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  • Abstract Number: 1136 • 2017 ACR/ARHP Annual Meeting

    Urate-Lowering Treatment and Risk of Total Joint Replacement in Patients with Incident Gout: A Population-Based Cohort and Nested Case-Control Study

    Jung-Sheng Chen, Chang-Fu Kuo, Ping-Han Tsai, Shue-Fen Luo and Kuang-Hui Yu, Division of Rheumatology, Allergy and Immunology, Chang Gung Memorial Hospital, Taoyuan, Taiwan

    Background/Purpose: This cohort study aimed to investigate the risk of total joint (hip/knee) replacement (TJR, THR and TKR) among patients with incident gout at initial…
  • Abstract Number: 1137 • 2017 ACR/ARHP Annual Meeting

    Urate Lowering to ACR-Recommended Targets Allows Significant Improvement of Severe Gout: A Monocentric Prospective Trial in Vietnam, Using a Systematic Treatment Protocol

    Thomas Bardin1,2,3, Quang Nguyen Dinh1, Khoi Tran Minh1, Nghia Le Hieu1, Minh Do Duc4, Pascal Richette5,6 and Matthieu Resche-Rigon3,7, 1French-Vietnamese Gout Research Center, Ho Chi Minh City, Viet Nam, 2Rheumatology, Hôpital Lariboisière, Paris, France, 3Université Paris Diderot, Paris, France, 4Molecular Biology, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Viet Nam, 5Rhumatologie, Hôpital Lariboisière, Paris, France, 6Rheumatology Department, Université Paris Diderot, Paris, France, 7Biostatistics, Hôpital Saint-Louis, Paris, France

    Background/Purpose: Gout is frequent and severe in Vietnam, where urate-lowering drugs (ULD) are seldom used and many patients are treated only with traditional herbal medicine.…
  • Abstract Number: 1138 • 2017 ACR/ARHP Annual Meeting

    Investigation on Allele Frequency of Rs3117583 and Rs9263726 in Patients with Hyperuricemia or Gout

    Xiaomin Li1, Qiujing Wei2, Naomi Schlesinger3 and Jieruo Gu2, 1Rheumatology, Third affiliated hospital of Sun Yat-sen University, Guangzhou, China, 2Rheumatology, Third affiliated hospital of Sun Yat-sen Universtiy, Guangzhou, China, 3Medicine, Rutgers-Robert Wood Johnson Medical School, New Brunswick, NJ

    Background/Purpose: Allopurinol, effectively regulates and controls serum uric acid levels but may cause allopurinol-induced life-threating severe cutaneous adverse reaction (SCAR). Previous studies reported that single…
  • Abstract Number: 1139 • 2017 ACR/ARHP Annual Meeting

    Management of Gout – a Survey for Healthcare Providers in South Australia

    Nieves Leonardo1 and Julian McNeil2, 1Rheumatology, The Queen Elizabeth Hospital, Woodville South, Australia, 2Rheumatology, Northern Adelaide Local Health Network, Modbury, Australia

    Background/Purpose: Gout is a treatable arthritis and while the rate of gout in Australia has been steadily rising, drugs used to treat acute gouty arthritis…
  • Abstract Number: 1140 • 2017 ACR/ARHP Annual Meeting

    Gout Characteristics and Its Association with the Presence of Cardiovascular Disease: A Case-Control Study

    Mariano Andrés1,2, Salvador López-Salguero1, Francisca Sivera3, Loreto Carmona4, Paloma Vela1,2 and Eliseo Pascual1,5, 1Sección de Reumatología, Hospital General Universitario de Alicante, Alicante, Spain, 2Departamento de Medicina Clínica, Universidad Miguel Hernández, Alicante, Spain, 3Sección de Reumatología, Hospital General Universitario de Elda., Elda, Spain, 4Instituto de Salud Musculoesquelética (InMusc), Madrid, Spain, 5Emeritus Professor, Universidad Miguel Hernández, Elche, Spain

    Background/Purpose: Gout is an independent risk factor for any type of cardiovascular disease (CVD). The exact mechanism behind remains to be elucidated, but persistent crystal-related…
  • Abstract Number: 1141 • 2017 ACR/ARHP Annual Meeting

