Abstracts Archive - Page 1535 of 2425 - ACR Meeting Abstracts

Abstract Number: 1763 • 2016 ACR/ARHP Annual Meeting
Long-Term Impact of Belimumab on Health-Related Quality of Life and Fatigue in Patients with Systemic Lupus Erythematosus Following 7 Years of Treatment Exposure: Impact of Clinical Characteristics over Time
Vibeke Strand¹, Pam Berry², Xiwu Lin², Yumi Asukai³, James Fettiplace³ and Sulabha Ramachandran², ¹Stanford University School of Medicine, Palo Alto, CA, ²GSK, Philadelphia, PA, ³GSK, Uxbridge, Middlesex, United Kingdom
Background/Purpose: Despite improvements in medical care leading to improved survival, systemic lupus erythematosus (SLE) adversely affects patients’ health related quality of life (HRQoL). To explore…
Abstract Number: 1764 • 2016 ACR/ARHP Annual Meeting
Effect of Disease Remission on Organ Damage and Quality of Life in Chinese Patients with Systemic Lupus Erythematosus
Chi Chiu Mok¹, Ling Yin Ho², Sau Mei Tse¹ and Kar Li Chan¹, ¹Medicine, Tuen Mun Hospital, Hong Kong, Hong Kong, ²Dept of Medicine, Tuen Mun Hospital, Hong Kong SAR, Hong Kong
Background/Purpose: To study the effect of disease remission on quality of life and organ damage in patients with systemic lupus erythematosus. Methods: Consecutive patients who fulfilled the…
Abstract Number: 1765 • 2016 ACR/ARHP Annual Meeting
Minimal Clinically Important Differences for Generic Patient Reported Outcomes Tools in SLE
Hervé Devilliers¹, Narender Annapureddy² and Meenakshi Jolly³, ¹Department of Internal Medicine and Systemic Diseases, Hôpital François Mitterrand, CHU de Dijon, Dijon, France, ²Rheumatology and Immunology, Vanderbilt University, Nashville, TN, ³Department of Medicine, Section of Rheumatology, Rush University Medical Center, Chicago, IL
Background/Purpose: Patients with Systemic lupus erythematosus (SLE) have significant impairment in quality of life (QOL). Health related QOL (HRQOL) is one of the four established…
Abstract Number: 1766 • 2016 ACR/ARHP Annual Meeting
Impact of Depression on SLE Flares
Shikha Rathi¹, Alexis Zavitsanos², King Soon Goh¹, Roberto Caricchio¹ and Lauren Freid¹, ¹Temple University Hospital, Philadelphia, PA, ²Rheumatology, Temple University Hospital, Philadelphia, PA
Background/Purpose: Neuropsychiatric systemic lupus erythematosus (NPSLE) involves a wide range of peripheral and central neuropsychiatric manifestations. Depression is one of those and is very common…
Abstract Number: 1767 • 2016 ACR/ARHP Annual Meeting
Poor Body Image in Lupus: Is It Disease Activity, Damage, Sleep, Pain, Fatigue, Stress, Function, Medications, Depression or Fibromyalgia?
