Abstracts Archive - Page 1584 of 2607 - ACR Meeting Abstracts

Abstract Number: 2951 • 2017 ACR/ARHP Annual Meeting
Responsiveness of the Patient Reported Outcomes Measurement Information System to Golimumab Intravenous and Infliximab Treatment in a Real World Clinical Trial in Rheumatoid Arthritis Patients
Jeffrey R. Curtis¹, Douglas Conaway², Joy Schechtman³, Aaron Broadwell⁴, Alan J. Kivitz⁵, Vance Bray⁶, Shelly Kafka⁷, Dennis Parenti⁷, Shawn Black⁷, Stephen Xu⁸, Wayne Langholff⁸ and Clifton O. Bingham III⁹, ¹Rheumatology & Immunology, University of Alabama at Birmingham, Birmingham, AL, ²Rheumatology/Medicine, Carolina Health Specialists, Myrtle Beach, SC, ³Sun Valley Arthritis Center LTD, Peoria, AZ, ⁴Rheumatology Osteoporosis Specialists, Shreveport, LA, ⁵Altoona Arthritis & Osteoporosis Center, Altoona, PA, ⁶Denver Arthritis Clinic, Denver, CO, ⁷Janssen Scientific Affairs, LLC, Horsham, PA, ⁸Janssen Research & Development, LLC, Spring House, PA, ⁹Rheumatology, Johns Hopkins University, Baltimore, MD
Background/Purpose: The Patient (Pt) Reported Outcomes Measurement Information System (PROMIS [P]) questionnaires developed by the NIH have been validated and are a feasible assessment tool…
Abstract Number: 2952 • 2017 ACR/ARHP Annual Meeting
A Randomized Controlled Trial (RCT) of an Internet-Based Self-Management Program for Adolescents with Juvenile Idiopathic Arthritis (JIA)
Jennifer N. Stinson¹, Sarah Campillo², Tania Cellucci³, Paul Dancey⁴, Ciarán M. Duffy⁵, Janet Ellsworth⁶, Brian M. Feldman⁷, Adam Huber⁸, Nicole Johnson⁹, Patrick McGrath⁸, Alan Rosenberg¹⁰, Natalie J. Shiff¹¹, Lynn R. Spiegel¹², Shirley M.L. Tse¹³, Lori Tucker¹⁴, J. Charles Victor¹⁵ and Stephanie Luca¹⁶, ¹Anesthesia and Pain Medicine, The Hospital for Sick Children, Toronto, ON, Canada, ²Montreal Children's Hospital, Montreal, QC, Canada, ³McMaster University, hamilton, ON, Canada, ⁴Pediatrics, Janeway Children's Hospital, St. John's, NL, Canada, ⁵Children's Hospital of Eastern Ontario and University of Ottawa, Ottawa, ON, Canada, ⁶University of Alberta, Edmonton, AB, Canada, ⁷Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ⁸IWK Health Centre, Halifax, NS, Canada, ⁹Alberta Children's Hospital, University of Calgary, Calgary, AB, Canada, ¹⁰Pediatrics, University of Saskatchewan, Saskatoon, SK, Canada, ¹¹University of Florida, Gainesville, FL, ¹²Rheumatology/Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada, ¹³Rheumatology, The Hospital for Sick Children, University of Toronto, Toronto, ON, Canada, ¹⁴BC Children's Hospital, Vancouver, BC, Canada, ¹⁵University of Toronto, Toronto, ON, Canada, ¹⁶The Hospital for Sick Children, Toronto, ON, Canada
Background/Purpose: Juvenile Idiopathic Arthritis (JIA) is a common chronic childhood illness associated with negative impact on health-related quality of life (HRQL). As teens mature, they…
Abstract Number: 2953 • 2017 ACR/ARHP Annual Meeting
Drivers of Satisfaction with Care in Lupus