    Initial Results of a Clinical Study to Determine Whether a Tolerizing Regimen of Pegloticase Can Increase the Frequency of Subjects Having Sustained Lowering of Serum Urate

    Kenneth Saag1, Mitchell Feinman2, Alan J. Kivitz3, Herbert S. B. Baraf4, Roy Fleischmann5, Arthur Kavanaugh6 and Peter E. Lipsky7, 1Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, 2ACME Research, LLC, Orangeburg, SC, 3Department of Rheumatology, Altoona Center for Clinical Research, Duncansville, PA, 4Center for Rheumatology and Bone Research, Wheaton, MD, 5Southwestern Medical Center at Dallas, University of Texas, Dallas, TX, 6Medicine, University of California, San Diego, La Jolla, CA, 7AMPEL BioSolutions, LLC, Charlottesville, VA

    Background/Purpose: Pegloticase is a pegylated recombinant mammalian uricase approved for treatment of persons with chronic gout refractory to standard urate lowering therapy1. Despite initial reduction…
  • Abstract Number: 1142 • 2017 ACR/ARHP Annual Meeting

    A Case Control Study of Anakinra Use for Acute Gout in a VA Patient Cohort Reveals Association with East Asian Descent, High Urate Burden, and Increased Co-Morbidities and All-Cause Mortality

    Ena Sharma1 and Robert Terkeltaub2, 1Rheumatology, University Of California San Diego, San Diego, CA, 2Rheumatology, VA San Diego Healthcare System, San Diego, CA

    Background/Purpose: Effectiveness of the IL-1 receptor antagonist anakinra, in resolving flares of acute gout, has been reported in several case series. Here, studying a VA…
  • Abstract Number: 1143 • 2017 ACR/ARHP Annual Meeting

    The Patient Education for Gout Patients Ameliorate the Patients’ Satisfaction and Serum Uric Acid Level

    In-Seol Yoo1, Chan Keol Park2, Jinhyun Kim1, Su-Jin Yoo3, Seung-Cheol Shim1 and Seong Wook Kang2, 1Division of Rheumatology, Department of Internal Medicine, Daejeon Rheumatoid & Degenerative Arthritis Center, Chungnam National University Hospital, Daejeon, Korea, Republic of (South), 2Internal medicine, Daejeon Rheumatoid & Degenerative Arthritis Center, Chungnam National University Hospital, Daejeon, Korea, Republic of (South), 3Rheumatology, Daejeon Rheumatoid & Degenerative Arthritis Center, Chungnam National University Hospital, Daejeon, Korea, Republic of (South)

    Background/Purpose: The poor adherence to urate lowering therapy is due to a lack of appropriate information. This study performed to analyze the effect of education…
  • Abstract Number: 1144 • 2017 ACR/ARHP Annual Meeting

    Initiating Colchicine and Urate-Lowering Therapy Reduces Baseline Inflammation, and Improves Vascular Endothelial but Not Smooth Muscle Function in Gout Subjects: Resistance to Endothelial Improvement Among Patients with Cardiovascular Comorbidities

    Talia Igel1,2, Aaron Garza Romero2, Virginia Pike3, Yu Guo4, Stuart Katz5, Binita Shah5, Irina Dektiarev5, Svetlana Krasnokutsky Samuels2 and Michael Pillinger2, 1Medicine, Monash University School of Medicine, Melbourne, Australia, 2Medicine/Rheumatology, New York University School of Medicine, New York, NY, 3Medicine/Rheumatology, New York University School of Medicine, Division of Rheumatology, New York, NY, 4Population Health/Statistics, New York University School of Medicine, New York, NY, 5Medicine/Cardiology, New York University School of Medicine, New York, NY

    Background/Purpose: We have previously reported that patients with gout have impaired vascular endothelial and smooth muscle responsiveness, but whether initiating appropriate gout therapy ameliorates these…
  • Abstract Number: 1145 • 2017 ACR/ARHP Annual Meeting

    Effectiveness of a Multidisciplinary Gout Clinic on Timely Achievement of Serum Uric Acid Goals

    Kah Mun Cheong1, Archana Vasudevan2, Melonie Sriranganathan2, Elena Lee1, Serene Yeow1 and Prista Ramskay1, 1Department of Pharmacy, Changi General Hospital, Singapore, Singapore, Singapore, 2Department of Medicine, Changi General Hospital, Singapore, Singapore, Singapore

