Abstracts Archive - Page 1434 of 2607 - ACR Meeting Abstracts

Abstract Number: 701 • 2017 ACR/ARHP Annual Meeting
Variability in ICAP (International Consensus on ANA Patterns) Pattern Reporting in Testing for Antinuclear Antibodies (ANA) By Indirect Immunofluorescence Assay (IFA)
Stanley J. Naides¹, Jonathan Genzen², Gyorgy Abel³, Christine Bashleben⁴ and Mohammad Qasim Ansari⁵, ¹Immunology, Quest Diagnostics Nichols Institute, San Juan Capistrano, CA, ²ARUP Laboratories Inc, Salt Lake City, UT, ³Department of Pathology and Laboratory Medicine, Lahey Clinic Burlington, Burlington, VT, ⁴College of American Pathologists, Northfield, IL, ⁵Department of Pathology and Laboratory Medicine, Louis Stokes VAMC, Cleveland, OH
Background/Purpose: ANA IFA pattern may guide clinical evaluation by directing specific antibody testing. ICAP has defined consensus ANA IFA patterns and the level of competency…
Abstract Number: 702 • 2017 ACR/ARHP Annual Meeting
Positive Direct Coombs’ Test in the Absence of Hemolytic Anemia Predicts High Disease Activity and Poor Renal Response in Systemic Lupus Erythematosus
Hironari Hanaoka, Harunobu Iida, Tomofumi Kiyokawa, Yukiko Takakuwa and Kimito Kawahata, Division of Rheumatology and Allergology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan
Background/Purpose: Direct Coombs' test in the absence of hemolytic anemia was newly included in the immunologic criterion of the SLICC/ACR 2012 criteria for SLE. Since…
Abstract Number: 703 • 2017 ACR/ARHP Annual Meeting
Clinical Value of Autoantibodies for Lupus Myelitis and Its Subtypes: A Systematic Review
Hiroshi Oiwa¹, Akira Kuriyama², Tomoyasu Matsubara³ and Eiji Sugiyama⁴, ¹Rheumatology, Hiroshima City Hiroshima Citizens Hospital, Hiroshima, Japan, ²General Medicine, Kurashiki Central Hospital, Kurashiki, Japan, ³Neurology, Hiroshima University Hospital, Hiroshima, Japan, ⁴Department of Clinical Immunology and Rheumatology, Hiroshima University Hospital, Hiroshima, Japan
Background/Purpose: We conducted a systematic review to investigate the clinical value of clinical characteristics and autoantibodies, especially lupus-specific antibodies, for lupus myelitis and its subtypes.…
Abstract Number: 704 • 2017 ACR/ARHP Annual Meeting
Detection of dsDNA Antibodies By New Fluoroimmunoassay with Comparable Diagnostic Sensitivity and Specificity to Farr-Ria
Katja Lakota^1,2, Tanja Kveder², Tinka Svec², Polona Žigon², Ales Ambrozic³, Borut Božič^2,4, Matija Tomšič^2,5, Saša Čučnik^2,4 and Snezna Sodin Semrl^1,2, ¹Faculty of Mathematics, Natural Science and Information Technology, University of Primorska, Koper, Slovenia, ²Department of Rheumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia, ³Department of Rheumatology, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia, ⁴Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia, ⁵University of Ljubljana, Faculty of Medicine, Ljubljana, Slovenia
Background/Purpose: Antibodies against double-stranded deoxyribonucleic acid (anti-dsDNA) are a useful and valuable serological marker for diagnosis of systemic lupus erythematosus (SLE). Studies suggest strong correlation…
Abstract Number: 705 • 2017 ACR/ARHP Annual Meeting
Optimization of a Cost-Effective Diagnostic ANA Algorithm
Mathieu Cauchie¹, Bert Vander Cruyssen², Stefanie Van den Bremt³, Muriel Stubbe⁴, Xavier Bossuyt⁵ and Lieve Van Hoovels³, ¹OLV Hospital, Aalst, Belgium, ²Rheumatology, OLV hospital, Aalst, Belgium, ³Laboratory medicine, OLV Hospital, Aalst, Belgium, ⁴Rheumatology, OLV Hospital, Aalst, Belgium, ⁵Laboratory medicine, University Hospital Leuven, Leuven, Belgium
