Abstracts Archive - Page 1463 of 2425 - ACR Meeting Abstracts

Abstract Number: 679 • 2016 ACR/ARHP Annual Meeting
Diagnostic Value of MR Enterography As a Complementary Intervention to Colonoscopy in Axial Spondylarthritis Patients with Chronic Non-Bloody Diarrhea
Ilkay Ergenç¹, Ali Ugur Unal², Zeynep Erturk³, Gulsum Oguz⁴, Yasemin Yalcinkaya⁵, Nese Imeryuz⁶, Rabia Ergelen⁷, Gazanfer Ekinci⁸, Nevsun Inanc⁵, Cigdem Celikel⁹, Haner Direskeneli¹⁰, Hakan Akin¹¹ and Pamir Atagunduz⁵, ¹Internal Medicine, Marmara University School of Medicine, Istanbul, Turkey, ²Marmara University, School of Medicine, Rheumatology, Istanbul, Turkey, ³Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey, ⁴Rheumatology, Marmara University School of Medicine, Istanbul, Turkey, ⁵Department of Rheumatology, Marmara University Faculty of Medicine, Istanbul, Turkey, ⁶Gastroenterology, Marmara University, Istanbul, Turkey, ⁷Radiology, Marmara University School of Medicine, Istanbul, Turkey, ⁸Marmara University Faculty of Medicine Department of Radiology, Istanbul, Turkey, ⁹Pathology, Marmara University School of Medicine, Istanbul, Turkey, ¹⁰Rheumatology, Marmara University, School of Medicine, Istanbul, Turkey, ¹¹Gastroenterology, Marmara University School of Medicine, Istanbul, Turkey
Background/Purpose: Chronic intermittent diarrhea (CID) is a common clinical problem in axial spondylarthritis (axSpA) patients and eventually up to 13% of these are diagnosed with…
Abstract Number: 680 • 2016 ACR/ARHP Annual Meeting
Development and Preliminary Validation of the Computed Tomography Sacroiliac Structural Score for Assessment of Structural Lesions in Axial Spondyloarthritis
Walter Maksymowych¹, Marie Raynal², Damien Loeuille³, Maria Antonietta D'Agostino⁴, Joel Paschke⁵ and Robert G Lambert⁶, ¹Medicine, University of Alberta, Edmonton, AB, Canada, ²Rheumatology, CHRU Nancy, Nancy, France, ³Rheumatology, CHRU Vandoeuvre les Nancy, Nancy, France, ⁴Rheumatology, Versailles-Saint Quentin en Yvelines University, Boulogne-Billancourt, France, ⁵CaRE Arthritis, Edmonton, AB, Canada, ⁶Radiology, University of Alberta, Edmonton, AB, Canada
Background/Purpose: Computed tomography (CT) is considered the imaging benchmark for the assessment of certain structural lesions in the sacroiliac joints (SIJ) of patients with axial…
Abstract Number: 681 • 2016 ACR/ARHP Annual Meeting
Can Bridging Syndesmophytes Independantly Affect Spinal Mobility?