Bhavika Sethi¹, Ailda Nika², Winston Sequeira³, Joel A. Block⁴, Sergio Toloza⁵, Ana Bertoli⁶, Ivana Blazevic⁷, Luis M. Vilá⁸, Ioana Moldovan⁹, Karina Torralba¹⁰, Davide Mazzoni¹¹, Elvira Cicognani¹¹, Sarfaraz Hasni¹², Berna Goker¹³, Seminur Haznedaroglu¹³, Josiane Bourré-Tessier¹⁴, Sandra V. Navarra¹⁵, Chi Chiu Mok¹⁶, Ann Clarke¹⁷, Michael Weisman¹⁸, Daniel J. Wallace¹⁹ and Meenakshi Jolly³, ¹University of Birmingham, Birmingham, United Kingdom, ²Rheumatology, Rush University Medical Center, Chicago, IL, ³Department of Medicine, Section of Rheumatology, Rush University Medical Center, Chicago, IL, ⁴Division of Rheumatology, Rush University Medical Center, Chicago, IL, ⁵Rheumatology, Hospital San Juan Batista, Catamarca, Argentina, Catamarca, Argentina, ⁶Instituto Reumatológico Strusberg, Córdoba, Argentina, ⁷Rheumatology, Universidad de Buenos Aires, Buenos Aires, Argentina, ⁸Department of Medicine, Division of Rheumatology, University of Puerto Rico Medical Sciences Campus, San Juan, Puerto Rico, ⁹Rheumatology, Beaver Medical Group, Redlands, CA, ¹⁰Division of Rheumatology, Department of Internal Medicine, Loma Linda University, Loma Linda, CA, ¹¹Department of Psychology, University of Bologna, Bologna, Italy, ¹²National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, ¹³Internal Medicine-Rheumatology, Gazi University Medical School, Ankara, Turkey, ¹⁴Rheumatology, University of Montreal, Montreal, QC, Canada, ¹⁵Rheumatology, University of Santo Tomas Hospital, Manila, Philippines, ¹⁶Medicine, Tuen Mun Hospital, Hong Kong, Hong Kong, ¹⁷Division of Rheumatology, University of Calgary, Calgary, AB, Canada, ¹⁸Cedars-Sinai Medical Center Division of Rheumatology, Los Angeles, CA, ¹⁹Rheumatology, Cedars-Sinai Medical Center, Beverly Hills, CA
Background/Purpose: Although survival in SLE has improved, quality of life (QOL) remains poor. Physicians aim to reduce suffering and improve health outcomes, while maximizing efficiency…
Abstract Number: 2954 • 2017 ACR/ARHP Annual Meeting
Achieving Balance and Diversity in Patient Engagement in Research: Perspectives from Patients
Graham Macdonald¹, Jenny Leese², Bao Chau Tran³, Alison Hoens³, Sheila Kerr⁴, Lianne Gulka⁵, Wendy Lum⁵ and Linda Li⁶, ¹Occupational Science and Occupational Therapy, University of British Columbia, Vancouver, BC, Canada, ²Physical Therapy, University of British Columbia, Vancouver, BC, Canada, ³Arthritis Research Canada, Richmond, BC, Canada, ⁴Arthritis Patient Advisory Board, Richmond, BC, Canada, ⁵Arthritis Research Canada Arthritis Patient Advisory Board, Richmond, BC, Canada, ⁶Rheumatology, Arthritis Research Canada, Richmond, BC, Canada
Background/Purpose: The movement for patient engagement in research aspires to greater inclusion of and collaboration with patients at virtually every point in the research cycle.…
Abstract Number: 2955 • 2017 ACR/ARHP Annual Meeting
Does Guideline-Based Care Improve Outcomes That Matter to Patients? Tighter Control, Less Suffering, and Greater Well-Being over the Past Decade in Canadian RA Patients
Susan J. Bartlett^1,2, Orit Schieir³, Marie-France Valois⁴, Carol A Hitchon⁵, Janet E. Pope⁶, Gilles Boire⁷, Boulos Haraoui⁸, Edward C. Keystone⁹, Diane Tin¹⁰, Carter Thorne¹¹ and Vivian P. Bykerk¹², ¹Department of Medicine, Division of ClinEpi, Rheumatology, Respirology, McGill University, Montreal, QC, Canada, ²Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ³Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada, ⁴McGill University, Montreal, QC, Canada, ⁵University of Manitoba, Winnipeg, MB, Canada, ⁶Department