Background/Purpose: Due to the poor specificity of the anti-nuclear antibodies (ANA) indirect immunofluorescence (IIF) assay, enhanced by the huge increase in ANA requests by non-rheumatologists,…
Abstract Number: 706 • 2017 ACR/ARHP Annual Meeting
Elevated Erythrocyte Sedimentation Rate Among Obese Patients with SLE- Not Always a Marker of Disease Activity
George Stojan¹, Erik Barr² and Michelle Petri³, ¹Medicine, Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, ²Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, MD, ³Medicine (Rheumatology), Division of Rheumatology, Johns Hopkins University School of Medicine, MD, USA, Baltimore, MD
Background/Purpose: Obesity is more common in patients with SLE compared to the general population. The prevalence of obesity among SLE patients is between 28 and…
Abstract Number: 707 • 2017 ACR/ARHP Annual Meeting
Distinctive Features of Positive Anti-Cell Antibody Tests on HEp-2 Cells (HEp-2-ANA) in Patients with Non-Autoimmune Diseases
Renan Agustinelli¹, Sílvia H. Rodrigues², Mônica Prado³, Henrique Mariz⁴ and Luis Eduardo C. Andrade^5,6, ¹Rheumatology Division, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, São Paulo, Brazil, ²Rheumatology Division, Escola Paulista de Medicina, Universidade Federal de São Paulo, Sao Paulo, Brazil, ³Rheumatology Division, Escola Paulista de Medicina - Universidade Federal de São Paulo, Sao Paulo, Brazil, ⁴Internal Medicine Department, Hospital das Clínicas - Universidade Federal de Pernambuco, Recife, Brazil, ⁵Rheumatology Division, Universidade Federal de São Paulo, São Paulo, Brazil, ⁶Immunology Division, Fleury Medicine and Health, São Paulo, Brazil
Background/Purpose: The indirect immunofluorescence (IIF) test for anti-cell or antinuclear (ANA) antibodies on HEp-2 cells (HEp-2-ANA) is considered the gold standard method for ANA detection.…
Abstract Number: 708 • 2017 ACR/ARHP Annual Meeting
Anti-RNP/Sm Antibodies Plus Lupus Anticoagulant As Risk Factor for Thrombosis in Patients with Systemic Lupus Erythematosus
Mari Carmen Zamora-Medina¹, Andrea Hinojosa-Azaola², Carlos Núñez-Álvarez³ and Juanita Romero-Diaz⁴, ¹Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutricion S.Z., Mexico City, Mexico, ²Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, ³Immunology and Rheumatology, Instituto Nacional de Ciencias Medicas y Nutricion S.Z., Mexico city, Mexico, ⁴Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico city, Mexico
Background/Purpose: In a previous study, we identify a potential role of anti-RNP/Sm in combination with LA as risk factor for thrombosis. We aimed to validate…
Abstract Number: 709 • 2017 ACR/ARHP Annual Meeting
Characteristics of Cardiac Diseases in Systemic Lupus Erythematosus and Risk Factors of Different Echocardiographic Features
Nevin Hammam^1,2, Mona H EL zohri³ and Alaa A A Mohamed¹, ¹Rheumatology, Rehabilitation and Physical medicine, Assiut University, Faculty of Medicine, Assiut, Egypt, ²Department of Physical therapy, University of Alberta, Edmonton, AB, Canada, ³Internal medicine department, Assiut University, Faculty of Medicine, Assiut, Egypt
Background/Purpose: Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by involvement of different organs in the body. The cardiovascular (CVD) involvement in SLE is…
Abstract Number: 710 • 2017 ACR/ARHP Annual Meeting
D-Dimer As an Early Marker in Patients with Lupus Mesenteric Vasculitis
Xiaolei Ma¹, Bingzhu Hua¹, Hong Wang¹, Yun Zhu¹, Zhiyong Chen¹ and Lingyun Sun², ¹Department of Rheumatology and Immunology, the Affiliated Drum Tower Hospital, Nanjing University Medical School, Nanjing, China, ²Department of Rheumatology and Immunology, the Affiliated Drum Tower Hospital, Nanjing University Medical School, nanjing, China
