Abstracts Archive - Page 1570 of 2425 - ACR Meeting Abstracts

Abstract Number: 2292 • 2016 ACR/ARHP Annual Meeting
Decreased Endothelial and Smooth Muscle Responsiveness in the Vasculature of Gout Patients Compared with Healthy Controls: Relationship Between Flow- and Nitrate-Mediated Dilation, Serum Urate and CRP
Aaron Garza Romero¹, Stuart Katz², Virginia Pike³, Daisy Bang¹, Binita Shah⁴, Talia Igel^1,5, Bruce Cronstein⁶, Irina Dektiarev², Jonathan Samuels⁷, Michael H. Pillinger⁸ and Svetlana Krasnokutsky Samuels⁹, ¹Medicine/Rheumatology, NYU School of Medicine, New York, NY, ²Medicine/Cardiology, NYU School of Medicine, New York, NY, ³Medicine/Rheumatology, NYU School of Medicine/NYU Hospital for Joint Diseases, New York, NY, ⁴NYU School of Medicine, Division of Cardiology, New York, NY, ⁵Monash University School of Medicine, Melbourne, Australia, ⁶Medicine, Division of Rheumatology, NYU School of Medicine, New York, NY, ⁷Department of Medicine, NYU School of Medicine, NYU Langone Medical Center, New York, NY, ⁸NYU School of Medicine, New York, NY, ⁹Svetlana Krasnokutsky, NYU Hospital for Joint Diseases, New York, NY
Background/Purpose: Gout is an independent risk factor for cardiovascular disease (CVD). Investigators studying the relationship between gout and CVD have focused on acute coronary outcomes,…
Abstract Number: 2293 • 2016 ACR/ARHP Annual Meeting
Cardiometabolic Risk and Subclinical Urate Deposits in Patients with Symptomatic Hyperuricemia and Metabolic Syndrome
Seoyoung C. Kim¹, Rajesh Garg², Stacy Smith³, Alyssa Wohlfahrt⁴, Anarosa Campos⁵, Kathleen Vanni⁴, Lauren K Lee⁶, Penny Wang⁶, Zhi Yu⁷, Marcelo Di Carli⁸ and Daniel H. Solomon⁹, ¹Rheumatology, Immunology and Allergy; Pharmacoepidemiologyand Pharmacoeconomics, Brigham and Women's Hospital, Boston, MA, ²Endocrinology, Brigham & Women's Hospital, Boston, MA, ³Radiology/Division of Musculoskeletal Imaging & Intervention, Brigham & Women's Hospital/ Harvard Medical School, Boston, MA, ⁴Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ⁵Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, ⁶Brigham and Women's Hospital, Boston, MA, ⁷Rheumatology Immunology & Allergy, Brigham and Women's Hospital, Boston, MA, ⁸Div. of Nuclear Medicine, Brigham and Women's Hospital, Boston, MA, ⁹Division of Rheumatology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA
Background/Purpose: Elevated serum uric acid (sUA) levels, with and without gout, are associated with systemic inflammation, coronary artery disease (CAD), chronic kidney disease, and diabetes.…
Abstract Number: 2294 • 2016 ACR/ARHP Annual Meeting
Uric Acid Production and Blood Pressure: The Role of Uric Acid Concentration As Well As Uric Acid Production
Lieke E.J.M. Scheepers^1,2, A. Boonen^1,2, P.C. Dagnelie^2,3,4, M.T. Schram^3,5, C.J.H, van der Kallen^3,5, R.M.A. Henry^3,5, A.A. Kroon^3,5, C.D.A. Stehouwer^3,6 and I.C.W. Arts^3,4,7, ¹Department of Internal Medicine, Division of Rheumatology, Maastricht University Medical Centre+, Maastricht, The Netherlands, Maastricht, Netherlands, ²CAPHRI School for Public Health and Primary Care, Maastricht University, Maastricht, The Netherlands, Maastricht, Netherlands, ³CARIM School for Cardiovascular Diseases, Maastricht University, Maastricht, The Netherlands, Maastricht, Netherlands, ⁴Department of Epidemiology, Maastricht University, Maastricht, The Netherlands, Maastricht, Netherlands, ⁵Department of Internal Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands, Maastricht, Netherlands, ⁶Internal Medicine, Department of Internal Medicine, Maastricht University Medical Centre, Maastricht, The Netherlands, Maastricht, Netherlands, ⁷MaCSBio Maastricht Centre for Systems Biology, Maastricht University, Maastricht, Netherlands
