ACR Meeting Abstracts

ACR Meeting Abstracts

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  • Abstract Number: 2338 • 2016 ACR/ARHP Annual Meeting

    The Relationship Between Anxiety and Physical Activity Participation in Adults with Persistent Knee Pain and the Moderating Effect of Neighborhood Social Cohesion

    Maura D. Iversen1, Carolina Alvarez2, Rebecca J. Cleveland3, Joanne M. Jordan4,5 and Leigh F. Callahan6, 1Physical Therapy, Movement and Rehabilitation Sciences, Northeastern University, Boston, MA, 2Thurston Arthritis Research Center, Department of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, 3University of North Carolina at Chapel Hill, Chapel Hill, NC, 4University of North Carolina Dept of Epidemiology, Chapel Hill, NC, 5Rheumatology & Immunology Div, University of North Carolina Thurston Arthritis Center, Chapel Hill, NC, 6Thurston Arthritis Research Center, University of North Carolina, Chapel Hill, NC

    Background/Purpose : Behavioral theories suggest psychological distress reduces physical activity (PA) engagement via behavioral inhibition. Community factors such as neighborhood cohesion are also associated with…
  • Abstract Number: 2339 • 2016 ACR/ARHP Annual Meeting

    Does Physical Activity Change after Total Hip or Knee Arthroplasty: A Systematic Review and Meta-Analysis

    Thomas Hammett, Monica Austin, Aram Simonian, Robert Butler and Adam P. Goode, Orthopedic Surgery, Duke University, Durham, NC

    Background/Purpose:  Total joint replacement surgery has become one of the most common elective surgical procedures. Improvements in pain and physical function following total hip arthroplasty…
  • Abstract Number: 2340 • 2016 ACR/ARHP Annual Meeting

    Relation Between Range of Motion and Physical Activity While Recovering after Total Knee Replacement

    Hiral Master1, Louise Thoma1, Oliver Yost2, Meredith Christiansen1, Ryan Green3, Laura Schmitt1 and Daniel White4, 1Physical Therapy and Biomechanics and Movement Science, University of Delaware, Newark, DE, 2Physical Therapy and Biomechanical and Movement Science, University of Delaware, Newark, DE, 3Physical Therapy, University of Delaware, Newark, DE, 4Department of Physical Therapy, University of Delaware, Newark, DE

    Background/Purpose: Standard post-operative physical therapy (PT) for total knee replacement (TKR) aims to increase knee range of motion (ROM), which is important for walking and…
  • Abstract Number: 2341 • 2016 ACR/ARHP Annual Meeting

    Prediction of Triaxial Accelerometer Counts from Unaxial Acceleromenter Counts Among Adults with or at Risk for Knee Osteoarthritis: Data from the Osteoarthritis Initiative

    Julia (Jungwha) Lee1, Jing Song2, Rowland W. Chang3, Pamela Semanik4, Christine Pellegrini5, Linda S. Ehrlich-Jones6, Daniel Pinto7, Rebecca D. Jackson8 and Dorothy D. Dunlop2, 1Preventive Medicine/Biostatistics, Northwestern University Feinberg School of Medicine, Chicago, IL, 2Center for Healthcare Studies, Northwestern University Feinberg School of Medicine, Chicago, IL, 3Institute for Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 4College of Nursing, Rush University, Chicago, IL, 5Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 6Research CROR, Rehabilitation Institute Chicago, Chicago, IL, 7Department of Physical Therapy & Human Movement Sciences, Northwestern University, Chicago, IL, 8Ohio State University, Columbus, OH

    Background/Purpose: Physical activity monitoring studies in rheumatology initially used uniaxial accelerometers.  But advanced triaxial accelerometry technology replaced uniaxial accelerometers. Uniaxial devices measure accelerations in one…
  • Abstract Number: 2342 • 2016 ACR/ARHP Annual Meeting

    Understanding Patient Barriers and Facilitators to Healthy Eating and Physical Activity before and after Knee Replacement

    Christine Pellegrini1, Gwendolyn Ledford1, Rowland W. Chang2 and Kenzie Cameron3, 1Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 2Institute for Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 3General Internal Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL

    Background/Purpose:  Knee replacement typically results in reduced pain and improved physical function, yet post-operative physical activity levels often remain unchanged. Many patients also gain weight…
  • Abstract Number: 2343 • 2016 ACR/ARHP Annual Meeting

    A Phase 2, Multi-Center, Randomized, Double-Blind, Active-Controlled, Parallel Group Study to Evaluate the Safety and Dose Effectiveness of Intradermal Injections of Purified Apis Mellifera Toxin to Improve Pain and Physical Function in Patients with Osteoarthritis of the Knee

