Abstracts Archive - Page 1543 of 2425 - ACR Meeting Abstracts

Abstract Number: 1885 • 2016 ACR/ARHP Annual Meeting
Can Nailfold Videocapillaroscopy Images be Interpreted Reliably By Different Observers? Results of an Inter-Reader and Intra-Reader Exercise Among Rheumatologists with Different Experience in This Field
Tatiana Sofia Rodriguez-Reyna¹, Chiara Bertolazzi², Angelica Vargas Guerrero³, Marwin Gutierrez⁴, Gabriela Hernandez-Molina⁵, Marcelo Audisio⁶, Susana Roverano⁷, Margarita González de Urizar⁸, José Francisco Díaz Coto⁹, Blanca Herrera Velasco¹⁰, Mijahil Cornejo Ortega¹¹, Ana María Sapag Durán¹², Janeth Villegas Guzmán¹³, Luìs Fernando Medina Quintero¹⁴, Mirtha Sabelli¹⁵, Carlos Velasquez¹⁶, Sandy Sapag Durán¹⁷, Oscar Sedano¹⁸, Martín Zapata Zúñiga¹⁹, Maria Fonseca²⁰, Maurizio Cutolo²¹ and PANLAR Capillaroscopy Group, ¹Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, ²Rheumatology, Instituto Nacional de Rehabilitación, Mexico City, Mexico, ³Rheumatology, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico, ⁴Instituto Nacional de Rehabilitación, Mexico, Mexico, ⁵Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico City, Mexico, ⁶Servicio de Reumatología del Hospital Nacional de Clínicas, Córdoba, Argentina, ⁷Rheumatology, Hospital Jose Maria Cullen, Santa Fe, Argentina, ⁸Rheumatology, Hospital San Ramón, Ciudad del Este, Paraguay, ⁹Rheumatology, Hospital Clínica Bíblica, San José, Costa Rica, ¹⁰Rheumatology, Universidad de San Fancisco Xavier de Chuquisaca, Sucre, Bolivia (Plurinational State of), ¹¹Rheumatology, Hospital Nacional Arzobispo Loayza, Lima, Peru, ¹²Rheumatology, Hospital Universitario Japonés, Santa Cruz, Bolivia (Plurinational State of), ¹³Rheumatology, Hospital Nacional Dos de Mayo, Lima, Peru, ¹⁴Internal Medicine, Universidad del Valle, Cali, Colombia, ¹⁵Rheumatology Unit, Internal Medicine Service, Hospital Italiano de Buenos Aires, Instituto Universitario Hospital Italiano de Buenos Aires, and Fundacion PM Catoggio, Buenos Aires, Argentina, ¹⁶Clínica Universitaria Bolivariana, Universidad Pontificia Bolivariana, Medellín, Colombia, ¹⁷Reumatología, Instituto de Investigación en Reumatología Sapag & Sapag, Santa Cruz de la Sierra, Bolivia (Plurinational State of), ¹⁸Rheumatology, Hospital Marino Molina Scippa ESSALUD, Lima, Peru, ¹⁹Rheumatology, Hospitl General Jerez, Jerez, Mexico, ²⁰Rheumatology, Hospital Bernardino Rivadavia, Buenos Aires, Argentina, ²¹Research Laboratory and Academic Division of Clinical Rheumatology, Department of Internal Medicine, University of Genova, Genoa, Italy, Genova, Italy
Background/Purpose: Nailfold videocapillaroscopy (VCP) has become an established method to assess the microcirculation in patients with Raynaud’s phenomenon and connective tissue diseases. The 2013 Systemic…
Abstract Number: 1886 • 2016 ACR/ARHP Annual Meeting
Right Ventricular Load-Adaptability and Response to Therapy in Scleroderma Versus Idiopathic Pulmonary Arterial Hypertension
Sarah French¹, Nadia Ouazani², Myriam Amsallem², Shufeng Li³, Roham T. Zamanian⁴, Lorinda Chung⁵ and Francois Haddad², ¹Internal Medicine, Stanford University Medical Center, Palo Alto, CA, ²Cardiology, Stanford University Medical Center, Palo Alto, CA, ³Biostatistics, Stanford University Medical Center, Palo Alto, CA, ⁴Stanford University Medical Center, Palo Alto, CA, ⁵Rheumatology, Stanford University Medical Center, Palo Alto, CA
Background/Purpose: Recent studies have suggested that right ventricular (RV) adaptation in patients with scleroderma-associated pulmonary arterial hypertension (SSc-PAH) is worse than in patients with idiopathic…
