Abstract Number: 566 • 2017 ACR/ARHP Annual Meeting
Immune Response to Seasonal Flu Vaccination in Patients with Primary Sjogren’s Syndrome
Background/Purpose: Vaccination of rheumatic patients has been reported to induce lower antibody titers than in healthy individuals. However, studies have primarily included patients treated with…Abstract Number: 567 • 2017 ACR/ARHP Annual Meeting
Minor Salivary Gland Histopathology, Major Salivary Gland Ultrasonography, and Secretory Function in Smoking Patients with Primary Sjögren’s Syndrome
Background/Purpose: Several studies have reported a protective effect of smoking with regard to risk for primary Sjögren’s syndrome (pSS) and minor salivary gland inflammation. To…Abstract Number: 568 • 2017 ACR/ARHP Annual Meeting
Complement Consumption As a Predictor of Pulmonary Manifestation in Patients with Primary Sjögren’s Syndrome: Results from a Unicentric Observational Study
Complement Consumption as a Predictor of Pulmonary Manifestation in Patients with Primary Sjögren’s Syndrome: Results from a Unicentric Observational StudyBackground/Purpose: Primary Sjögren’s syndrome (pSS) may…Abstract Number: 569 • 2017 ACR/ARHP Annual Meeting
Is the Oral Microbiome Involved in the Pathogenesis of Sjogren’s Syndrome?
Background/Purpose: Environmental factors involved in the pathogenesis of primary Sjögren’s syndrome (pSS) are still largely unknown. The oral cavity is the microbial habitat closest to…Abstract Number: 570 • 2017 ACR/ARHP Annual Meeting
Signalling Pathways Identified in Salivary Glands from Primary Sjögren’s Syndrome Patients Reveal Enhanced Adipose Tissue Development, As Demonstrated By Microarray Analysis, Real-Time PCR and Immunohistochemistry
Background/Purpose: : A characteristic feature of Sjögren’s syndrome (SS) is the destruction of salivary and lacrimal glands mediated by mononuclear cell infiltration. Adipocytes can also…Abstract Number: 571 • 2017 ACR/ARHP Annual Meeting
Anti-Modified Protein Antibody Response Pattern in Primary Sjögren’s Syndrome: Clinical and Prognostic Implications
Background/Purpose: Over the last decades, several post translationally modified proteins have been identified as auto-antigens in rheumatoid arthritis (RA). No data regarding Abs against acetylated…Abstract Number: 572 • 2017 ACR/ARHP Annual Meeting
Biopsy Accuracy in Sjögren’s Syndrome: Analysis of 803 Patients Presenting with Sicca Syndrome Referred to Labial Salivary Gland Biopsy
Background/Purpose: Labial salivary gland biopsy (LSGB) is a minimally invasive procedure used in the diagnostic of Sjögren's Syndrome (SS). Objectives: to describe demographic, clinical and…Abstract Number: 573 • 2017 ACR/ARHP Annual Meeting
Subepithelial Infiltrate of the Vagina in Primary Sjogren’s Syndrome: The Cause of Vaginal Dryness?
Background/Purpose: Women with primary Sjögren’s syndrome (pSS) often experience vaginal dryness. The cause of this symptom is unknown. This study compared the vaginal and cervical…Abstract Number: 574 • 2017 ACR/ARHP Annual Meeting
Is Elastography a New Tool to Differentiate Sjögren Syndrome to Sicca Syndrome?: Results of the Elsa (elastography of salivary glands) Study
Background/Purpose: Ultrasonography (US) has been developed in salivary glands (SG) and particularly in primary Sjögren syndrome (pSS) for 10 years. However, the training curve is…Abstract Number: 575 • 2017 ACR/ARHP Annual Meeting
Distinct Clinical and Immunological Features of Anti-Centromere Antibody Positive Primary Sjögren’s Syndrome: A Single Center Cross-Sectional Cohort Study
Background/Purpose: Anti-centromere antibody (ACA) positive Sjögren’s syndrome (SS) is considered as a subtype in SS. Recent international collaborative large scale cohort study highlighted several clinical…Abstract Number: 576 • 2017 ACR/ARHP Annual Meeting
Immunosignature-Based Diagnosis and Prediction of Therapeutic Response Enables Retrospective Patient Stratification in a Phase IIa Clinical Trial for VAY736 in Primary Sjögren’s Syndrome
Background/Purpose: Although patient stratification can improve the success rate of clinical trials, efforts to apply this strategy to autoimmune studies such as Sjögren’s syndrome are…Abstract Number: 577 • 2017 ACR/ARHP Annual Meeting
The Value of C-Reactive Protein As a Predictor of Radiographic Spinal Progression Is Strongly Dependent on β-Fibrinogen and Factor XIII a-Subunit Genotypes in Patients with Axial Spondyloarthritis
Background/Purpose: It has been shown in the past that inflammatory activity (i.e., elevated C-reactive protein) predicts radiographic spinal progression in patients with axial spondyloarthritis (axSpA).…Abstract Number: 578 • 2017 ACR/ARHP Annual Meeting
Added Value of Biomarkers Compared to Routine Clinical Parameters for the Prediction of Radiographic Spinal Progression in Axial Spondyloarthritis
Background/Purpose: Structural damage in the spine is an important determinant of the functional status and spinal mobility in axial spondyloarthritis (axSpA). Already present syndesmophytes, elevated…Abstract Number: 579 • 2017 ACR/ARHP Annual Meeting
Circulating MiR-145 As a Marker of Therapeutic Response to Anti-TNF Therapy in Patients with Ankylosing Spondylitis
Background/Purpose: The altered expression of miRNAs contributes to the pathophysiology of inflammatory conditions. In addition, circulating miRNAs may serve as promising therapeutic and prognostic biomarkers.…Abstract Number: 580 • 2017 ACR/ARHP Annual Meeting
Tenascin-C, a TLR 4 Endogenous Ligand Levels Are Increased in Ankylosing Spondylitis
Background/Purpose: Monocytes of patients with Ankylosing Spondylitis (AS) over-express Toll-like receptor (TLR) 4 on their monocytes. Tenascin-C (TNC) is an extracellular-matrix-glycoprotein and acts as an…
ACR Meeting Abstracts