    Douglas R. Schumacher1, Anna Jakubowska2 and Christopher M.H. Kim3, 1Radiant Research, Columbus, OH, 2Apimeds, Inc., Jungwongu, Seongnam, Gyeonggido, Korea, The Republic of, 3CHA University, Bundanggu, Seongnam, Gyeongghido, Korea, The Republic of

    Background/Purpose: This Phase 2a/b trial evaluated the safety and dose effectiveness of honeybee toxin (purified Apis melliferatoxin) injections to improve pain and physical function in…
  • Abstract Number: 2344 • 2016 ACR/ARHP Annual Meeting

    Inflammation and Glucose Homeostasis Are Associated with Specific Structural Features Among Adults without Knee Osteoarthritis

    Alina Stout1, Mary Barbe2, Charles B. Eaton3, Mamta Amin4, Fatimah Al Eid1, Lori Lyn Price5, Bing Lu6, Grace H. Lo7, Ming Zhang8, Timothy E. McAlindon9 and Jeffrey Driban8, 1Rheumatology, Tufts Medical Center, Boston, MA, 2Temple University School of Medicine, Philadelphia, PA, 3Family Medicine and Community Health( Epidemiology), Alpert Medical School of Brown University, Pawtucket, RI, 4Department of Anatomy and Cell Biology, Temple University School of Medicine, Philadelphia, PA, 5Clinical Care Research, Tufts Medical Center, Boston, MA, 6Brigham & Women's Hospital and Harvard Medical School, Boston, MA, 7Immunology, Allergy, Rheumatology, Baylor College of Medicine, Houston, TX, 8Tufts Medical Center, Boston, MA, 9Division of Rheumatology, Tufts Medical Center, Boston, MA

    Background/Purpose: Adults with osteoarthritis (OA) have greater glucose concentrations and inflammation. It remains unclear if inflammation and glucose homeostasis are related to specific features of…
  • Abstract Number: 2345 • 2016 ACR/ARHP Annual Meeting

    Relation of Varus Knee Thrust during Walking to Two-Year Incidence of Frequent Ankle, Hip, and Lower Back Pain

    Alexandra Wink1, Carrie Brown2, Michael C. Nevitt3, Cora E. Lewis4, James Torner5, David T. Felson6, Leena Sharma7 and K. Douglas Gross8,9, 1Anatomy and Neurobiology, Boston University School of Medicine, Boston, MA, 2Boston University School of Public Health, Boston, MA, 3Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, 4University of Alabama Birmingham, Birmingham, AL, 5University of Iowa, UIowa, Iowa City, IA, 6Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, 7Division of Rheumatology, Northwestern University, Chicago, IL, 8Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, 9Physical Therapy, MGH Institute of Health Professions, Boston, MA

    Background/Purpose: Varus knee thrust is an abrupt change in frontal plane alignment of the tibiofemoral joint observed during gait. Thrust has been previously linked to…
  • Abstract Number: 2346 • 2016 ACR/ARHP Annual Meeting

    The Improving Motivation for Physical Activity in Arthritis Clinical Trial for Adults with Knee Osteoarthritis and Rheumatoid Arthritis

    Abigail Gilbert1, Julia (Jungwha) Lee2, Pamela Semanik3, Jing Song4, Christine Pellegrini5, Daniel Pinto6, Dorothy D. Dunlop4, Rowland W. Chang7 and Linda S. Ehrlich-Jones8, 1Northwestern University Feinberg School of Medicine, Chicago, IL, 2Preventive Medicine/Biostatistics, Northwestern University Feinberg School of Medicine, Chicago, IL, 3College of Nursing, Rush University, Chicago, IL, 4Center for Healthcare Studies, Northwestern University Feinberg School of Medicine, Chicago, IL, 5Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 6Department of Physical Therapy & Human Movement Sciences, Northwestern University, Chicago, IL, 7Institute for Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, 8Research CROR, Rehabilitation Institute Chicago, Chicago, IL

    Abstract: Background/Purpose: Insufficiently active adults experience reduced quality of life. Because half of adults with arthritis are physically inactive, we evaluated the additional effect of…
  • Abstract Number: 2347 • 2016 ACR/ARHP Annual Meeting

    Serum Levels of Resistin Are Associated with Synovial Inflammation and Knee Structural Changes in Patients with Symptomatic Knee Osteoarthritis

    WEIYU HAN1, Flavia M Cicuttini2, Graeme Jones3 and Changhai Ding3, 1Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia, 2Monash University, Department of Epidemiology and Preventive Medicine, Melbourne, Australia, 3Musculoskeletal Unit, Menzies Institute for Medical Research, University of Tasmania, Hobart, Australia