Abstract Number: 1887 • 2016 ACR/ARHP Annual Meeting
Olfactory Impairment Is Associate with Cognitive Dysfunction and Regional Brain Atrophy in Systemic Sclerosis
Mariana Freschi Bombini¹, Fernando A. Peres², Nailu A. Sinicato³, Aline Tamires Lapa², Leticia Rittner⁴, Roberto Souza⁵, Ana Paula del Rio¹, João Francisco Marques-Neto¹ and Simone Appenzeller¹, ¹State University of Campinas, Campinas, Brazil, ²Medicine, State University of Campinas, Campinas, Brazil, ³Pediatrics, State University of Campinas, Campinas, Brazil, ⁴Electrical Engineering, State University of Campinas, Campinas, Brazil, ⁵State University of Campinas, campinas, Brazil
Background/Purpose: Several factors has been described as responsible for the association between olfactory impairment and brain regions. In systemic sclerosis (SSc) the olfactory interaction has…
Abstract Number: 1888 • 2016 ACR/ARHP Annual Meeting
Reliability, Validity, and Sensitivity to Change of the Simplified Duruoz Hand Index in Systemic Sclerosis
Ana Maria Gheorghiu¹, Hermina Gyorfi¹, Razvan Capota¹, Alexandru Matei¹, Raida Oneata¹, Liviu Macovei¹, Mihaela Milicescu¹, Mariana Sasu¹, Mihai Bojinca², Victor Stoica¹ and Carina Mihai¹, ¹Carol Davila University of Medicine and Pharmacy, Internal Medicine and Rheumatology Department, Cantacuzino Clinical Hospital, Bucharest, Romania, ²Carol Davila University of Medicine and Pharmacy, Internal Medicine and Rheumatology Department, Cantacuzino Clinical Hospital, Bucuresti, Romania
Background/Purpose: Hand involvement is observed in almost all patients with Systemic Sclerosis (SSc), and is due in various proportions to skin and tendon fibrosis, arthritis…
Abstract Number: 1889 • 2016 ACR/ARHP Annual Meeting
Predictors of Acro-Osteolysis in Systemic Sclerosis
Ashraf Raslan¹ and Vivien Hsu², ¹Medicine, Rutgers-RWJ Medical School, Jersey City, NJ, ²Rheumatology, RWJ Med Schl Scleroderma Prog, New Brunswick, NJ
Background/Purpose: Acro-osteolysis (AO) is the bony resorption on the distal tufts of the digits, a characteristic radiological finding in Systemic Sclerosis (SSc) with estimated prevalence…
Abstract Number: 1890 • 2016 ACR/ARHP Annual Meeting
Functional Disability and Its Predictors in Systemic Sclerosis: A Study from the Desscipher Project within the European Scleroderma Trials and Research Group
Veronika K. Jaeger¹, Lazlo Czirjak², Veronika Lóránd², Gabriele Valentini³, Serena Vettori⁴, Francesco Del Galdo⁵, Giuseppina Abignano⁶, Oliver Distler⁷, Britta Maurer⁷, Christopher Denton⁸, Svetlana Nihtyanova⁹, Yannick Allanore¹⁰, Jerome Avouac¹¹, Gabriela Riemekasten¹², Elise Siegert¹³, Dörte Huscher¹⁴, Marco Matucci-Cerinic¹⁵, Serena Guiducci¹⁶, Marc Frerix¹⁷, Ingo H. Tarner¹⁸, Beata Garay-Toth¹⁹, Lidiya P. Ananieva²⁰, Franco Cozzi²¹, Sule Yavuz²², Nicolas Hunzelmann²³, Alessandra Vacca²⁴, Tim Schmeiser²⁵, Simona Rednic²⁶, Valeria Riccieri²⁷, Brigitte Krummel-Lorenz²⁸, Armando Gabrielli²⁹, Paloma Garcia De La Peña³⁰, Codrina Ancuta³¹, Ulf Müller-Ladner³², Ulrich A. Walker¹ and on behalf of the DeSScipher Consortium and contributing EUSTAR centres, ¹Department of Rheumatology, University Hospital Basel, Basel, Switzerland, ²Department of Rheumatology and Immunology, University of Pécs, Pécs, Hungary, ³Internal and Experimental Medicine, Rheumatology Unit, Second University of Naples, Naples, Italy, ⁴Department of Internal and Experimental Medicine, Rheumatology Unit, Second