Stacy Weinberg¹, Nisarg Gandhi², Meenakshi Jolly³, Winston Sequeira² and Shilpa Arora², ¹Rush University Medical Center, Chicago, IL, ²Rheumatology, Rush University Medical Center, Chicago, IL, ³Rush, Chicago, IL
Background/Purpose: Patients with systemic lupus erythematosus (SLE) have poorer body image (BI) than age matched controls. Few studies have been done looking at the effect…
Abstract Number: 1768 • 2016 ACR/ARHP Annual Meeting
Fatigue in SLE Is Associated with Neuropsychiatric Involvement, Pain, Impaired Sleep and a Reduced Quality of Life
Andreas Jönsen¹, Pia C Sundgren², Jessika Nystedt³, Petra Nilsson³, Åsa Lilja⁴ and Anders A. Bengtsson¹, ¹Lund University, Department of Clinical Sciences, Rheumatology, Lund, Sweden, ²Department of Diagnostic Radiology, Lund University, Lund, Sweden, ³Department of Clinical Sciences, Neurology, Lund University, Lund, Sweden, ⁴Center for Primary Health Care Research, Lund University, Malmö, Sweden
Background/Purpose: Fatigue is a major patient complaint in SLE, often severely impacting quality of life and activities including work. In this study, we analyze neuropsychiatric…
Abstract Number: 1769 • 2016 ACR/ARHP Annual Meeting
Fatigue in Anti-Nuclear Antibody Positive Individuals with Insufficient Criteria to Diagnose a Systemic Autoimmune Rheumatic Disease
Rawad Nori¹, Babak Noamani², Dennisse Bonilla², Larissa Lisnevskaia³, Earl Silverman⁴, Arthur Bookman⁵, Sindhu R. Johnson¹, Carolina Landolt-Marticorena² and Joan Wither², ¹Rheumatology, Mount Sinai Hospital and University Health Network, Toronto, ON, Canada, ²Krembil Research Institute, University Health Network, Toronto, ON, Canada, ³Lakeridge Health Services, Oshawa, ON, Canada, ⁴University of Toronto, Toronto, ON, Canada, ⁵Rheumatology, University Health Network, Toronto, ON, Canada
Background/Purpose: Fatigue is a common symptom of Systemic Autoimmune Rheumatic Disease (SARD) and has been proposed to result from the elaboration of pro-inflammatory factors in…
Abstract Number: 1770 • 2016 ACR/ARHP Annual Meeting
The Impact of Comorbidities on Quality of Life in Systemic Lupus Erythematosus in the First 10 Years
Murray Urowitz¹, Dafna D Gladman², Nicole Anderson³, Jiandong Su⁴ and The Systemic Lupus International Collaborating Clinics (SLICC) Group , ¹Medicine, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada, ²University of Toronto, Toronto, ON, Canada, ³Division of Rheumatology, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada, ⁴Rheumatology, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada
The Impact of Comorbidities on Quality of Life in Systemic Lupus Erythematosus in the first 10 years Background/Purpose: The Medical Outcome Survey Short Form…
Abstract Number: 1771 • 2016 ACR/ARHP Annual Meeting
Depression Is Associated with a Poorer with Health-Related Quality of Life in Patients with Systemic Lupus Erythematosus
Yelitza Cecilia Velarde-Mejia¹, Manuel Ugarte-Gil^1,2, Rocio V. Gamboa-Cardenas¹, Francisco Zevallos¹, Mariela Medina¹, Jorge M. Cucho-Venegas¹, José Alfaro¹, Zoila Rodriguez-Bellido^1,3, Cesar A. Pastor-Asurza^1,3 and Risto Perich-Campos^1,3, ¹Rheumatology, Hospital Guillermo Almenara Irigoyen. EsSalud, Lima, Peru, ²Universidad Cientifica del Sur, Lima, Peru, ³Universidad Nacional Mayor de San Marcos, Lima, Peru
Background/Purpose: Systemic lupus erythematosus (SLE) is a complex autoimmune disease with frequent involvement of the central nervous system. Among the items included in the nomenclature…
