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  • Abstract Number: 2051 • 2017 ACR/ARHP Annual Meeting

    The Lasso Selection Model in Rheumatology Epidemiologic Studies

    Sofia Pedro1, Bella Mehta2, Gulsen Ozen3,4 and Kaleb Michaud1,5, 1National Data Bank for Rheumatic Diseases, Wichita, KS, 2Rheumatology, Hospital of Special Surgery, New York, NY, 3Rheumatology, Marmara University, School of Medicine, Rheumatology, Istanbul, Turkey, 4Department of Rheumatology, University of Nebraska Medical Center, Omaha, NE, 5University of Nebraska Medical Center, Omaha, NE

    Background/Purpose: Selecting the best model in an epidemiologic analysis is challenging as it addresses problems like confounding and allows the estimation of unbiased results. Stepwise…
  • Abstract Number: 2052 • 2017 ACR/ARHP Annual Meeting

    Apply Musculoskeletal Ultrasonography to Predict Chronic Gouty Arthritis in Patients with Chronic Kidney Diseases

    Zheng-Hao Huang1, Chi-Ching Chang2, En Chao3, Hui-Hsun Chiang4, Shu-Yi Lin5, Kun-Lin Wu6, Hsiang-Cheng Chen5, Shi-Jye Chu5, San-Yuan Kao5, Tsung-Yun Hou5, Feng-Cheng Liu5, Chen-Hung Chen7, Deh-Ming Chang8 and Chun-Chi Lu9, 1Division of Rheumatology, Immunology and Allergy, Department of Internal Medicine, Kaohsiung Armed Forces General Hospital; Tri-service general hospital, National Defense Medical Center, Taipei, Taiwan, 2Taipei Medical University Hospital, Taipei, Taiwan, 3Tri-Service General Hospital Songshan Branch, Taipei, Taiwan, 4School of Nursing, National Defense Medical Center, Taipei, Taiwan, 5Tri-Service General Hospital, Taipei, Taiwan, 6Armed Forces Taoyuan General Hospital, Taipei, Taiwan, 7Taipei Tzu Chi hospital, Taipei, Taiwan, 8Taipei Veterans General Hospital, Taipei, Taiwan, 9University of Washington; Tri-Service General Hopsital, National Defense Medical Center, Seattle, WA

    Background/Purpose: Gouty arthritis, caused by the deposition of monosodium urate (MSU) monohydrate crystals at joints, is comprised of multiple inflammatory processes in synovium, tendons, cartilages…
  • Abstract Number: 2053 • 2017 ACR/ARHP Annual Meeting

    Computed Tomography Dependent Diagnosis of Crowned Dens Syndrome; A Cervical Manifestation of Patients with Calcium Pyrophosphate Dihydrate Crystal Deposition Disease

    Ammar Haikal1, Brian Everist2, Pim Jetanalin3 and Mehrdad Maz3, 1Department Internal Medicine, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS, 2Department of Radiology (MSK), Department of Radiology (MSK), University of Kansas Medical Center, Kansas City, KS, 3Allergy, Clinical Immunology, and Rheumatology, Division of Allergy, Clinical Immunology and Rheumatology, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS

    Background/Purpose:   Crowned Dens Syndrome (CDS), a variation of Calcium Pyrophosphate Deposition Disease (CPPD), is a radiologic-clinical entity defined by the association of radiological calcifications around…
  • Abstract Number: 2054 • 2017 ACR/ARHP Annual Meeting

    Rapid Tophus Resolution in Chronic Refractory Gout Patients Treated with Pegloticase

    Brian F. Mandell1, Herbert S. B. Baraf2, Anthony Yeo3 and Peter E. Lipsky4, 1Rheumatology, Cleveland Clinic, Cleveland, OH, 2The Center for Rheumatology and Bone Research, Wheaton, MD, 3Horizon Pharma, Lake Forest, IL, 4AMPEL BioSolutions, LLC, Charlottesville, VA

