Abstracts Archive - Page 1586 of 2607 - ACR Meeting Abstracts

Abstract Number: 2981 • 2017 ACR/ARHP Annual Meeting
Evaluation of American College of Rheumatology Provisional Composite Response Index in Systemic Sclerosis (CRISS) in the Fasscinate Trial
Dinesh Khanna¹, Veronica J. Berrocal², Christopher Denton³, Angelika Jahreis⁴, Helen Spotswood⁵, Celia J. F. Lin⁴, Jeffrey Siegel⁶ and Daniel E. Furst⁷, ¹University of Michigan, Ann Arbor, MI, ²Div of Rheumatology, University of Michigan, Ann Arbor, MI, ³Department of Rheumatology, University College London, Royal Free Hospital, London, United Kingdom, ⁴Genentech, South San Francisco, CA, ⁵Roche Products Ltd., Welwyn Garden City, CA, United Kingdom, ⁶Roche Products Ltd., Welwyn Garden City, United Kingdom, ⁷University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA
Background/Purpose: Treatment with Interleukin-6R inhibitor, tocilizumab (TCZ), in early progressive systemic sclerosis (SSc; the faSScinate trial) resulted in consistent, but not statistically significant, improvements in…
Abstract Number: 2982 • 2017 ACR/ARHP Annual Meeting
Morbidity and Mortality of Scleroderma in African Americans
Duncan F. Moore¹, Elisabeth Kramer¹, Rami Eltaraboulsi² and Virginia D. Steen¹, ¹Division of Rheumatology, Department of Medicine, MedStar Georgetown University Hospital, Washington, DC, ²MedStar Georgetown University Hospital, Washington, DC
Background/Purpose: Retrospective cohorts have demonstrated that African Americans (AAs) with scleroderma are more likely to have severe disease and higher mortality than non-AAs. A prior…
Abstract Number: 2983 • 2017 ACR/ARHP Annual Meeting
Predictors for Disease Worsening Defined By Organ Failure in Diffuse Systemic Sclerosis: A European Scleroderma Trials and Research (EUSTAR) Analysis
Mike Oliver Becker¹, Nicole Graf², Rafael Sauter³, Yannick Allanore⁴, John Curram⁵, Christopher Denton⁶, Dinesh Khanna⁷, Marco Matucci-Cerinic⁸, Janethe Pena⁹, Janet E. Pope¹⁰ and Oliver Distler¹, ¹Department of Rheumatology, Center of Experimental Rheumatology, University Hospital Zurich, Zurich, Switzerland, ²Graf Biostatistics, Winterthur, Switzerland, ³Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom, ⁴Department of Rheumatology, Cochin Hospital, Paris Descartes University, Paris, France, ⁵Bayer Plc, Newbury, United Kingdom, ⁶Department of Rheumatology, University College London, Royal Free Hospital, London, United Kingdom, ⁷University of Michigan, Ann Arbor, MI, ⁸Dept of Medicine/Div of Rheum, University of Florence, Florence, Italy, ⁹Bayer HealthCare Pharmaceuticals Inc, Whippany, NJ, ¹⁰Department of Medicine, Division of Rheumatology, University of Western Ontario, St Joseph's Health Care, London, ON, Canada
Background/Purpose: Mortality and worsening of organ function would be desirable endpoints for clinical trials in systemic sclerosis (SSc). However, these events are relatively rare, making…
Abstract Number: 2984 • 2017 ACR/ARHP Annual Meeting
Predictive Value of a Combined Index for Weight Loss in Systemic Sclerosis
Gianluca Bagnato¹, Erika Pigatto², Alessandra Bitto¹, Carmelo Pizzino¹, Natasha Irrera¹, Giuseppina Abignano³, MIchele Hutchinson⁴, Francesco Squadrito¹, Maya H. Buch⁵, Sebastiano Gangemi¹, William Neal Roberts⁶, Antonino Saitta¹, Franco Cozzi⁷ and Francesco Del Galdo⁸, ¹University of Messina, Messina, Italy, ²University of Padova, Padova, Italy, ³Rheumatology Department of Lucania,, Rheumatology Institute of Lucania (IReL), San Carlo Hospital of Potenza and Madonna delle Grazie Hospital of Matera,, Potenza, Italy, ⁴University of Leeds, Leeds, United Kingdom, ⁵NIHR-Leeds Musculoskeletal Biomedical Research Unit, Leeds, United Kingdom, ⁶University of Louisville, Louisville, LA, ⁷Division of Rheumatology, Rheumatology Unit, Department of Medicine, University of Padova, Padova, Italy, ⁸Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom
