Abstracts Archive - Page 1409 of 2425 - ACR Meeting Abstracts

Abstract Number: 15 • 2017 Pediatric Rheumatology Symposium
An Internet-based Self-management Program for Adolescents with Juvenile Idiopathic Arthritis – A Randomized Controlled Trial
Jennifer N. Stinson¹, Sarah Campillo², Tania Cellucci³, Paul Dancey⁴, Ciarán M. Duffy⁵, Janet Ellsworth⁶, Brian Feldman⁷, Adam Huber⁸, Nicole Johnson⁹, Patrick McGrath⁸, Alan Rosenberg¹⁰, Natalie J. Shiff¹¹, Lynn R. Spiegel¹², Shirley M.L. Tse¹³, Lori Tucker¹⁴, J. Charles Victor¹⁵ and Stephanie Luca¹⁶, ¹Anesthesia and Pain Medicine, The Hospital for Sick Children, Toronto, ON, Canada, ²Montreal Children's Hospital, Montreal, QC, Canada, ³Pediatrics/Rheumatology, McMaster Children's Hospital, Hamilton, ON, Canada, ⁴Pediatrics, Janeway Children's Hospital, St. John's, NL, Canada, ⁵Children's Hospital of Eastern Ontario and University of Ottawa, Ottawa, ON, Canada, ⁶University of Alberta, Edmonton, AB, Canada, ⁷Department of Rheumatology, Hospital for Sick Children, Toronto, ON, Canada, ⁸IWK Health Centre, Halifax, NS, Canada, ⁹Pediatrics, University of Calgary, Alberta Children's Hospital, Calgary, AB, Canada, ¹⁰Pediatrics, University of Saskatchewan, Saskatoon, SK, Canada, ¹¹University of Florida, Gainesville, FL, ¹²Rheumatology/Pediatrics, The Hospital for Sick Children, Toronto, ON, Canada, ¹³Rheumatology, The Hospital for Sick Children and University of Toronto, Toronto, ON, Canada, ¹⁴Pediatric Rheum/Rm K4-120, BC Childrens Hospital, Vancouver, BC, Canada, ¹⁵University of Toronto, Toronto, ON, Canada, ¹⁶The Hospital for Sick Children, Toronto, ON, Canada
Background/Purpose: Juvenile Idiopathic Arthritis (JIA) is a common chronic childhood illness associated with physical and emotional symptoms that can negatively impact health-related quality of life…
Abstract Number: 6 • 2017 Pediatric Rheumatology Symposium
High Health Care Utilization Preceding Diagnosis of Systemic Lupus Erythematosus in Youth
Joyce Chang^1,2, David Mandell³ and Andrea Knight^4,5,6, ¹Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, ²Children's Hospital of Philadelphia, Philadelphia, PA, ³Psychiatry and Pediatrics, Center for Mental Health Policy and Services Research, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, ⁴Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, ⁵Center for Pediatric Clinical Effectiveness & PolicyLab, Philadelphia, PA, ⁶Division of Pediatric Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA
Background/Purpose: Childhood-onset SLE is associated with high risk for organ damage, which may be mitigated by early diagnosis and treatment. To identify points of health…
Abstract Number: 36 • 2017 Pediatric Rheumatology Symposium
The Association of Obesity with Pediatric Psoriatic Arthritis
Cynthia Manos¹, Rui Xiao², Timothy G. Brandon¹, Alexis Ogdie-Beatty³ and Pamela Weiss⁴, ¹Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, ²Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA, ³Rheumatology, Hospital of the University of Pennsylvania, Philadelphia, PA, ⁴Division of Rheumatology, Center for Pediatric Clincial Effectiveness, Children's Hospital of Philadelphia, Philadelphia, PA
Background/Purpose: Obesity is associated with a significantly increased risk of inflammatory arthritis in adult patients with psoriasis. Obese adults with psoriatic arthritis (PsA) also…
Abstract Number: 156 • 2017 Pediatric Rheumatology Symposium
Teaching High Value Musculoskeletal Care Through Online Simulation Cases
Nilam D Patel¹, Marc Buchner² and Angela B. Robinson³, ¹Case Western Reserve University School of Medicine, Cleveland, OH, ²Department of Electrical Engineering & Computer Science, Case Western Reserve School of Engineering, Cleveland, OH, ³Pediatric Rheumatology, Rainbow Babies and Childrens Hospital, Cleveland, OH