      Background/Purpose: It has been suggested that the velocity of resolution of tophi in chronic tophaceous gout is related to serum uric acid (sUA) levels.1 However,…
  • Abstract Number: 2055 • 2017 ACR/ARHP Annual Meeting

    Omeract Ultrasonographic Criteria for the Diagnosis of Calcium Pyrophosphate Deposition Disease at the Metacarpal-Phalangeal, Wrist, Acromion-Clavicular and Hip Joints: An Inter-Observer and Intra-Observer Reliability Study

    Pascal Zufferey1, Georgios Filippou2, Carlo Alberto Scirè3, Nemanja Damjanov4, MA D'Agostino5, George A. W. Bruyn6, Antonella Adinolfi2, Greta Carrara7, Valentina Di Sabatino8, Andrea Delle Sedie9, Tomas Cazenave10, Carlos Pineda11, Francesco Porta12, Daryl K. MacCarter13, Emilio Filippucci14, Frédérique Gandjbakhch15, Ingrid Moller16, Anthony Reginato17, Mihaela Cosmina Micu18, Mohamed Mortada19, Gaël Mouterde20, Lene Terslev21, Esperanza Naredo22, Valentina Picerno2, Wolfgang A. Schmidt23, Violeta Vlad24, Florentin Ananu Vreju25 and Annamaria Iagnocco26, 1Department of Rheumatology, University Hospital Lausanne, Lausanne, Switzerland, 2University of Siena, Siena, Italy, 3Epidemiology Unit -Italian Society for Rheumatology, Milano, Italy, 4Institute of Rheumatology, Belgrade University School of Medicine, Belgrade, Serbia, 5Rheumatology, Versailles-Saint Quentin en Yvelines University, Boulogne-Billancourt, France, 6Rheumatology, MC Groep, Loenga, Netherlands, 7Epidemiology Unit, Italian Society for Rheumatology, Milano, Italy, 8CMV, Grosseto, Italy, 9University of Pisa, Rheumatology Unit, Pisa, Italy, 10Instituto de Rehabilitación Psicofísica, Buenos Aires, Argentina, 11Biomedical Research, Instituto Nacional de Rehabilitacion, Mexico City, Mexico, 12Hospital of Pistoia, Pistoia, Italy, 13Coeur d'Alene Arthritis Clinic, Coeur d'Alene, ID, 14Clinical Reumatologica, Universita Politecnica delle Marche, Ancona, Italy, 15Service de Rhumatologie, GH Pitié-Salpétrière, MD, Paris, France, 16Instituto de Poal, Barcelona, Spain, 17Rheumatology, Rhode Island Hospital, The Warren Alpert Medical School of Brown University, Providence, RI, 18Division of Rheumatology, Department of Rehabilitation II, Clinical Rehabilitation Hospital, Cluj Napoca, Romania, 19zagazig university, Zagazig, Egypt, 20Rheumatology Department, Hopital Lapeyronie, Montpellier, France, 21Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Denmark, Copenhagen, Denmark, 22Rheumatology Department, Hospital Gregorio Marañón, Madrid, Spain, 23Med Ctr Rheumatology Berlin Buch, Immanuel Krankenhaus Berlin, Berlin, Germany, 24RCRD Research Center, Bucharest, Romania, 25University of Medicine and Pharmacy, Department of Rheumatology, Craiova, Romania, 26Academic Rheumatology Unit, Università degli Studi di Torino, Torino, Italy

    Background/Purpose: The OMERACT US subtask force “US in CPPD” has recently created the definitions for US identification of crystal deposits in joints and tested the…
  • Abstract Number: 2056 • 2017 ACR/ARHP Annual Meeting

    Performance and Validity of Musculoskeletal Ultrasound in the Assessment of Synovial Inflammation in Experimental Acute Gout