Background/Purpose: Blood pressure and hypertension are associated with uric acid, the end product of purine catabolism, but the underlying mechanism remainds unclear. During the final…
Abstract Number: 2295 • 2016 ACR/ARHP Annual Meeting
A Non-Linear Relationship Between Physical Activity and Serum Uric Acid Concentrations: Nhanes 2003-2004
Nicholas Holdgate¹, Carl Pieper^2,3, Tony Ning⁴, William E. Kraus^5,6 and Kim Huffman^1,5, ¹Rheumatology, Duke University Medical Center, Durham, NC, ²Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC, ³Biostatistics and Bioinformatics, Duke Pepper Center, Durham, NC, ⁴Triangle Orthopedic Associates, Durham, NC, ⁵Duke Pepper Center, Durham, NC, ⁶Medicine, Duke University Medical Center, Durham, NC
Background/Purpose: Hyperuricemia is a known cardio-metabolic risk factor as well as risk factor for gout. Physical activity has been found to improve many other cardio-metabolic…
Abstract Number: 2296 • 2016 ACR/ARHP Annual Meeting
The Influence of Androgen Deprivation Therapy on Serum Uric Acid Level
Jae Hyun Lee¹, Eun Hye Park², Sang Wan Chung³, Jaehyung Hur³, You Jung Ha³, Yeong Wook Song^1,4 and Yun Jong Lee^5,6, ¹Division of Rheumatology, Department of Internal Medicine, Seoul National University Hospital, Seoul, South Korea, ²Division of Rheumatology, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, The Republic of, ³Division of Rheumatology, Department of Internal Medicine, Division of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea, ⁴Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea, ⁵Internal Medicine, Seoul National University College of Medicine, Seoul, South Korea, ⁶Division of Rheumatology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea
Background/Purpose: The prevalence of hyperuricemia and gout suggests that sex hormones play a role in the gender difference with gout. Estrogen has been thought to…
Abstract Number: 2297 • 2016 ACR/ARHP Annual Meeting
Serum Urate and Its Association with Race in Young Adults: Baseline Analysis from a Randomized Clinical Trial
Michael B. Saddekni¹, Angelo L. Gaffo¹, Phillip J. Foster¹, Elizabeth J. Rahn¹, Stephanie R. Biggers¹, Peng Li² and Kenneth G. Saag¹, ¹Department of Medicine, Division of Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ²Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Increased levels of serum urate (sUA) have been reported in association with hypertension, chronic kidney disease, and obesity. All these conditions are over-represented in…
Abstract Number: 2298 • 2016 ACR/ARHP Annual Meeting
Incident Risk of Acute Gout Among Active Smokers: Data from Nationwide Inpatient Sample
Dilli Poudel¹, Paras Karmacharya¹ and Anthony Donato², ¹Internal Medicine, Reading Health System, WEST READING, PA, ²Internal medicine, Reading Health System, WEST READING, PA
Background/Purpose: Smoking has been found to be negatively correlated with serum uric acid levels by virtue of reduced production and increased consumption of endogenous anti-oxidant…
Abstract Number: 2299 • 2016 ACR/ARHP Annual Meeting
Predictors of Mortality in People with Recent Onset of Gout: A Prospective Observational Study
Zoe Vincent¹, Gregory Gamble², Meaghan House², Julie Knight¹, Anne Horne², William J. Taylor³ and Nicola Dalbeth¹, ¹University of Auckland, Auckland, New Zealand, ²Department of Medicine, University of Auckland, Auckland, New Zealand, ³University of Otago, Wellington, New Zealand