Background/Purpose: No early serum marker of accurate diagnosis of lupus mesenteric vasculitis (LMV) contributes to the treatment decision-making process. The study was undertaken to evaluate…
Abstract Number: 711 • 2017 ACR/ARHP Annual Meeting
Prevalence and Risk Factors of Depressive Disorders in Chinese Patients with Systemic Lupus Erythematosus (SLE)
Chi Chiu Mok¹, Yan Tung Lilian Lo², Chi Wai Cheng² and Kam Shan Poon², ¹Medicine, Tuen Mun Hospital, Hong Kong, Hong Kong, ²Psychiatry, Castle Peak Hospital, Hong Kong, Hong Kong
Background/Purpose: Depression is common in SLE but most previous studies utilized self-rated scales for evaluation. Formal diagnosis of depression was not established by psychiatric interviews.…
Abstract Number: 712 • 2017 ACR/ARHP Annual Meeting
Novel Electronic Health Record Method Reveals That dsDNA Antibody-Negative Systemic Lupus Erythematosus Is Associated with Pain, Sleep, and Mood Disorders
April Barnado¹, Robert Carroll², Carolyn Casey³, Joshua C. Denny² and Leslie Crofford¹, ¹Medicine, Vanderbilt University Medical Center, Nashville, TN, ²Biomedical Informatics, Vanderbilt University Medical Center, Nashville, TN, ³Lehigh Valley Health Network, Allentown, PA
Background/Purpose: Systemic lupus is a heterogeneous disease with diverse presentations. Studies have shown that dsDNA antibodies associate with renal disease. However, less is known about…
Abstract Number: 713 • 2017 ACR/ARHP Annual Meeting
Long-Term Outcomes in Prolonged Low Disease Activity Are Comparable to Complete Clinical Remission in Systemic Lupus Erythematosus
Konstantinos Tselios¹, Dafna D Gladman², Zahi Touma³, Jiandong Su⁴, Nicole Anderson² and Murray Urowitz⁵, ¹Medicine, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ³Rheumatology, University of Toronto, Division of Rheumatology, Institute of Health Policy, Management and Evaluation, Toronto, ON, Canada, ⁴University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ⁵Centre for Prognosis Studies in the Rheumatic Diseases, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose: Prolonged clinical remission is a desirable, though rare outcome in systemic lupus erythematosus (SLE). We recently showed that low disease activity (LDA) state confers…
Abstract Number: 714 • 2017 ACR/ARHP Annual Meeting
Prolonged Antimalarial Treatment Is Associated with Increased Risk for Elevated Myocardial Biomarkers in Systemic Lupus Erythematosus
Konstantinos Tselios¹, Dafna D Gladman², Paula Harvey³, Shadi Akhtari³, Jiandong Su⁴ and Murray Urowitz², ¹Medicine, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ²Rheumatology, University of Toronto, Toronto Western Hospital, Toronto, ON, Canada, ³Cardiology, Women's College Hospital, University of Toronto, Toronto, ON, Canada, ⁴University of Toronto, Toronto Western Hospital, Toronto, ON, Canada
Background/Purpose: Antimalarial (AM)-induced cardiomyopathy (AMIC) has been rarely reported in systemic lupus erythematosus (SLE). However, given the large number of patients treated, it seems possible…
Abstract Number: 715 • 2017 ACR/ARHP Annual Meeting
Long-Term Outcome of Demyelnating Syndrome in Systemic Lupus Erythematosus: A Longitudinal Study
Jamal A. Mikdashi¹ and Ipolia Ramadan², ¹Div of Rheumatology, Univ of Maryland Schl of Med, Baltimore, MD, ²National Institue of Health, Rockville, MD
Background/Purpose: Demyelinating syndromes (DS) in systemic lupus erythematosus (SLE) are characterized by inflammation, demyelination and neurodegeneration. Little is known, however, about the tenet of dissemination…

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