of Medicine, Division of Rheumatology, University of Western Ontario, St Joseph's Health Care, London, ON, Canada, ⁷Rheumatology Division, Centre Hospitalier Universitaire de Sherbrooke and Universite de Sherbrooke, Sherbrooke, QC, Canada, ⁸Institute de Rheumatologie, Montreal, QC, Canada, ⁹University of Toronto, Toronto, ON, Canada, ¹⁰The Arthritis Program, Southlake Regional Health Centre, Newmarket, ON, Canada, ¹¹University of Toronto, Newmarket, ON, Canada, ¹²2-005, Mt Sinai Hospital, Toronto, ON, Canada
Background/Purpose: Best practice recommendations can increase quality of care and improve clinical outcomes, however the impact of recommendations on outcomes that matter most to patients…
Abstract Number: 2956 • 2017 ACR/ARHP Annual Meeting
Evidence Based Recommendations for Corticosteroid Tapering/Discontinuation in New Onset Juvenile Dermatomyositis Patients from the Printo Trial
Gabriella Giancane¹, Claudio Lavarello¹, Angela Pistorio¹, Francesco Zulian¹, Bo Magnusson¹, Tadej Avcin¹, Fabrizia Corona¹, Valeria Gerloni², Serena Pastore¹, Roberto Marini¹, Silvana Martino¹, Anne Pagnier², Michel Rodiere¹, Christine Soler¹, Valda Stanevicha¹, Rebecca ten Cate³, Yosef Uziel¹, Jelena Vojinovic¹, Elena Fueri², Angelo Ravelli⁴, Alberto Martini⁵ and Nicolino Ruperto¹, ¹Istituto Giannina Gaslini - Pediatria II, Reumatologia - PRINTO, Genoa, Italy, ²Istituto Giannina Gaslini - Pediatria II, Reumatologia - PRINTO, Genova, Italy, ³Pediatric Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁴University of Genova, IRCCS Istituto Giannina Gaslini, Genova, Italy, ⁵Istituto Giannina Gaslini, Genoa, Italy
Background/Purpose: At present no clear evidence based guidelines exist to standardize the tapering and discontinuation of corticosteroids (CS) in juvenile dermatomyositis (JDM). To provide evidence-based…
Abstract Number: 2957 • 2017 ACR/ARHP Annual Meeting
Factors Associated with Cardiac Dysfunction in a Longitudinal Follow-up of Neonatal Lupus
Amit Saxena¹, Peter M. Izmirly², Rebecca Bomar², Shireen Golpanian², Deborah Friedman³ and Jill P. Buyon¹, ¹Rheumatology, New York University School of Medicine, New York, NY, ²New York University School of Medicine, New York, NY, ³New York Medical College, Valhalla, NY
Background/Purpose: There are minimal data and no longitudinal studies regarding the long term cardiac health of children with cardiac manifestations of neonatal lupus (NL). This…
Abstract Number: 2958 • 2017 ACR/ARHP Annual Meeting
Validation of Flare Criteria for Children and Adolescents with Systemic Lupus Erythematosus
Hermine I. Brunner¹, Michael J. Holland², Michael W. Beresford³, Nicolino Ruperto⁴, Stacy P. Ardoin⁵, Simone Appenzeller⁶, Clovis A Silva⁷, Glaucia V. Novak⁷, Daniela M. Lourenço⁸, Francisco Flores⁹, Beatrice Goilav¹⁰, Scott E. Wenderfer¹¹, Deborah M. Levy¹², Angelo Ravelli¹³, Raju Khubchandani¹⁴, Tadej Avcin¹⁵, Marisa S. Klein-Gitelman¹⁶, Brian M. Feldman¹⁷ and Jun Ying¹⁸, ¹Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ²Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ³On Behalf of the UK JSLE Study Group, Liverpool, United Kingdom, ⁴Istituto Giannina Gaslini, Genoa, Italy, ⁵Pediatric & Adult Rheumatology, The Ohio State University Wexner Medical Center, Columbus, OH, ⁶Pediatric