Abstracts Archive - Page 1545 of 2607 - ACR Meeting Abstracts

Abstract Number: 2366 • 2017 ACR/ARHP Annual Meeting
High Uric Acid As a Risk Factor for Cardiovascular Diseases in Rheumatoid Arthritis Patients
Adeeba Al-Herz¹, Ali Aldei¹, Khulood Saleh², Adel Al-Awadhi³, Waleed Al-Kandari², Eman Hasan⁴, Aqeel Ghanem⁵, Mohammad Hussain⁴, Ibrahim Nahar⁵, Fatemah Abutiban⁶, Ahmad Alenizi⁶, Yaser Ali⁵, Hebah Alhajeri⁵, Sawsan Hayat⁵, Ahmad Khadrawy², Ammad Fazal², Khaled Mokaddem¹, Agaz Zaman⁵, Ghada Mazloum⁵, Youssef Bartella¹, Sally Hamed¹, Ramia Alsouk⁶ and Ahmed Al-Saber⁷, ¹Rheumatology, Al-Amiri Hospital, Kuwait city, Kuwait, ²Rheumatology, Farwania Hospital, Farwania, Kuwait, ³Faculty of Medicine, Kuwait, Kuwait, ⁴Al-Amiri Hospital, Kuwait city, Kuwait, ⁵Rheumatology, Mubarak Al-Kabeer Hospital, Hawally, Kuwait, ⁶Rheumatology, Jahra Hospital, Jahra, Kuwait, ⁷Department of Mathematics, Kuwait Technical College, Kuwait city, Kuwait
Background/Purpose: Rheumatoid arthritis (RA) patients have an increased risk of cardiovascular diseases (CVD). It is unclear whether an elevated serum uric acid (UA) further increases…
Abstract Number: 2367 • 2017 ACR/ARHP Annual Meeting
The Effect of Glucocorticoids on Bone Mineral Density in Patients with Rheumatoid Arthritis: a Systematic Review and Meta-Analysis
Anne-Birgitte Blavnsfeldt^1,2, Malissa Dawn Thomsen³, Simon Tarp⁴, Bente Langdahl^2,5, Ellen-Margrethe Hauge^2,6 and Annette de Thurah^7,8, ¹Rheumatology, Aarhus Universityhospital, Aarhus C, Denmark, ²Department of Clinical Medicine, Aarhus University, Aarhus C, Denmark, ³Diagnostic Centre, Silkeborg Regional Hospital, Silkeborg, Denmark, ⁴The Parker Institute, Bispebjerg & Frederiksberg Hospital, Copenhagen, Denmark, ⁵Endocrinology, Aarhus University Hospital, Aarhus, Denmark, ⁶Aarhus Universityhospital, Aarhus C, Denmark, ⁷Department of Rheumatology, Aarhus University Hospital, Aarhus, DK, Aarhus, Denmark, ⁸Department of Clinical Medicine, Aarhus University, Aarhus, Denmark
Background/Purpose: The role of glucocorticoids (GCs) in the treatment of rheumatoid arthritis (RA) is widely debated. GCs stimulate bone resorption and impair bone formation. Inflammatory…
Abstract Number: 2368 • 2017 ACR/ARHP Annual Meeting
Global Circumferential Strain By Assessed a Feature Tracking Cardiac Magnetic Resonance (CMR) Imaging Was Associated with Myocardial Fibrosis in RA Patients
Yasuyuki Kobayashi¹, Hitomi Kobayashi², Isamu Yokoe³, Atsuma Nishiwaki⁴, Akiyuki Kotoku⁵ and Masami Takei⁴, ¹Advanced Biomedical Imaging Informatics, St.Marianna University School of Medicine, Kawasaki, Japan, ²Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, ³Rheumatology, Kyoundo Hospital, Sasaki Institute, Tokyo, Japan, ⁴Division of Hematology and Rheumatology, Nihon University School of Medicine, Tokyo, Japan, ⁵Advanced Biomedical Imaging Informatics, St. Marianna University School of Medicine, Kawasaki, Japan
Background/Purpose: Individuals with RA have a 1.5-2.0 fold higher risk of developing congestive heart failure (CHF) than the general population. It is important to understand…
Abstract Number: 2369 • 2017 ACR/ARHP Annual Meeting
Relationship of Bone Mineral Density and Inflammatory Burden with Carotid Plaque Formation in Rheumatoid Arthritis: A 5-Year Prospective Study
Na Ri Kim, Jong Wan Kang, Jung Su Eun, Ji Hun Kim, Jin Young Kang, Gi Bum Bae, Sang Jin Lee, Eon Jeong Nam and Young Mo Kang, Division of Rheumatology, Department of Internal Medicine, Kyungpook National University School of Medicine, Daegu, Korea, Republic of (South)