    Background/Purpose: The concept of a multidisciplinary gout clinic is relatively new in Singapore. Changi General Hospital launched such a clinic in 2014 to provide treat-to-target…
  • Abstract Number: 1146 • 2017 ACR/ARHP Annual Meeting

    Associations between Gout and Cancer in an Nhanes Cohort

    Patricia Kachur1, Venkatesh Gondhi2, Yinjin Wert3 and Pramil Cheriyath2, 1Internal Medicine, Ocala Regional Medical Center, Ocala, FL, 2Ocala Regional Medical Center, Ocala, FL, 3Pinnacle Health System, Harrisburg, PA

    Background/Purpose: Gout is the most common inflammatory disease in the United States (US), affecting more than 4% of the population. Although uric acid (UA) can…
  • Abstract Number: 1147 • 2017 ACR/ARHP Annual Meeting

    Macrophage Activation Syndrome or Acquired Hemophagocytic Lymphohistiocytosis in Adults: Demographics, Clinical Characteristics, and Survivorship in an American Academic Medical Center

    Seema Malkana1 and Irene Tan2, 1Internal Medicine, Temple University Hospital, Philadelphia, PA, 2Section of Rheumatology, Temple University Lewis Katz School of Medicine, Philadelphia, PA

    Background/Purpose:  Macrophage Activation Syndrome, also known as acquired Hemophagocytic Lymphohistiocytosis in adults, is an immune-mediated systemic inflammatory state. It is associated with multisystem organ failure…
  • Abstract Number: 1148 • 2017 ACR/ARHP Annual Meeting

    Arthritis after Cancer Immunotherapy: Symptom Duration and Treatment Response

    Melanie H. Smith1 and Anne R. Bass2,3, 1Medicine, New York Presbyterian Hospital (Cornell), New York, NY, 2Rheumatology, Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, 3Rheumatology, Hospital for Special Surgery Weill Cornell Medical College, New York, NY

    Background/Purpose: Checkpoint inhibitor immunotherapy has fundamentally changed the treatment for an actively expanding list of cancers, however its use is associated with immune related adverse…
  • Abstract Number: 1149 • 2017 ACR/ARHP Annual Meeting

    Clinical Implications of Ultrasonography (US) in Monitoring Disease Activity of Relapsing Polychondritis (RP) and Comparative Investigation By US between Auricle of RP, Repeated Trauma and Healthy Subject

    Eri Amano1, Yoshinori Taniguchi2, Satoshi Inotani1, Hirofumi Nishikawa1, Tatsuki Matsumoto3, Shuichi Nakayama4 and Yoshio Terada5, 1Endocrinology, Metabolism, Nephrology and Rheumatology, Kochi Medical School, Nankoku, Japan, 2Endocrinology, Metabolism,Nephrology and Rheumatology, Kochi University, Kochi, Japan, 3Endocrinology, Metabolism, Nephrology and Rheumatology, Kochi University, Nankoku, Japan, 4Kochi Medical School, Nankoku, Japan, 5Kochi University, Nankoku, Japan

    Background/Purpose: Relapsing polychondritis (RP) is a rare systemic inflammatory disorder and might often be refractory. Therefore, the discovery of more convenient imaging modality than contrast-CT,…
  • Abstract Number: 1150 • 2017 ACR/ARHP Annual Meeting

    Ocular Involvement Is Exclusive with Genital Ulcer and Skin Lesion in the Early Phase of Behçet’s Disease: Nationwide Japanese Registration.

    Nobuyuki Horita1, Akiko Suwa2, Mitsuhiro Takeno3, Takehito Ishido2, Yohei Kirino4 and Nobuhisa Mizuki5, 1National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, 2Department of Ophthalmology and Visual Science, Yokohama City University Graduate School of Medicine, Yokohama, Japan, 3Department of Allergy and Rheumatology, Nippon Medical School Graduate School of Medicine, Tokyo, Japan, 4Department of Stem Cell and Immune Regulation, Yokohama City University Graduate School of Medicine, Yokohama, Japan, 5Yokohama City University, Yokohama, Japan

    Background/Purpose: Behçetfs disease (BD) is a chronic inflammatory syndrome with features of multi-organ involvement and presents with mucocutaneous and ocular symptoms. We have previously found…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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