Ismail Sari¹, Ahmed Omar¹, Mansour Alazmi¹, Renise Ayearst², Robert D Inman¹ and Nigil Haroon¹, ¹Rheumatology, Toronto Western Hospital, University of Toronto, Spondylitis Clinic, Toronto, ON, Canada, ²Medicine, University Health Network, Toronto, ON, Canada
Background/Purpose: One of the hallmark characteristics of the disease is new bone formation that manifests as syndesmophytes and spinal fusion. Spinal fusion results from bridging…
Abstract Number: 682 • 2016 ACR/ARHP Annual Meeting
Which Is the Most Reliable Imaging Method for Detection of Structural Changes in the Sacroiliac Joints of Patients with Ankylosing Spondylitis? a Cross-Sectional Study Comparing MRI, CT and Conventional Radiographs
Xenofon Baraliakos¹, Florian Hoffmann², Xiaohu Deng³, Yanyan Wang⁴, Feng Huang⁵ and Jürgen Braun², ¹Rheumatology, Rheumazentrum Ruhrgebiet, Herne, Germany, ²Rheumazentrum Ruhrgebiet, Herne, Germany, ³Chinese PLA General Hospital, Chinese PLA General Hospital, Beijing, China, ⁴Rheumatology, Chinese PLA General Hospital, Beijing, China, ⁵Chinese PLA General Hospital, Beijing, China
Background/Purpose: Magnetic resonance imaging (MRI) is the gold standard for detection of inflammation and fat metaplasia in the sacroiliac joints (SIJ) and the spine of…
Abstract Number: 683 • 2016 ACR/ARHP Annual Meeting
Risk Factors of Uveitis in Ankylosing Spondylitis
Feng Wang¹, Qin Xue², Li Sun³ and Niansong Wang⁴, ¹Nephrology and Rheumatology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China, ²Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China, ³Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing, China, ⁴Shanghai Jiao Tong University Affiliated Sixth People's Hospital, shanghai, China
Background/Purpose: Uveitis is the most common extra-articular manifestation in patients with ankylosing spondylitis (AS).The prevalence and characteristics of uveitis in AS have been studied in previous literatures while…
Abstract Number: 684 • 2016 ACR/ARHP Annual Meeting
Subchondral Bone Sclerosis on Computed Tomography – Does It Have Any Value in the Diagnosis of Inflammatory Sacroiliitis or Is It a Non-Specific Finding?
Omar Azmat¹, Robert G. Lambert², Zaid Jibri³ and Walter Maksymowych⁴, ¹Diagnostic Imaging, University of Alberta, Edmonton, AB, Canada, ²Radiology, University of Alberta, Edmonton, AB, Canada, ³Diagnostic Imaging, The Ottawa Hospital, Ottawa, ON, Canada, ⁴Medicine, University of Alberta, Edmonton, AB, Canada
Background/Purpose: Sclerosis in the sacroiliac joints (SIJ) on radiography and computed tomography (CT) is common but widely considered a non-specific finding…
Abstract Number: 685 • 2016 ACR/ARHP Annual Meeting
Paradoxical Psoriasis Secondary to Anti-Tnfa Agents in Patients with Ankylosing Spondylitis: A Nationwide Population-Based Cohort Study
Ki-Jo Kim¹, Jung Min Bae², Young Bin Joo³, In-Woon Baek⁴, Kyung-Su Park³ and Chul-Soo Cho⁴, ¹Internal Medicine, St. Vincent’s Hospital, The Catholic University of Korea, Suwon, Korea, The Republic of, ²Dermatology, St. Vincent's Hospital, The Catholic University of Korea, Suwon, Korea, The Republic of, ³Internal Medicine, St. Vincent's Hospital, The Catholic University of Korea, Suwon, Korea, The Republic of, ⁴Internal Medicine, Yeouido St. Mary's Hospital, The Catholic University of Korea, Seoul, South Korea
Background/Purpose: Anti-tumor necrosis factor-alpha (anti-TNFa) agents are established as the mainstay of treatment for ankylosing spondylitis (AS). Recently, paradoxical induction or exacerbation of psoriatic skin…
Abstract Number: 686 • 2016 ACR/ARHP Annual Meeting
Development and Evaluation of the Combined Ankylosing Spondylitis Spine Score (CASSS) for the Assessment of Spinal Radiographic Outcome
