Abstracts Archive - Page 1510 of 2425 - ACR Meeting Abstracts

Abstract Number: 1387 • 2016 ACR/ARHP Annual Meeting
Evaluation of Mild to Moderate SLE Flare in Patients with Childhood-Onset Disease
Malki Peskin¹, Dawn Wahezi^2,3, Chaim Putterman⁴, Tamar Rubinstein^5,6 and Nicole Jordan^4,7, ¹Pediatrics, Albert Einstein College of Medicine, Bronx, NY, ²Pediatric Rheumatology, The Children's Hospital at Montefiore, Bronx, NY, ³Pediatric Rheumatology, Albert Einstein College of Medicine, Bronx, NY, ⁴Division of Rheumatology, Albert Einstein College of Medicine, Bronx, NY, ⁵Pediatric Rheumatology, Children's Hospital at Montefiore, Bronx, NY, ⁶Rheumatology, Albert Einstein College of Medicine, Bronx, NY, ⁷Montefiore Medical Center, New York, NY
Background/Purpose: One aspect of childhood SLE lacking understanding is the prediction of disease flares. The objective of this study is to identify predictors of mild…
Abstract Number: 1388 • 2016 ACR/ARHP Annual Meeting
Distinct Clinical Correlates of Immune Thrombocytopenic Purpura at Diagnosis of Childhood-Onset and Adult SLE
Gladys Esteves¹, Natali W. Gormezano², Oriany Pereira¹, David Kern¹, Katia T. Kozu², Rosa M R Pereira³, Clovis A Silva⁴, Eloisa Bonfa⁵ and Nadia E Aikawa⁶, ¹University of São Paulo, São Paulo, Brazil, ²Pediatric Rheumatology Unit, University of São Paulo, São Paulo, Brazil, ³Rheumatology, University of São Paulo, São Paulo, Brazil, ⁴Pediatric Rheumatology Unit, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ⁵Rheumatology Divison, Hospital das Clinicas, Faculdade de Medicina, University of São Paulo, São Paulo, Brazil, ⁶Rheumatology Division, University of São Paulo, São Paulo, Brazil
Background/Purpose: Hematologic abnormalities are common manifestations in systemic lupus erythematosus (SLE) patients. Several studies have demonstrated a higher frequency of immune thrombocytopenic purpura (ITP) in…
Abstract Number: 1389 • 2016 ACR/ARHP Annual Meeting
Alterations in Nailfold Capillaroscopy in Childhood-Onset Systemic Lupus Erythematosus: The Role of Disease Activity in a Prospective Study
Nadia E Aikawa¹, Luiz Sousa², Mariana O Perez³, Ana Paula Luppino-Assad⁴, Rosa M R Pereira⁵ and Maria Teresa Caleiro², ¹Pediatric Rheumatology, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ²Rheumatology Division, University of São Paulo, São Paulo, Brazil, ³Rheumatology Divison, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ⁴Division of Rheumatology, University of São Paulo, sao paulo, Brazil, ⁵Rheumatology, University of São Paulo, São Paulo, Brazil
Background/Purpose: The association between disease activity and nailfold capillaroscopy (NC) alterations has been described in systemic lupus erythematosus (SLE). However, data on longitudinal assessment of…
Abstract Number: 1391 • 2016 ACR/ARHP Annual Meeting
Novel Electronic Health Record-Based Method Confirms Increased Renal Disease Burden in Pediatric-Onset Vs. Adult-Onset Patients with Systemic Lupus Erythematosus
April Barnado¹, Robert Carroll², Carolyn Casey¹, Joshua C. Denny² and Leslie J. Crofford³, ¹Medicine, Vanderbilt University Medical Center, Nashville, TN, ²Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, ³Medicine, Vanderbilt University Medical Center, Nasville, TN
Background/Purpose: Children with Systemic Lupus Erythematosus (SLE) are often understudied compared with adults. Using the electronic health record (EHR) can increase sample size and the…
Abstract Number: 1392 • 2016 ACR/ARHP Annual Meeting
Familial Aggregation of Autoimmune Diseases in Childhood and Adulthood Systemic Lupus Erythematosus
Nailu A. Sinicato¹, Luciana de Oliveira², Aline Tamires Lapa², Lilian Tereza Costallat³, Roberto Marini Sr.⁴, Timothy B. Niewold⁵ and Simone Appenzeller⁶, ¹Pediatrics, State University of Campinas, Campinas, Brazil, ²Medicine, State University of Campinas, Campinas, Brazil, ³RUA EZEQUIEL MAGALHAES,26, Unicamp, Campinas, Brazil, ⁴Pediatric Rheumatology Unit, State University of Campinas, São Paulo, Brazil, ⁵Rheumatology and Immunology, Mayo Clinic, Rochester, MN, ⁶Pediatric Rheumatology Unit, State University of Campinas, Campinas, Brazil