Background/Purpose: Rheumatoid arthritis (RA) is a chronic and systemic inflammatory disease. The incidence of the cardiovascular (CV) disease is significantly increased in patients with RA…
Abstract Number: 2370 • 2017 ACR/ARHP Annual Meeting
Endothelial Nitric Oxide Synthase Gene Polymorphism As a Risk Factor of Hypertension in Patients with Rheumatoid Arthritis
Mykola Stanislavchuk^1,2, Kateryna Zaichko² and Ayad Sulaiman², ¹Internal Medicine, VNMU n.a. M. Pirogov, Vinnytsia, Ukraine, ²Rheumatology, Vinnytsia Regional Clinical Hospital, Vinnytsia, Ukraine
Background/Purpose: Rheumatoid arthritis (RA) and hypertension (HT) are multifactorial polygenic diseases. The incidence of hypertension in patients with RA is higher than in the general…
Abstract Number: 2371 • 2017 ACR/ARHP Annual Meeting
The Efficacy of Tofacitinib in Patients with Rheumatoid Arthritis Stratified By Baseline Body Mass Index
Ara Dikranian¹, Miguel Angel Gonzalez-Gay², Frank Wellborne³, Jose Maria Alvaro-Gracia⁴, Liza Takiya⁵, Lori Stockert⁵, Douglass Chapman⁶, Svitlana Tatulych⁷, Palle Dahl⁸ and Jeffrey R. Curtis⁹, ¹Cabrillo Center for Rheumatic Disease, San Diego, CA, ²Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain, ³Houston Institute for Clinical Research, Houston, TX, ⁴Hospital Universitario de La Princesa, IIS Princesa, Madrid, Spain, ⁵Pfizer Inc, Collegeville, PA, ⁶Pfizer Inc, New York, NY, ⁷Pfizer Inc, Groton, CT, ⁸Pfizer Inc, Ballerup, Denmark, ⁹University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid arthritis (RA). This post-hoc analysis aims to explore the efficacy of tofacitinib…
Abstract Number: 2372 • 2017 ACR/ARHP Annual Meeting
Obesity and the Impact on Treat to Target Goals and Functional Ability in RA. Results from Two Multi-Centre UK Inception Cohorts
Elena Nikiphorou¹, Sam Norton², Patrick Kiely³ and Adam Young⁴, ¹Academic Rheumatology Department, King's College London, London, United Kingdom, ²Academic Rheumatology, King´s College London, London, United Kingdom, ³St George's Hospital, London, United Kingdom, ⁴University of Hertfordshire, Hertford, United Kingdom
Background/Purpose: The links between inflammation, obesity and joint dysfunction are well established. How these translate into clinical disease activity and functional disability in rheumatoid arthritis…
Abstract Number: 2373 • 2017 ACR/ARHP Annual Meeting
Low or High BMI Negatively Impacts RA Disease Activity in an Asian RA Cohort
Claire Teo¹, KP Leong², CM Woo³, X Tang³, J WL Tan⁴, TY Lian⁴ and ET Koh², ¹Rheumatology, Allergy and Immunology Department, Tan Tock Seng Hospital, Singapore, Singapore, ²Rheumatology/Allerg/Immunology, Tan Tock Seng Hospital, Singapore, Singapore, ³Clinical Research and Innovation Office, Tan Tock Seng Hospital, Singapore, Singapore, ⁴Department of Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, Singapore, Singapore
Background/Purpose: The association of body mass index (BMI) with the outcomes of rheumatoid arthritis (RA) has been inconsistent in the literature. It is postulated that…
Abstract Number: 2374 • 2017 ACR/ARHP Annual Meeting
Obesity Impacts ESR and Not Other Measures of Rheumatoid Arthritis Disease Activity
Ana Maheshwari¹, Oumoul Barry¹ and MJ Bergman², ¹Internal Medicine, Mercy Catholic Medical Center, Darby, PA, ²Medicine, Drexel University College of Medicine, Philadelphia, PA
Background/Purpose: Disease activity measurement is a cornerstone to treat to target strategy. The impact of body mass index (BMI) on disease activity in rheumatoid arthritis…
Abstract Number: 2375 • 2017 ACR/ARHP Annual Meeting
Does the Body Mass Index Have Any Influence in the Characteristics of Early Arthritis Patients?