Background/Purpose: Many studies have reported that gout is associated with increased risk of cardiovascular events and mortality. However, information regarding gout disease severity is limited…
Abstract Number: 2300 • 2016 ACR/ARHP Annual Meeting
Tophaceous Gout and the Risk of Mortality: A General Population-Based Study
Hyon K. Choi¹, Leo Lu², Sharan K. Rai^3,4 and Yuqing Zhang⁵, ¹Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, ²Allergy, Immunology, and Rheumatology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, ³Arthritis Research Canada, Vancouver, BC, Canada, ⁴Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, ⁵Clinical Epidemiology and Training Unit, Boston University School of Medicine, Boston, MA
Tophaceous Gout and the Risk of Mortality: A General Population-Based Study Background/Purpose: A recent study based on data from a gout specialty clinic (N=706) found…
Abstract Number: 2301 • 2016 ACR/ARHP Annual Meeting
Gout and Subsequent Risk of Incident Erectile Dysfunction: A Population-Based Cohort Study from the United Kingdom
Alyshah Abdul Sultan¹, Christian Mallen², Richard Hayward¹, Sara Muller², Rebecca Whittle³, Matthew Hotston⁴ and Edward Roddy², ¹Research Institute of Primary Care & Health Sciences, Keele University, Keele, United Kingdom, ²Research Institute for Primary Care and Health Sciences, Keele University, Keele, United Kingdom, ³Research Institute for Primary Care and Health Sciences, Keele University, Stoke-on-Trent, United Kingdom, ⁴Urology, Royal Cornwall Hospital, Truro, United Kingdom
Background/Purpose: Gout is the most prevalent inflammatory arthritis, affecting 2.4% of adults in the UK. Recently, a link has been suggested between gout and erectile…
Abstract Number: 2303 • 2016 ACR/ARHP Annual Meeting
Trends in Gout and Rheumatoid Arthritis Hospitalizations in Canada from 2000-2011
Sharan K. Rai^1,2, J. Antonio Avina-Zubieta^2,3, Natalie McCormick^2,4, Mary A. De Vera^2,5, Diane Lacaille^2,6, Eric C. Sayre² and Hyon K. Choi^7,8, ¹Experimental Medicine, University of British Columbia, Vancouver, BC, Canada, ²Arthritis Research Canada, Richmond, BC, Canada, ³Division of Rheumatology, Department of Medicine, University of British Columbia, Vancouver, BC, Canada, ⁴Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada, ⁵Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, BC, Canada, ⁶Medicine, University of British Columbia, Vancouver, BC, Canada, ⁷Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, ⁸Arthritis Research Canada, Vancouver, BC, Canada
Background/Purpose: Gout and rheumatoid arthritis (RA) are the two most common forms of inflammatory arthritis worldwide. As hospitalizations for both conditions lead to substantial health…
Abstract Number: 2304 • 2016 ACR/ARHP Annual Meeting
Decreased Occurrence of Colon Cancer Among Gout Patients: Assessment By Physician Diagnosis and Colonoscopy
Anastasia Slobodnick^1,2, Svetlana Krasnokutsky Samuels³, Aaron Lehmann⁴, Robert Keenan⁵, Fritz Francois⁶ and Michael H. Pillinger^3,7, ¹Medicine/Rheumatology, NYU School of Medicine, New York, NY, ²Medicine/Rheumatology, VA New York Harbor Health Care System, NY Campus, New York, NY, ³VA New York Harbor Health Care System, New York, NY, ⁴Medicine/Rheumatology, NYU School of Medicine/NYU Hospital for Joint Diseases, New York, NY, ⁵Division of Rheumatology, Duke University, Durham, NC, ⁶Medicine/Gastroenterology, NYU School of Medicine, New York, NY, ⁷NYU School of Medicine, New York, NY
