ACR Meeting Abstracts

ACR Meeting Abstracts

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  • Abstract Number: 101 • 2017 Pediatric Rheumatology Symposium

    Defining Active Features of Juvenile Localized Scleroderma

    Suzanne Li1, Xiaohu Li2, Elena Pope3, Katie G. Stewart4, Gloria Higgins5, C. Egla Rabinovich6, Kathleen O'Neil7, Kathleen Haines8, Ronald Laxer9, Marilynn Punaro10, Heidi Jacobe11, Knut Wittkowski12, Themba Nyirenda13, Ivan Foeldvari14 and Kathryn S. Torok15, 1Pediatrics, Joseph M Sanzari Children’s Hospital, Hackensack Meridian Health, Hackensack, NJ, 2Mathematical Sciences, Stevens Institute of Technology, Hoboken, NJ, 3Dermatology, The Hospital for Sick Children, Toronto, ON, Canada, 4Pediatric Rheumatology, Texas Scottish Rite Hospital, Dallas, TX, 5Pediatrics, Nationwide Children's Hospital, Columbus, OH, 6Pediatric Rheumatology, Duke University Medical Center, Durham, NC, 7Pediatrics, Indiana University, Indianapolis, IN, 8Joseph M Sanzari Children’s Hospital, Hackensack Meridian Health, Hackensack, NJ, 9Div of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, 10Texas Scottish Rite Hospital for Children, Dallas, TX, 11Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, TX, 12Rockefeller University, New York, NY, 13Hackensack University Medical Center, Hackensack, NJ, 14Kinder- und Jugenrheumatologie, Hamburger Zentrum Kinder-und Jugendrheumatologie, Hamburg, Germany, 15Pediatric Rheumatology, Univ of Pittsburgh Med Ctr, Pittsburgh, PA

    Background/Purpose: Juvenile localized scleroderma (jLS) is the most common form of childhood scleroderma. Because of its chronicity and association with extracutaneous involvement, children are at…
  • Abstract Number: 120 • 2017 Pediatric Rheumatology Symposium

    Use Of Thalidomide From A Tertiary Level Pediatric Rheumatology Centre In India

    Manjari Agarwal1, Abhay Shivpuri2 and Sujata Sawhney3, 1Institute of Child Health, Attending Consultant, New Delhi, India, 2Division of Pediatric Rheumatology,Institute of Child Health, Post Doctoral Fellow, New Delhi, India, 3Paediatric rheumatology, Senior Consultant, New Delhi, India

    Background/Purpose: Thalidomide is an effective agent for several pediatric rheumatic diseases: Systemic onset Juvenile idiopathic arthritis(SOJIA), Behcet's disease and recalcitrant skin disease in cSLE to…
  • Abstract Number: 147 • 2017 Pediatric Rheumatology Symposium

    Epigenetic and Transcriptomic Profiling of Primary Juvenile Idiopathic Arthritis Patient Cells: Better Understanding of Disease Pathogenesis

    Lucas Picavet1, Janneke Peeters2, Sandra Coenen3, Arjan Boltjes4, Femke van Wijk5, Paul Coffer2, Bas Vastert6 and Jorg van Loosdregt7, 1Regenerative Medicine Center Utrecht, University Medical Center Utrecht, Utrecht, Netherlands, 2Center for Molecular Medicine and Regenerative Medicine Center Utrecht, University Medical Center Utrecht, Utrecht, Netherlands, 3University Medical Center Utrecht, Utrecht, Netherlands, 4Laboratory of Translational Immunology, University Medical Center Utrecht, Utrecht, Netherlands, 5Laboratory for Translational Immunity, University Medical Center Utrecht, Utrecht, Netherlands, 6Division of Pediatric Rheumatology, University Medical Center Utrecht, Utrecht, Netherlands, 7Division of Pediatrics, University Medical Center Utrecht, Utrecht, Netherlands

    Background/Purpose: For many autoimmune diseases, including Juvenile Idiopathic Arthritis (JIA), the molecular mechanisms remain elusive. JIA can be used as a model to study autoimmune…
  • Abstract Number: 125 • 2017 Pediatric Rheumatology Symposium

    How Do Health Literacy, Numeric Competencies and Patient Activation Impact Transition Readiness in Adolescents and Young Adults with Rheumatologic Diseases?