Pablo Moreno Fresneda¹, Lola Martínez-Quintanilla Jiménez¹, Ana M. Ortiz Garcia², Eva Tomero³, Rosario García-Vicuña⁴ and Isidoro Gonzalez-Alvaro², ¹Rheumatology, Rheumatology Division, Hospital Universitario La Princesa, IIS-IP, Madrid, Spain, ²Rheumatology, Rheumatology Service, Hospital Universitario de La Princesa, IIS-IP, Madrid, Spain, ³Hospital La Princesa. Madrid., Madrid, Spain, ⁴Rheumatology, Hospital Universitario de La Princesa. IIS La Princesa, Madrid, Spain
Background/Purpose: Obesity has been proposed as a risk factor to develop rheumatoid arthritis (RA) and it has been associated with a worse response to several…
Abstract Number: 2376 • 2017 ACR/ARHP Annual Meeting
Weight Histories Expose the Systematic Underestimation of the Risks of Obesity on Mortality in Rheumatoid Arthritis
Joshua Baker¹, Bryant R. England², Ted R. Mikuls³ and Kaleb Michaud⁴, ¹Medicine/Rheumatology, University of Pennsylvania, Philadelphia, PA, ²Division of Rheumatology & Immunology, Department of Internal Medicine, Nebraska-Western IA VA Health Care System & University of Nebraska Medical Center, Omaha, NE, ³Internal Medicine, Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE, ⁴University of Nebraska Medical Center, Omaha, NE
Background/Purpose: Emerging evidence suggests that long-term weight loss is an important confounder that results in an underestimation of the risks of obesity in chronic illness.…
Abstract Number: 2377 • 2017 ACR/ARHP Annual Meeting
Impact of Body Mass Index and Weight Loss on Incident Disability in Patients with Rheumatoid Arthritis
Joshua Baker¹, Ted R. Mikuls², Bryant R. England³, Michael D. George⁴, Grant Cannon⁵, Harlan Sayles⁶, Brian Sauer⁵, Liron Caplan⁷ and Kaleb Michaud⁶, ¹Medicine/Rheumatology, University of Pennsylvania, Philadelphia, PA, ²Internal Medicine, Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE, ³Division of Rheumatology & Immunology, Department of Internal Medicine, Nebraska-Western IA VA Health Care System & University of Nebraska Medical Center, Omaha, NE, ⁴Division of Rheumatology, University of Pennsylvania, Philadelphia, PA, ⁵Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, ⁶University of Nebraska Medical Center, Omaha, NE, ⁷Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO
Background/Purpose: Obese patients with rheumatoid arthritis (RA) have greater disability in cross-sectional studies. There are no long-term studies that assess trajectories of disability among individuals…
Abstract Number: 2378 • 2017 ACR/ARHP Annual Meeting
Body Mass Index and Persistence of Conventional Dmards and TNF Inhibitors in Rheumatoid Arthritis
Caroline McCulley¹, Ted R. Mikuls², Jennifer Barton³, Grant Cannon⁴, Brian C. Sauer, PhD⁵, Liron Caplan⁶, Bryant R. England⁷, Chia-Chen Teng⁸ and Joshua Baker⁹, ¹Rheumatology, Oregon Health & Science University, Portland, OR, ²Internal Medicine, Division of Rheumatology, University of Nebraska Medical Center, Omaha, NE, ³VA Portland Health Care System, Portland, OR, ⁴Salt Lake City VA Medical Center and University of Utah, Salt Lake City, UT, ⁵Salt Lake City VA and University of Utah, Salt Lake City, UT, ⁶Division of Rheumatology, University of Colorado School of Medicine, Aurora, CO, ⁷Division of Rheumatology & Immunology, Department of Internal Medicine, Nebraska-Western IA VA Health Care System & University of Nebraska Medical Center, Omaha, NE, ⁸Rheumatology, University of Utah, Salt Lake City, UT, ⁹Rheumatology, University of Pennsylvania, Philadelphia, PA
Background/Purpose: Low body mass index (BMI) is associated with more destructive disease in rheumatoid arthritis (RA). Paradoxically, obese patients have been shown in studies to…
Abstract Number: 2379 • 2017 ACR/ARHP Annual Meeting
Effect of DKK-1 and Osteoprotegerin on Bone Mass in Tightly Controlled Rheumatoid Arthritis
Javier Narváez¹, Irene Martin-Esteve², Andrea Zacarias³, Pedro Alia⁴, Estibaliz Loza⁵, Loreto Carmona⁵, Joan Miquel Nolla² and Carmen Gomez Vaquero⁶, ¹Rheumatology Department, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Spain, ²Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain, ³Hospital Universitari de Bellvitge, Barcelona, Spain, ⁴Clinical Laboratory Service, Hospital Universitari de Bellvitge - IDIBELL, Barcelona, Spain, ⁵Instituto de Salud Musculoesquelética (InMusc), Madrid, Spain, ⁶Department of Rheumatology, Hospital Universitario de Bellvitge, Barcelona, Spain
Background/Purpose: To analyze the association between osteoprotegerin (OPG) and Dickkopf-related protein 1 (DKK-1) and the annual percent change (Δ%) in bone mineral density (BMD) in patients…
Abstract Number: 2380 • 2017 ACR/ARHP Annual Meeting
The Use of Fibroscan in Detecting Early Liver Fibrosis in RA Patients on Long Term MTX with Normal Liver Enzymes
Malack Alachkar¹, T Mathialahan², Sandra Walsh² and Vun Lim³, ¹Rheumatology, The Pennine Acute Hospitals NHS Trust, Manchester, United Kingdom, ²Gastroenterology, Wrexham Maelor Hospital, Betsi Cadwaladr University Health Board, Wrexham, United Kingdom, ³Rheumatology, Wrexham Maelor Hospital, Betsi Cadwaladr University Health Board, Wrexham, United Kingdom
Background/Purpose: FibroScan (FS) is a non-invasive investigation that allows assessment of possible liver fibrosis by measuring liver stiffness. There are studies which confirm that MTX-related…

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