Abstract Number: 1773 • 2016 ACR/ARHP Annual Meeting
Risk Factors for Cerebrovascular Events in Systemic Lupus Erythematosus: Results from an International, Inception Cohort Study
John G Hanly¹, Qiuju Li², Li Su³, Murray Urowitz⁴, Juanita Romero-Diaz⁵, Caroline Gordon⁶, Sang-Cheol Bae⁷, Sasha Bernatsky⁸, Ann E. Clarke⁹, Daniel J Wallace¹⁰, Joan T. Merrill¹¹, David A. Isenberg¹², Anisur Rahman¹³, Ellen M. Ginzler¹⁴, Paul R. Fortin¹⁵, D Gladman¹⁶, Jorge Sanchez-Guerrero¹⁷, Michelle Petri¹⁸, Ian N. Bruce¹⁹, Mary Anne Dooley²⁰, Rosalind Ramsey-Goldman²¹, Cynthia Aranow²², Graciela S. Alarcon²³, Kristján Steinsson²⁴, Gunnar K. Sturfelt²⁵, Ola Nived²⁶, Susan Manzi²⁷, M Khamashta²⁸, Ronald F. van Vollenhoven²⁹, Asad Zoma³⁰, Guillermo Ruiz-Irastorza³¹, S. Sam Lim³², Murat Inanc³³, Kenneth C. Kalunian³⁴, Diane L. Kamen³⁵, Christine A. Peschken³⁶, Søren Jacobsen³⁷, Anca Askanase³⁸, Chris Theriault³⁹, Vernon Farewell⁴⁰ and Manuel Ramos-Casals⁴¹, ¹Division of Rheumatology, Department of Medicine and Department of Pathology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, NS, Canada, ²MRC Biostatistics Unit, Cambridge, United Kingdom, ³Nova Scotia Rehab Site, Division of Rheumatology, Capital Health and Dalhousie University, Halifax, NS, Canada, ⁴Medicine, Toronto Western Hospital and University of Toronto, Toronto, ON, Canada, ⁵Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico city, Mexico, ⁶NIHR/Wellcome Trust Clinical Research Facility, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom, ⁷Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea, Republic of, ⁸Divisions of Rheumatology and Clinical Epidemiology, McGill University Health Centre, Montreal, QC, Canada, ⁹Division of Rheumatology, University of Calgary, Calgary, AB, Canada, ¹⁰Cedars-Sinai Medical Center, West Hollywood, CA, ¹¹Arthritis and Clinical Immunology Program, Oklahoma Medical Research Foundation, Oklahoma City, OK, ¹²Centre for Rheumatology, Division of Medicine, University College London, London, United Kingdom, ¹³Rayne Institute, Centre for Rheumatology Research, UCL Division of Medicine, London, United Kingdom, ¹⁴Rheumatology, SUNY Downstate Medical Center, Brooklyn, NY, ¹⁵Rheumatology, University of Laval, Quebec, QC, Canada, ¹⁶University of Toronto, Toronto, ON, Canada, ¹⁷Rheumatology, Toronto Western Hospital, Toronto, ON, Canada, ¹⁸Rheumatology Division, Johns Hopkins University School of Medicine, Baltimore, MD, ¹⁹NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom, ²⁰Dooley Rheumatology, Chapel Hill Doctors, Chapel Hill, NC, ²¹FSM, Northwestern University, Chicago, IL, ²²Molecular Medicine and Medicine, Hofstra Northwell School of Medicine, Hempstead, NY, ²³Department of Medicine, Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, Birmingham, AL, ²⁴Rheumatology, Univ. Hospital, Reykjavik, Iceland, ²⁵Department of Rheumatology, Univ Hospital Lund, Lund, Sweden, ²⁶Department of Rheumatology, University Hospital, Lund, Sweden, ²⁷Lupus Center of Excellence, West Penn Allegheny Health System, Pittsburgh, PA, ²⁸Lupus Research Unit, Lupus Research Unit, The Rayne Institute, King's College London School of Medicine, St Thomas' Hospital, London, United Kingdom, ²⁹Unit for Clinical Therapy Research, Inflammatory Diseases (ClinTRID), The Karolinska Institute, Stockholm, Sweden, ³⁰Rheumatology, Hairmyres Hospital, East Kilbride, Great Britain, ³¹Universidad del Pais Vasco, Servicio de Medicina Interna, Hospital