Background/Purpose: Genetic factors play a role in SLE, evidenced by the high sibling risk ratio (λs=8–29) and higher concordance rates between monozygotic twins (>35%) compared…
Abstract Number: 1393 • 2016 ACR/ARHP Annual Meeting
Mycophenolic Acid Pharmacokinetics in Childhood-Onset Systemic Lupus Erythematosus Patients of Hispanic Ethnicity in a Single Center
Anna Carmela Sagcal-Gironella¹, Marietta De Guzman¹, Daping Zhang², Lorita Agu² and Diana Chow², ¹Pediatric Immunology, Allergy, and Rheumatology, Baylor College of Medicine, Texas Children's Hospital, Houston, TX, ²Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX
Background/Purpose: Mycophenolic acid (MPA) is the biologically active metabolite of mycophenolate mofetil (MMF), a widely used immunosuppressant in the treatment of childhood-onset systemic lupus erythematosus…
Abstract Number: 1394 • 2016 ACR/ARHP Annual Meeting
A Pilot Study of Consensus Treatment Plans for Induction Therapy in Childhood Proliferative Lupus Nephritis
Jennifer C. Cooper¹, B. Anne Eberhard², Marilynn Punaro³, Stacy P. Ardoin⁴, Hermine I. Brunner⁵, Joyce Hsu⁶, Linda Wagner-Weiner⁷, Kelly Rouster-Stevens⁸, Laura E. Schanberg⁹, Marisa Klein-Gitelman¹⁰, Emily von Scheven¹¹ and CARRA Registry Investigators, ¹Pediatrics, Divison of Rheumatology, University of California, San Francisco, San Francisco, CA, ²Cohen Children's Medical Center of New York, New Hyde Park, NY, ³Texas Scottish Rite Hospital for Children, Dallas, TX, ⁴Pediatric & Adult Rheumatology, Ohio State University, Columbus, OH, ⁵Pediatric Rheumatology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, ⁶Pediatric Rheumatology, Stanford University, Palo Alto, CA, ⁷Pediatric Rheumatology, University of Chicago Hospitals, Chicago, IL, ⁸Pediatric Rheumatology, Emory University School of Medicine, Atlanta, GA, ⁹Pediatrics, Duke Medical Center, Durham, NC, ¹⁰Division of Rheumatology, Department of Pediatrics, Ann & Robert H. Lurie Children’s Hospital of Chicago/Northwestern University Feinberg School of Medicine, Chicago, IL, ¹¹Division of Rheumatology, Department of Pediatrics, University of California, San Francisco, San Francisco, CA
Background/Purpose: Childhood-onset systemic lupus erythematous (cSLE) patients are at higher risk for renal disease than those with adult-onset disease. Mycophenolate mofetil (MMF) and intravenous…
Abstract Number: 1395 • 2016 ACR/ARHP Annual Meeting
Regional Brain Gray Matter Volume Loss in Children and Adolescents with SLE
Andrea Knight¹, Michelle Vickery², Jimit Doshi³, Guray Erus⁴, Arastoo Vossough⁵ and Susan Furth⁶, ¹Center for Pediatric Clinical Effectiveness, Children's Hospital of Philadelphia, Philadelphia, PA, ²PolicyLab, Children's Hospital of Philadelphia, Philadelphia, PA, ³Section of Biomedical Image Analysis, University of Pennsylvania, Philadelphia, PA, ⁴Section on Biomedical Image Analysis, University of Pennsylvania, Philadelphia, PA, ⁵Radiology, Children's Hospital of Philadelphia, Philadelphia, PA, ⁶Division of Nephrology, Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA
Background/Purpose: Neuropsychiatric SLE in children and adolescents presents diagnostic challenge due to limitations of conventional magnetic resonance imaging (MRI) to detect clinically relevant brain changes.…
Abstract Number: 1396 • 2016 ACR/ARHP Annual Meeting
Cognitive Function in Children with SLE Nephritis: A Cross-Sectional Comparison to Children with Other Glomerular Chronic Kidney Diseases