    Background/Purpose: Due to these sparse and inconsistent clinical data, our current study aims to describe the associations between serum levels of resistin, knee synovial inflammation…
  • Abstract Number: 2348 • 2016 ACR/ARHP Annual Meeting

    Does Arthritis in Other Joints and Spine Influence the 1-Year Outcome of Total Hip Replacement? a Prospective European Multicenter Cohort Study  Measuring the Influence of Musculoskeletal Morbidity

    Joerg Huber1, Paul Dieppe2, Karsten Dreinhoefer3, Klaus-Peter Günther4, Georg Ruflin5 and Andrew Judge6, 1Orthopedics, Triemli Spital, Zurich, Switzerland, 2Exeter Medical School, University of Exeter, Exeter, United Kingdom, 3Centre of Musculosceletal Surgery, Charité, Charite, Berlin, Berlin, Germany, 4University Center of Orthopedics and Traumatology, Technische Universität, Dresden, Germany, 5Orthopedics, Kantonsspital Aarau, Aarau, Switzerland, 6Musculoskeletal Biomedical Research Unit, University of Oxford, Oxford, United Kingdom

    Background/Purpose: Whilst arthritis in other affected joints and back pain is known to lead to worse outcomes following total hip replacement surgery, these risk factors…
  • Abstract Number: 2349 • 2016 ACR/ARHP Annual Meeting

    Longitudinal Construct Validity for Four Patient-Reported Outcomes Measurement Information System (PROMIS) Short Forms: Physical Function, Pain Interference, Depression, and Anxiety Among Adults with Knee Osteoarthritis

    Augustine C. Lee1, Lori Lyn Price2, Jeffrey B. Driban1, William F. Harvey1, Timothy E. McAlindon3, Angie Mae Rodday4, Hans E. Knopp5 and Chenchen Wang1, 1Rheumatology, Tufts Medical Center, Boston, MA, 2Biostatistics Research Center, Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, 3Division of Rheumatology, Tufts Medical Center, Boston, MA, 4Institute for Clinical Research and Health Policy Studies, Tufts Medical Center, Boston, MA, 5Physical Medicine and Rehabilitation, Tufts Medical Center, Boston, MA

      Background/Purpose: Patient-Reported Outcomes Measurement Information System (PROMIS) provides clinicians and researchers access to reliable, valid measures of health status to resolve many challenges associated…
  • Abstract Number: 2350 • 2016 ACR/ARHP Annual Meeting

    Radiographic Outcomes from a Randomized, Double-Blind, Placebo-Controlled, Phase 1 Study of a Novel, Intra-Articular, Injectable, Wnt Inhibitor (SM04690) in the Treatment of Osteoarthritis of the Knee

    Christopher J. Swearingen1, Sharmila Majumdar2, Ismail Simsek1, Anita DiFrancesco1, Jeymi Tambiah1 and Yusuf Yazici1, 1Samumed, LLC, San Diego, CA, 2University of California San Francisco, San Francisco, CA

    Background/Purpose: Knee osteoarthritis (OA) is characterized by pain, functional impairment, disability, and joint space narrowing due to degradation of articular cartilage and bone remodeling. The…
  • Abstract Number: 2351 • 2016 ACR/ARHP Annual Meeting

    Racial Differences in Magnetic Resonance Image-Based Three-Dimensional Bone Shape of the Knee: Data from the Osteoarthritis Initiative (OAI)

    Jing-Sheng Li1, Michael A Bowes2, David T. Felson3, Philip G. Conaghan4, Carrie Brown5 and Tuhina Neogi6, 1Boston University, Boston, MA, 2Imorphics Ltd, Manchester, United Kingdom, 3Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, 4Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds, Leeds, United Kingdom, 5Boston University School of Public Health, Boston, MA, 6Clinical Epidemiology, Boston University School of Medicine, Boston, MA

    Background/Purpose:  African Americans have higher prevalence and greater severity of knee osteoarthritis (OA) on radiographs compared with Caucasians. Magnetic resonance imaging (MRI)-based quantification of 3-dimensional…
  • Abstract Number: 2352 • 2016 ACR/ARHP Annual Meeting

    Obesity-Related Systemic Inflammation and Knee Synovitis

    Devyani Misra1, Tuhina Neogi2, Michael C. Nevitt3, James Torner4, Cora E. Lewis5 and David T. Felson6, 1Medicine, Section of, BUSM, Boston, MA, 2Clinical Epidemiology, BUSM, Boston, MA, 3Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, 4University of Iowa, UIowa, Iowa City, IA, 5University of Alabama Birmingham, Birmingham, AL, 6Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA

    Background/Purpose: Obesity, a major risk factor for knee osteoarthritis (OA), is a state of systemic inflammation through elaboration of adipokines (pro and anti-inflammatory cytokines) from…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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