Background/Purpose: The relationship between gout and cancer remains unclear. Whereas some studies have reported possible anti-cancer benefits of uric acid and monosodium urate crystals, others…
Abstract Number: 2305 • 2016 ACR/ARHP Annual Meeting
Mapping the Topography of Gout Flares: Solutions for Flare Reporting in Gout Clinical Trials
Novell Teoh¹, Gregory Gamble², Anne Horne², William J. Taylor³, Kate Palmano⁴ and Nicola Dalbeth¹, ¹University of Auckland, Auckland, New Zealand, ²Department of Medicine, University of Auckland, Auckland, New Zealand, ³University of Otago, Wellington, New Zealand, ⁴Consultant Scientist, Waikato, New Zealand
Background/Purpose : Recurrent flares of inflammatory arthritis are the central clinical feature of gout. However, methods of gout flare reporting in research settings are inconsistent…
Abstract Number: 2306 • 2016 ACR/ARHP Annual Meeting
Improving Predictive Value of Gout Case Definitions in Electric Medical Records Utilizing Natural Language Processing: a Novel Informatics Approach
Sian Yik Lim¹, Sara R. Schoenfeld², Abhishek Chakrabortty³, Tianxi Cai³, Andrew Cagan⁴, Vivian Gainer⁵ and Hyon K. Choi⁶, ¹Rheumatology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, ²Rheumatology Unit, Massachusetts General Hospital, Harvard Medical School, Boston, MA, ³Department of Biostatistics, Harvard Medical School, Boston, MA, ⁴Research Computing, Partners HealthCare, Charlestown, MA, ⁵Partners HealthCare, Boston, MA, ⁶Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA
Background/Purpose: To date, most of the models used to identify gout cases within large administrative databases have relied solely only on administrative billing codes. The…
Abstract Number: 2307 • 2016 ACR/ARHP Annual Meeting
Influence of Season and Residential Environment on Development of Anti-Melanoma Differentiation-Associated Gene 5 Antibody-Positive Dermatomyositis with Interstitial Lung Disease
Naoshi Nishina¹, Shinji Sato², Yasushi Kawaguchi³, Atsushi Kawakami⁴, Maasa Tamura⁵, Kei Ikeda⁶, Takahiro Nunokawa⁷, Yoshinori Tanino⁸, Katsuaki Asakawa⁹, Yuko Kaneko¹⁰, Takahisa Gono¹¹, Kenichi Masui¹², Masataka Kuwana¹ and JAMI investigators, ¹Department of Allergy and Rheumatology, Nippon Medical School Graduate School of Medicine, Tokyo, Japan, ²Division of Rheumatology, Department of Internal Medicine, Tokai University School of Medicine, Isehara, Japan, ³Institute of Rheumatology, Tokyo Women's Medical University, Tokyo, Japan, ⁴Unit of Translational Medicine, Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ⁵Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, Yokohama, Japan, ⁶Department of Allergy and Clinical Immunology, Chiba University Hospital, Chiba, Japan, ⁷Department of Rheumatic Diseases, Tokyo Metropolitan Tama Medical Center, Tokyo, Japan, ⁸Department of Pulmonary Medicine, Fukushima Medical University School of Medicine, Fukushima, Japan, ⁹Division of Respiratory Medicine, Niigata University Medical and Dental Hospital, Niigata, Japan, ¹⁰Division of Rheumatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan, ¹¹Department of Rheumatology, Jichi Medical University Saitama Medical Center, Saitama, Japan, ¹²Department of Anesthesiology, National Defense Medical College School of Medicine, Tokorozawa, Japan
Background/Purpose: Environmental triggers such as infection are considered to be involved in pathogenesis of polymyositis (PM) and dermatomyositis (DM). This study was aimed to investigate…

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