Andrea Knight^1,2,3, Matthew Matheson⁴, Susan Furth⁵, Brad Warady⁶, Stephen Hooper⁷ and Amy Kogon⁸, ¹Division of Pediatric Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, ²PolicyLab, Children's Hospital of Philadelphia, Philadelphia, PA, ³Center for Pediatric Clinical Effectiveness, Children's Hospital of Philadelphia, Philadelphia, PA, ⁴Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, ⁵Division of Nephrology, Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, ⁶Division of Nephrology, Children's Mercy Hospital, Kansas City, MO, ⁷Department of Allied Health Sciences, University of North Carolina School of Medicine, Chapel Hill, NC, ⁸Division of Nephrology, Nationwide Children's Hospital, The Ohio State University College of Medicine, Columbus, OH
Background/Purpose: Children with lupus nephritis (LN) are at risk for cognitive impairment due to effects on the brain from systemic inflammation and from potential effects…
Abstract Number: 1397 • 2016 ACR/ARHP Annual Meeting
Correlation and Responsiveness of Cutaneous Lupus Disease Area and Severity Index (CLASI) and Skindex-29 with Cutaneous Childhood Lupus Erythematosus (cSLE)
Ashwaq Aleed, CCHMC, cincinnati, OH; Pediatric, Qassim University, Qassim, Saudi Arabia
Correlation and Responsiveness of Cutaneous Lupus Disease Area and Severity Index (CLASI) and Skindex-29 with Cutaneous Childhood Lupus Erythematosus (cSLE) *Ashwaq AlEÕed, **Nora Al Mutairi ,…
Abstract Number: 1398 • 2016 ACR/ARHP Annual Meeting
Practice-Based Differences Between Pediatric Rheumatologists and Dermatologists Caring for Children with Discoid Lupus
Lisa Arkin¹, Kaveh Ardalan², Heather Brandling-Bennett³, Yvonne Chiu⁴, Benjamin Chong⁵, Megan Curran⁶, Raegan Hunt⁷, Amy Paller⁸, Victoria P. Werth^9,10, Marisa Klein-Gitelman⁶, Emily von Scheven¹¹ and for the CARRA SLE workgroup, ¹Department of Dermatology and Pediatrics;, University of Wisconsin School of Medicine & Public Health/American Family Children’s Hospital, Madison, WI, ²Division of Rheumatology; Department of Pediatrics, Ann & Robert H. Lurie Children’s Hospital of Chicago/Northwestern University Feinberg School of Medicine, Chicago, IL, ³Division of Dermatology; Department of Pediatrics, Seattle Children’s Hospital/University of Washington School of Medicine, Seattle, WA, ⁴Department of Dermatology and Pediatrics, Medical College of Wisconsin / Children's Hospital of Wisconsin, Milwaukee, WI, ⁵Dermatology, University of Texas Southwestern Medical Center, Dallas, TX, ⁶Division of Rheumatology, Department of Pediatrics, Ann & Robert H. Lurie Children’s Hospital of Chicago/Northwestern University Feinberg School of Medicine, Chicago, IL, ⁷Departments of Dermatology and Pediatrics, Baylor College of Medicine / Texas Children’s Hospital, Houston, TX, ⁸Departments of Dermatology and Pediatrics, Northwestern University Feinberg School of Medicine/Ann and Robert H. Lurie Children’s Hospital of Chicago, Chicago, IL, ⁹Dermatology, University of Pennsylvania, Philadelphia, PA, ¹⁰Dermatology, Veterans Affairs Medical Center, Philadelphia, PA, ¹¹Division of Rheumatology, Department of Pediatrics, University of California, San Francisco, San Francisco, CA
Background/Purpose: Discoid lupus erythematosus (DLE) is rare in children. There are no consensus guidelines for management or screening for evolution to systemic lupus erythematosus (SLE).…
Abstract Number: 1399 • 2016 ACR/ARHP Annual Meeting
Transitioning Lupus Patients from Pediatric to Adult Rheumatology
Joyce Hui-Yuen¹, Ashlea Cook², Lisa F. Imundo³, Amy Starr², Andrew Eichenfield⁴ and Anca D. Askanase⁵, ¹North Shore-Long Island Jewish Health System, Lake Success, NY, ²Pediatric Rheumatology, Columbia University Medical Center, New York, NY, ³Assoociate Professor of Pediatrics in Medicine - Rheumatology, Columbia University Medical Center, New York, NY, ⁴Morgan Stanley Children's Hospital of NY-Presbyterian, Columbia University, New York, NY, ⁵Department of Medicine, Rheumatology, Columbia University College of Physicians & Surgeons, New York, NY