    Raquel Largo1, Juan Pablo Medina2, Sandra Perez-Baos2, Victor Najera-Aleson2, Aranzazu Mediero2, Gabriel Herrero-Beaumont1 and Esperanza Naredo3, 1Bone and Joint Research Unit, IIS-Fundacion Jimenez Diaz UAM, Madrid, Spain, 2Joint and Bone Research Unit, IIS-Fundacion Jimenez Diaz UAM, Madrid, Spain, 3Rheumatology, Joint and Bone Research Unit, IIS-FJD, Hospital Universitario Fundación Jiménez Díaz., Madrid, Spain

    Background/Purpose: Musculoskeletal ultrasound (MS-US) has not been validated as a reliable technique to evaluate joint inflammation in an acute gout rabbit model. Rabbit has been…
  • Abstract Number: 2057 • 2017 ACR/ARHP Annual Meeting

    Identification of Urate Deposits in Patients with Asymptomatic Hyperuricemia Using a Dual-Energy CT Scan

    Penny Wang1, Stacy Smith2, Rajesh Garg3, Fengxin Lu1, Alyssa Wohlfahrt1, Anarosa Campos1, Kathleen Vanni4, Zhi Yu5, Daniel H. Solomon1 and Seoyoung C. Kim1, 1Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, 2Radiology, Division of Musculoskeletal Imaging and Intervention, Brigham and Women's Hospital, Boston, MA, 3Division of Endocrinology, Diabetes & Hypertension, Brigham and Women's Hospital, Boston, MA, 4Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA, 5Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA

    Background/Purpose: Serum uric acid (sUA) is a useful indicator of the risk of developing gout.  However, most patients with elevated sUA levels do not have…
  • Abstract Number: 2058 • 2017 ACR/ARHP Annual Meeting

    A Study on Febuxostat Prescribing Practices for Patients with Chronic Gout Previously Managed with Allopurinol at the Veterans Affairs Puget Sound

    Percy Balderia and Elizabeth R. Wahl, Rheumatology, University of Washington School of Medicine, Seattle, WA

    Background/Purpose: American College of Rheumatology (ACR) guidelines recommend use of either allopurinol or febuxostat as first-line approaches to urate lowering therapy in gout. Prior studies…
  • Abstract Number: 2059 • 2017 ACR/ARHP Annual Meeting

    Allopurinol Dose-Titration Patterns Relative to Serum Uric Acid Levels in Gout Patients: US Electronic Health Record Data

    An-Chen Fu, Douglas C.A. Taylor and David S. Reasner, Ironwood Pharmaceuticals, Inc., Cambridge, MA

    Background/Purpose: Gout is the most common form of inflammatory arthritis and is caused by elevated serum uric acid (sUA). Allopurinol is a first-line urate-lowering therapy…
  • Abstract Number: 2060 • 2017 ACR/ARHP Annual Meeting

    Pseudogout Among Patients Fulfilling a Billing Code Algorithm for Calcium Pyrophosphate Deposition Disease (CPPD)

    Sara K. Tedeschi, Daniel H. Solomon and Katherine P. Liao, Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Boston, MA

    Background/Purpose: Calcium pyrophosphate deposition disease (CPPD) has a spectrum of manifestations, of which pseudogout is the most acute inflammatory phenotype. Studies focusing on pseudogout are…
  • Abstract Number: 2061 • 2017 ACR/ARHP Annual Meeting

    Population-Specific Factors Associated with Fractional Excretion of Uric Acid

    Zoe Vincent1, Amanda Phipps-Green2, Lisa K. Stamp3, Tony R. Merriman4 and Nicola Dalbeth1, 1University of Auckland, Auckland, New Zealand, 2University of Otago, Dunedin, New Zealand, 3University of Otago, Christchurch, New Zealand, 4Biochemistry Dept, PO Box 56, University of Otago, Dunedin, New Zealand

    Background/Purpose: For most people with gout, reduced renal clearance of uric acid is a key contributor to hyperuricemia.  It is increasingly recognized that gout has…
  • Abstract Number: 2062 • 2017 ACR/ARHP Annual Meeting