Background/Purpose: Musculoskeletal (MSK) complaints comprise 6-15% of general pediatric visits.1,2 Many MSK complaints can be diagnosed through simple history and physical with limited laboratory and imaging…
Abstract Number: 116 • 2017 Pediatric Rheumatology Symposium
Arthritis as First Presenting Symptom of Inflammatory Bowel Disease: A Case Control Study
Kathryn Phillippi¹, Thomas Sferra², Nora Singer³ and Elizabeth Brooks⁴, ¹Pediatric Infectious Diseases and Rheumatology, Rainbow Babies and Children’s Hospital / Case Medical Center, Cleveland, OH, ²Pediatric Gastroenterology, Rainbow Babies and Children's Hospital/Case Medical Center, Cleveland, OH, ³MetroHealth Medical Center and Case Western Reserve University, Cleveland, Ohio, Cleveland, OH, ⁴Division of Pediatric Infectious Diseases and Rheumatology, Rainbow Babies and Children’s Hospital / Case Medical Center, Cleveland, OH, Cleveland, OH
Background/Purpose: Inflammatory bowel disease (IBD) is associated with extra-intestinal manifestations, the most common of which is arthralgia/arthritis. 4.1- 15% of patients with inflammatory bowel disease…
Abstract Number: 115 • 2017 Pediatric Rheumatology Symposium
Anti-Phospholipid Antibodies in Children with Down Syndrome
Buthaina Al-Adba¹, Haitham El Bashir², Khalid ZahrAldin³, Ronald Thomas^4,5, Mohammad Al-Khalifa⁶, Asmaa Al-Marwani⁶, Dekra Al-Faridi⁶, Muhamad Al Dabbagh⁷ and Basil Fathalla³, ¹Pediatrics - Rheumatology, Hamad Medical Corporation, Doha, Qatar, ²Developmental Pediatrics & Children’s Rehabilitation - Department of Pediatrics, Hamad Medical Corporation, Doha, Qatar, ³Pediatrics, Hamad Medical Corporation, Doha, Qatar, ⁴Department of Research and Biostatistics, Children's Hospital of Michigan, Detroit, MI, ⁵Children's Research Center, Wayne State University, Detroit, MI, ⁶Department of Laboratory Medicine and Pathology, Hamad Medical Corporation, Doha, Qatar, ⁷Department of Pediatrics, Hamad Medical Corporation, Doha, Qatar
Background/Purpose: The prevalence of anti-phospholipid antibodies (APL) in children with Down syndrome (DS) is unknown. Furthermore, it is unknown if an intermittent or persistent presence…
Abstract Number: 123 • 2017 Pediatric Rheumatology Symposium
Acupuncture for Pediatric Chronic Pain Relief: A Review
Yujuan Zhang¹, Stephanie Hyon² and Chenchen Wang³, ¹Pediatric Rheumatology, Tufts Medical Center, Boston, MA, ²Rheumatology, Tufts Medical School, Boston, MA, ³Rheumatology, Tufts Medical Center, Boston, MA
Background/Purpose: Acupuncture, a type of complementary and integrative therapy, has been widely used for pain relief in adults. However, evidence of the effect of acupuncture…
Abstract Number: 57 • 2017 Pediatric Rheumatology Symposium
Quantification of Dynamic MRI examinations in Juvenile Idiopathic Arthritis
Nikolay Tzaribachev¹, Romiesa Hagoug², Polymnia Louka³, Joyee Islam³, Mark Hinton³, Olga Kubassova⁴ and Mikael Boesen⁵, ¹PRI - Pediatric Rheumatology Research Institute, Bad Bramstedt, Germany, ²Imaging, Image Analysis Group, London, United Kingdom, ³Image Analysis Group, London, United Kingdom, ⁴Image Analysis Group, Image Analysis Group, London, England, ⁵Radiology, Copenhagen University Hospital, Bispebjerg and Frederiksberg, Frederiskberg, Denmark
Background/Purpose: In chronic inflammatory conditions, the need for a more objective measurement of disease activity has been identified, where dynamic contrast enhanced (DCE) MRI as…
Abstract Number: 111 • 2017 Pediatric Rheumatology Symposium
Eosinophilic Fasciitis in Children: Clinical Course and Response to Treatment from Two Large Academic Centers