    Samuel Lazaroff1, Mary-Kate Tompkins2, Alexa Meara3, Ellen Peters4 and Stacy P. Ardoin5, 1College of Medicine, Ohio State University, Columbus, OH, 2The Ohio State University, Columbus, OH, 3Internal Medicine/Rheumatology, The Ohio State University, Columbus, OH, 4Ohio State University, Columbus, OH, 5Pediatric & Adult Rheumatology, Ohio State University, Columbus, OH

    Background/Purpose: Transition from pediatric to adult health care is a vulnerable time during which gaps in care may negatively affect disease outcomes. Validated measures including…
  • Abstract Number: 39 • 2017 Pediatric Rheumatology Symposium

    Rheumapalooza:  A rheumatology curriculum in evolution

    Kristen Hayward1 and Helen M. Emery2, 1Pediatric Rheumatology, University of Washington & Seattle Children's Hospital, Seattle, WA, 2rheumatology, Seattle Childrens Hospital, Seattle, WA

    Background/Purpose: Rheumapalooza was implemented in 2008 as an elective course with support from an ACR/REF Clinical Scholar Educator Award.1 The course was incorporated into the…
  • Abstract Number: 143 • 2017 Pediatric Rheumatology Symposium

    Influence of Age and Sex on Collagen-Induced Arthritis

    Tracy Wilson-Gerwing1, Arash Panahifar2, David M.L. Cooper2 and Alan Rosenberg1, 1Pediatrics, University of Saskatchewan, Saskatoon, SK, Canada, 2Anatomy and Cell Biology, University of Saskatchewan, Saskatoon, SK, Canada

    Background/Purpose: Age and sex differences are found in certain subsets of juvenile idiopathic arthritis (JIA). Collagen Induced Arthritis (CIA) in rodents has utility in assessing…
  • Abstract Number: 1 • 2017 Pediatric Rheumatology Symposium

    Pediatric Rheumatology Care and Outcomes Improvement Network Demonstrates Improvement on Quality Measures for Children with Juvenile Idiopathic Arthritis

    C. April Bingham1, Jesse Pratt2, Cagri Yildirim-Toruner3, Ronald Laxer4, Beth Gottlieb5, Jennifer Weiss6, Tzielan Lee7, Sheetal S. Vora8, Jon Burnham9, Julia Harris10, Judyann C. Olson11, Murray Passo12, Michelle Batthish13, Michael Shishov14, Kerry Ferraro15, Deborah M. Levy16, Christine O'Brien17, Kristi Whitney-Mahoney17, Nancy Griffin18, Anne Paul19 and Esi Morgan20, 1Penn State Health Children's Hospital, Hershey, PA, 2Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 3Rheumatology, Nationwide Children's Hospital, Columbus, OH, 4Div of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, 5Pediatric Rheumatology, Cohen Children's Medical Center of New York, New Hyde Park, NY, 6Hackensack University Medical Center, Hackensack, NJ, 7Pediatric Rheumatology, Stanford University School of Medicine, Palo Alto, CA, 8Pediatric Rheumatology, Levine Children's Hospital, Charlotte, NC, 9Children's Hospital of Philadelphia, Philadelphia, PA, 10Children's Mercy Kansas City, Kansas City, MO, 11Ped/MACC Fund Research Ctr, Medical College of Wisconsin, Milwaukee, WI, 12Division of Rheumatology PTD, Medical University of South Carolina, Charleston, SC, 13Division of Pediatric Rheumatology, McMaster Children's Hospital, Hamilton, ON, Canada, 14Pediatric Rheumatology, Phoenix Children's Hospital, Phoenix, AZ, 15Pediatric Rheumatology Care and Outcomes Improvement Network, Cincinnati, OH, 16Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, 17The Hospital for Sick Children, Toronto, ON, Canada, 18James M. Anderson Center for Health Systems Excellence, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 19Anderson Center for Health Systems Excellence, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 20Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH

    Background/Purpose: Pediatric Rheumatology Care and Outcomes Improvement Network (PR-COIN) is a growing multi-center network organized on a learning health system model designed to improve outcomes…
  • Abstract Number: 113 • 2017 Pediatric Rheumatology Symposium

    Exploring the role of pediatric rheumatologists in the diagnosis and management of autoimmune encephalitis

    Eyal Muscal1, Heather Van Mater2, Tania Cellucci3, Dominic Co4, Jennifer Frankovich5, Marisa S. Klein-Gitelman6, Marinka Twilt7 and Susanne Benseler8, 1Immunology, Allergy and Rheumatology, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, 2Pediatrics/ Pediatric Rheumatology, Duke University Medical Center, Durham, NC, 3McMaster University, hamilton, ON, Canada, 4Pediatrics, Medical College of Wisconsin, Milwaukee, WI, 5Pediatrics, Standford University, Palo Alto, CA, 6Div of Pediatric Rheumatology/PDD PTD, Lurie Children's Hospital of Chicago/NW University, Chicago, IL, 7Paediatrics, University Of Calgary, Calgary, AB, Canada, 8Pediatric Rheumatology, University of Calgary, Alberta Children's Hospital, Calgary, AB, Canada

    Background/Purpose: Autoimmune encephalitis (AE) encompasses a spectrum of immune-mediated brain disorders that cause severe neuropsychiatric manifestations. These disorders often lead to protracted hospital stays, complex…
  • Abstract Number: 146 • 2017 Pediatric Rheumatology Symposium

    Age-Related Differences in Neuronal High Mobility Group Box-1 and Resolvin D1 Receptors in Collagen-Induced Arthritis

    Tracy Wilson-Gerwing and Alan Rosenberg, Pediatrics, University of Saskatchewan, Saskatoon, SK, Canada

    Background/Purpose: More thorough understanding of age-related molecular interactions that drive inflammation and inflammatory pain is required to help guide evidenced-based, age appropriate treatment strategies that…
  • Abstract Number: 67 • 2017 Pediatric Rheumatology Symposium

    Relapse and Remission in Children with Chronic Non-Infectious Uveitis Treated with Methotrexate and Tumor Necrosis Factor-α Inhibitors

    Courtney McCracken1, Curtis Travers1, Kirsten Jenkins2, Carolyn Drews-Botsch3, Steven Yeh4, Sampath Prahalad1,5 and Sheila Angeles-Han6,7, 1Pediatrics, Emory University School of Medicine, Atlanta, GA, 2Children's Healthcare of Atlanta, Atlanta, GA, 3Epidemiology, Emory University School of Public Health, Atlanta, GA, 4Ophthalmology, Emory University School of Medicine, Atlanta, GA, 5Pediatrics, Emory Children's Center, Atlanta, GA, 6Pediatrics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 7Pediatrics, University of Cincinnati, Cincinnati, OH

    Background/Purpose: Methotrexate (MTX) and tumor necrosis factor-α inhibitors (TNFi) are common treatments for children with chronic non-infectious uveitis (NIU). Optimal duration of treatment prior to…
  • Abstract Number: 92 • 2017 Pediatric Rheumatology Symposium

    Mycophenolate Mofetil is an Effective Induction Therapy Agent in Childhood-onset Pure Membranous Lupus Nephritis

    Maria Pereira1, Eyal Muscal2, Marietta DeGuzman3, Anna Carmela Sagcal-Gironella4 and Scott E. Wenderfer5, 1Immunology, Allergy & Rheumatology, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, 2Immunology, Allergy and Rheumatology, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, 3Pediatric Immunology, Allergy and Rheumatology, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, 4Pediatric Immunology, Allergy, and Rheumatology, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, 5Pediatrics-Renal, Baylor College of Medicine, Texas Children's Hospital, Houston, TX