Background/Purpose: Malnutrition and severe gastrointestinal (GI) dysfunction are the cause of mortality in 4-15% of systemic sclerosis (SSc) patients whereas overall GI involvement is observed…
Abstract Number: 2986 • 2017 ACR/ARHP Annual Meeting
Omega Polyunsaturated Fatty Acids and Systemic Lupus Erythematosus (SLE): the Michigan Lupus Epidemiology & Surveillance (MILES) Program
Prae Charoenwoodhipong¹, Suzanna Zick², Wendy Marder³, Afton L. Hassett⁴, W. Joseph McCune⁵, Caroline Gordon⁶, Siobán Harlow⁷ and Emily C. Somers³, ¹University of Michigan, Ann Arbor, MI, ²Department of Family Medicine, University of Michigan, Ann Arbor, MI, ³Internal Medicine-Rheumatology, University of Michigan, Ann Arbor, MI, ⁴Rheumatology, Emory University, Atlanta, GA, ⁵Int Med/ Rheum, University of Michigan, Ann Arbor, MI, ⁶Rheumatology Research Group, Institute of Inflammation and Ageing,, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom, ⁷Epidemiology Department- School of Public Health, Obstetrics and Gynecology- Medical School, University of Michigan, Ann Arbor, MI
Background/Purpose: Omega fatty acids have immunomodulatory properties; omega-3 (n-3) fatty acids are generally anti-inflammatory and omega-6 (n-6) pro-inflammatory. High n-6:n-3 ratios (up to 16:1) are…
Abstract Number: 2987 • 2017 ACR/ARHP Annual Meeting
Moderate and Serious Psychological Distress Among US Adults with and without Arthritis, 2002 to 2015
Louise Murphy¹, Michael Boring², Teresa J. Brady³, Kristina Theis⁴, Jennifer M. Hootman⁵, Kamil E. Barbour³ and Charles G. Helmick⁴, ¹Division of Population Health, Centers for Disease Control and Prevention, Atlanta, GA, ²Cutting Edge Technology and Solutions, Mesa, AZ, ³Arthritis Program, Centers for Disease Control and Prevention, Atlanta, GA, ⁴Centers for Disease Control and Prevention, Atlanta, GA, ⁵Centers for Disease Control and Prevention, Kennesaw, GA
Background/Purpose: US population-health surveys frequently measure current mental health status using the Kessler-6 (K-6) which indicates psychological distress level. Among all US adults, moderate and…
Abstract Number: 2988 • 2017 ACR/ARHP Annual Meeting
Characteristics of People with Work-Related Versus Non-Work Related Carpal Tunnel Syndrome: National Health Interview Survey, 2010 & 2015
Nancy A. Baker, Department of Occupational Therapy, University of Pittsburgh, Pittsburgh, PA
Background/Purpose: The underlying causes of carpal tunnel syndrome (CTS) are complex and may be unrelated to work status. Yet, too often, CTS is viewed and…
Abstract Number: 2989 • 2017 ACR/ARHP Annual Meeting
Hydration and Gout: Looking at New Modes of Uric Acid Management
Patricia Kachur¹, Chirag Bambhroliya², Hong Liang³ and Pramil Cheriyath², ¹Internal Medicine, Ocala Regional Medical Center, Ocala, FL, ²Ocala Regional Medical Center, Ocala, FL, ³North Florida Regional Medical Center, Gainsville, FL
Background/Purpose: Gout affects more than 4% of adults in the United States, and it is the most common form of inflammatory arthritis among men. Studies…
Abstract Number: 2990 • 2017 ACR/ARHP Annual Meeting
Is Risk of Retinopathy Among Hydroxychloroquine Users of SLE Patients Accurate? a Simulation Study Accounting for Competing Risk of Death
Na Lu¹, Hyon K. Choi², April Jorge³ and Yuqing Zhang⁴, ¹Clinical Epidemiology, Boston University School of Medicine, Boston, MA, ²Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, ³Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, ⁴School Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA
Background/Purpose: Hydroxychloroquine (HCQ) is used for the long-term treatment of systemic lupus erythematosus (SLE) patients. HCQ is generally well-tolerated with wide-ranging benefits, including reduced disease…
Abstract Number: 2991 • 2017 ACR/ARHP Annual Meeting
Is a Growing Waistline over 8 Years Associated with Incident Functional Limitation and Low Health-Related Quality of Life in Knee Osteoarthritis?