Suhas Ganguli¹, Meiqian Ma², Christine Lauren³, Maria Garzon³, Cassyanne L. Aguiar⁴, Andrew Eichenfield⁵, Amy Starr⁶, Lisa F. Imundo^7,8, B. Anne Eberhard⁹ and Joyce Hui-Yuen¹⁰, ¹Pediatrics, Cohen Children's Medical Center of New York, Lake Success, NY, ²Pediatric Rheumatology, Cohen Children's Medical Center of New York, Lake Success, NY, ³Division of Pediatric Dermatology, Columbia University Medical Center, New York, NY, ⁴Pediatric Rheumatology, Children's Hospital of The King's Daughters, Norfolk, VA, ⁵Columbia University Medical Center, New York, NY, ⁶Pediatric Rheumatology, Columbia University Medical Center, New York, NY, ⁷Pediatrics, Columbia University Medical Center, New York, NY, ⁸Assoociate Professor of Pediatrics in Medicine - Rheumatology, Columbia University Medical Center, New York, NY, ⁹Cohen Children's Medical Center of New York, New Hyde Park, NY, ¹⁰Cohen Children's Medical Center of New York, Lake Success, NY
Background/Purpose: Eosinophilic fasciitis (EF) is a rare connective tissue disease characterized by a progressive inflammatory thickening of skin and soft tissues. The diagnosis is based…
Abstract Number: 149 • 2017 Pediatric Rheumatology Symposium
Deficiency of Complement C4A or Low Copy Number of Total C4 Genes, HLA-DRB1*15 and HLA-DRB1*03 Are Strong Genetic Risk Factors for Pediatric SLE of European Descent
Stacy Ardoin¹, Pinar Ozge Avar Aydin², Lai Hin Kimi Chan³, Katherine Lintner⁴, Yee Ling Wu^5,6, Rabheh Aziz¹, Anjali Patwardhan^7,8, Evan Mulvihill¹, Gakit Yu⁹, Bi Zhou¹⁰, Emeli Lundstrom¹¹, Leonid Padyukov¹², Kyla Driest¹³, Cagri Yildirim-Toruner¹³, Sharon Bout-Tabaku¹³, Charles Spencer¹⁴, Gloria Higgins¹, Sampath Prahalad¹⁵, Hermine Brunner¹⁶ and Chack-Yung Yu^10,17, ¹Pediatrics and Rheumatology, Nationwide Children's Hospital and The Ohio State University, Columbus, OH, ²Rheumatology, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, ³Pediatrics, Emory University School of Medicine, Atlanta, GA, ⁴Pediatrics, Nationwide Children's Hospital, Columbus, OH, ⁵The Research Institute at Nationwide Children's Hospital and The Ohio State University, Columbus, OH, ⁶Center for Molecular and Human Genetics, The Research Institute at Nationwide Children's Hospital, Columbus, OH, ⁷Pediatric Rheumatology, Nationwide Childrens Hospital, Columbus, OH, ⁸Pediatric Rheumatology, Nationwide Children's Hospital, Columbia, MO, ⁹Center for Molecular and Human Genetics, Nationwide Children's Hospital, Columbus, OH, ¹⁰Center for Molecular and Human Genetics, The Research Institute at Nationwide Children's Hospital and The Ohio State University, Columbus, OH, ¹¹Rheumatology, Karolinska Institute, Stockholm, Switzerland, ¹²Rheumatology Unit, Department of Medicine, Karolinska Institutet and Karolinska Hospital, Stockholm, Sweden, ¹³Rheumatology, Nationwide Children's Hospital, Columbus, OH, ¹⁴Rheumatology, Nationwide Childrens Hospital/OSU, Columbus, OH, ¹⁵Pediatrics, Emory Children's Center, Atlanta, GA, ¹⁶Rheumatology, PRCSG, Cincinnati, OH, ¹⁷Pediatrics, Ohio State Univ, Columbus, OH
Background/Purpose: A complete genetic deficiency of complement C4 almost always leads to the pathogenesis of systemic lupus erythematosus (SLE) with childhood onset, although its prevalence…
Abstract Number: 32 • 2017 Pediatric Rheumatology Symposium
High Mobility Group Box 1 Protein in Children with Kawasaki Disease and Systemic Juvenile Idiopathic Arthritis
Hon Yan Ng¹, Stefan Slomp², Tracy Wilson-Gerwing³, Joan Dietz⁴, Abid Lodhi⁵, Tanya Holt⁶ and Alan Rosenberg³, ¹Department of Pediatrics, University of Saskatchewan, Saskatoon, SK, Canada, ²Pediatrics, Emergency Medicine, University of Alberta, Edmonton, AB, Canada, ³Pediatrics, University of Saskatchewan, Saskatoon, SK, Canada, ⁴University of Saskatchewan, Saskatoon, SK, Canada, ⁵Regina Qu'appelle Health Region, Regina, SK, Canada, ⁶University of Saskatchewan, Sasktoon, SK, Canada