    Background/Purpose: Treatment guidelines for childhood-onset class V membranous lupus nephritis (MLN) have not yet been established. The addition of mycophenolate mofetil (MMF) has shown improvement…
  • Abstract Number: 153 • 2017 Pediatric Rheumatology Symposium

    Training pediatric rheumatology fellows intra-articular injection techniques and skills using a cadaver based musculoskeletal curriculum

    Baruch Goldberg1, Amanda Brown2 and Monica Marcus3, 1Pediatric Rheumatology, Texas Children's Hospital, Houston, TX, 2Allergy, Immunology and Rheumatology, Texas Children's Hospital, houston, TX, 3Pediatric Immunology, Allergy and Rheumatology, Texas Children's Hospital, Houston, TX

    Background/Purpose:  Intra-articular injections are important to treat children with arthritis. Practice differences, comfort levels, and reimbursement can decrease fellow exposure to this skill. The purpose…
  • Abstract Number: 50 • 2017 Pediatric Rheumatology Symposium

    Tumor necrosis factor-α (TNFα) inhibitor-induced psoriasis in juvenile idiopathic arthritis (JIA) patients

    Daniel Groth1, Sivia Lapidus2, Simona Nativ2 and Maria Perez3, 1Goryeb Children's Hospital, Morristown, NJ, 2Pediatric Rheumatology, Goryeb Children's Hospital, Morristown, NJ, 3Pediatric Gastroenterology, Goryeb Children's Hospital, Morristown, NJ

    Background/Purpose: Occurrence of psoriasis while on TNFα antagonists is a paradoxical effect of agents that treat psoriasis, and is described in larger cohorts of inflammatory…
  • Abstract Number: 68 • 2017 Pediatric Rheumatology Symposium

    HLA-DRB1 in Non-Hispanic African American Children with Juvenile Idiopathic Arthritis and Chronic Anterior Uveitis

    Lai Hin Kimi Chan1, Courtney McCracken1, Kirsten Jenkins2, Steven Yeh3, Purnima Patel4, Sampath Prahalad1 and Sheila Angeles-Han5, 1Pediatrics, Emory University School of Medicine, Atlanta, GA, 2Children's Healthcare of Atlanta, Atlanta, GA, 3Ophthalmology, Emory University School of Medicine, Atlanta, GA, 4Emory University School of Medicine, Atlanta, GA, 5Department of Pediatrics, Cincinnati Children's Hospital, Cincinnati, OH

    Background/Purpose: HLA-DRB1*08, 11 and 13 are strong risk alleles for various juvenile idiopathic arthritis (JIA) subtypes. We reported that carriage of DRB1*11 and *13 increased…
  • Abstract Number: 104 • 2017 Pediatric Rheumatology Symposium

    Rituximab Treatment for Chronic Steroid-Dependent Henoch-Schonlein Purpura

    Esraa M. A. Eloseily1,2, Courtney Crayne1, Melissa L Mannion3, Saji P Azerf4, Peter Weiser1, Timothy Beukelman1, Matthew L. Stoll1, Dan Feig5, Prescott Atkinson6 and Randy Q. Cron1, 1Pediatric Rheumatology, University of Alabama at Birmingham, Birmingham, AL, 2Pediatrics, Assiut University, Assiut, Egypt, 3Pediatric rheumatology, University of Alabama at Birmingham, Birmingham, AL, 4School of medicine, Univesity of Alabama at Birmingham,, Birmingham, AL, 5Pediatric Nephrology, University of Alabama at Birmingham, Birmingham, AL, 6Pediatric Allergy and Immunology, University of Alabama at Birmingham, Birmingham, AL

    Background/Purpose: Henoch-Schonlein purpura (HSP) is a small vessel vasculitis characterized by non-thrombocytopenic purpura, abdominal pain, arthritis, and glomerulonephritis. Typically, HSP is self-limited, but more severe…
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All abstracts accepted to PRYSM are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 6:00 PM CT on March 18. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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