Fiona Maas¹, Anneke Spoorenberg^1,2, Elisabeth Brouwer¹, Hendrika Bootsma³, Reinhard Bos², Freke Wink² and Suzanne Arends^1,2, ¹Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands, ²Rheumatology, Medical Center Leeuwarden, Leeuwarden, Netherlands, ³Rheumatology and Clinical Immunology, University of Groningen, University Medical Center Groningen, The Netherlands, Groningen, Netherlands
Background/Purpose: Spinal radiographic progression is a highly variable process in ankylosing spondylitis (AS). Our aim was to develop a combined AS spine score (CASSS) in…
Abstract Number: 687 • 2016 ACR/ARHP Annual Meeting
Safety and Efficacy of Certolizumab Pegol over 204 Weeks in Patients with Axial Spondyloarthritis, Including Ankylosing Spondylitis and Non-Radiographic Axial Spondyloarthritis
Atul A. Deodhar¹, Maxime Dougados², Robert Landewé³, Joachim Sieper⁴, Walter Maksymowych⁵, Martin Rudwaleit⁶, Filip van Den Bosch⁷, Jürgen Braun⁸, Philip J Mease⁹, Alan Kivitz¹⁰, Jessica Walsh¹¹, Owen Davies¹², Bengt Hoepken¹³, Luke Peterson¹⁴ and Désirée van der Heijde¹⁵, ¹Divison of Arthritis and Rheumatic Diseases, Oregon Health and Science University, Portland, OR, ²Rheumatology B Department, Paris-Descartes University, APHP, Cochin Hospital, Paris, France, ³Academic Medical Center, Amsterdam and Zuyderland Medical Center, Heerlen, Netherlands, ⁴Rheumatology Department, Charité – University Medicine Berlin, Berlin, Germany, ⁵Department of Medicine, University of Alberta, Edmonton, AB, Canada, ⁶Klinikum Bielefeld and Charité – University Medicine Berlin, Berlin, Germany, ⁷University Hospital Ghent, Ghent, Belgium, ⁸Rheumazentrum Ruhrgebiet, Herne, Germany, ⁹Swedish Medical Center and University of Washington, Seattle, WA, ¹⁰Altoona Center for Clinical Research, Duncansville, PA, ¹¹Division of Rheumatology, University of Utah School of Medicine, Salt Lake City, UT, ¹²UCB Pharma, Slough, United Kingdom, ¹³UCB Pharma, Monheim, Germany, ¹⁴UCB Pharma, Raleigh, NC, ¹⁵Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: RAPID-axSpA (NCT01087762) investigated the efficacy and safety of certolizumab pegol (CZP) in patients (pts) with axial spondyloarthritis (axSpA), including ankylosing spondylitis (AS) and non-radiographic…
Abstract Number: 688 • 2016 ACR/ARHP Annual Meeting
Spondyloarthritis Research Consortium of Canada (SPARCC) Baseline MRI SI Joint Score ≥2 Better Predicts Response to Golimumab Than Does Assessment of Spondyloarthritis International Society (ASAS) MRI Positivity in Nonradiographic Axial Spondyloarthritis
Walter Maksymowych¹, Anjela Tzontcheva², George Philip², Gina Bergman², Susan Huyck² and Sean P. Curtis², ¹Medicine, University of Alberta, Edmonton, AB, Canada, ²Merck & Co., Inc., Kenilworth, NJ
Background/Purpose: Golimumab (GLM) was shown to be effective for nonradiographic axial spondyloarthritis (nr-axSpA) in a randomized, double-blind, placebo-controlled, phase 3 study (GO-AHEAD; NCT01453725).1 The SPondyloArthritis…
Abstract Number: 689 • 2016 ACR/ARHP Annual Meeting
Relationship Between Infliximab Serum Concentrations and Risk of Infections in Patients Treated for Spondyloarthritis
Theodora Bejan-Angoulvant¹, David Ternant², Fadela Daoued³, Frédéric Medina³, Louis Bernard⁴, Saloua Mammou³, Gilles Paintaud² and Denis Mulleman⁵, ¹Service de Pharmacologie Clinique, CHRU de Tours, Université François-Rabelais de Tours, CNRS 7292, CHRU de Tours, Tours, France, ²Laboratoire de Pharmacologie-Toxicologie, Université François-Rabelais de Tours, CNRS 7292, CHRU de Tours, Tours, France, ³Service de Rhumatologie, Université François-Rabelais de Tours, CHRU de Tours, Tours, France, ⁴Service des Maladies Infectieuses, Université François-Rabelais de Tours, CHRU de Tours, Tours, France, ⁵Service de Rhumatologie, Rheumatology department, François-Rabelais University, CNRS 7292, CHRU de Tours, Tours, France