Rheumatology Unit, State University of Campinas, Campinas, Brazil, ⁷Pediatric Rheumatology Unit, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ⁸Pediatric Rheumatology Unit, Faculdade de Medicina da Universidade de São Paulo, Sao Paulo, Brazil, ⁹Nephrology and Hypertension, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ¹⁰Albert Einstein College of Medicine/Montefiore Medical Center, New York, NY, ¹¹Pediatrics-Renal, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, ¹²Division of Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ¹³University of Genova, IRCCS Istituto Giannina Gaslini, Genova, Italy, ¹⁴Department of Paediatrics, Jaslok Hospital and Research Center, Mumbai, India, ¹⁵Istituto Giannina Gaslini - Pediatria II, Reumatologia - PRINTO, Genoa, Italy, ¹⁶Division of Pediatric Rheumatology/PDD PTD, Lurie Children's Hospital of Chicago/Northwestern University, Chicago, IL, ¹⁷Rheumatology, The Hospital for Sick Children, Toronto, ON, Canada, ¹⁸Center for Biostatistical Services, University of Cincinnati College of Medicine, Cincinnati, OH
Background/Purpose: Childhood-onset systemic lupus erythematosus (cSLE) is characterized by changing disease activity: episodes of improvement are often followed by episodes of worsening, i.e. flares. Considering…
Abstract Number: 2959 • 2017 ACR/ARHP Annual Meeting
Are Patients with Overlap Features Different from Patients without? Results from the Juvenile Systemic Scleroderma Cohort Www.Juvenile-Scleroderma.Com
Ivan Foeldvari¹, Jens Klotsche², Ozgur Kasapcopur³, Amra Adrovic⁴, Valda Stanevicha⁵, Maria Teresa Terreri⁶, Ekaterina Alexeeva⁷, Maria M. Katsicas⁸, Vanessa Smith⁹, Rolando Cimaz¹⁰, Mikhail Kostik¹¹, Thomas J. A. Lehman¹², Jordi Anton¹³, Walter A. Sifuentes-Giraldo¹⁴, Flavio Sztajnbok¹⁵, Tadey Avcin¹⁶, Mahesh Janarthanan¹⁷, Maria José Santos¹⁸, Dana Nemkova¹⁹, Cristina Battagliotti²⁰, Despina Eleftheriou²¹, Liora Harel²², Tilmann Kallinich²³, K Minden²⁴, Susan Mary Nielsen²⁵, Kathryn S. Torok²⁶, Yosef Uziel²⁷, Anne Stevens²⁸, Clarissa Pilkington²⁹ and Nicola Helmus¹, ¹Hamburg Center for Pediatric and Adolescent Rheumatology, Hamburg, Germany, ²Epidemiology unit, German Rheumatism Research Center, Berlin, Germany, ³Pediatric Rheumatology, Istanbul University, Cerrahpasa Medical School, Department of Pediatric Rheumatology, Istanbul, Turkey, ⁴Department of Pediatric Rheumatology, Istanbul University, Cerrahpasa Medical School, Istanbul, Turkey, ⁵Pediatric cathedra, Riga Stradiņš University, Riga, Latvia, ⁶Pediatric Rheumatology Unit, Federal University of São Paulo (UNIFESP - Universidade Federal de São Paulo), São Paulo, Brazil, ⁷Children's Health of RAMS and IM Sechenov First Moscow State Medical University, Moscow, Russian Federation, ⁸Service of Immunology & Rheumatology., Hospital de Pediatría Prof Dr JP Garrahan, Buenos Aires, Argentina, ⁹Faculty of Internal Medicine, Ghent University, Ghent, Belgium, ¹⁰Pediatrics, Ospedale Pediatrico Anna Meyer, Florence, Italy, ¹¹Hospital Pediatrics, State Pediatric Medical University, Saint-Petersburg, Russia, ¹²Pediatric Rheumatology, Hospital for Special Surgery Weill Cornell Medical College, New York, NY, ¹³pediatric Rheumatology, University Childrenxs Hospital, Barcelona, Spain, ¹⁴Rheumatology, Hospital Universitario