    Flow-Mediated Dilation As a Marker of Endothelial Dysfunction in Gout

    Enrique Calvo Aranda1, Ofelia Carrion2, Afnan Abdelkader2, Jorge Juan González Martín3, Francisco Aramburu3, Marta Valero4, Silvia Rodriguez4, Carolina Marin3, Irene Amil3, Felipe Sainz5 and Paloma Garcia De La Peña3, 1RHEUMATOLOGY, Hospital Madrid Norte Sanchinarro, Madrid, Spain, 2Vascular Surgery Department, Hospital Madrid Norte Sanchinarro, Madrid, Spain, 3Rheumatology, Hospital Madrid Norte Sanchinarro, Madrid, Spain, 4Rheumatology, Hospital Madrid Norte Sanchinarro, MADRID, Spain, 5Vascular Surgery, Hospital Madrid Norte Sanchinarro, MADRID, Spain

    Background/Purpose: Several studies have shown the relationship between gout and increased cardiovascular risk and mortality. Hyperuricemia and crystal-induced synovitis are associated with endothelial dysfunction and…
  • Abstract Number: 2063 • 2017 ACR/ARHP Annual Meeting

    Relation of Serum Urate and Gout Duration to Tophi, Urate Deposition, and Inflammation

    Ana Beatriz Vargas-Santos1, S. Reza Jafarzadeh2, Geraldo Castelar-Pinheiro1, Nicola Dalbeth3, William J. Taylor4, Jaap Fransen5, Tim L. Jansen6, H. Ralph Schumacher7 and Tuhina Neogi2, 1Internal Medicine - Rheumatology, State University of Rio de Janeiro, Rio de Janeiro, Brazil, 2Clinical Epidemiology Research and Training Unit, Boston University School of Medicine, Boston, MA, 3University of Auckland, Auckland, New Zealand, 4Department of Medicine, University of Otago, Wellington, New Zealand, 5Department of Rheumatolgy, Radboud University Medical Center, Nijmegen, Netherlands, 6Rheumatology, Radboud University Medical Center, Nijmegen, Netherlands, 7Medicine, Rheumatology, U Penn & VA Med Ctr, Philadelphia, PA

    Background/Purpose: Gout duration and serum urate (SU) levels are thought to influence development of tophi and chronic inflammatory gouty arthropathy, but the extent to which…
  • Abstract Number: 2064 • 2017 ACR/ARHP Annual Meeting

    The Nomenclature of Gout: A Content Analysis of Contemporary Medical Journals

    David Bursill1,2, William J. Taylor3, Robert Terkeltaub4 and Nicola Dalbeth5, 1Medicine, University of Auckland, Auckland, New Zealand, 2School of Medicine, University of Adelaide, Adelaide, Australia, 3University of Otago, Wellington, New Zealand, 4Rheumatology, VA San Diego Healthcare System, San Diego, CA, 5University of Auckland, Auckland, New Zealand

    Background/Purpose: Gout has been recognized and described since antiquity. However, the terms used to describe the disease lack standardization. The aim of this study was…
  • Abstract Number: 2065 • 2017 ACR/ARHP Annual Meeting

    Higher Urate Volume Measured By Dual Energy Computed Tomography Is Associated with Unfavourable Cardiovascular Risks in Patients with Gout

    Sang Heon Lee1, Hae-Rim Kim2, Kyung-Ann Lee3 and Jin Wuk Hur4, 1Division of Rheumatology, Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea, Republic of (South), 2Division of Rheumatology, Department of Internal Medicine, Konkuk University Medical Center, Seoul, Korea, Republic of (South), 3Department of Nuclear medicine, Konkuk University Medical center, seoul, Korea, Republic of (South), 4Rheumatology, Eulji University College of Medcine, Seoul, Korea, Republic of (South)

    Background/Purpose: Hyperuricemia and gout are associated with increased risk of cardiovascular disease. The aim of the study was to evaluate the correlation between cardiovascular risk…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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