University of Naples, Naples, Italy, ⁵Leeds Institute of Rheumatic and Musculoskeletal Medicine, University of Leeds and NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom, ⁶Clinical and Experimental Medicine, Second University of Naples, Napoli, Italy, ⁷Department of Rheumatology, University Hospital Zurich, Zurich, Switzerland, ⁸Division of Medicine, Centre for Rheumatology and Connective Tissue Disease, University College London, London, United Kingdom, ⁹Centre for Rheumatology and Connective Tissue Diseases, University College London Medical School, Royal Free Hospital, London, United Kingdom, ¹⁰Rheumatology, Paris Descartes University, Paris, France, ¹¹Department of Rheumatology, University of Paris Descartes, Paris, France, ¹²Department of Rheumatology, Universitatsklinikum Schleswig-Holstein, Lubeck, Germany, ¹³Rheumatology and Clinical Immunology, Charité – University Medicine Berlin, Berlin, Germany, ¹⁴Epidemiology, German Rheumatism Research Centre, Berlin, Germany, ¹⁵Department of Medicine, Division of Rheumatology, University of Florence, Florence, Italy, ¹⁶Department of Experimental and Clinical Medicine, Division of Rheumatology, University of Florence, Florence, Italy, ¹⁷Department of Rheumatology and Clinical Immunology, Justus-Liebig-University Giessen, Kerckhoff-Klinik, Bad Nauheim, Germany, ¹⁸Rheumatology and Clinical Immunology, Justus-Liebig-University of Giessen, Kerckhoff-Klinik, Bad Nauheim, Germany, ¹⁹FESCA, Budapest, Hungary, ²⁰Microcirculation and Inflammation, Research Institute of Rheumatology RAMS, Moscow, Russia, ²¹Division of Rheumatology, University Hospital of Padova, Padova, Italy, ²²Marmara University Faculty of Medicine, Rheumatology, Istanbul, Turkey, ²³Department of Dermatology, University of Cologne, Cologne, Germany, ²⁴University Hospital of Cagliari, Rheumatology Unit, Monserrato, Italy, ²⁵Krankenhaus St. Josef, Wuppertal, Germany, ²⁶Rheumatology, Emergency County Clinical Hospital Cluj Napoca, Cluj-Napoca, Romania, ²⁷Cattedra di Reumatologia, Dip Clinica e Terapia Medica, Sapienza Università di Roma, Roma, Italy, ²⁸Rheumatologist, Frankfurt, Germany, ²⁹Istituto di Clinica Medica Generale, Ematologia ed Immunologia Clinica, Università Politecnica delle Marche, Ancona, Italy, ³⁰Rheumatology, Hospital Madrid Norte Sanchinarro, Madrid, Spain, ³¹G.T.Popa Center for Biomedical Research, Iasi, Romania, ³²Justus-Liebig-University Giessen, Department of Internal Medicine and Rheumatology, Kerckhoff-Klinik, Bad Nauheim, Germany, Bad-Nauheim, Germany
Background/Purpose: Systemic sclerosis (SSc) can greatly impact the patients’ quality of life due to its multisystem manifestations. The health assessment questionnaire (HAQ) is one of…
Abstract Number: 1891 • 2016 ACR/ARHP Annual Meeting
Excellent Reliability of Semiquantitative Nailfold Capillaroscopy Assessment in a Systemic Sclerosis Cohort – a Pilot Study
Ana Maria Gheorghiu, Raida Oneata, Alina Soare, Rucsandra Dobrota, Liviu Macovei, Mihaela Milicescu, Mariana Sasu, Marilena Gorga, Ioan Ancuta, Mihai Bojinca, Victor Stoica and Carina Mihai, Carol Davila University of Medicine and Pharmacy, Internal Medicine and Rheumatology Department, Cantacuzino Clinical Hospital, Bucharest, Romania
Background/Purpose: Nailfold capillaroscopy (NFC) is essential in the evaluation and classification of systemic sclerosis (SSc). Semiquantitative capillaroscopy scoring is a promising tool for assessing disease…
Abstract Number: 1892 • 2016 ACR/ARHP Annual Meeting