Ramón y Cajal, Madrid, Spain, ¹⁵Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil, ¹⁶University Children's Hospital, Ljubljana, Slovenia, ¹⁷Pediatric Rheumatology, Chennai, India, ¹⁸Reuma.pt, Almada, Portugal, Almada, Portugal, ¹⁹Pediatric Rheumatology Unit, Department of Pediatrics and Adolescent Medicine, General University Hospital in Prague, Prague, Czech Republic, ²⁰Hospital de Niños Dr Orlando Alasia, Santa Fé, Argentina, ²¹Infection, Inflammation and Rheumatology, UCL Institute of Child Health, London, United Kingdom, ²²Schneider Children's Medical Center of Israel, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel, ²³Charité, Humbolt University Medicine Berlin, Berlin, Germany, ²⁴Charité – University of Medicine Berlin, Berlin, Germany, ²⁵Rigshospitalet, Copenhagen, Denmark, ²⁶Pediatric Rheumatology, University of Pittsburgh Med Ctr, Pittsburgh, PA, ²⁷Meir Medical Center, Kfar Saba, Israel, ²⁸University of Washington, Department of Pediatrics, Seattle, WA, ²⁹Paediatric Rheumatology, Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom
Background/Purpose: Juvenile systemic sclerosis (jSSc) patients with overlap features seems to have a better long term outcome1. There is currently no data, where the clinical…
Abstract Number: 2960 • 2017 ACR/ARHP Annual Meeting
Cardiovascular and Cerebrovascular Comorbidities of Juvenile Dermatomyositis in United States Children
Jonathan I. Silverberg¹, Lauren Kwa², Michael C. Kwa², Anne Laumann² and Kaveh Ardalan^3,4, ¹Dermatology, Preventive Medicine and Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, ²Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, ³Departments of Pediatrics and Medical Social Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL, ⁴Division of Rheumatology, Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago, IL
Background/Purpose: Juvenile dermatomyositis (JDM) is an autoimmune disease that causes vasculopathy and inflammation of skin and muscles. Previous studies in adult dermatomyositis suggest increased risks…
Abstract Number: 2961 • 2017 ACR/ARHP Annual Meeting
Body Composition and Myokine Levels in Juvenile Dermatomyositis and Associations with Physical Function
Birgit Nomeland Witczak¹, Kristin Godang², Jens Bollerslev^2,3, Thomas Schwartz^4,5, Berit Flatø^3,6, Ivar Sjaastad^3,4,7 and Helga Sanner^6,8, ¹Oslo University Hospital, Institute for Experimental Medical Research, Oslo University Hospital, Oslo, Norway, Oslo, Norway, ²Section of Specialized Endocrinology, Department of Endocrinology, Oslo University Hospital, Rikshospitalet, Oslo, Norway, Oslo, Norway, ³Institute for Clinical Medicine, University of Oslo, Oslo, Norway, Oslo, Norway, ⁴Institute for Experimental Medical Research, Oslo University Hospital, Oslo, Norway, Oslo, Norway, ⁵Department of Infectious Diseases, Oslo University Hospital, Oslo, Norway, Oslo, Norway, ⁶Department of Rheumatology, Oslo University Hospital, Rikshospitalet, Oslo, Norway, Oslo, Norway, ⁷Department of Cardiology, Oslo University Hospital, Oslo, Norway, Oslo, Norway, ⁸Norwegian National Advisory Unit on Rheumatic Diseases in Children and Adolescents, Oslo University Hospital, Rikshospitalet, Oslo, Norway, Oslo, Norway
