush University Medical Center, Chicago, IL
Background/Purpose: Gait mechanics are different in healthy men and women.1 It is unknown whether or not the gait changes associated with hip osteoarthritis (OA), also…

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