Meredith Christiansen¹, Louise Thoma¹, Hiral Master¹, Dana Mathews² and Daniel White³, ¹Physical Therapy and Biomechanics and Movement Science, University of Delaware, Newark, DE, ²Physical Therapy, Biomechanics and Movement Science, University of Delaware, Newark, DE, ³Department of Physical Therapy, University of Delaware, Newark, DE
Background/Purpose: A large waist circumference (WC) is associated with walking difficulty in people with or at risk for knee osteoarthritis (OA). To date, it is…
Abstract Number: 2992 • 2017 ACR/ARHP Annual Meeting
Curbing the Opioid Epidemic: Predictors of Opioid Use in Juvenile Fibromyalgia Syndrome
Sabrina Gmuca¹, Rui Xiao², Andrea M. Knight³, David D. Sherry¹, Pamela F. Weiss⁴ and Jeffrey S. Gerber⁵, ¹Pediatric Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, ²Department of Biostatistics and Epidemiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, ³Division of Rheumatology, Center for Pediatric Clinical Effectiveness & PolicyLab, Children's Hospital of Philadelphia, Philadelphia, PA, ⁴Division of Rheumatology, Center for Pediatric Clincial Effectiveness, Children's Hospital of Philadelphia, Philadelphia, PA, ⁵Children's Hospital of Philadelphia, Philadelphia, PA
Background/Purpose: Despite the lack of evidence to support the use of opioids in the treatment of adult fibromyalgia syndrome, approximately 30% of patients receive an…
Abstract Number: 2993 • 2017 ACR/ARHP Annual Meeting
Knee Joint Sounds: A Non-Invasive Modality for Classifying Knee Joint Health in Juvenile Idiopathic Arthritis
Daniel Whittingslow¹, Beren Semiz², Lori Ponder³, Patricia Vega-Fernandez⁴, Omer Inan⁵ and Sampath Prahalad⁶, ¹Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, ²Electrical and Computer Engineering, Georgia Institute of Technology, Atlanta, GA, ³Emory University, Atlanta, GA, ⁴Pediatrics, Emory University School of Medicine, Atlanta, GA, ⁵Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, ⁶Pediatrics, Emory Children's Center, Atlanta, GA
Background/Purpose: Juvenile Idiopathic Arthritis (JIA) is the most common, chronic, childhood rheumatic disease and an important cause of disability. It is characterized by persistent inflammation…
Abstract Number: 2994 • 2017 ACR/ARHP Annual Meeting
Improving Outcomes Using a Treat to Target Approach and Clinical Decision Support in Polyarticular Juvenile Idiopathic Arthritis
Lisa Buckley¹, Eileen Ware², Genna Kreher², Lisa Wiater¹, Jay Mehta¹ and Jon (Sandy) Burnham¹, ¹Pediatric Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, ²Office of Clinical Quality Improvement, Children's Hospital of Philadelphia, Philadelphia, PA
Background/Purpose: Polyarticular juvenile idiopathic arthritis (Poly-JIA) causes pain, functional disability, and joint damage. Variation in Poly-JIA clinical assessment and treatment likely has a negative…
Abstract Number: 2995 • 2017 ACR/ARHP Annual Meeting
Pathogens in the Inflammatory Process of Periodontal Disease and Juvenile Idiopathic Arthritis
Nancy Delnay¹, Neil McNinch² and Mary Toth³, ¹Rheumatology, Akron Children's Hospital, Akron, OH, ²Rebecca Considine Research, Akron Children's Hospital, Akron, OH, ³Rheumatology, Children's Hospital Medical Center, Akron, OH
Background/Purpose: Juvenile idiopathic arthritis (JIA) and periodontal disease (PD) are both diseases of inflammation that can result in bone loss when the inflammatory process is…
Abstract Number: 2996 • 2017 ACR/ARHP Annual Meeting
Resilience and Transition Readiness in Pediatric SLE Patients
Jamie Lai¹, Lorene Nelson², Imelda Balboni¹, Tzielan Lee¹ and Joyce Hsu¹, ¹Pediatric Rheumatology, Stanford University, Palo Alto, CA, ²Health Research and Policy - Epidemiology, Stanford University, Palo Alto, CA
Background/Purpose: Childhood onset systemic lupus erythematosus (SLE) is a chronic autoimmune condition with high morbidity that requires long-lasting care through adulthood. Transition from pediatric to…

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