de Cruces, Bizkaia, Spain, ³²Medicine, Emory University School of Medicine, Atlanta, GA, ³³Department of Internal Medicine, Division of Rheumatology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey, ³⁴Division of Rheumatology, Allergy & Immunology, UCSD School of Medicine Center for Innovative Therapy, La Jolla, CA, ³⁵Medicine/Rheumatology & Immunology, Medical University of South Carolina, Charleston, SC, ³⁶RR 149G, Univ of Manitoba, Winnipeg, MB, Canada, ³⁷Rheumatology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark, ³⁸Rheumatology, Columbia University Medical Center, New York, NY, ³⁹Medicine, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, NS, Canada, ⁴⁰Medicine, Division of Rheumatology, Capital Health and Dalhousie University, Halifax, NS, Canada, ⁴¹Laboratory of Systemic Autoimmune Diseases “Josep Font”, CELLEX, Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Department of Systemic Autoimmune Diseases, ICMID, Hospital Clinic, Barcelona, Spain, Barcelona, Spain
Background/Purpose: Neuropsychiatric (NP) disease in patients with SLE includes cerebrovascular events (CerVE). We determined the frequency, attribution and risk factors for CerVE in a large,…
Abstract Number: 1774 • 2016 ACR/ARHP Annual Meeting
Chronological Analysis of Damage Accrual in Patientes with Systemic Lupus Erythematosus: Results from the Spanish Registry of Patients with SLE of the Spanish Society of Rheumatology (RELESSER)
JM Pego-Reigosa^1,2, Ana Lois-Iglesias³, Coral Mouriño-Rodriguez⁴, Francisco Javier López Longo⁵, Maria Galindo Izquierdo⁶, Jaime Calvo-Alen⁷, Jacobo de Uña⁸, Vanessa Balboa⁹, Alejandro Olivé¹⁰, Maria Teresa Oton Sanchez¹¹, Jesus Ibañez¹², Maria Loreto Horcada¹³, Ana Sánchez Atrio¹⁴, Carlos Alberto Montilla Morales¹⁵, Rafael-Benito Melero González⁴, Víctor Martínez Taboada¹⁶, Elvira DIez¹⁷, Mónica Fernández de Castro¹⁸, Esther Ruiz Lucea¹⁹, José Hernández Beiraín²⁰, Marian Gantes²¹, Blanca Hernández-Cruz²², Angela Pecondon-Español²³, Nuria Lozano-Rivas²⁴, Gema Bonilla²⁵, Vicente Torrente-Segarra²⁶, Iñigo Rúa-Figueroa²⁷ and RELESSER-EASSER, ¹Rheumatology Section, Hospital de Meixoeiro, Pontevedra, Spain, Vigo, Spain, ²Rheumatology, Instituto de Investigación Biomédica de Vigo(IBIV), Vigo, Spain, ³Rheumatology, University Hospital A Coruña, A Coruña, Spain, ⁴Rheumatology, EOXI Vigo, Vigo, Spain, ⁵Rheumatology, Hospital Gregorio Marañón, Madrid, Spain, ⁶Sociedad Española de Reumatología, Grupo EAS-SER, Spain, Spain, ⁷Rheumatology, Txagorritxu Hospital, Araba, Vitoria, Vitoria, Spain, ⁸Statistics and OR, Vigo University, Vigo, Spain, ⁹Statistics and OR, Viho University, Vigo, Spain, ¹⁰Rheumatology, Hospital Universitario Germans Trias i Pujol, Barcelona, Spain, ¹¹Rheumatology Department. Hospital Universitario Puerta de Hierro Majadahonda, Majadahonda, Spain, ¹²Rheumatology, Hospital Povisa, Vigo, Spain, ¹³Rheumatology, Complejo Hospitalario de Navarra, Pamplona, Spain, ¹⁴University Hospital Príncipe de Asturias, Immune System Diseases, Rheumatology department, Alcalá de Henares, Madrid, Spain, ¹⁵Rheumatology, HOSPITAL CLÍNICO UNIVERSITARIO DE SALAMANCA, Salamanca, Spain, ¹⁶Rheumatology, Hospital Marqués de Valdecilla, Santander, Spain, ¹⁷Hospital de León, León, Spain, ¹⁸Hospital Puerta de Hierro, Madrid, Spain, ¹⁹Hospital de Basurto, Bilbao, Spain, ²⁰Rheumatology, Hospital Insular de Gran Canaria, Las palmas Gran Canarias, Spain, ²¹Rheumatology, Hospital Universitario de Canarias, La Laguna; Tenerife, Spain, ²²Rheumatology, Hospital Universitario Virgen Macarena, Sevilla, Spain, ²³Rheumatology, Hospital Miguel Servet, Zaragoza, Spain, ²⁴Rheumatology, Hospital Virgen de la Arrixaca, Murcia, Spain, ²⁵Rheumatology, Hospital La Paz - IdiPaz, Madrid, Spain, ²⁶Hospital de L'Hospitalet, L'Hospitalet de Llobregat, Spain, ²⁷Rheumatology Division, Hospital Doctor Negrin, Las Palmas GC, Spain