Background/Purpose: JDM presents with proximal muscle weakness and atrophy is frequent. Still, body composition (BC) in JDM has not been widely studied, but is known…
Abstract Number: 2962 • 2017 ACR/ARHP Annual Meeting
MRI Results Following Discontinuation of Methotrexate in Patients with Rheumatoid Arthritis Treated with Subcutaneous Tocilizumab: Results from a Randomized Controlled Trial
Charles Peterfy¹, Joel Kremer², William F C Rigby³, Nora Singer⁴, Christine Birchwood⁵, Darcy Gill⁵, William Reiss⁵, Jinglan Pei⁵ and Margaret Michalska⁵, ¹Spire Sciences, Inc., Boca Raton, FL, ²Albany Medical College, Albany, NY, ³Geisel School of Medicine at Dartmouth, Lebanon, NH, ⁴Case Western Reserve University School of Medicine, Cleveland, OH, ⁵Genentech, Inc., South San Francisco, CA
Background/Purpose: Although previous studies have established the efficacy of tocilizumab (TCZ) initiated as monotherapy (MONO) for the treatment of rheumatoid arthritis (RA),1,2 changes in active…
Abstract Number: 2963 • 2017 ACR/ARHP Annual Meeting
Sirukumab Improves Synovial Vascularity As Measured By Power Doppler Sonography in Rheumatoid Arthritis Patients from As Early As Week 4 in a Phase 3 Trial
Bidisha Dasgupta¹, Kristen Sweet¹, Dick DeVries², Benjamin Hsu¹, Ian Gourley¹, Matthew Loza¹ and Peter C. Taylor³, ¹Janssen Research & Development, LLC, Spring House, PA, ²Janssen Biologics Europe, Leiden, Netherlands, ³Kennedy Institute of Rheumatology, University of Oxford, Oxford, United Kingdom
Background/Purpose: Ultrasound (US) is an established non-invasive tool for sensitively assessing disease activity at the individual‐joint level in rheumatoid arthritis (RA). Synovial thickness is detectable…
Abstract Number: 2964 • 2017 ACR/ARHP Annual Meeting
Structural Damage in Patients with Very Early RA Is Predicted with Clinical Measures of Baseline Disease Activity: DAS28 (CRP), SDAI, M-DAS28 and RAPID3 but Not CDAI
Edward C. Keystone¹, H Ahmad², Yusuf Yazici³, X Liu² and MJ Bergman⁴, ¹University of Toronto, Toronto, ON, Canada, ²Bristol-Myers Squibb, Princeton, NJ, ³New York University School of Medicine, New York, NY, ⁴Drexel University College of Medicine, Philadelphia, PA
Background/Purpose: Clinicians rely on time-efficient, validated disease activity assessments to help accurately predict disease progression in patients with RA. The utility of the Routine Assessment…
Abstract Number: 2965 • 2017 ACR/ARHP Annual Meeting
Non-Invasive Imaging Methods for Evaluating the Cardiovascular Involvement in Patients with Rheumatoid Arthritis before and after 18 Months of Treatment with Anti-TNF Drugs
Fabiola Atzeni¹, Luigi Gianturco², Laura Boccassini³, Piercarlo Sarzi-Puttini³ and Maurizio Turiel⁴, ¹Rheumatology Unit, ASST Fatebenefratelli - Sacco, L. Sacco University Hospital, Milano, Italy, ²Beato Matteo” Hospital, GSD Foundation, Vigevano, Italy, Vigevano, Italy, ³Rheumatology Unit, ASST Fatebenefratelli - Sacco, L. Sacco University Hospital, Milan, Italy, ⁴IRCCS, Galeazzi Orthopedic Institute, Dept. Biomedical Sciences for Health, University of Milan, Milan, Italy
Background/Purpose: The aim of this study was to evaluate left ventricular myocardial function with two- dimensional speckle tracking echocardiography (STE), in addition to conventional Doppler…

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