Background/Purpose: Tumour necrosis factor alpha inhibitors are effective in reducing inflammation in rheumatic diseases while increasing the risk of infections. We aimed to study the…
Abstract Number: 690 • 2016 ACR/ARHP Annual Meeting
Increase in Serum Leptin Levels Is Associated with Radiographic Progression of Male Patients with Ankylosing Spondylitis: A 2-Year Longitudinal Study
Seung-Geun Lee¹, Eun-Kyoung Park², Ji-Heh Park¹, Hee-Sang Tag³ and Geun-Tae Kim⁴, ¹Internal Medicine, Pusan National University School of Medicine, Pusan National University Hospital, Busan, Korea, The Republic of, ²Division of Rheumatology, Department of Internal Medicine, Pusan National University School of Medicine, Busan, Korea, The Republic of, ³Division of Rheumatology, Department of Internal Medicine, Kosin University College of Medicine, Busan, South Korea, ⁴Kosin University College of Medicine, Busan, South Korea
Background/Purpose: The immunomodulatory effects of adipokines have been extensively studied in rheumatic diseases, there is a paucity of information regarding their effects on bone metabolism.…
Abstract Number: 691 • 2016 ACR/ARHP Annual Meeting
ASAS Health Index for Patients with Spondyloarthritis: Translation into Spanish, Validation, Reliability and Construct Validity
Wilson Bautista-Molano^1,2, Robert Landewé³, Uta Kiltz⁴, Rafael Valle-Oñate⁵ and Désirée van der Heijde⁶, ¹Rheumatology, Leiden University Medical Center, Bogotá, Colombia, ²Rheumatology Department School of Medicine HMC / UMNG, Bogotá, Colombia, ³Clinical Immunology and Rheumatology, Amsterdam Rheumatology Center, Amsterdam, Netherlands, ⁴Rheumazentrum Ruhrgebiet, Herne, Germany, ⁵Rheumatology, Rheumatology Department School of Medicine HMC / UMNG, Bogota, Colombia, ⁶Rheumatology, Leiden University Medical Center, Leiden, Netherlands
Background/Purpose: The aim of the study was to develop and validate a Spanish-language translation of the ASAS Heath Index (ASAS-HI) testing its reliability, construct validity…
Abstract Number: 692 • 2016 ACR/ARHP Annual Meeting
Efficacy and Safety of Biological Therapy and Target Synthetic Dmards: A Systematic Literature Review Informing the 2016 Update of the ASAS/EULAR Recommendations for the Management of Axial Spondyloarthritis
Alexandre Sepriano¹, Andrea Regel², Désirée van der Heijde¹, Jürgen Braun², Xenofon Baraliakos², Robert Landewé³, Filip van Den Bosch⁴ and Sofia Ramiro¹, ¹Leiden University Medical Center, Leiden, Netherlands, ²Rheumazentrum Ruhrgebiet, Herne, Germany, ³Department of Rheumatology, Amsterdam Rheumatology Center, Amsterdam, Netherlands, ⁴Rheumatology, Ghent University Hospital, Gent, Belgium
Background/Purpose: As part of the update of the ASAS/EULAR recommendations for the management of axSpA, we performed a systematic literature review to assess the efficacy…
Abstract Number: 693 • 2016 ACR/ARHP Annual Meeting
The Prevalence of Axial and Peripheral Spondyloarthritis in Inflammatory Bowel Disease: A Systematic Review & Meta-Analysis
Maren C. Karreman^1,2, Jolanda J. Luime³, Johanna M.W. Hazes² and Angelique E.A.M. Weel¹, ¹Rheumatology, Maasstad Hospital, Rotterdam, Netherlands, ²Rheumatology, Erasmus University Medical Center, Rotterdam, Netherlands, ³Rheumatology, Erasmus Medical Centre, Rotterdam, Netherlands
Background/Purpose: Inflammatory Bowel Disease (IBD) is a chronic disease that affects up to 0.5% of the population, comprising both Crohn’s Disease (CD) and ulcerative colitis…

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