Background/Purpose: Pediatric rheumatologists have successfully improved the life expectancy and quality of life of children with systemic lupus (cSLE). cSLE has higher morbidity and mortality…
Abstract Number: 1400 • 2016 ACR/ARHP Annual Meeting
Preliminary Validation of the Turkish Simple Measure of Impact of Lupus Erythematosus in Youngsters (SMILEY) in a Single Center
Gozde Yucel¹, Sezgin Sahin², Amra Adrovic², Kenan Barut², Ela Tarakci³, Ahmet Arvas⁴, Nandini Moorthy⁵ and Ozgur Kasapcopur⁶, ¹Istanbul University, Cerrahpasa Medical School, Department of Pediatric Rheumatology, Istanbul, Turkey, ²Pediatric Rheumatology, Istanbul University, Cerrahpasa Medical School, Department of Pediatric Rheumatology, Istanbul, Turkey, ³Istanbul University, Faculty of Health Science, Division of Physiotherapy and Rehabilitation, Istanbul, Turkey, ⁴Istanbul University, Cerrahpasa Medical School, Department of Pediatrics, Istanbul, Turkey, ⁵Robert Wood Johnson Medcal School, Department of Pediatric Rheumatology, New Brunswick, NJ, ⁶Department of Pediatric Rheumatology, Istanbul University, Cerrahpasa Medical School, Department of Pediatric Rheumatology, Istanbul, Turkey
Background/Purpose: Juvenile systemic lupus erythematosus (SLE) is a chronic multisystemic disease with an episodic course which is prevalent in all cultures with wide-ranging effects on…
Abstract Number: 1401 • 2016 ACR/ARHP Annual Meeting
Ultrasonography of Major Salivary Glands in Juvenile SjöGren’s Syndrome − Preliminary Findings in a Multi-Center Study
Daniel S. Hammenfors¹, Valeria Valim², Vibke Lilleby³, Blanca Bica⁴, Sandra Gofinet Pasoto⁵, Clovis Silva⁶, Juan Carlos Nieto⁷, Scott Lieberman⁸, Akaluck Thatayatikom⁹, Roland Jonsson¹⁰, Johan G. Brun¹¹ and Malin V. Jonsson¹², ¹Department of Rheumatology, Haukeland University Hospital, Bergen, Norway, ²Rheumatology, Department of Medicine, Universidade Federal do Espírito Santo, Vitória, Brazil, Vitória, Brazil, ³Rheumatology, Oslo University Hospital, Oslo, Norway, ⁴Hospital Universitário Clementino Fraga Filho, Rio de Janeiro, Brazil, ⁵Internal Medicine, Division of Rheumatology - Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil, ⁶Department of Pediatric Rheumatology, Federal University of São Paulo, São Paulo, Brazil, ⁷Hospital General Universitario Gregorio Marañón and Complutense University, Madrid, Spain, ⁸Pediatrics (Division of Rheumatology), University of Iowa Children's Hospital, Iowa City, IA, ⁹University of Florida, Gainesville, FL, ¹⁰Broegelmann Research Laboratory, Department of Clinical Science, University of Bergen, Bergen, Norway, ¹¹Department of Clinical Science, University of Bergen, Norway, Bergen, Norway, ¹²Department of Clinical Dentistry, Section for Oral and Maxillofacial Radiology, University of Bergen, Bergen, Norway
Background/Purpose: Juvenile Sjögren’s syndrome (jSS) is a rare, poorly defined and possibly underdiagnosed condition. Mean age of diagnosis is approximately 10 years, with major salivary…
Abstract Number: 1402 • 2016 ACR/ARHP Annual Meeting
Meeting the Needs of Adolescents with Autoimmune Diseases, the Development of a Clinical Transition Pathway
Margot Walter¹, Johanna M.W. Hazes², Radboud JEM Dolhain³, Philomine A. van Pelt⁴, A. Dijk van⁵ and Sylvia S.M. Kamphuis⁶, ¹Rheumatology, Erasmus Medical Center, Rotterdam, Netherlands, ²Department of Rheumatology, Erasmus University Medical Centre, Rotterdam, Netherlands, ³Rheumatology, University Medical Center Rotterdam, Rotterdam, Netherlands, ⁴Rheumatology, Erasmus MC, Rotterdam, Netherlands, ⁵Sophia Children's Hospital, Erasmusmc, Rotterdam, Netherlands, ⁶Pediatric Rheumatology, Sophia Children's Hospital – Erasmus University Medical Centre, Rotterdam, Netherlands
Background/Purpose: Evidence based recommendations for transitional programs are available. Despite this, half of Young People (YP) do not make a successful transfer and implementation of…

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