Immunosignature Technology Differentiates Patients with Systemic Sclerosis and Internal Organ Involvement
Lorinda Chung¹, David Fiorentino², Robert Gerwien³, Kathleen Jia⁴, Joseph Barten Legutki³, Antonio Valenzuela Vergara⁴, Lisa Zhu⁴, Theodore M. Tarasow³ and Kathryn Sykes³, ¹Rheumatology, Stanford University Medical Center, Palo Alto, CA, ²Department of Dermatology, Stanford University School of Medicine, Palo Alto, CA, ³HealthTell, Inc, san ramon, CA, ⁴Stanford University Medical Center, Palo Alto, CA
Background/Purpose: Systemic sclerosis (SSc) is a connective tissue disease (CTD) characterized by fibrosis, vascular complications, and inflammation affecting both skin and internal organs. Diagnosis of…
Abstract Number: 1893 • 2016 ACR/ARHP Annual Meeting
Prevalence of Antiphospholipid Antibodies in Systemic Sclerosis: A Systematic Review and Meta-Analysis
Angélique Lemaire^1,2, Vincent Sobanski^2,3,4,5, Luc Dauchet⁶, Eric Hachulla^1,2,3,5, Sylvain Dubucquoi^3,5,7, Marc Lambert^1,2,3,5, Pierre-Yves Hatron^1,2,8 and David Launay^1,2,3,5, ¹CHU Lille, Département de Médecine Interne et Immunologie Clinique, F-59000 Lille, France, Lille, France, ²CHU Lille, Centre national de référence maladies systémiques et auto-immunes rares (sclérodermie systémique), F-59000 Lille, France, Lille, France, ³Inserm, U995, F-59000 Lille, France, Lille, France, ⁴CHU Lille, Département de Médecine Interne et Immunologie Clinique, F-59000 Lille, France, ⁵Univ. Lille, U995, Lille Inflammation Research International Center (LIRIC), F-59000 Lille, France, Lille, France, ⁶CHU Lille, Service d’Epidémiologie, économie de la santé et prevention, F-59000 Lille, France, Lille, France, ⁷CHU Lille, Laboratoire d’Immunologie, F-59000 Lille, France, Lille, France, ⁸Univ Lille, CHU Lille, F-59000 Lille, France, Lille, France
Background/Purpose: Antiphospholipid antibodies (aPL) can be present in the sera of systemic sclerosis (SSc) patients. Important variations of their prevalence are observed in the literature.…
Abstract Number: 1894 • 2016 ACR/ARHP Annual Meeting
Increased Mortality in Systemic Sclerosis Patients with Fibrosing Myopathy
Julie J. Paik¹, Fredrick M. Wigley², Ami A. Shah¹, Andrea Corse³, Laura K. Hummers⁴ and Andrew Mammen⁵, ¹Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ²Rheum Div/Mason F Lord, Johns Hopkins University School of Medicine, Baltimore, MD, ³Neurology, Johns Hopkins University, Baltimore, MD, ⁴Johns Hopkins University School of Medicine, Baltimore, MD, ⁵National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD
Background/Purpose: Skeletal myopathy in systemic sclerosis (SSc) is associated with poor outcomes such as disability. The spectrum of muscle histopathology of weak SSc patients is…
Abstract Number: 1895 • 2016 ACR/ARHP Annual Meeting
Increased CXCL4/PF4 Presence in Systemic Sclerosis and Absence of Heparin Directed Autoantibodies
Boyang Zheng¹, Normand Blais², Jean-Luc Senécal³, Gemma Perez⁴ and Martial Koenig⁵, ¹Division of Internal Medicine, Centre Hospitalier de l'Université de Montréal, Montreal, QC, Canada, ²Hematology, Hôpital Notre-Dame du CHUM, Montreal, QC, Canada, ³Université de Montréal, Montréal, QC, Canada, ⁴Laboratory of autoimmunity, Centre de Recherche du CHUM, Montreal, QC, Canada, ⁵Internal Medicine, Hôpital Notre-Dame du CHUM, Montréal, QC, Canada
Background/Purpose: Platelet factor 4 (PF4), also called CXLC4 is a chemokine that is found in higher levels in systemic sclerosis (SSc) patients and is in…
Abstract Number: 1896 • 2016 ACR/ARHP Annual Meeting