Background/Purpose: High Mobility Group Box 1 Protein (HMGB1) is a nuclear protein that stabilizes DNA and modulates gene expression. In sepsis and in certain other…
Abstract Number: 53 • 2017 Pediatric Rheumatology Symposium
A Prospective Study to Assess for Changes in Mood with Initiation of Anti-TNF therapy: A Pilot Study
Kader Cetin Gedik¹, Helen Papaioannou², Monica Marcus³, Clifford Deutschman⁴ and Beth Gottlieb⁵, ¹Pediatric Rheumatology, Cohen Children's Medical Center fo New York, New Hyde Park, NY, ²Developmental and Behavioral Pediatrics, Cohen Children's Medical Center of New York, New Hyde Park, NY, ³Pediatric Immunology, Allergy and Rheumatology, Texas Children's Hospital, Houston, TX, ⁴Center for Pediatric Research, Cohen Chilredn's Medical Center of New York, New Hyde Park, NY, ⁵Pediatric Rheumatology, Cohen Children's Medical Center of New York, New Hyde Park, NY
Background/Purpose: Anti- tumor necrosis factor (anti-TNF) agents have been widely studied in the treatment of juvenile idiopathic arthritis (JIA) and inflammatory bowel disease (IBD). Although there…
Abstract Number: 122 • 2017 Pediatric Rheumatology Symposium
Presenting Manifestations of Amplified Musculoskeletal Pain Syndrome in Males versus Females
Sabrina Gmuca¹, Jenna L. Tress², Jennifer Mosby³, Laura P. Richardson³ and David D. Sherry², ¹Pediatric Rheumatology, The Children's Hospital of Philadelphia, Philadelphia, PA, ²Pediatric Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, ³Seattle Children's Hospital, Seattle, WA
Background/Purpose: Amplified musculoskeletal pain syndrome (AMPS) is a chronic non-inflammatory musculoskeletal pain condition. AMPS has a predilection for females but males can be affected as…
Abstract Number: 78 • 2017 Pediatric Rheumatology Symposium
Predictors of Outcome Following Tonsillectomy in Periodic Fever, Aphthous Stomatitis Pharyngitis, and Cervical Adenitis (PFAPA) Syndrome
Kalpana Manthiram¹, Daniel L. Kastner^2,3 and Kathryn Edwards⁴, ¹National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, ²Inflammatory Disease Section, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD, ³Inflammatory Disease Section, NHGRI/NIH, Bethesda, MD, ⁴Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN
Background/Purpose: Tonsillectomy is considered curative in a majority of patients with periodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA) syndrome. Predictors of outcome following…
Abstract Number: 150 • 2017 Pediatric Rheumatology Symposium
Childhood-onset Takayasu Arteritis Associated with Mutations in CBL
Arturo Borzutzky^1,2, Charlotte Niemeyer³, Guillermo Pérez-Mateluna⁴, Cecilia Mellado⁵, Miriam Erlacher³, Marena Niewisch⁶, Mariana Aracena⁵ and Cristián García⁷, ¹Department of Pediatric Infectious Diseases and Immunology, Pontificia Universidad Católica de Chile, Santiago, Chile, ²Millennium Institute on Immunology and Immunotherapy, Santiago, Chile, ³Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine,, University Medical Center Freiburg, Freiburg, Germany, ⁴Pediatric Infectious Diseases and Immunology, Pontificia Universidad Católica de Chile, Santiago, Chile, ⁵Section of Genetics, Department of Pediatrics, Pontificia Universidad Católica de Chile, Santiago, Chile, ⁶Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, University Medical Center Freiburg, Freiburg, Germany, ⁷Department of Radiology, Pontificia Universidad Católica de Chile, Santiago, Chile
Background/Purpose: Takayasu arteritis (TA) is an inflammatory large-vessel vasculitis of unknown etiology that rarely presents in childhood. No monogenic etiologies of TA have been identified.…

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