Background/Purpose: Mortality in systemic lupus erythematosus (SLE) has improved over the last decades. Outcome measures as damage became more important. Objectives: To study the manifestations…
Abstract Number: 1775 • 2016 ACR/ARHP Annual Meeting
Smoking As a Predictor of Cutaneous Activity in Systemic Lupus Erythematosus
Shawn Kwatra¹, Michelle Petri² and Wei Fu³, ¹Dermatology, Johns Hopkins University School of Medicine, Baltimore, MD, ²Rheumatology Division, Johns Hopkins University School of Medicine, Baltimore, MD, ³Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD
ACR Abstract Authors: Shawn G. Kwatra1, Wei Fu2, Michelle Petri2 1Department of Dermatology, 2Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD Title:…
Abstract Number: 1776 • 2016 ACR/ARHP Annual Meeting
Analysis of Progressive Brain and Corpus Callosum Atrophy and Association with Th1 and Th2 Cytokines in Systemic Lupus Erythematosus
Mariana Postal¹, Aline Tamires Lapa¹, Karina O. Peliçari¹, Nailu A. Sinicato², Fernando A. Peres¹, Wesley Geraldo Ferreira³, Lilian TL Costallat³, Fernando Cendes³ and Simone Appenzeller⁴, ¹Medicine, State University of Campinas, Campinas, Brazil, ²Pediatrics, State University of Campinas, Campinas, Brazil, ³State University of Campinas, Campinas, Brazil, ⁴Division of Rheumatology, Faculty of Medical Science, State University of Campinas, São Paulo, Brazil
Background/Purpose: The pathophysiology of brain damage SLE is complex. The aim of this study was to determine brain atrophy progression and the association with Th1…
Abstract Number: 1777 • 2016 ACR/ARHP Annual Meeting
The Accumulation of Organ Damage, Public Insurance Enrollment and Youth Are Associated with Increased Hospitalizations in a Population-Based Cohort of Lupus Patient
S. Sam Lim¹, Gaobin Bao¹, Hong J. Kan², Bonnie Pobiner³, Julie Priest⁴, William Eastman³, Kirk Easley⁵ and Cristina Drenkard⁶, ¹Medicine, Emory University School of Medicine, Atlanta, GA, ²John Hopkins University, Baltimore, MD, ³GSK, Research Triangle Park, NC, ⁴WW Epidemiology, GlaxoSmithKline, Durham, NC, ⁵Biostatistics, Emory University, Atlanta, GA, ⁶Emory University School of Medicine, Atlanta, GA
Background/Purpose: Individuals with systemic lupus erythematosus (SLE) are frequently hospitalized. Determining factors associated with hospitalization rates may help to identify patients at highest risk for…
Abstract Number: 1778 • 2016 ACR/ARHP Annual Meeting
Differences Between Early and Late Cardiovascular Disease in a Population-Based Cohort of Systemic Lupus Erythematosus Patients
Shivani Garg¹, Gaobin Bao², Mugisha Niyibizi³, Cristina Drenkard⁴ and S. Sam Lim², ¹Rheumatology, Emory University, Atlanta, GA, ²Medicine, Emory University School of Medicine, Atlanta, GA, ³Emory University, atlanta, GA, ⁴Emory University School of Medicine, Atlanta, GA
Background/Purpose: It has long been known that mortality after years of systemic lupus erythematosus (SLE) is often associated with cardiovascular disease (CVD). Recent studies have…

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