Efficacy of Pulmonary Arterial Hypertension-Specific Drugs Combination Therapy in Survival of Patients with Pulmonary Arterial Hypertension Associated with Systemic Sclerosis and Other Connective Tissue Diseases
Sumiaki Tanaka¹, Yu Matsueda¹, Gakuro Abe², Jun Okada³ and Shunsei Hirohata¹, ¹Rheumatology and Infectious Diseases, Kitasato University School of Medicine, Kanagawa, Japan, ²Kitasato University School of Medicine, Sagamihara, Japan, ³Nutritional management, Kitasato Junior Collage of health and Hygienic Sciences, Minami-Uonuma, Japan
Background/Purpose: Survival of patients with pulmonary arterial hypertension (PAH) associated with connective tissue disease (CTD), especially systemic sclerosis (SSc), is poorer than that of patients…
Abstract Number: 1897 • 2016 ACR/ARHP Annual Meeting
Vitamin-D Levels and Gastrointestinal (GI) Manifestations in Systemic Sclerosis (SSc)
Suzanne Kafaja¹, Aly Aly², Yossra A Suliman³, Mohamed Alemam⁴, Philip J. Clements⁵ and Daniel E. Furst⁶, ¹Medicine/Rheumatology, University of California Los Angeles, David Geffen School of Medicine, Los Angeles, CA, ²Chamblion St,, Alexandria Faculty of Medicine, Alexandria, Egypt, ³Rheumatology and Rehabilitation dept., Rheumatology and Rehabilitation dept. Assiut university hospital, Assiut Egypt, Assiut, Egypt, ⁴Clinical Pathology and Laboratory Medicine Department, Assistant Lecturer, Qena, Egypt, ⁵Medicine, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA, ⁶David Geffen School of Medicine at UCLA, Los Angeles, CA
Background/Purpose: The GI tract is one of the most commonly affected systems in SSc patients. GI disease in SSc patients is thought to be multifactorial…
Abstract Number: 1898 • 2016 ACR/ARHP Annual Meeting
The Lack of Association of Osteoporosis with Proton Pump Inhibitor in Scleroderma: A UK Single Centre Cohort Experience
Ana Afonso¹, Svetlana Nihtyanova², Christopher Denton³ and Voon H. Ong⁴, ¹Internal Medicine, Hospital Pedro Hispano, EPE, Porto, Portugal, ²Centre for Rheumatology and Connective Tissue Diseases, University College London Medical School, Royal Free Hospital, London, United Kingdom, ³Division of Medicine, Centre for Rheumatology and Connective Tissue Disease, University College London, London, United Kingdom, ⁴Rheumatology, UCL Division of Medicine, London, United Kingdom
Background/Purpose: Recent studies suggest that proton pump inhibitor (PPI) use is variably associated with risk of osteoporosis. The aim of this study was to investigate…
Abstract Number: 1899 • 2016 ACR/ARHP Annual Meeting
The Intestinal Involvement in Systemic Sclerosis Is Characterized By a Peculiar Gut Microbiota
Silvia Bosello¹, Francesco Paroni Sterbini², Gerlando Natalello¹, Giovanni Canestrari¹, Federico Parisi¹, Maurizio Sanguinetti³ and Gianfranco Ferraccioli⁴, ¹Division of Rheumatology, Università Cattolica - Fondazione Policlinico Universitario A.Gemelli, Rome, Italy, ²Institute of Microbiology, Università Cattolica - Fondazione Policlinico Universitario A.Gemelli, Rome, Italy, ³Institute of Microbiology, Università Cattolica - Fondazione Policlinico Universitario A Gemelli, Rome, Italy, ⁴Division of Rheumatology - Institute of Rheumatology and Affine Sciences, Catholic University of the Sacred Heart, Rome, Italy
Background/Purpose: Gastrointestinal involvement is recognized as a major cause of morbidity and mortality in systemic sclerosis (SSc). The pathophysiology is still unclear and includes impairment…

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